Novel motif:35

name:	motif35_CGCCYAGA

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0006353	transcription termination, DNA-dependent	5.088230e-15
GO:2000465	regulation of glycogen (starch) synthase activity	3.373640e-14
GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade	3.173736e-13
GO:0046628	positive regulation of insulin receptor signaling pathway	1.172120e-11
GO:0006616	SRP-dependent cotranslational protein targeting to membrane, translocation	1.437238e-11
GO:0006617	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition	1.437238e-11
GO:0090002	establishment of protein localization in plasma membrane	3.061622e-11
GO:0072661	protein targeting to plasma membrane	3.283383e-11
GO:2000467	positive regulation of glycogen (starch) synthase activity	3.416956e-11
GO:0006369	termination of RNA polymerase II transcription	1.422646e-10
GO:0006406	mRNA export from nucleus	9.167526e-10
GO:0051645	Golgi localization	2.083733e-9
GO:0001522	pseudouridine synthesis	7.177801e-9
GO:0000244	assembly of spliceosomal tri-snRNP	1.665819e-8
GO:0005979	regulation of glycogen biosynthetic process	3.044450e-8
GO:0090150	establishment of protein localization in membrane	4.299723e-8
GO:0090031	positive regulation of steroid hormone biosynthetic process	8.845634e-8
GO:0070873	regulation of glycogen metabolic process	1.001354e-7
GO:2000273	positive regulation of receptor activity	1.837889e-7
GO:0071585	detoxification of cadmium ion	2.138967e-7
GO:0045653	negative regulation of megakaryocyte differentiation	3.064017e-7
GO:0042254	ribosome biogenesis	3.121290e-7
GO:0022027	interkinetic nuclear migration	3.508368e-7
GO:0065002	intracellular protein transmembrane transport	4.507341e-7
GO:0006364	rRNA processing	5.198339e-7
GO:0016072	rRNA metabolic process	5.228521e-7
GO:0006405	RNA export from nucleus	6.266424e-7
GO:0048075	positive regulation of eye pigmentation	7.910414e-7
GO:0031017	exocrine pancreas development	1.159487e-6
GO:0021506	anterior neuropore closure	1.286099e-6
GO:0006349	regulation of gene expression by genetic imprinting	1.678748e-6
GO:0035095	behavioral response to nicotine	2.159136e-6
GO:0042104	positive regulation of activated T cell proliferation	2.202717e-6
GO:0090281	negative regulation of calcium ion import	2.320005e-6
GO:0071584	negative regulation of zinc ion import	2.320005e-6
GO:0006779	porphyrin-containing compound biosynthetic process	2.946332e-6
GO:0032468	Golgi calcium ion homeostasis	3.498494e-6
GO:0032472	Golgi calcium ion transport	3.498494e-6
GO:0030026	cellular manganese ion homeostasis	3.498494e-6
GO:0060040	retinal bipolar neuron differentiation	5.526380e-6
GO:0019478	D-amino acid catabolic process	5.621570e-6
GO:0045725	positive regulation of glycogen biosynthetic process	6.219687e-6
GO:0035329	hippo signaling cascade	7.378938e-6
GO:0090305	nucleic acid phosphodiester bond hydrolysis	8.855570e-6
GO:0002115	store-operated calcium entry	1.010585e-5
GO:0016480	negative regulation of transcription from RNA polymerase III promoter	1.158608e-5
GO:0035090	maintenance of apical/basal cell polarity	1.222760e-5
GO:0046416	D-amino acid metabolic process	1.243085e-5
GO:0034660	ncRNA metabolic process	1.456745e-5
GO:0022613	ribonucleoprotein complex biogenesis	1.520080e-5
GO:0046105	thymidine biosynthetic process	1.771466e-5
GO:0034766	negative regulation of ion transmembrane transport	1.771466e-5
GO:0034080	CenH3-containing nucleosome assembly at centromere	1.779526e-5
GO:0070875	positive regulation of glycogen metabolic process	1.815171e-5
GO:0006361	transcription initiation from RNA polymerase I promoter	1.818650e-5
GO:0050983	deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase	1.864829e-5
GO:0003199	endocardial cushion to mesenchymal transition involved in heart valve formation	1.864829e-5
GO:0006013	mannose metabolic process	1.986925e-5
GO:0000387	spliceosomal snRNP assembly	1.991171e-5
GO:0048073	regulation of eye pigmentation	2.193691e-5
GO:0046006	regulation of activated T cell proliferation	2.229099e-5
GO:0071168	protein localization to chromatin	2.305995e-5
GO:0060084	synaptic transmission involved in micturition	2.374775e-5
GO:0006760	folic acid-containing compound metabolic process	2.845432e-5
GO:0043467	regulation of generation of precursor metabolites and energy	3.005216e-5
GO:0034241	positive regulation of macrophage fusion	3.059380e-5
GO:0031119	tRNA pseudouridine synthesis	3.059380e-5
GO:0006363	termination of RNA polymerase I transcription	3.282001e-5
GO:0046022	positive regulation of transcription from RNA polymerase II promoter during mitosis	3.409411e-5
GO:0006281	DNA repair	3.502963e-5
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	3.516267e-5
GO:0021623	oculomotor nerve formation	3.546262e-5
GO:0003409	optic cup structural organization	3.546262e-5
GO:0003404	optic vesicle morphogenesis	3.546262e-5
GO:0060160	negative regulation of dopamine receptor signaling pathway	3.728533e-5
GO:0006335	DNA replication-dependent nucleosome assembly	3.728533e-5
GO:2000077	negative regulation of type B pancreatic cell development	4.162488e-5
GO:0006545	glycine biosynthetic process	4.545347e-5
GO:0006308	DNA catabolic process	4.784061e-5
GO:0006289	nucleotide-excision repair	5.308363e-5
GO:0046886	positive regulation of hormone biosynthetic process	5.359958e-5
GO:0051647	nucleus localization	5.867626e-5
GO:2000466	negative regulation of glycogen (starch) synthase activity	6.165405e-5
GO:0070935	3'-UTR-mediated mRNA stabilization	6.563315e-5
GO:0006778	porphyrin-containing compound metabolic process	7.785746e-5
GO:0032581	ER-dependent peroxisome organization	8.041920e-5
GO:0085020	protein K6-linked ubiquitination	8.343123e-5
GO:0045652	regulation of megakaryocyte differentiation	9.956654e-5
GO:0007020	microtubule nucleation	9.998043e-5
GO:0019264	glycine biosynthetic process from serine	1.029065e-4
GO:0006260	DNA replication	1.045721e-4
GO:0050779	RNA destabilization	1.083638e-4
GO:0051793	medium-chain fatty acid catabolic process	1.123192e-4
GO:0031118	rRNA pseudouridine synthesis	1.123192e-4
GO:0031619	homologous chromosome orientation involved in meiotic metaphase I plate congression	1.123192e-4
GO:0032007	negative regulation of TOR signaling cascade	1.144958e-4
GO:0045358	negative regulation of interferon-beta biosynthetic process	1.145239e-4
GO:0010509	polyamine homeostasis	1.145239e-4
GO:0006427	histidyl-tRNA aminoacylation	1.145239e-4
GO:0010907	positive regulation of glucose metabolic process	1.171925e-4
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	1.452284e-4
GO:0031047	gene silencing by RNA	1.677016e-4
GO:0033119	negative regulation of RNA splicing	1.728430e-4
GO:0006390	transcription from mitochondrial promoter	1.765143e-4
GO:0010621	negative regulation of transcription by transcription factor localization	1.822709e-4
GO:0071281	cellular response to iron ion	1.825051e-4
GO:0006783	heme biosynthetic process	1.842327e-4
GO:0035166	post-embryonic hemopoiesis	1.906674e-4
GO:0006598	polyamine catabolic process	2.074211e-4
GO:0006359	regulation of transcription from RNA polymerase III promoter	2.092692e-4
GO:0032933	SREBP-mediated signaling pathway	2.326089e-4
GO:0016338	calcium-independent cell-cell adhesion	2.387269e-4
GO:0008216	spermidine metabolic process	2.576265e-4
GO:0031055	chromatin remodeling at centromere	2.676275e-4
GO:0035104	positive regulation of transcription via sterol regulatory element binding	2.680799e-4
GO:0034470	ncRNA processing	2.748182e-4
GO:0033013	tetrapyrrole metabolic process	2.881162e-4
GO:0001830	trophectodermal cell fate commitment	2.891424e-4
GO:0050720	interleukin-1 beta biosynthetic process	2.922661e-4
GO:0018009	N-terminal peptidyl-L-cysteine N-palmitoylation	2.922661e-4
GO:0061157	mRNA destabilization	3.057372e-4
GO:0010609	posttranscriptional regulation of gene expression by mRNA localization	3.057372e-4
GO:0002536	respiratory burst involved in inflammatory response	3.057372e-4
GO:0045047	protein targeting to ER	3.195977e-4
GO:2000378	negative regulation of reactive oxygen species metabolic process	3.318480e-4
GO:0021603	cranial nerve formation	3.464538e-4
GO:0072302	negative regulation of metanephric glomerular mesangial cell proliferation	3.496063e-4
GO:0061032	visceral serous pericardium development	3.496063e-4
GO:0043276	anoikis	3.496063e-4
GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	3.553616e-4
GO:0071843	cellular component biogenesis at cellular level	3.797940e-4
GO:0071169	establishment of protein localization to chromatin	3.867839e-4
GO:0030262	apoptotic nuclear change	3.997052e-4
GO:0042168	heme metabolic process	4.006047e-4
GO:0006228	UTP biosynthetic process	4.073914e-4
GO:0006183	GTP biosynthetic process	4.073914e-4
GO:0006165	nucleoside diphosphate phosphorylation	4.073914e-4
GO:0051168	nuclear export	4.124149e-4
GO:0002679	respiratory burst involved in defense response	4.141761e-4
GO:0046796	viral genome transport in host cell	4.277889e-4
GO:0000578	embryonic axis specification	4.345339e-4
GO:0006707	cholesterol catabolic process	4.365525e-4
GO:0051028	mRNA transport	4.525050e-4
GO:0071514	genetic imprinting	4.576284e-4
GO:0006544	glycine metabolic process	4.939548e-4
GO:0051313	attachment of spindle microtubules to chromosome	5.007617e-4
GO:0018206	peptidyl-methionine modification	5.334332e-4
GO:0006379	mRNA cleavage	5.382007e-4
GO:0021528	commissural neuron differentiation in spinal cord	5.432992e-4
GO:0048298	positive regulation of isotype switching to IgA isotypes	5.466784e-4
GO:0061011	hepatic duct development	5.557327e-4
GO:0006348	chromatin silencing at telomere	5.557327e-4
GO:0000718	nucleotide-excision repair, DNA damage removal	5.593957e-4
GO:0046015	regulation of transcription by glucose	5.959375e-4
GO:0010676	positive regulation of cellular carbohydrate metabolic process	5.979169e-4
GO:0090307	spindle assembly involved in mitosis	5.985330e-4
GO:0045199	maintenance of epithelial cell apical/basal polarity	6.276367e-4
GO:2000188	regulation of cholesterol homeostasis	6.276367e-4
GO:0015884	folic acid transport	6.489757e-4
GO:0006391	transcription initiation from mitochondrial promoter	6.634887e-4
GO:0002502	peptide antigen assembly with MHC class I protein complex	6.634887e-4
GO:0032288	myelin assembly	6.881166e-4
GO:0010266	response to vitamin B1	7.033008e-4
GO:0007194	negative regulation of adenylate cyclase activity	7.138989e-4
GO:0006290	pyrimidine dimer repair	7.437662e-4
GO:0000154	rRNA modification	7.437662e-4
GO:0031442	positive regulation of mRNA 3'-end processing	7.502687e-4
GO:0033239	negative regulation of cellular amine metabolic process	7.603723e-4
GO:0006398	histone mRNA 3'-end processing	7.604722e-4
GO:0001916	positive regulation of T cell mediated cytotoxicity	7.658570e-4
GO:0032392	DNA geometric change	7.713391e-4
GO:0007051	spindle organization	7.773542e-4
GO:0006481	C-terminal protein methylation	8.001092e-4
GO:0051350	negative regulation of lyase activity	8.061689e-4
GO:0043985	histone H4-R3 methylation	8.226360e-4
GO:0044319	wound healing, spreading of cells	8.277542e-4
GO:0042274	ribosomal small subunit biogenesis	8.289832e-4
GO:0006360	transcription from RNA polymerase I promoter	9.154188e-4
GO:0035088	establishment or maintenance of apical/basal cell polarity	9.273154e-4
GO:0045454	cell redox homeostasis	9.330295e-4
GO:0043089	positive regulation of Cdc42 GTPase activity	9.659111e-4
GO:0000720	pyrimidine dimer repair by nucleotide-excision repair	9.666050e-4
GO:0007354	zygotic determination of anterior/posterior axis, embryo	9.994955e-4
GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c	1.015758e-3
GO:0046939	nucleotide phosphorylation	1.054661e-3
GO:0035313	wound healing, spreading of epidermal cells	1.055164e-3
GO:0046426	negative regulation of JAK-STAT cascade	1.060273e-3
GO:0006362	transcription elongation from RNA polymerase I promoter	1.067278e-3
GO:0016598	protein arginylation	1.073411e-3
GO:0071934	thiamine transmembrane transport	1.073411e-3
GO:0006682	galactosylceramide biosynthetic process	1.073411e-3
GO:0009650	UV protection	1.084345e-3
GO:0006241	CTP biosynthetic process	1.101375e-3
GO:0042732	D-xylose metabolic process	1.120186e-3
GO:0070535	histone H2A K63-linked ubiquitination	1.120186e-3
GO:0010999	regulation of eIF2 alpha phosphorylation by heme	1.120186e-3
GO:0009589	detection of UV	1.120186e-3
GO:0071415	cellular response to purine-containing compound	1.163841e-3
GO:0046108	uridine metabolic process	1.163841e-3
GO:0010225	response to UV-C	1.164353e-3
GO:0016048	detection of temperature stimulus	1.216694e-3
GO:0006268	DNA unwinding involved in replication	1.219822e-3
GO:0006491	N-glycan processing	1.258986e-3
GO:0016973	poly(A)+ mRNA export from nucleus	1.266229e-3
GO:0032205	negative regulation of telomere maintenance	1.278825e-3
GO:0044258	intestinal lipid catabolic process	1.312987e-3
GO:0018350	protein esterification	1.312987e-3
GO:0002860	positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	1.423865e-3
GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway	1.546785e-3
GO:0070574	cadmium ion transmembrane transport	1.555995e-3
GO:0046655	folic acid metabolic process	1.586057e-3
GO:0016570	histone modification	1.637584e-3
GO:0032508	DNA duplex unwinding	1.639881e-3
GO:0048102	autophagic cell death	1.677319e-3
GO:0030237	female sex determination	1.690819e-3
GO:0030953	astral microtubule organization	1.749060e-3
GO:0018345	protein palmitoylation	1.775344e-3
GO:0051256	spindle midzone assembly involved in mitosis	1.784911e-3
GO:0010906	regulation of glucose metabolic process	1.786243e-3
GO:0008049	male courtship behavior	1.797859e-3
GO:0006479	protein methylation	1.808106e-3
GO:0060042	retina morphogenesis in camera-type eye	1.818668e-3
GO:0032239	regulation of nucleobase-containing compound transport	2.044188e-3
GO:0007193	inhibition of adenylate cyclase activity by G-protein signaling pathway	2.052378e-3
GO:0016191	synaptic vesicle uncoating	2.086093e-3
GO:0007100	mitotic centrosome separation	2.086093e-3
GO:0006284	base-excision repair	2.086851e-3
GO:0035873	lactate transmembrane transport	2.156427e-3
GO:0001302	replicative cell aging	2.196364e-3
GO:0040029	regulation of gene expression, epigenetic	2.206970e-3
GO:0016571	histone methylation	2.258734e-3
GO:0043255	regulation of carbohydrate biosynthetic process	2.259761e-3
GO:0071157	negative regulation of cell cycle arrest	2.283115e-3
GO:0007000	nucleolus organization	2.302948e-3
GO:0006283	transcription-coupled nucleotide-excision repair	2.306863e-3
GO:0006302	double-strand break repair	2.314089e-3
GO:0034723	DNA replication-dependent nucleosome organization	2.328961e-3
GO:0048733	sebaceous gland development	2.368384e-3
GO:0030718	germ-line stem cell maintenance	2.368384e-3
GO:0090141	positive regulation of mitochondrial fission	2.371635e-3
GO:0000089	mitotic metaphase	2.435091e-3
GO:0090230	regulation of centromere complex assembly	2.512120e-3
GO:0032352	positive regulation of hormone metabolic process	2.671021e-3
GO:0010944	negative regulation of transcription by competitive promoter binding	2.704522e-3
GO:0045014	negative regulation of transcription by glucose	2.723460e-3
GO:0010985	negative regulation of lipoprotein particle clearance	2.786151e-3
GO:0060455	negative regulation of gastric acid secretion	2.799065e-3
GO:0045656	negative regulation of monocyte differentiation	2.799065e-3
GO:0048050	post-embryonic eye morphogenesis	2.799065e-3
GO:0034587	piRNA metabolic process	2.825086e-3
GO:0046039	GTP metabolic process	2.854850e-3
GO:0008334	histone mRNA metabolic process	2.870319e-3
GO:0060998	regulation of dendritic spine development	2.896072e-3
GO:0031848	protection from non-homologous end joining at telomere	2.950774e-3
GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	2.950774e-3
GO:0009798	axis specification	2.987611e-3
GO:0010988	regulation of low-density lipoprotein particle clearance	3.008204e-3
GO:0044314	protein K27-linked ubiquitination	3.034044e-3
GO:0045792	negative regulation of cell size	3.043554e-3
GO:0060041	retina development in camera-type eye	3.134216e-3
GO:0003334	keratinocyte development	3.138838e-3
GO:0061002	negative regulation of dendritic spine morphogenesis	3.179827e-3
GO:0042558	pteridine-containing compound metabolic process	3.223832e-3
GO:0006984	ER-nucleus signaling pathway	3.279031e-3
GO:0030828	positive regulation of cGMP biosynthetic process	3.345507e-3
GO:0070979	protein K11-linked ubiquitination	3.474071e-3
GO:0016569	covalent chromatin modification	3.536091e-3
GO:0006529	asparagine biosynthetic process	3.587832e-3
GO:2000189	positive regulation of cholesterol homeostasis	3.610181e-3
GO:0090234	regulation of kinetochore assembly	3.633644e-3
GO:0090169	regulation of spindle assembly	3.633644e-3
GO:2000251	positive regulation of actin cytoskeleton reorganization	3.842228e-3
GO:0042255	ribosome assembly	3.873808e-3
GO:0034969	histone arginine methylation	3.879697e-3
GO:0009070	serine family amino acid biosynthetic process	3.889946e-3
GO:0071034	CUT catabolic process	3.990969e-3
GO:0042711	maternal behavior	3.995911e-3
GO:0071476	cellular hypotonic response	4.022257e-3
GO:0031268	pseudopodium organization	4.086112e-3
GO:0071307	cellular response to vitamin K	4.149650e-3
GO:0050904	diapedesis	4.149650e-3
GO:0048291	isotype switching to IgG isotypes	4.149650e-3
GO:0071403	cellular response to high density lipoprotein particle stimulus	4.149650e-3
GO:0071423	malate transmembrane transport	4.149650e-3
GO:0071448	cellular response to alkyl hydroperoxide	4.149650e-3
GO:0071315	cellular response to morphine	4.149650e-3
GO:0002842	positive regulation of T cell mediated immune response to tumor cell	4.149650e-3
GO:0002368	B cell cytokine production	4.149650e-3
GO:0031269	pseudopodium assembly	4.149650e-3
GO:0006756	AMP phosphorylation	4.149650e-3
GO:0014739	positive regulation of muscle hyperplasia	4.149650e-3
GO:0018364	peptidyl-glutamine methylation	4.149650e-3
GO:0015709	thiosulfate transport	4.149650e-3
GO:0070943	neutrophil mediated killing of symbiont cell	4.155657e-3
GO:0042218	1-aminocyclopropane-1-carboxylate biosynthetic process	4.232618e-3
GO:0043966	histone H3 acetylation	4.270398e-3
GO:0051545	negative regulation of elastin biosynthetic process	4.318908e-3
GO:0043543	protein acylation	4.349438e-3
GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	4.397962e-3
GO:0070946	neutrophil mediated killing of gram-positive bacterium	4.609669e-3
GO:0042766	nucleosome mobilization	4.609669e-3
GO:0060716	labyrinthine layer blood vessel development	4.792970e-3
GO:0051255	spindle midzone assembly	4.795312e-3
GO:0065001	specification of axis polarity	4.841141e-3
GO:0006600	creatine metabolic process	4.870926e-3
GO:0048149	behavioral response to ethanol	5.027700e-3
GO:0032525	somite rostral/caudal axis specification	5.071723e-3
GO:0046513	ceramide biosynthetic process	5.116171e-3
GO:2000971	negative regulation of detection of glucose	5.142496e-3
GO:2000976	regulation of transcription from RNA polymerase II promoter involved in detection of glucose	5.142496e-3
GO:0000433	negative regulation of transcription from RNA polymerase II promoter by glucose	5.142496e-3
GO:0035357	peroxisome proliferator activated receptor signaling pathway	5.211652e-3
GO:0010984	regulation of lipoprotein particle clearance	5.221644e-3
GO:0050689	negative regulation of defense response to virus by host	5.235658e-3
GO:0071539	protein localization to centrosome	5.388445e-3
GO:0007271	synaptic transmission, cholinergic	5.404911e-3
GO:0006386	termination of RNA polymerase III transcription	5.435969e-3
GO:0051131	chaperone-mediated protein complex assembly	5.435969e-3
GO:0006385	transcription elongation from RNA polymerase III promoter	5.435969e-3
GO:0000375	RNA splicing, via transesterification reactions	5.539248e-3
GO:0060060	post-embryonic retina morphogenesis in camera-type eye	5.550084e-3
GO:0034633	retinol transport	5.550084e-3
GO:0070172	positive regulation of tooth mineralization	5.600245e-3
GO:0000398	nuclear mRNA splicing, via spliceosome	5.601144e-3
GO:0006309	DNA fragmentation involved in apoptotic nuclear change	5.612112e-3
GO:0035461	vitamin transmembrane transport	5.637345e-3
GO:0006498	N-terminal protein lipidation	5.637345e-3
GO:0033132	negative regulation of glucokinase activity	5.641365e-3
GO:0000415	negative regulation of histone H3-K36 methylation	5.641365e-3
GO:0032864	activation of Cdc42 GTPase activity	5.641365e-3
GO:0008595	anterior/posterior axis specification, embryo	5.760154e-3
GO:0033314	mitotic cell cycle DNA replication checkpoint	5.787950e-3
GO:0043088	regulation of Cdc42 GTPase activity	5.885230e-3
GO:0016574	histone ubiquitination	6.003117e-3
GO:0046831	regulation of RNA export from nucleus	6.075569e-3
GO:2001076	positive regulation of metanephric ureteric bud development	6.237942e-3
GO:0007356	thorax and anterior abdomen determination	6.237942e-3
GO:0072301	regulation of metanephric glomerular mesangial cell proliferation	6.385268e-3
GO:0009148	pyrimidine nucleoside triphosphate biosynthetic process	6.456158e-3
GO:0009253	peptidoglycan catabolic process	6.500754e-3
GO:0015813	L-glutamate transport	6.548987e-3
GO:0051005	negative regulation of lipoprotein lipase activity	6.606766e-3
GO:0000723	telomere maintenance	6.620377e-3
GO:0048569	post-embryonic organ development	6.743610e-3
GO:0007090	regulation of S phase of mitotic cell cycle	6.803819e-3
GO:0048561	establishment of organ orientation	6.837221e-3
GO:0046078	dUMP metabolic process	6.837221e-3
GO:0019323	pentose catabolic process	6.837221e-3
GO:0032241	positive regulation of nucleobase-containing compound transport	6.837221e-3
GO:0051546	keratinocyte migration	6.890038e-3
GO:0070874	negative regulation of glycogen metabolic process	6.916479e-3
GO:0010701	positive regulation of norepinephrine secretion	7.234505e-3
GO:0016075	rRNA catabolic process	7.340417e-3
GO:0070170	regulation of tooth mineralization	7.439250e-3
GO:0060179	male mating behavior	7.471264e-3
GO:0032287	peripheral nervous system myelin maintenance	7.546353e-3
GO:0008292	acetylcholine biosynthetic process	7.546353e-3
GO:0001980	regulation of systemic arterial blood pressure by ischemic conditions	7.546353e-3
GO:0016233	telomere capping	7.738287e-3
GO:0009304	tRNA transcription	7.738287e-3
GO:0071469	cellular response to alkalinity	7.987421e-3
GO:2000009	negative regulation of protein localization at cell surface	7.987421e-3
GO:0001519	peptide amidation	7.987421e-3
GO:0046079	dUMP catabolic process	7.987421e-3
GO:0043456	regulation of pentose-phosphate shunt	7.987421e-3
GO:0031860	telomeric 3' overhang formation	7.987421e-3
GO:0005978	glycogen biosynthetic process	8.006860e-3
GO:0007029	endoplasmic reticulum organization	8.016484e-3
GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein	8.069485e-3
GO:0045719	negative regulation of glycogen biosynthetic process	8.086258e-3
GO:0006370	mRNA capping	8.148559e-3
GO:0048268	clathrin coat assembly	8.387220e-3
GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion	8.425411e-3
GO:0042524	negative regulation of tyrosine phosphorylation of Stat5 protein	8.425411e-3
GO:0006334	nucleosome assembly	8.462382e-3
GO:0051135	positive regulation of NK T cell activation	8.478129e-3
GO:0045556	positive regulation of TRAIL biosynthetic process	8.720904e-3
GO:0009451	RNA modification	8.827632e-3
GO:0090138	regulation of actin cytoskeleton organization by cell-cell adhesion	8.857735e-3
GO:0042998	positive regulation of Golgi to plasma membrane protein transport	8.857735e-3
GO:0035871	protein K11-linked deubiquitination	8.857735e-3
GO:0034699	response to luteinizing hormone stimulus	8.857735e-3
GO:0007009	plasma membrane organization	8.990128e-3
GO:0001705	ectoderm formation	9.248944e-3
GO:0050965	detection of temperature stimulus involved in sensory perception of pain	9.271410e-3
GO:0019254	carnitine metabolic process, CoA-linked	9.271410e-3
GO:0032383	regulation of intracellular cholesterol transport	9.271410e-3
GO:0009437	carnitine metabolic process	9.388695e-3
GO:0000959	mitochondrial RNA metabolic process	9.445627e-3
GO:0060421	positive regulation of heart growth	9.449377e-3
GO:0006109	regulation of carbohydrate metabolic process	9.509721e-3
GO:0043486	histone exchange	9.558424e-3
GO:0071816	tail-anchored membrane protein insertion into ER membrane	9.594640e-3
GO:0072659	protein localization in plasma membrane	9.634526e-3
GO:0002432	granuloma formation	9.737679e-3
GO:0006533	aspartate catabolic process	9.737679e-3
GO:0070972	protein localization in endoplasmic reticulum	9.949748e-3
GO:0043060	meiotic metaphase I plate congression	1.005319e-2
GO:0010900	negative regulation of phosphatidylcholine catabolic process	1.005319e-2
GO:0042506	tyrosine phosphorylation of Stat5 protein	1.006831e-2
GO:0048239	negative regulation of DNA recombination at telomere	1.011907e-2
GO:0006261	DNA-dependent DNA replication	1.034154e-2
GO:0033057	multicellular organismal reproductive behavior	1.042615e-2
GO:0014738	regulation of muscle hyperplasia	1.067987e-2
GO:0009132	nucleoside diphosphate metabolic process	1.094757e-2
GO:0016576	histone dephosphorylation	1.110525e-2
GO:0042520	positive regulation of tyrosine phosphorylation of Stat4 protein	1.123532e-2
GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase	1.123532e-2
GO:0060829	negative regulation of canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation	1.130856e-2
GO:0051791	medium-chain fatty acid metabolic process	1.130856e-2
GO:0071279	cellular response to cobalt ion	1.130856e-2
GO:0008616	queuosine biosynthetic process	1.130856e-2
GO:0010637	negative regulation of mitochondrial fusion	1.130856e-2
GO:0000354	cis assembly of pre-catalytic spliceosome	1.130856e-2
GO:0000236	mitotic prometaphase	1.134467e-2
GO:0050847	progesterone receptor signaling pathway	1.164702e-2
GO:0006659	phosphatidylserine biosynthetic process	1.170920e-2
GO:0001982	baroreceptor response to decreased systemic arterial blood pressure	1.172697e-2
GO:0000492	box C/D snoRNP assembly	1.172697e-2
GO:0018216	peptidyl-arginine methylation	1.189212e-2
GO:0051225	spindle assembly	1.190090e-2
GO:0048842	positive regulation of axon extension involved in axon guidance	1.234733e-2
GO:0021526	medial motor column neuron differentiation	1.234733e-2
GO:0060159	regulation of dopamine receptor signaling pathway	1.246547e-2
GO:0046586	regulation of calcium-dependent cell-cell adhesion	1.249751e-2
GO:0046929	negative regulation of neurotransmitter secretion	1.249751e-2
GO:0002839	positive regulation of immune response to tumor cell	1.267501e-2
GO:0006184	GTP catabolic process	1.270231e-2
GO:0090344	negative regulation of cell aging	1.289565e-2
GO:0010675	regulation of cellular carbohydrate metabolic process	1.294881e-2
GO:0016226	iron-sulfur cluster assembly	1.301450e-2
GO:0000080	G1 phase of mitotic cell cycle	1.306334e-2
GO:0000731	DNA synthesis involved in DNA repair	1.308490e-2
GO:0010971	positive regulation of G2/M transition of mitotic cell cycle	1.314595e-2
GO:0007004	telomere maintenance via telomerase	1.320417e-2
GO:0045329	carnitine biosynthetic process	1.321618e-2
GO:0051318	G1 phase	1.331950e-2
GO:0003407	neural retina development	1.343057e-2
GO:0002528	regulation of vascular permeability involved in acute inflammatory response	1.348445e-2
GO:0090232	positive regulation of spindle checkpoint	1.355663e-2
GO:0006564	L-serine biosynthetic process	1.355663e-2
GO:0045007	depurination	1.356613e-2
GO:0035356	cellular triglyceride homeostasis	1.356613e-2
GO:0008057	eye pigment granule organization	1.356613e-2
GO:0006400	tRNA modification	1.384386e-2
GO:0001832	blastocyst growth	1.394116e-2
GO:0060628	regulation of ER to Golgi vesicle-mediated transport	1.402097e-2
GO:0032259	methylation	1.407666e-2
GO:0009948	anterior/posterior axis specification	1.421637e-2
GO:0018205	peptidyl-lysine modification	1.460846e-2
GO:0006931	substrate-dependent cell migration, cell attachment to substrate	1.465245e-2
GO:2000573	positive regulation of DNA biosynthetic process	1.468836e-2
GO:0006383	transcription from RNA polymerase III promoter	1.477646e-2
GO:0035414	negative regulation of catenin import into nucleus	1.482977e-2
GO:0032289	central nervous system myelin formation	1.500808e-2
GO:0008291	acetylcholine metabolic process	1.500808e-2
GO:0006278	RNA-dependent DNA replication	1.509926e-2
GO:0042796	snRNA transcription from RNA polymerase III promoter	1.516573e-2
GO:0042941	D-alanine transport	1.516573e-2
GO:0043381	negative regulation of memory T cell differentiation	1.516573e-2
GO:0042795	snRNA transcription from RNA polymerase II promoter	1.516573e-2
GO:0033617	mitochondrial respiratory chain complex IV assembly	1.516573e-2
GO:0017196	N-terminal peptidyl-methionine acetylation	1.516573e-2
GO:0021764	amygdala development	1.516573e-2
GO:0015800	acidic amino acid transport	1.524887e-2
GO:0051323	metaphase	1.544507e-2
GO:0051457	maintenance of protein location in nucleus	1.546551e-2
GO:0051935	glutamate uptake involved in synaptic transmission	1.560678e-2
GO:0002149	hypochlorous acid biosynthetic process	1.560678e-2
GO:0046884	follicle-stimulating hormone secretion	1.581253e-2
GO:0032275	luteinizing hormone secretion	1.581253e-2
GO:0042703	menstruation	1.581253e-2
GO:0017004	cytochrome complex assembly	1.581253e-2
GO:0019101	female somatic sex determination	1.581253e-2
GO:0033522	histone H2A ubiquitination	1.585145e-2
GO:0043491	protein kinase B signaling cascade	1.591584e-2
GO:0046629	gamma-delta T cell activation	1.624017e-2
GO:0045212	neurotransmitter receptor biosynthetic process	1.624017e-2
GO:0042450	arginine biosynthetic process via ornithine	1.624017e-2
GO:0032223	negative regulation of synaptic transmission, cholinergic	1.624017e-2
GO:0045626	negative regulation of T-helper 1 cell differentiation	1.630958e-2
GO:0072124	regulation of glomerular mesangial cell proliferation	1.641152e-2
GO:0035771	interleukin-4-mediated signaling pathway	1.651072e-2
GO:0072166	posterior mesonephric tubule development	1.651072e-2
GO:0061001	regulation of dendritic spine morphogenesis	1.662599e-2
GO:0045655	regulation of monocyte differentiation	1.663627e-2
GO:0072348	sulfur compound transport	1.674565e-2
GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment	1.690025e-2
GO:0030187	melatonin biosynthetic process	1.690025e-2
GO:0071883	activation of MAPK activity by adrenergic receptor signaling pathway	1.690025e-2
GO:0021893	cerebral cortex GABAergic interneuron fate commitment	1.690025e-2
GO:0009452	RNA capping	1.698774e-2
GO:0045351	type I interferon biosynthetic process	1.701232e-2
GO:0050658	RNA transport	1.780819e-2
GO:0051586	positive regulation of dopamine uptake	1.780992e-2
GO:0048203	vesicle targeting, trans-Golgi to endosome	1.780992e-2
GO:0090140	regulation of mitochondrial fission	1.808730e-2
GO:0060689	cell differentiation involved in salivary gland development	1.808730e-2
GO:0060087	relaxation of vascular smooth muscle	1.808730e-2
GO:0002158	osteoclast proliferation	1.809938e-2

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0045922	negative regulation of fatty acid metabolic process	6.670440e-15
GO:0051005	negative regulation of lipoprotein lipase activity	2.397427e-14
GO:0045717	negative regulation of fatty acid biosynthetic process	2.519692e-14
GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	5.878056e-14
GO:0034382	chylomicron remnant clearance	5.690621e-13
GO:0010985	negative regulation of lipoprotein particle clearance	1.049267e-12
GO:0010984	regulation of lipoprotein particle clearance	1.209170e-11
GO:0060192	negative regulation of lipase activity	1.329202e-10
GO:0010987	negative regulation of high-density lipoprotein particle clearance	6.142273e-10
GO:0010897	negative regulation of triglyceride catabolic process	6.142273e-10
GO:0050995	negative regulation of lipid catabolic process	7.140022e-10
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	4.050817e-9
GO:0050823	peptide antigen stabilization	4.050817e-9
GO:0072302	negative regulation of metanephric glomerular mesangial cell proliferation	1.084136e-8
GO:2001076	positive regulation of metanephric ureteric bud development	1.084136e-8
GO:0007356	thorax and anterior abdomen determination	1.084136e-8
GO:0010900	negative regulation of phosphatidylcholine catabolic process	1.419432e-8
GO:0010982	regulation of high-density lipoprotein particle clearance	1.433251e-8
GO:0060620	regulation of cholesterol import	2.101168e-8
GO:0006302	double-strand break repair	3.830419e-8
GO:0010989	negative regulation of low-density lipoprotein particle clearance	4.904057e-8
GO:0060621	negative regulation of cholesterol import	7.299165e-8
GO:0006281	DNA repair	9.583888e-8
GO:0033627	cell adhesion mediated by integrin	1.240810e-7
GO:0035329	hippo signaling cascade	2.895742e-7
GO:0048261	negative regulation of receptor-mediated endocytosis	2.895742e-7
GO:0032375	negative regulation of cholesterol transport	3.406479e-7
GO:0033005	positive regulation of mast cell activation	5.223051e-7
GO:0043306	positive regulation of mast cell degranulation	5.914502e-7
GO:0090086	negative regulation of protein deubiquitination	6.077083e-7
GO:0021506	anterior neuropore closure	6.250828e-7
GO:0051055	negative regulation of lipid biosynthetic process	7.872140e-7
GO:0072125	negative regulation of glomerular mesangial cell proliferation	1.082361e-6
GO:0060696	regulation of phospholipid catabolic process	1.296821e-6
GO:0090084	negative regulation of inclusion body assembly	2.047768e-6
GO:0018924	mandelate metabolic process	2.423230e-6
GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	2.552837e-6
GO:0043302	positive regulation of leukocyte degranulation	2.646844e-6
GO:0033239	negative regulation of cellular amine metabolic process	2.961804e-6
GO:0061302	smooth muscle cell-matrix adhesion	3.356980e-6
GO:0072166	posterior mesonephric tubule development	3.718939e-6
GO:0035802	adrenal cortex formation	3.718939e-6
GO:0072301	regulation of metanephric glomerular mesangial cell proliferation	5.154764e-6
GO:0051004	regulation of lipoprotein lipase activity	5.400665e-6
GO:0031576	G2/M transition checkpoint	6.364833e-6
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	6.779873e-6
GO:0048259	regulation of receptor-mediated endocytosis	7.237602e-6
GO:0045833	negative regulation of lipid metabolic process	7.622014e-6
GO:0002483	antigen processing and presentation of endogenous peptide antigen	8.405956e-6
GO:0090083	regulation of inclusion body assembly	8.525016e-6
GO:0032717	negative regulation of interleukin-8 production	9.673635e-6
GO:0072124	regulation of glomerular mesangial cell proliferation	9.902684e-6
GO:0050713	negative regulation of interleukin-1 beta secretion	1.066819e-5
GO:0072278	metanephric comma-shaped body morphogenesis	1.104582e-5
GO:0072284	metanephric S-shaped body morphogenesis	1.104582e-5
GO:0090035	positive regulation of cellular chaperone-mediated protein complex assembly	1.145833e-5
GO:0000087	M phase of mitotic cell cycle	1.158138e-5
GO:0072015	glomerular visceral epithelial cell development	1.232555e-5
GO:0034447	very-low-density lipoprotein particle clearance	1.235703e-5
GO:0042304	regulation of fatty acid biosynthetic process	1.236718e-5
GO:0002536	respiratory burst involved in inflammatory response	1.255356e-5
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.255356e-5
GO:0061084	negative regulation of protein refolding	1.333043e-5
GO:0042998	positive regulation of Golgi to plasma membrane protein transport	2.149810e-5
GO:0017196	N-terminal peptidyl-methionine acetylation	2.149810e-5
GO:0016578	histone deubiquitination	2.309138e-5
GO:0033238	regulation of cellular amine metabolic process	2.312757e-5
GO:0048285	organelle fission	2.507058e-5
GO:0018095	protein polyglutamylation	3.178729e-5
GO:0006406	mRNA export from nucleus	3.628784e-5
GO:0000733	DNA strand renaturation	4.452813e-5
GO:0042273	ribosomal large subunit biogenesis	4.983671e-5
GO:0010903	negative regulation of very-low-density lipoprotein particle remodeling	5.128020e-5
GO:0043161	proteasomal ubiquitin-dependent protein catabolic process	5.296360e-5
GO:0007067	mitosis	5.375161e-5
GO:0051168	nuclear export	5.816911e-5
GO:0035850	epithelial cell differentiation involved in kidney development	6.524884e-5
GO:0072112	glomerular visceral epithelial cell differentiation	6.678736e-5
GO:0060923	cardiac muscle cell fate commitment	6.790328e-5
GO:0042254	ribosome biogenesis	7.018507e-5
GO:0006412	translation	7.383608e-5
GO:0000279	M phase	7.457346e-5
GO:0006391	transcription initiation from mitochondrial promoter	7.599772e-5
GO:0071156	regulation of cell cycle arrest	7.816223e-5
GO:0043457	regulation of cellular respiration	8.277457e-5
GO:0016559	peroxisome fission	8.292594e-5
GO:0071072	negative regulation of phospholipid biosynthetic process	8.444351e-5
GO:0071218	cellular response to misfolded protein	8.508280e-5
GO:0001830	trophectodermal cell fate commitment	8.696567e-5
GO:0050658	RNA transport	9.173339e-5
GO:0010498	proteasomal protein catabolic process	9.919561e-5
GO:0060674	placenta blood vessel development	1.052439e-4
GO:0060539	diaphragm development	1.052959e-4
GO:0070508	cholesterol import	1.128775e-4
GO:0006334	nucleosome assembly	1.158532e-4
GO:0031572	G2/M transition DNA damage checkpoint	1.313191e-4
GO:0090224	regulation of spindle organization	1.426310e-4
GO:0034629	cellular protein complex localization	1.493588e-4
GO:0006413	translational initiation	1.516459e-4
GO:0050711	negative regulation of interleukin-1 secretion	1.533308e-4
GO:0070845	polyubiquitinated misfolded protein transport	1.622830e-4
GO:0015746	citrate transport	1.622830e-4
GO:0035520	monoubiquitinated protein deubiquitination	1.668976e-4
GO:0006669	sphinganine-1-phosphate biosynthetic process	1.668976e-4
GO:0006405	RNA export from nucleus	1.669477e-4
GO:0045425	positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process	1.936016e-4
GO:0045401	positive regulation of interleukin-3 biosynthetic process	1.936016e-4
GO:0043304	regulation of mast cell degranulation	2.033290e-4
GO:0071071	regulation of phospholipid biosynthetic process	2.035257e-4
GO:0060911	cardiac cell fate commitment	2.100930e-4
GO:2000195	negative regulation of female gonad development	2.190377e-4
GO:0015820	leucine transport	2.190377e-4
GO:0000075	cell cycle checkpoint	2.256517e-4
GO:0035674	tricarboxylic acid transmembrane transport	2.370890e-4
GO:0006515	misfolded or incompletely synthesized protein catabolic process	2.397060e-4
GO:0016073	snRNA metabolic process	2.568339e-4
GO:0070979	protein K11-linked ubiquitination	2.718090e-4
GO:0090085	regulation of protein deubiquitination	2.984654e-4
GO:0045423	regulation of granulocyte macrophage colony-stimulating factor biosynthetic process	2.984654e-4
GO:0045964	positive regulation of dopamine metabolic process	3.169383e-4
GO:0006913	nucleocytoplasmic transport	3.426718e-4
GO:0010944	negative regulation of transcription by competitive promoter binding	3.593498e-4
GO:0065004	protein-DNA complex assembly	3.928241e-4
GO:0090042	tubulin deacetylation	3.970679e-4
GO:0070846	Hsp90 deacetylation	3.970679e-4
GO:0001579	medium-chain fatty acid transport	3.970679e-4
GO:0006844	acyl carnitine transport	3.970679e-4
GO:0015761	mannose transport	3.970679e-4
GO:0031503	protein complex localization	4.154208e-4
GO:0032328	alanine transport	4.314577e-4
GO:0002309	T cell proliferation involved in immune response	4.625377e-4
GO:0032784	regulation of transcription elongation, DNA-dependent	4.714450e-4
GO:0090343	positive regulation of cell aging	5.420111e-4
GO:0071824	protein-DNA complex subunit organization	5.489054e-4
GO:0006403	RNA localization	5.497028e-4
GO:0034728	nucleosome organization	5.574032e-4
GO:0045064	T-helper 2 cell differentiation	5.594418e-4
GO:0006235	dTTP biosynthetic process	5.594418e-4
GO:0032218	riboflavin transport	5.594418e-4
GO:0042256	mature ribosome assembly	5.599798e-4
GO:2000194	regulation of female gonad development	5.918237e-4
GO:0010310	regulation of hydrogen peroxide metabolic process	5.918237e-4
GO:0005978	glycogen biosynthetic process	6.026684e-4
GO:0065002	intracellular protein transmembrane transport	6.073673e-4
GO:0042942	D-serine transport	6.073673e-4
GO:0033006	regulation of mast cell activation involved in immune response	6.309038e-4
GO:0031584	activation of phospholipase D activity	6.566912e-4
GO:0021933	radial glia guided migration of cerebellar granule cell	7.164649e-4
GO:0007059	chromosome segregation	7.170319e-4
GO:0007141	male meiosis I	7.217267e-4
GO:0016180	snRNA processing	7.217267e-4
GO:0060712	spongiotrophoblast layer development	8.246333e-4
GO:0051169	nuclear transport	8.411409e-4
GO:0045806	negative regulation of endocytosis	8.427892e-4
GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter	9.413706e-4
GO:0006695	cholesterol biosynthetic process	9.507100e-4
GO:0051028	mRNA transport	9.670865e-4
GO:0006011	UDP-glucose metabolic process	9.844176e-4
GO:0018206	peptidyl-methionine modification	9.844176e-4
GO:0072500	negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor	1.025339e-3
GO:2000522	positive regulation of immunological synapse formation	1.025339e-3
GO:0046967	cytosol to ER transport	1.025339e-3
GO:0019060	intracellular transport of viral proteins in host cell	1.025339e-3
GO:0015724	formate transport	1.025339e-3
GO:0042851	L-alanine metabolic process	1.025339e-3
GO:0043366	beta selection	1.068526e-3
GO:0050689	negative regulation of defense response to virus by host	1.152617e-3
GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity	1.152617e-3
GO:0003241	growth involved in heart morphogenesis	1.152617e-3
GO:0046587	positive regulation of calcium-dependent cell-cell adhesion	1.152617e-3
GO:0022417	protein maturation by protein folding	1.152617e-3
GO:0018192	enzyme active site formation via L-cysteine persulfide	1.152617e-3
GO:0010896	regulation of triglyceride catabolic process	1.161867e-3
GO:0006259	DNA metabolic process	1.212605e-3
GO:0010972	negative regulation of G2/M transition of mitotic cell cycle	1.213327e-3
GO:0001935	endothelial cell proliferation	1.255204e-3
GO:0031497	chromatin assembly	1.300644e-3
GO:0006668	sphinganine-1-phosphate metabolic process	1.309375e-3
GO:0072215	regulation of metanephros development	1.469198e-3
GO:0007051	spindle organization	1.593515e-3
GO:0048025	negative regulation of nuclear mRNA splicing, via spliceosome	1.623399e-3
GO:0032786	positive regulation of transcription elongation, DNA-dependent	1.623399e-3
GO:0000959	mitochondrial RNA metabolic process	1.706943e-3
GO:0009148	pyrimidine nucleoside triphosphate biosynthetic process	1.711042e-3
GO:0007249	I-kappaB kinase/NF-kappaB cascade	1.747735e-3
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	1.773409e-3
GO:0071103	DNA conformation change	1.783271e-3
GO:0051208	sequestering of calcium ion	1.837309e-3
GO:0045358	negative regulation of interferon-beta biosynthetic process	1.837309e-3
GO:0019047	provirus integration	1.837309e-3
GO:0035313	wound healing, spreading of epidermal cells	1.864881e-3
GO:0002886	regulation of myeloid leukocyte mediated immunity	1.869470e-3
GO:0072272	proximal/distal pattern formation involved in metanephric nephron development	1.898640e-3
GO:0007406	negative regulation of neuroblast proliferation	1.915610e-3
GO:0006983	ER overload response	1.967159e-3
GO:0051292	nuclear pore complex assembly	1.979007e-3
GO:0090398	cellular senescence	1.999611e-3
GO:0031129	inductive cell-cell signaling	2.144912e-3
GO:0071104	response to interleukin-9	2.207714e-3
GO:0019348	dolichol metabolic process	2.239998e-3
GO:0050994	regulation of lipid catabolic process	2.297020e-3
GO:0001780	neutrophil homeostasis	2.350852e-3
GO:0032060	bleb assembly	2.365263e-3
GO:0038007	netrin-activated signaling pathway	2.397244e-3
GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway	2.397244e-3
GO:0021623	oculomotor nerve formation	2.397244e-3
GO:0003404	optic vesicle morphogenesis	2.397244e-3
GO:0003409	optic cup structural organization	2.397244e-3
GO:0006307	DNA dealkylation involved in DNA repair	2.695511e-3
GO:0051301	cell division	2.709844e-3
GO:0046984	regulation of hemoglobin biosynthetic process	2.899179e-3
GO:0010508	positive regulation of autophagy	2.952552e-3
GO:0006333	chromatin assembly or disassembly	3.007929e-3
GO:0042996	regulation of Golgi to plasma membrane protein transport	3.074624e-3
GO:0071422	succinate transmembrane transport	3.074624e-3
GO:0007144	female meiosis I	3.074624e-3
GO:0060580	ventral spinal cord interneuron fate determination	3.113505e-3
GO:0070535	histone H2A K63-linked ubiquitination	3.113505e-3
GO:0030150	protein import into mitochondrial matrix	3.113505e-3
GO:0018125	peptidyl-cysteine methylation	3.113505e-3
GO:0003327	type B pancreatic cell fate commitment	3.113505e-3
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	3.149268e-3
GO:0071281	cellular response to iron ion	3.270768e-3
GO:0070537	histone H2A K63-linked deubiquitination	3.270768e-3
GO:0060421	positive regulation of heart growth	3.345755e-3
GO:0042026	protein refolding	3.487283e-3
GO:0046881	positive regulation of follicle-stimulating hormone secretion	3.728470e-3
GO:0003329	pancreatic PP cell fate commitment	3.728470e-3
GO:0003326	pancreatic A cell fate commitment	3.728470e-3
GO:0007266	Rho protein signal transduction	3.753165e-3
GO:0030913	paranodal junction assembly	3.808037e-3
GO:0000910	cytokinesis	3.877210e-3
GO:0006323	DNA packaging	3.968027e-3
GO:0007354	zygotic determination of anterior/posterior axis, embryo	4.018348e-3
GO:0090234	regulation of kinetochore assembly	4.130643e-3
GO:0090169	regulation of spindle assembly	4.130643e-3
GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity	4.185640e-3
GO:0048178	negative regulation of hepatocyte growth factor biosynthetic process	4.185640e-3
GO:0042840	D-glucuronate catabolic process	4.237711e-3
GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	4.328334e-3
GO:0015827	tryptophan transport	4.332343e-3
GO:0006177	GMP biosynthetic process	4.332343e-3
GO:0000448	cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	4.379504e-3
GO:0035522	monoubiquitinated histone H2A deubiquitination	4.379504e-3
GO:0043048	dolichyl monophosphate biosynthetic process	4.379504e-3
GO:0035356	cellular triglyceride homeostasis	4.379504e-3
GO:0032329	serine transport	4.384142e-3
GO:0000077	DNA damage checkpoint	4.424673e-3
GO:0009147	pyrimidine nucleoside triphosphate metabolic process	4.600771e-3
GO:0022614	membrane to membrane docking	4.648010e-3
GO:0006906	vesicle fusion	4.677138e-3
GO:0090403	oxidative stress-induced premature senescence	4.762457e-3
GO:0022613	ribonucleoprotein complex biogenesis	4.953441e-3
GO:0034111	negative regulation of homotypic cell-cell adhesion	5.363214e-3
GO:0009299	mRNA transcription	5.403228e-3
GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	5.403228e-3
GO:0051303	establishment of chromosome localization	5.557742e-3
GO:0044319	wound healing, spreading of cells	5.557742e-3
GO:0006013	mannose metabolic process	5.557742e-3
GO:2000015	regulation of determination of dorsal identity	5.608157e-3
GO:0007034	vacuolar transport	5.700305e-3
GO:0046931	pore complex assembly	5.781048e-3
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	5.810235e-3
GO:0010107	potassium ion import	5.842736e-3
GO:0006837	serotonin transport	5.931832e-3
GO:0015677	copper ion import	5.942506e-3
GO:0060003	copper ion export	5.942506e-3
GO:0002541	activation of plasma proteins involved in acute inflammatory response	5.942506e-3
GO:0005980	glycogen catabolic process	6.052670e-3
GO:0070389	chaperone cofactor-dependent protein refolding	6.115556e-3
GO:0006999	nuclear pore organization	6.115556e-3
GO:2000036	regulation of stem cell maintenance	6.276951e-3
GO:0009083	branched chain family amino acid catabolic process	6.402379e-3
GO:0000080	G1 phase of mitotic cell cycle	6.590289e-3
GO:0002740	negative regulation of cytokine secretion involved in immune response	6.606238e-3
GO:0031398	positive regulation of protein ubiquitination	6.715684e-3
GO:0001824	blastocyst development	6.817883e-3
GO:0031570	DNA integrity checkpoint	6.875585e-3
GO:0001832	blastocyst growth	6.986770e-3
GO:0070935	3'-UTR-mediated mRNA stabilization	7.035478e-3
GO:0035511	oxidative DNA demethylation	7.172731e-3
GO:0016973	poly(A)+ mRNA export from nucleus	7.172731e-3
GO:0060554	induction of necroptosis of activated-T cells	7.218663e-3
GO:2000016	negative regulation of determination of dorsal identity	7.218663e-3
GO:0048203	vesicle targeting, trans-Golgi to endosome	7.218663e-3
GO:0006178	guanine salvage	7.218663e-3
GO:0046038	GMP catabolic process	7.218663e-3
GO:0032263	GMP salvage	7.218663e-3
GO:0032264	IMP salvage	7.218663e-3
GO:0032099	negative regulation of appetite	7.251017e-3
GO:0008635	activation of caspase activity by cytochrome c	7.350597e-3
GO:0001820	serotonin secretion	7.373304e-3
GO:0070172	positive regulation of tooth mineralization	7.508288e-3
GO:0015931	nucleobase-containing compound transport	7.524279e-3
GO:0021997	neural plate axis specification	7.604513e-3
GO:0060272	embryonic skeletal joint morphogenesis	7.669700e-3
GO:0016226	iron-sulfur cluster assembly	7.734374e-3
GO:0035552	oxidative single-stranded DNA demethylation	7.737757e-3
GO:0060040	retinal bipolar neuron differentiation	7.737757e-3
GO:0001732	formation of translation initiation complex	7.737757e-3
GO:0032092	positive regulation of protein binding	7.782157e-3
GO:0042732	D-xylose metabolic process	7.798950e-3
GO:0071158	positive regulation of cell cycle arrest	7.968384e-3
GO:0060017	parathyroid gland development	8.084722e-3
GO:0006517	protein deglycosylation	8.125781e-3
GO:0034276	kynurenic acid biosynthetic process	8.125781e-3
GO:0034725	DNA replication-dependent nucleosome disassembly	8.125781e-3
GO:0035481	positive regulation of Notch signaling pathway involved in heart induction	8.125781e-3
GO:0003259	cardioblast anterior-lateral migration	8.125781e-3
GO:0060975	cardioblast migration to the midline involved in heart field formation	8.125781e-3
GO:0002159	desmosome assembly	8.125781e-3
GO:0003236	sinus venosus morphogenesis	8.125781e-3
GO:0002534	cytokine production involved in inflammatory response	8.125781e-3
GO:0000027	ribosomal large subunit assembly	8.125781e-3
GO:0003210	cardiac atrium formation	8.125781e-3
GO:0002561	basophil degranulation	8.125781e-3
GO:0043300	regulation of leukocyte degranulation	8.230430e-3
GO:0071882	activation of phospholipase C activity by adrenergic receptor signaling pathway	8.253177e-3
GO:0071881	inhibition of adenylate cyclase activity by adrenergic receptor signaling pathway	8.253177e-3
GO:0003418	growth plate cartilage chondrocyte differentiation	8.253177e-3
GO:0070625	zymogen granule exocytosis	8.253177e-3
GO:0071843	cellular component biogenesis at cellular level	8.381710e-3
GO:0032924	activin receptor signaling pathway	8.466962e-3
GO:0090399	replicative senescence	8.540707e-3
GO:0030325	adrenal gland development	8.564121e-3
GO:0032096	negative regulation of response to food	8.572731e-3
GO:0032369	negative regulation of lipid transport	8.623483e-3
GO:0061025	membrane fusion	9.001382e-3
GO:0005997	xylulose metabolic process	9.087735e-3
GO:0000492	box C/D snoRNP assembly	9.087735e-3
GO:0009303	rRNA transcription	9.093788e-3
GO:0031954	positive regulation of protein autophosphorylation	9.152255e-3
GO:0051340	regulation of ligase activity	9.515406e-3
GO:0035136	forelimb morphogenesis	9.589081e-3
GO:0090342	regulation of cell aging	9.887149e-3
GO:0009081	branched chain family amino acid metabolic process	9.964208e-3
GO:0043103	hypoxanthine salvage	1.006648e-2
GO:0032261	purine nucleotide salvage	1.006648e-2
GO:0050935	iridophore differentiation	1.007761e-2
GO:0085020	protein K6-linked ubiquitination	1.007761e-2
GO:0048937	lateral line nerve glial cell development	1.007761e-2
GO:0010512	negative regulation of phosphatidylinositol biosynthetic process	1.007761e-2
GO:0033299	secretion of lysosomal enzymes	1.007761e-2
GO:0035425	autocrine signaling	1.007761e-2
GO:0051318	G1 phase	1.012626e-2
GO:0006610	ribosomal protein import into nucleus	1.038211e-2
GO:0060356	leucine import	1.042771e-2
GO:0035625	epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway	1.042771e-2
GO:0060236	regulation of mitotic spindle organization	1.042771e-2
GO:0006364	rRNA processing	1.077132e-2
GO:0010901	regulation of very-low-density lipoprotein particle remodeling	1.105993e-2
GO:0072422	signal transduction involved in DNA damage checkpoint	1.124716e-2
GO:0002268	follicular dendritic cell differentiation	1.132178e-2
GO:0072074	kidney mesenchyme development	1.134700e-2
GO:0034553	mitochondrial respiratory chain complex II assembly	1.156759e-2
GO:0046185	aldehyde catabolic process	1.156759e-2
GO:0034509	centromeric core chromatin assembly	1.156759e-2
GO:0003127	detection of nodal flow	1.156759e-2
GO:0031081	nuclear pore distribution	1.156759e-2
GO:0034080	CenH3-containing nucleosome assembly at centromere	1.156759e-2
GO:0003163	sinoatrial node development	1.162677e-2
GO:0072498	embryonic skeletal joint development	1.172578e-2
GO:2000020	positive regulation of male gonad development	1.179752e-2
GO:0007521	muscle cell fate determination	1.198790e-2
GO:0060039	pericardium development	1.220515e-2
GO:0072075	metanephric mesenchyme development	1.249579e-2
GO:0032488	Cdc42 protein signal transduction	1.274494e-2
GO:0006390	transcription from mitochondrial promoter	1.283915e-2
GO:0072268	pattern specification involved in metanephros development	1.292434e-2
GO:0070366	regulation of hepatocyte differentiation	1.292434e-2
GO:0032916	positive regulation of transforming growth factor beta3 production	1.292434e-2
GO:0046985	positive regulation of hemoglobin biosynthetic process	1.329691e-2
GO:0043973	histone H3-K4 acetylation	1.329691e-2
GO:0045415	negative regulation of interleukin-8 biosynthetic process	1.329691e-2
GO:0035269	protein O-linked mannosylation	1.329691e-2
GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery	1.329691e-2
GO:0032049	cardiolipin biosynthetic process	1.356619e-2
GO:2000383	regulation of ectoderm development	1.356619e-2
GO:0007172	signal complex assembly	1.356619e-2
GO:0051865	protein autoubiquitination	1.366715e-2
GO:0060683	regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling	1.396680e-2
GO:0045347	negative regulation of MHC class II biosynthetic process	1.396981e-2
GO:0070243	regulation of thymocyte apoptosis	1.419658e-2
GO:0000726	non-recombinational repair	1.424173e-2
GO:0002730	regulation of dendritic cell cytokine production	1.429864e-2
GO:0042664	negative regulation of endodermal cell fate specification	1.429864e-2
GO:0048313	Golgi inheritance	1.429864e-2
GO:0014063	negative regulation of serotonin secretion	1.429864e-2
GO:0040038	polar body extrusion after meiotic divisions	1.536862e-2
GO:0045769	negative regulation of asymmetric cell division	1.536862e-2
GO:0042941	D-alanine transport	1.536862e-2
GO:0017187	peptidyl-glutamic acid carboxylation	1.536862e-2
GO:0007057	spindle assembly involved in female meiosis I	1.536862e-2
GO:0009443	pyridoxal 5'-phosphate salvage	1.536862e-2
GO:0016482	cytoplasmic transport	1.536862e-2
GO:0032446	protein modification by small protein conjugation	1.538294e-2
GO:0030259	lipid glycosylation	1.549042e-2
GO:0035115	embryonic forelimb morphogenesis	1.554410e-2
GO:0003218	cardiac left ventricle formation	1.559444e-2
GO:0002031	G-protein coupled receptor internalization	1.559444e-2
GO:0033700	phospholipid efflux	1.602148e-2
GO:0035865	cellular response to potassium ion	1.651041e-2
GO:0035105	sterol regulatory element binding protein import into nucleus	1.651041e-2
GO:0045575	basophil activation	1.651041e-2
GO:0046814	virion attachment, binding of host cell surface coreceptor	1.651041e-2
GO:0060816	random inactivation of X chromosome	1.651041e-2
GO:0051790	short-chain fatty acid biosynthetic process	1.651041e-2
GO:0034651	cortisol biosynthetic process	1.651041e-2
GO:0034241	positive regulation of macrophage fusion	1.651041e-2
GO:0009786	regulation of asymmetric cell division	1.651041e-2
GO:0006256	UDP catabolic process	1.651041e-2
GO:0014853	regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction	1.651041e-2
GO:0019064	viral envelope fusion with host membrane	1.651041e-2
GO:0031468	nuclear envelope reassembly	1.651041e-2
GO:0030208	dermatan sulfate biosynthetic process	1.651041e-2
GO:0003430	growth plate cartilage chondrocyte growth	1.651041e-2
GO:0002262	myeloid cell homeostasis	1.678977e-2
GO:0042069	regulation of catecholamine metabolic process	1.679880e-2
GO:0021846	cell proliferation in forebrain	1.692265e-2
GO:0060921	sinoatrial node cell differentiation	1.696876e-2
GO:0048014	Tie receptor signaling pathway	1.696876e-2
GO:0071544	diphosphoinositol polyphosphate catabolic process	1.747856e-2
GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	1.747856e-2
GO:0090045	positive regulation of deacetylase activity	1.747856e-2
GO:0043031	negative regulation of macrophage activation	1.747856e-2
GO:0006507	GPI anchor release	1.747856e-2
GO:0042789	mRNA transcription from RNA polymerase II promoter	1.747856e-2
GO:0016126	sterol biosynthetic process	1.751306e-2
GO:0007076	mitotic chromosome condensation	1.752288e-2
GO:0006366	transcription from RNA polymerase II promoter	1.765480e-2
GO:0046939	nucleotide phosphorylation	1.772414e-2
GO:0006868	glutamine transport	1.780220e-2
GO:0045739	positive regulation of DNA repair	1.809171e-2
GO:0090161	Golgi ribbon formation	1.832673e-2
GO:0051639	actin filament network formation	1.832673e-2
GO:0009211	pyrimidine deoxyribonucleoside triphosphate metabolic process	1.832673e-2
GO:0046882	negative regulation of follicle-stimulating hormone secretion	1.832673e-2
GO:0051342	regulation of cyclic-nucleotide phosphodiesterase activity	1.832673e-2
GO:0006626	protein targeting to mitochondrion	1.848722e-2
GO:0060375	regulation of mast cell differentiation	1.872941e-2
GO:0001829	trophectodermal cell differentiation	1.875794e-2
GO:0060547	negative regulation of necrotic cell death	1.878025e-2
GO:0005981	regulation of glycogen catabolic process	1.881804e-2
GO:0035928	rRNA import into mitochondrion	1.886027e-2
GO:0018200	peptidyl-glutamic acid modification	1.910870e-2
GO:0007182	common-partner SMAD protein phosphorylation	1.910870e-2
GO:0033119	negative regulation of RNA splicing	1.917326e-2
GO:0002326	B cell lineage commitment	1.917326e-2
GO:0048284	organelle fusion	1.941243e-2
GO:0060347	heart trabecula formation	1.983979e-2
GO:0033364	mast cell secretory granule organization	2.017610e-2
GO:0016584	nucleosome positioning	2.017610e-2
GO:0010511	regulation of phosphatidylinositol biosynthetic process	2.038889e-2
GO:0017148	negative regulation of translation	2.088809e-2
GO:0035434	copper ion transmembrane transport	2.133550e-2
GO:0035510	DNA dealkylation	2.180105e-2
GO:0090209	negative regulation of triglyceride metabolic process	2.180105e-2
GO:0007566	embryo implantation	2.208247e-2
GO:0006944	cellular membrane fusion	2.223571e-2
GO:0010564	regulation of cell cycle process	2.238526e-2
GO:0033344	cholesterol efflux	2.248164e-2
GO:0034048	negative regulation of protein phosphatase type 2A activity	2.272614e-2
GO:0070093	negative regulation of glucagon secretion	2.272614e-2
GO:0032185	septin cytoskeleton organization	2.272614e-2
GO:0033566	gamma-tubulin complex localization	2.272614e-2
GO:0015680	intracellular copper ion transport	2.272614e-2
GO:0033631	cell-cell adhesion mediated by integrin	2.287214e-2
GO:0033025	regulation of mast cell apoptosis	2.287214e-2
GO:0007168	receptor guanylyl cyclase signaling pathway	2.287214e-2
GO:0061098	positive regulation of protein tyrosine kinase activity	2.355693e-2
GO:0043173	nucleotide salvage	2.359062e-2
GO:0072086	specification of loop of Henle identity	2.382188e-2
GO:0006511	ubiquitin-dependent protein catabolic process	2.385211e-2
GO:0043632	modification-dependent macromolecule catabolic process	2.430020e-2
GO:2000018	regulation of male gonad development	2.446271e-2
GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway	2.460111e-2
GO:0000089	mitotic metaphase	2.486333e-2
GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	2.486333e-2
GO:0000729	DNA double-strand break processing	2.486333e-2
GO:0071711	basement membrane organization	2.492344e-2
GO:0009082	branched chain family amino acid biosynthetic process	2.492344e-2
GO:0051029	rRNA transport	2.492344e-2
GO:0033572	transferrin transport	2.516926e-2
GO:0001843	neural tube closure	2.518341e-2
GO:0009880	embryonic pattern specification	2.525752e-2
GO:0006282	regulation of DNA repair	2.536109e-2
GO:2000173	negative regulation of branching morphogenesis of a nerve	2.556431e-2
GO:0050655	dermatan sulfate proteoglycan metabolic process	2.556431e-2
GO:0016557	peroxisome membrane biogenesis	2.556431e-2
GO:0014842	regulation of satellite cell proliferation	2.556431e-2
GO:0045601	regulation of endothelial cell differentiation	2.559859e-2
GO:0060613	fat pad development	2.584726e-2
GO:0006303	double-strand break repair via nonhomologous end joining	2.584726e-2
GO:0016072	rRNA metabolic process	2.659413e-2
GO:0032910	regulation of transforming growth factor beta3 production	2.659528e-2
GO:0050685	positive regulation of mRNA processing	2.663598e-2
GO:0016567	protein ubiquitination	2.665799e-2
GO:0061146	Peyer's patch morphogenesis	2.676922e-2
GO:0051545	negative regulation of elastin biosynthetic process	2.676922e-2
GO:0007495	visceral mesoderm-endoderm interaction involved in midgut development	2.676922e-2