Novel motif:122

name:	motif122_TACAAYGGM

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0070252	actin-mediated cell contraction	8.380999e-18
GO:0030049	muscle filament sliding	3.595039e-17
GO:0002376	immune system process	2.173312e-16
GO:0030048	actin filament-based movement	3.968302e-15
GO:0006955	immune response	7.314533e-15
GO:0045214	sarcomere organization	7.484727e-14
GO:0046491	L-methylmalonyl-CoA metabolic process	1.636966e-11
GO:0001932	regulation of protein phosphorylation	2.159873e-11
GO:0006952	defense response	2.997879e-11
GO:0042325	regulation of phosphorylation	3.716482e-11
GO:0006928	cellular component movement	9.770142e-11
GO:0051592	response to calcium ion	1.914141e-10
GO:0030240	skeletal muscle thin filament assembly	2.508155e-10
GO:0019220	regulation of phosphate metabolic process	4.098937e-10
GO:0031399	regulation of protein modification process	5.371426e-10
GO:0001775	cell activation	5.554101e-10
GO:0010033	response to organic substance	8.837697e-10
GO:0002576	platelet degranulation	1.169462e-9
GO:0045666	positive regulation of neuron differentiation	1.459989e-9
GO:0045087	innate immune response	1.533479e-9
GO:0043549	regulation of kinase activity	2.289385e-9
GO:0042127	regulation of cell proliferation	3.127773e-9
GO:0051338	regulation of transferase activity	4.427572e-9
GO:0008285	negative regulation of cell proliferation	4.702866e-9
GO:0006950	response to stress	5.460569e-9
GO:0042221	response to chemical stimulus	7.571186e-9
GO:0010627	regulation of intracellular protein kinase cascade	8.854415e-9
GO:0009966	regulation of signal transduction	9.175220e-9
GO:0002696	positive regulation of leukocyte activation	1.102506e-8
GO:0048387	negative regulation of retinoic acid receptor signaling pathway	1.616028e-8
GO:0045859	regulation of protein kinase activity	1.636210e-8
GO:0030239	myofibril assembly	1.663547e-8
GO:0002694	regulation of leukocyte activation	2.296341e-8
GO:0050863	regulation of T cell activation	2.452695e-8
GO:0048385	regulation of retinoic acid receptor signaling pathway	3.253394e-8
GO:0014866	skeletal myofibril assembly	3.446986e-8
GO:0006941	striated muscle contraction	3.784998e-8
GO:0045321	leukocyte activation	5.384837e-8
GO:0018149	peptide cross-linking	5.611937e-8
GO:0051239	regulation of multicellular organismal process	5.787425e-8
GO:0071841	cellular component organization or biogenesis at cellular level	5.971443e-8
GO:0050867	positive regulation of cell activation	6.794905e-8
GO:0006887	exocytosis	8.841677e-8
GO:0051249	regulation of lymphocyte activation	9.931649e-8
GO:0060416	response to growth hormone stimulus	1.018226e-7
GO:0051247	positive regulation of protein metabolic process	1.070069e-7
GO:0050896	response to stimulus	1.101351e-7
GO:0050865	regulation of cell activation	1.156985e-7
GO:0032880	regulation of protein localization	1.225394e-7
GO:0007522	visceral muscle development	1.421777e-7
GO:0022408	negative regulation of cell-cell adhesion	1.679710e-7
GO:0090092	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	1.920920e-7
GO:0010927	cellular component assembly involved in morphogenesis	1.979925e-7
GO:0070201	regulation of establishment of protein localization	2.093481e-7
GO:0032543	mitochondrial translation	2.492172e-7
GO:0002682	regulation of immune system process	2.674455e-7
GO:0050672	negative regulation of lymphocyte proliferation	3.093880e-7
GO:0051222	positive regulation of protein transport	3.769172e-7
GO:0048513	organ development	3.790383e-7
GO:0032501	multicellular organismal process	3.852225e-7
GO:0042327	positive regulation of phosphorylation	4.364485e-7
GO:0050870	positive regulation of T cell activation	4.542842e-7
GO:0032270	positive regulation of cellular protein metabolic process	4.914002e-7
GO:0050790	regulation of catalytic activity	5.146993e-7
GO:0046034	ATP metabolic process	5.386284e-7
GO:2000660	negative regulation of interleukin-1-mediated signaling pathway	5.519480e-7
GO:0071840	cellular component organization or biogenesis	5.627998e-7
GO:0042699	follicle-stimulating hormone signaling pathway	6.190717e-7
GO:0071842	cellular component organization at cellular level	6.492973e-7
GO:0031401	positive regulation of protein modification process	6.955723e-7
GO:0051223	regulation of protein transport	7.316504e-7
GO:0051246	regulation of protein metabolic process	7.691302e-7
GO:0002684	positive regulation of immune system process	8.505711e-7
GO:0031295	T cell costimulation	8.514252e-7
GO:0031032	actomyosin structure organization	1.001322e-6
GO:0007076	mitotic chromosome condensation	1.006338e-6
GO:0050715	positive regulation of cytokine secretion	1.051310e-6
GO:0007416	synapse assembly	1.094177e-6
GO:0006200	ATP catabolic process	1.135053e-6
GO:0050776	regulation of immune response	1.207516e-6
GO:0070663	regulation of leukocyte proliferation	1.256819e-6
GO:0050793	regulation of developmental process	1.323578e-6
GO:0070664	negative regulation of leukocyte proliferation	1.450100e-6
GO:0071900	regulation of protein serine/threonine kinase activity	1.584422e-6
GO:0006349	regulation of gene expression by genetic imprinting	1.690109e-6
GO:0023051	regulation of signaling	1.809575e-6
GO:0006936	muscle contraction	1.856082e-6
GO:0032268	regulation of cellular protein metabolic process	1.895214e-6
GO:0043039	tRNA aminoacylation	2.016749e-6
GO:0001934	positive regulation of protein phosphorylation	2.121072e-6
GO:2000659	regulation of interleukin-1-mediated signaling pathway	2.192010e-6
GO:0048739	cardiac muscle fiber development	2.205149e-6
GO:0048468	cell development	2.249099e-6
GO:0010038	response to metal ion	2.373891e-6
GO:0048523	negative regulation of cellular process	2.454707e-6
GO:0065009	regulation of molecular function	2.583024e-6
GO:0032989	cellular component morphogenesis	2.646429e-6
GO:2000648	positive regulation of stem cell proliferation	2.659984e-6
GO:0043405	regulation of MAP kinase activity	2.733104e-6
GO:0003012	muscle system process	2.961664e-6
GO:0051960	regulation of nervous system development	3.061844e-6
GO:0006688	glycosphingolipid biosynthetic process	3.303824e-6
GO:0043900	regulation of multi-organism process	3.456595e-6
GO:0002446	neutrophil mediated immunity	3.641365e-6
GO:0000819	sister chromatid segregation	3.768863e-6
GO:0010564	regulation of cell cycle process	3.797495e-6
GO:0048583	regulation of response to stimulus	3.853663e-6
GO:0032944	regulation of mononuclear cell proliferation	4.096643e-6
GO:0051251	positive regulation of lymphocyte activation	4.125075e-6
GO:0043551	regulation of phosphatidylinositol 3-kinase activity	4.265789e-6
GO:0090197	positive regulation of chemokine secretion	4.478314e-6
GO:0042692	muscle cell differentiation	4.839856e-6
GO:0045937	positive regulation of phosphate metabolic process	5.050269e-6
GO:0010646	regulation of cell communication	5.094480e-6
GO:0035051	cardiac cell differentiation	5.109349e-6
GO:0030261	chromosome condensation	5.295007e-6
GO:0009968	negative regulation of signal transduction	5.310232e-6
GO:0002502	peptide antigen assembly with MHC class I protein complex	5.361477e-6
GO:0051146	striated muscle cell differentiation	5.435564e-6
GO:0006968	cellular defense response	6.154534e-6
GO:0070076	histone lysine demethylation	6.171359e-6
GO:0002861	regulation of inflammatory response to antigenic stimulus	6.257842e-6
GO:0048856	anatomical structure development	6.903778e-6
GO:0070189	kynurenine metabolic process	7.025961e-6
GO:0043438	acetoacetic acid metabolic process	7.096716e-6
GO:0043550	regulation of lipid kinase activity	7.326654e-6
GO:0070830	tight junction assembly	7.577505e-6
GO:0048747	muscle fiber development	7.769217e-6
GO:2000026	regulation of multicellular organismal development	8.823012e-6
GO:0060174	limb bud formation	9.582576e-6
GO:0016043	cellular component organization	9.644120e-6
GO:0030098	lymphocyte differentiation	9.849017e-6
GO:0019605	butyrate metabolic process	1.000191e-5
GO:0006434	seryl-tRNA aminoacylation	1.004394e-5
GO:0006954	inflammatory response	1.007136e-5
GO:0000070	mitotic sister chromatid segregation	1.048600e-5
GO:0048145	regulation of fibroblast proliferation	1.062782e-5
GO:0043297	apical junction assembly	1.070366e-5
GO:0019441	tryptophan catabolic process to kynurenine	1.074090e-5
GO:0050670	regulation of lymphocyte proliferation	1.092710e-5
GO:0048863	stem cell differentiation	1.099962e-5
GO:0019227	neuronal action potential propagation	1.234581e-5
GO:0046649	lymphocyte activation	1.248038e-5
GO:0002437	inflammatory response to antigenic stimulus	1.253778e-5
GO:0032092	positive regulation of protein binding	1.271370e-5
GO:0042130	negative regulation of T cell proliferation	1.282026e-5
GO:0030029	actin filament-based process	1.308456e-5
GO:0023057	negative regulation of signaling	1.387600e-5
GO:0050778	positive regulation of immune response	1.424792e-5
GO:0048769	sarcomerogenesis	1.436374e-5
GO:0045091	regulation of retroviral genome replication	1.461342e-5
GO:0001541	ovarian follicle development	1.569076e-5
GO:0032940	secretion by cell	1.574346e-5
GO:0052548	regulation of endopeptidase activity	1.622573e-5
GO:0071844	cellular component assembly at cellular level	1.636322e-5
GO:0009052	pentose-phosphate shunt, non-oxidative branch	1.647784e-5
GO:0010740	positive regulation of intracellular protein kinase cascade	1.666812e-5
GO:0010648	negative regulation of cell communication	1.705631e-5
GO:0006346	methylation-dependent chromatin silencing	1.735875e-5
GO:0002253	activation of immune response	1.742854e-5
GO:0007049	cell cycle	1.829631e-5
GO:0061061	muscle structure development	1.917624e-5
GO:0012501	programmed cell death	1.918544e-5
GO:0002826	negative regulation of T-helper 1 type immune response	1.987892e-5
GO:0019538	protein metabolic process	2.003944e-5
GO:0042663	regulation of endodermal cell fate specification	2.020343e-5
GO:0010466	negative regulation of peptidase activity	2.066245e-5
GO:0000075	cell cycle checkpoint	2.095780e-5
GO:0060956	endocardial cell differentiation	2.218702e-5
GO:0055002	striated muscle cell development	2.236712e-5
GO:0048584	positive regulation of response to stimulus	2.283102e-5
GO:0060284	regulation of cell development	2.337356e-5
GO:0045595	regulation of cell differentiation	2.341493e-5
GO:0035093	spermatogenesis, exchange of chromosomal proteins	2.418904e-5
GO:0023052	signaling	2.430413e-5
GO:0051050	positive regulation of transport	2.486928e-5
GO:0048731	system development	2.516715e-5
GO:0043408	regulation of MAPKKK cascade	2.576982e-5
GO:0048585	negative regulation of response to stimulus	2.621315e-5
GO:0000278	mitotic cell cycle	2.734383e-5
GO:0009893	positive regulation of metabolic process	2.881316e-5
GO:0055008	cardiac muscle tissue morphogenesis	2.941348e-5
GO:0052547	regulation of peptidase activity	3.015212e-5
GO:0006679	glucosylceramide biosynthetic process	3.212798e-5
GO:0048519	negative regulation of biological process	3.215122e-5
GO:0007275	multicellular organismal development	3.288340e-5
GO:0048538	thymus development	3.457216e-5
GO:0009308	amine metabolic process	3.507227e-5
GO:0043501	skeletal muscle adaptation	3.592894e-5
GO:0006520	cellular amino acid metabolic process	3.602770e-5
GO:0055123	digestive system development	3.622887e-5
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	3.627455e-5
GO:0007166	cell surface receptor linked signaling pathway	3.754808e-5
GO:0007093	mitotic cell cycle checkpoint	3.762449e-5
GO:0042129	regulation of T cell proliferation	3.837944e-5
GO:0043503	skeletal muscle fiber adaptation	3.911524e-5
GO:0071902	positive regulation of protein serine/threonine kinase activity	4.029621e-5
GO:0006915	apoptosis	4.238163e-5
GO:0001954	positive regulation of cell-matrix adhesion	4.300034e-5
GO:0006611	protein export from nucleus	4.321684e-5
GO:0060396	growth hormone receptor signaling pathway	4.334546e-5
GO:0032594	protein transport within lipid bilayer	4.530078e-5
GO:0050730	regulation of peptidyl-tyrosine phosphorylation	4.618969e-5
GO:0050854	regulation of antigen receptor-mediated signaling pathway	4.630252e-5
GO:0007207	activation of phospholipase C activity by muscarinic acetylcholine receptor signaling pathway	4.695716e-5
GO:0009812	flavonoid metabolic process	4.695716e-5
GO:0048522	positive regulation of cellular process	4.733122e-5
GO:0010811	positive regulation of cell-substrate adhesion	4.811472e-5
GO:0030071	regulation of mitotic metaphase/anaphase transition	4.831887e-5
GO:0001655	urogenital system development	4.854842e-5
GO:0071780	mitotic cell cycle G2/M transition checkpoint	4.897024e-5
GO:0018160	peptidyl-pyrromethane cofactor linkage	5.051839e-5
GO:0022407	regulation of cell-cell adhesion	5.068491e-5
GO:0045597	positive regulation of cell differentiation	5.105991e-5
GO:0002863	positive regulation of inflammatory response to antigenic stimulus	5.294048e-5
GO:0045664	regulation of neuron differentiation	5.382171e-5
GO:0060548	negative regulation of cell death	5.392149e-5
GO:0010226	response to lithium ion	5.433136e-5
GO:0042493	response to drug	5.493573e-5
GO:0009611	response to wounding	5.635739e-5
GO:0032502	developmental process	5.864976e-5
GO:0070372	regulation of ERK1 and ERK2 cascade	5.969763e-5
GO:0043032	positive regulation of macrophage activation	6.092400e-5
GO:0043406	positive regulation of MAP kinase activity	6.128628e-5
GO:0009150	purine ribonucleotide metabolic process	6.156543e-5
GO:0090196	regulation of chemokine secretion	6.201797e-5
GO:0032655	regulation of interleukin-12 production	6.609327e-5
GO:0070681	glutaminyl-tRNAGln biosynthesis via transamidation	6.690931e-5
GO:0009888	tissue development	6.826534e-5
GO:0002444	myeloid leukocyte mediated immunity	6.851680e-5
GO:0048646	anatomical structure formation involved in morphogenesis	7.050004e-5
GO:0032388	positive regulation of intracellular transport	7.247151e-5
GO:0035987	endodermal cell differentiation	7.250762e-5
GO:0006464	protein modification process	7.289676e-5
GO:0050767	regulation of neurogenesis	7.420216e-5
GO:0042110	T cell activation	7.492406e-5
GO:0051347	positive regulation of transferase activity	7.523691e-5
GO:0016339	calcium-dependent cell-cell adhesion	7.890479e-5
GO:0050707	regulation of cytokine secretion	7.908585e-5
GO:0033674	positive regulation of kinase activity	8.261389e-5
GO:0060341	regulation of cellular localization	8.329254e-5
GO:0034088	maintenance of mitotic sister chromatid cohesion	8.360842e-5
GO:0001816	cytokine production	8.362376e-5
GO:0002764	immune response-regulating signaling pathway	8.655690e-5
GO:0043412	macromolecule modification	9.105754e-5
GO:0042119	neutrophil activation	9.328465e-5
GO:0030154	cell differentiation	9.423601e-5
GO:0030241	skeletal muscle myosin thick filament assembly	9.452143e-5
GO:0010604	positive regulation of macromolecule metabolic process	9.495923e-5
GO:0048869	cellular developmental process	9.675663e-5
GO:0090316	positive regulation of intracellular protein transport	9.733177e-5
GO:0014031	mesenchymal cell development	9.812630e-5
GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter	9.983389e-5
GO:0034154	toll-like receptor 7 signaling pathway	1.001595e-4
GO:0034720	histone H3-K4 demethylation	1.016551e-4
GO:0071156	regulation of cell cycle arrest	1.020618e-4
GO:0050783	cocaine metabolic process	1.026911e-4
GO:0046824	positive regulation of nucleocytoplasmic transport	1.043320e-4
GO:0030217	T cell differentiation	1.079082e-4
GO:0001819	positive regulation of cytokine production	1.080221e-4
GO:0042094	interleukin-2 biosynthetic process	1.094059e-4
GO:0060047	heart contraction	1.094691e-4
GO:0007155	cell adhesion	1.096319e-4
GO:0007094	mitotic cell cycle spindle assembly checkpoint	1.102480e-4
GO:0050654	chondroitin sulfate proteoglycan metabolic process	1.136714e-4
GO:0010470	regulation of gastrulation	1.206122e-4
GO:0045860	positive regulation of protein kinase activity	1.241651e-4
GO:2000036	regulation of stem cell maintenance	1.245486e-4
GO:0003230	cardiac atrium development	1.253123e-4
GO:0031349	positive regulation of defense response	1.290067e-4
GO:0046459	short-chain fatty acid metabolic process	1.291405e-4
GO:0072091	regulation of stem cell proliferation	1.315246e-4
GO:0002218	activation of innate immune response	1.324000e-4
GO:0051094	positive regulation of developmental process	1.332339e-4
GO:0006569	tryptophan catabolic process	1.378860e-4
GO:0006739	NADP metabolic process	1.413805e-4
GO:0003008	system process	1.432655e-4
GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	1.461274e-4
GO:0071173	spindle assembly checkpoint	1.476074e-4
GO:0042668	auditory receptor cell fate determination	1.490328e-4
GO:0071305	cellular response to vitamin D	1.500581e-4
GO:0009912	auditory receptor cell fate commitment	1.525388e-4
GO:0071174	mitotic cell cycle spindle checkpoint	1.563362e-4
GO:0051250	negative regulation of lymphocyte activation	1.590172e-4
GO:0030522	intracellular receptor mediated signaling pathway	1.609334e-4
GO:0034764	positive regulation of transmembrane transport	1.613786e-4
GO:0051726	regulation of cell cycle	1.615312e-4
GO:0006568	tryptophan metabolic process	1.615711e-4
GO:0032637	interleukin-8 production	1.630258e-4
GO:0015810	aspartate transport	1.632815e-4
GO:0001878	response to yeast	1.633658e-4
GO:0007213	muscarinic acetylcholine receptor signaling pathway	1.641487e-4
GO:0007067	mitosis	1.652234e-4
GO:0009967	positive regulation of signal transduction	1.664563e-4
GO:0007154	cell communication	1.702902e-4
GO:0030204	chondroitin sulfate metabolic process	1.733160e-4
GO:0048566	embryonic digestive tract development	1.772020e-4
GO:0044085	cellular component biogenesis	1.779002e-4
GO:0032844	regulation of homeostatic process	1.800318e-4
GO:0010647	positive regulation of cell communication	1.815662e-4
GO:0034115	negative regulation of heterotypic cell-cell adhesion	1.885969e-4
GO:0007165	signal transduction	1.929151e-4
GO:0051409	response to nitrosative stress	1.948411e-4
GO:0002544	chronic inflammatory response	1.949952e-4
GO:0071956	cellular component maintenance at cellular level	1.950734e-4
GO:0019693	ribose phosphate metabolic process	1.950734e-4
GO:0042475	odontogenesis of dentine-containing tooth	1.960777e-4
GO:0090068	positive regulation of cell cycle process	1.979310e-4
GO:0006575	cellular modified amino acid metabolic process	1.997499e-4
GO:0031507	heterochromatin formation	2.028099e-4
GO:0003007	heart morphogenesis	2.041190e-4
GO:0009698	phenylpropanoid metabolic process	2.073903e-4
GO:0022417	protein maturation by protein folding	2.109046e-4
GO:0001578	microtubule bundle formation	2.109351e-4
GO:0060415	muscle tissue morphogenesis	2.123560e-4
GO:0009719	response to endogenous stimulus	2.137522e-4
GO:0071103	DNA conformation change	2.148048e-4
GO:0003209	cardiac atrium morphogenesis	2.181923e-4
GO:0016477	cell migration	2.188730e-4
GO:0000724	double-strand break repair via homologous recombination	2.193065e-4
GO:0048048	embryonic eye morphogenesis	2.221667e-4
GO:0010035	response to inorganic substance	2.222503e-4
GO:0046854	phosphatidylinositol phosphorylation	2.227874e-4
GO:0023056	positive regulation of signaling	2.248880e-4
GO:0007010	cytoskeleton organization	2.284285e-4
GO:0042509	regulation of tyrosine phosphorylation of STAT protein	2.294496e-4
GO:0045841	negative regulation of mitotic metaphase/anaphase transition	2.317943e-4
GO:0002683	negative regulation of immune system process	2.318003e-4
GO:0055003	cardiac myofibril assembly	2.319732e-4
GO:0009259	ribonucleotide metabolic process	2.332420e-4
GO:0016199	axon midline choice point recognition	2.342053e-4
GO:0043066	negative regulation of apoptosis	2.359322e-4
GO:0002757	immune response-activating signal transduction	2.386467e-4
GO:0010716	negative regulation of extracellular matrix disassembly	2.407431e-4
GO:0002922	positive regulation of humoral immune response	2.411641e-4
GO:0048518	positive regulation of biological process	2.413737e-4
GO:0050868	negative regulation of T cell activation	2.421741e-4
GO:0031577	spindle checkpoint	2.449221e-4
GO:0045216	cell-cell junction organization	2.467790e-4
GO:0090100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	2.496810e-4
GO:0007088	regulation of mitosis	2.531000e-4
GO:0008284	positive regulation of cell proliferation	2.602733e-4
GO:0032514	positive regulation of protein phosphatase type 2B activity	2.613725e-4
GO:0006323	DNA packaging	2.661798e-4
GO:0007585	respiratory gaseous exchange	2.681042e-4
GO:0048285	organelle fission	2.707728e-4
GO:0071223	cellular response to lipoteichoic acid	2.723070e-4
GO:0070779	D-aspartate import	2.803751e-4
GO:0071514	genetic imprinting	2.857911e-4
GO:0045814	negative regulation of gene expression, epigenetic	2.879253e-4
GO:0000725	recombinational repair	2.884378e-4
GO:0051716	cellular response to stimulus	2.909116e-4
GO:0046600	negative regulation of centriole replication	2.937844e-4
GO:0043170	macromolecule metabolic process	2.941828e-4
GO:0006418	tRNA aminoacylation for protein translation	2.942674e-4
GO:0007016	cytoskeletal anchoring at plasma membrane	2.976199e-4
GO:0050714	positive regulation of protein secretion	2.987763e-4
GO:0032472	Golgi calcium ion transport	3.007888e-4
GO:0030026	cellular manganese ion homeostasis	3.007888e-4
GO:0032468	Golgi calcium ion homeostasis	3.007888e-4
GO:0071221	cellular response to bacterial lipopeptide	3.055621e-4
GO:0006974	response to DNA damage stimulus	3.059246e-4
GO:0006259	DNA metabolic process	3.079494e-4
GO:0000087	M phase of mitotic cell cycle	3.113908e-4
GO:0048534	hemopoietic or lymphoid organ development	3.116439e-4
GO:0019442	tryptophan catabolic process to acetyl-CoA	3.119919e-4
GO:0009593	detection of chemical stimulus	3.150392e-4
GO:0051704	multi-organism process	3.296978e-4
GO:0048864	stem cell development	3.335537e-4
GO:0060048	cardiac muscle contraction	3.353111e-4
GO:0018107	peptidyl-threonine phosphorylation	3.353111e-4
GO:0055001	muscle cell development	3.426967e-4
GO:0051099	positive regulation of binding	3.459714e-4
GO:0034504	protein localization to nucleus	3.499486e-4
GO:0045070	positive regulation of viral genome replication	3.635879e-4
GO:0048660	regulation of smooth muscle cell proliferation	3.687254e-4
GO:0045162	clustering of voltage-gated sodium channels	3.702534e-4
GO:0007095	mitotic cell cycle G2/M transition DNA damage checkpoint	3.792768e-4
GO:0031641	regulation of myelination	3.991820e-4
GO:0051049	regulation of transport	4.002981e-4
GO:0010942	positive regulation of cell death	4.007771e-4
GO:2001033	negative regulation of double-strand break repair via nonhomologous end joining	4.033382e-4
GO:2001038	regulation of cellular response to drug	4.033382e-4
GO:2000685	positive regulation of cellular response to X-ray	4.033382e-4
GO:0031052	chromosome breakage	4.033382e-4
GO:0003131	mesodermal-endodermal cell signaling	4.033382e-4
GO:0035978	histone H2A-S139 phosphorylation	4.033382e-4
GO:0007517	muscle organ development	4.068599e-4
GO:0007162	negative regulation of cell adhesion	4.079192e-4
GO:0030258	lipid modification	4.085468e-4
GO:0046425	regulation of JAK-STAT cascade	4.112042e-4
GO:0002520	immune system development	4.150647e-4
GO:0060485	mesenchyme development	4.174689e-4
GO:0061008	hepaticobiliary system development	4.227390e-4
GO:0009247	glycolipid biosynthetic process	4.238061e-4
GO:0009607	response to biotic stimulus	4.240504e-4
GO:0048009	insulin-like growth factor receptor signaling pathway	4.268899e-4
GO:0043331	response to dsRNA	4.271267e-4
GO:0045787	positive regulation of cell cycle	4.306019e-4
GO:0051128	regulation of cellular component organization	4.340058e-4
GO:0051346	negative regulation of hydrolase activity	4.393886e-4
GO:0002439	chronic inflammatory response to antigenic stimulus	4.419825e-4
GO:0043490	malate-aspartate shuttle	4.422911e-4
GO:0042769	DNA damage response, detection of DNA damage	4.452235e-4
GO:0044106	cellular amine metabolic process	4.512208e-4
GO:0044092	negative regulation of molecular function	4.525944e-4
GO:0010755	regulation of plasminogen activation	4.531931e-4
GO:0070665	positive regulation of leukocyte proliferation	4.549176e-4
GO:0006163	purine nucleotide metabolic process	4.559479e-4
GO:0043069	negative regulation of programmed cell death	4.630590e-4
GO:0032722	positive regulation of chemokine production	4.661046e-4
GO:0042307	positive regulation of protein import into nucleus	4.685467e-4
GO:0035092	sperm chromatin condensation	4.701069e-4
GO:0014888	striated muscle adaptation	4.779322e-4
GO:0033037	polysaccharide localization	4.804504e-4
GO:0048762	mesenchymal cell differentiation	4.813740e-4
GO:0010951	negative regulation of endopeptidase activity	4.837549e-4
GO:2000021	regulation of ion homeostasis	4.848047e-4
GO:0016192	vesicle-mediated transport	4.873424e-4
GO:0022603	regulation of anatomical structure morphogenesis	4.974974e-4
GO:0006957	complement activation, alternative pathway	5.186901e-4
GO:0045217	cell-cell junction maintenance	5.189880e-4
GO:0042396	phosphagen biosynthetic process	5.197556e-4
GO:0010424	DNA methylation on cytosine within a CG sequence	5.197556e-4
GO:0006399	tRNA metabolic process	5.234548e-4
GO:0031325	positive regulation of cellular metabolic process	5.311498e-4
GO:0048515	spermatid differentiation	5.383894e-4
GO:0030162	regulation of proteolysis	5.407232e-4
GO:0016098	monoterpenoid metabolic process	5.460984e-4
GO:0001779	natural killer cell differentiation	5.476884e-4
GO:0044030	regulation of DNA methylation	5.476884e-4
GO:0006306	DNA methylation	5.515443e-4
GO:0048565	digestive tract development	5.543644e-4
GO:0006428	isoleucyl-tRNA aminoacylation	5.556034e-4
GO:0060060	post-embryonic retina morphogenesis in camera-type eye	5.556034e-4
GO:0045665	negative regulation of neuron differentiation	5.632763e-4
GO:0042512	negative regulation of tyrosine phosphorylation of Stat1 protein	5.642950e-4
GO:0048870	cell motility	5.771739e-4
GO:0045176	apical protein localization	5.932763e-4
GO:0072075	metanephric mesenchyme development	6.004127e-4
GO:0071285	cellular response to lithium ion	6.041268e-4
GO:0002823	negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	6.092229e-4
GO:0003108	negative regulation of the force of heart contraction by chemical signal	6.111281e-4
GO:0051707	response to other organism	6.129519e-4
GO:0006721	terpenoid metabolic process	6.171099e-4
GO:0021936	regulation of cerebellar granule cell precursor proliferation	6.195789e-4
GO:0009117	nucleotide metabolic process	6.246037e-4
GO:0002920	regulation of humoral immune response	6.284009e-4
GO:0043065	positive regulation of apoptosis	6.315461e-4
GO:0035988	chondrocyte proliferation	6.335000e-4
GO:0034243	regulation of transcription elongation from RNA polymerase II promoter	6.340604e-4
GO:0009141	nucleoside triphosphate metabolic process	6.393121e-4
GO:0000082	G1/S transition of mitotic cell cycle	6.405180e-4
GO:0043068	positive regulation of programmed cell death	6.500420e-4
GO:0046822	regulation of nucleocytoplasmic transport	6.556940e-4
GO:0002040	sprouting angiogenesis	6.637242e-4
GO:0065008	regulation of biological quality	6.715432e-4
GO:0003151	outflow tract morphogenesis	6.716027e-4
GO:0009154	purine ribonucleotide catabolic process	6.729002e-4
GO:2000116	regulation of cysteine-type endopeptidase activity	6.827791e-4
GO:0070265	necrotic cell death	6.979041e-4
GO:0050708	regulation of protein secretion	6.999811e-4
GO:0048669	collateral sprouting in absence of injury	7.096429e-4
GO:0030518	steroid hormone receptor signaling pathway	7.114352e-4
GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	7.278196e-4
GO:0009653	anatomical structure morphogenesis	7.318854e-4
GO:0030155	regulation of cell adhesion	7.357981e-4
GO:2000063	positive regulation of ureter smooth muscle cell differentiation	7.367180e-4
GO:2000062	negative regulation of ureter smooth muscle cell differentiation	7.367180e-4
GO:2000358	positive regulation of kidney smooth muscle cell differentiation	7.367180e-4
GO:0080125	multicellular structure septum development	7.367180e-4
GO:2000357	negative regulation of kidney smooth muscle cell differentiation	7.367180e-4
GO:2000729	positive regulation of mesenchymal cell proliferation involved in ureter development	7.367180e-4
GO:0007502	digestive tract mesoderm development	7.367180e-4
GO:0060783	mesenchymal smoothened signaling pathway involved in prostate gland development	7.367180e-4
GO:0014858	positive regulation of skeletal muscle cell proliferation	7.367180e-4
GO:0060782	regulation of mesenchymal cell proliferation involved in prostate gland development	7.367180e-4
GO:0046534	positive regulation of photoreceptor cell differentiation	7.367180e-4
GO:0021915	neural tube development	7.379655e-4
GO:0009261	ribonucleotide catabolic process	7.432873e-4
GO:0044057	regulation of system process	7.452229e-4
GO:0050856	regulation of T cell receptor signaling pathway	7.516938e-4
GO:0051329	interphase of mitotic cell cycle	7.837850e-4
GO:0044093	positive regulation of molecular function	8.070771e-4
GO:0009144	purine nucleoside triphosphate metabolic process	8.081355e-4
GO:0042089	cytokine biosynthetic process	8.151427e-4
GO:0051170	nuclear import	8.174851e-4
GO:0000244	assembly of spliceosomal tri-snRNP	8.355546e-4
GO:0042738	exogenous drug catabolic process	8.398526e-4
GO:0046476	glycosylceramide biosynthetic process	8.507598e-4
GO:0070159	mitochondrial threonyl-tRNA aminoacylation	8.534311e-4
GO:0006051	N-acetylmannosamine metabolic process	8.534311e-4
GO:0031120	snRNA pseudouridine synthesis	8.534311e-4
GO:0048557	embryonic digestive tract morphogenesis	8.602994e-4
GO:0009168	purine ribonucleoside monophosphate biosynthetic process	8.683201e-4
GO:0007442	hindgut morphogenesis	8.705882e-4
GO:0008152	metabolic process	8.792944e-4
GO:0045839	negative regulation of mitosis	8.830820e-4
GO:0009205	purine ribonucleoside triphosphate metabolic process	8.869508e-4
GO:0034446	substrate adhesion-dependent cell spreading	8.895816e-4

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0048240	sperm capacitation	9.427477e-13
GO:0018924	mandelate metabolic process	7.287979e-10
GO:0032074	negative regulation of nuclease activity	6.703048e-9
GO:0050896	response to stimulus	5.479400e-8
GO:0055001	muscle cell development	1.116096e-7
GO:0050790	regulation of catalytic activity	2.062764e-7
GO:0032735	positive regulation of interleukin-12 production	3.318165e-7
GO:0046684	response to pyrethroid	7.132098e-7
GO:0035441	cell migration involved in vasculogenesis	9.853389e-7
GO:0017085	response to insecticide	1.166123e-6
GO:0051336	regulation of hydrolase activity	1.450297e-6
GO:0045348	positive regulation of MHC class II biosynthetic process	1.493610e-6
GO:0009636	response to toxin	1.738540e-6
GO:0006463	steroid hormone receptor complex assembly	2.118799e-6
GO:0015908	fatty acid transport	3.888539e-6
GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	5.086166e-6
GO:0042742	defense response to bacterium	7.300164e-6
GO:2001022	positive regulation of response to DNA damage stimulus	8.867926e-6
GO:0090218	positive regulation of lipid kinase activity	1.089752e-5
GO:0045346	regulation of MHC class II biosynthetic process	1.235655e-5
GO:0055002	striated muscle cell development	1.255644e-5
GO:0060479	lung cell differentiation	1.345901e-5
GO:0046005	positive regulation of circadian sleep/wake cycle, REM sleep	1.440293e-5
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	1.799035e-5
GO:0048250	mitochondrial iron ion transport	1.856321e-5
GO:0072277	metanephric glomerular capillary formation	1.856321e-5
GO:0032314	regulation of Rac GTPase activity	1.862972e-5
GO:0045919	positive regulation of cytolysis	2.042161e-5
GO:0060487	lung epithelial cell differentiation	2.484440e-5
GO:0071108	protein K48-linked deubiquitination	2.553890e-5
GO:0061298	retina vasculature development in camera-type eye	2.621861e-5
GO:0015850	organic alcohol transport	3.318444e-5
GO:0031032	actomyosin structure organization	3.516223e-5
GO:0045739	positive regulation of DNA repair	4.584387e-5
GO:0030239	myofibril assembly	4.596298e-5
GO:0070432	regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	4.903241e-5
GO:0070428	regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	4.903241e-5
GO:0052547	regulation of peptidase activity	4.912111e-5
GO:0051716	cellular response to stimulus	4.921281e-5
GO:0016578	histone deubiquitination	5.164762e-5
GO:0045666	positive regulation of neuron differentiation	5.340558e-5
GO:0065007	biological regulation	5.660868e-5
GO:0032423	regulation of mismatch repair	6.248938e-5
GO:0032425	positive regulation of mismatch repair	6.371383e-5
GO:0006766	vitamin metabolic process	6.853539e-5
GO:0006704	glucocorticoid biosynthetic process	6.990008e-5
GO:0010592	positive regulation of lamellipodium assembly	6.990008e-5
GO:0002026	regulation of the force of heart contraction	7.004291e-5
GO:0048513	organ development	7.054247e-5
GO:0002446	neutrophil mediated immunity	7.260576e-5
GO:0045637	regulation of myeloid cell differentiation	7.444810e-5
GO:0048856	anatomical structure development	8.165448e-5
GO:0046823	negative regulation of nucleocytoplasmic transport	8.296441e-5
GO:0048522	positive regulation of cellular process	8.296936e-5
GO:0048627	myoblast development	9.088156e-5
GO:2000193	positive regulation of fatty acid transport	9.433206e-5
GO:0032497	detection of lipopolysaccharide	9.463710e-5
GO:0043551	regulation of phosphatidylinositol 3-kinase activity	9.610786e-5
GO:0015909	long-chain fatty acid transport	1.045711e-4
GO:0043519	regulation of myosin II filament organization	1.149388e-4
GO:0006739	NADP metabolic process	1.150560e-4
GO:0070434	positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	1.178541e-4
GO:0070430	positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	1.178541e-4
GO:0009446	putrescine biosynthetic process	1.178541e-4
GO:0032707	negative regulation of interleukin-23 production	1.178541e-4
GO:0045362	positive regulation of interleukin-1 biosynthetic process	1.178541e-4
GO:0032049	cardiolipin biosynthetic process	1.196083e-4
GO:0071322	cellular response to carbohydrate stimulus	1.230112e-4
GO:0045638	negative regulation of myeloid cell differentiation	1.278190e-4
GO:0006282	regulation of DNA repair	1.299983e-4
GO:0007156	homophilic cell adhesion	1.436185e-4
GO:2000351	regulation of endothelial cell apoptosis	1.462051e-4
GO:0007213	muscarinic acetylcholine receptor signaling pathway	1.471922e-4
GO:0055096	low-density lipoprotein particle mediated signaling	1.486205e-4
GO:0048468	cell development	1.539126e-4
GO:0042320	regulation of circadian sleep/wake cycle, REM sleep	1.601685e-4
GO:0002521	leukocyte differentiation	1.603612e-4
GO:0009566	fertilization	1.668016e-4
GO:0006260	DNA replication	1.708509e-4
GO:0071333	cellular response to glucose stimulus	1.710837e-4
GO:0023056	positive regulation of signaling	1.800614e-4
GO:0010942	positive regulation of cell death	1.894124e-4
GO:0051604	protein maturation	1.921200e-4
GO:0031503	protein complex localization	1.972989e-4
GO:0055098	response to low-density lipoprotein particle stimulus	1.972989e-4
GO:0051329	interphase of mitotic cell cycle	1.999898e-4
GO:0006023	aminoglycan biosynthetic process	2.029327e-4
GO:0065009	regulation of molecular function	2.046369e-4
GO:0036006	cellular response to macrophage colony-stimulating factor stimulus	2.075659e-4
GO:0022603	regulation of anatomical structure morphogenesis	2.093136e-4
GO:0010647	positive regulation of cell communication	2.153663e-4
GO:0010025	wax biosynthetic process	2.255333e-4
GO:0071848	positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling	2.278941e-4
GO:0071812	positive regulation of fever generation by positive regulation of prostaglandin secretion	2.278941e-4
GO:0042756	drinking behavior	2.405007e-4
GO:0032490	detection of molecule of bacterial origin	2.405007e-4
GO:0051146	striated muscle cell differentiation	2.478981e-4
GO:0071223	cellular response to lipoteichoic acid	2.479987e-4
GO:0071402	cellular response to lipoprotein particle stimulus	2.479987e-4
GO:0030206	chondroitin sulfate biosynthetic process	2.479987e-4
GO:0032387	negative regulation of intracellular transport	2.511889e-4
GO:0042221	response to chemical stimulus	2.575539e-4
GO:0055006	cardiac cell development	2.619034e-4
GO:0035023	regulation of Rho protein signal transduction	2.703430e-4
GO:0031345	negative regulation of cell projection organization	2.739248e-4
GO:0071705	nitrogen compound transport	2.761295e-4
GO:2000249	regulation of actin cytoskeleton reorganization	2.934727e-4
GO:0009231	riboflavin biosynthetic process	2.998519e-4
GO:0009743	response to carbohydrate stimulus	3.115532e-4
GO:0031111	negative regulation of microtubule polymerization or depolymerization	3.304488e-4
GO:0046942	carboxylic acid transport	3.322418e-4
GO:0007635	chemosensory behavior	3.416085e-4
GO:0071404	cellular response to low-density lipoprotein particle stimulus	3.416085e-4
GO:0048010	vascular endothelial growth factor receptor signaling pathway	3.543859e-4
GO:0070527	platelet aggregation	3.557379e-4
GO:0032048	cardiolipin metabolic process	3.557379e-4
GO:0035790	platelet-derived growth factor receptor-alpha signaling pathway	3.570745e-4
GO:0031399	regulation of protein modification process	3.812179e-4
GO:0048241	epinephrine transport	3.850530e-4
GO:0006775	fat-soluble vitamin metabolic process	3.877753e-4
GO:0009967	positive regulation of signal transduction	3.902645e-4
GO:0050789	regulation of biological process	4.102670e-4
GO:0052548	regulation of endopeptidase activity	4.121672e-4
GO:0042727	flavin-containing compound biosynthetic process	4.223731e-4
GO:0015849	organic acid transport	4.268680e-4
GO:0043068	positive regulation of programmed cell death	4.270410e-4
GO:0046578	regulation of Ras protein signal transduction	4.403048e-4
GO:0046784	intronless viral mRNA export from host nucleus	4.432492e-4
GO:0021636	trigeminal nerve morphogenesis	4.543880e-4
GO:0015718	monocarboxylic acid transport	4.558708e-4
GO:0043065	positive regulation of apoptosis	4.687927e-4
GO:0042692	muscle cell differentiation	4.952728e-4
GO:0010591	regulation of lamellipodium assembly	5.374324e-4
GO:0043085	positive regulation of catalytic activity	5.518355e-4
GO:0051325	interphase	5.541712e-4
GO:0016199	axon midline choice point recognition	5.641192e-4
GO:0048589	developmental growth	5.699392e-4
GO:2000836	positive regulation of androgen secretion	5.725530e-4
GO:2000500	positive regulation of induction of apoptosis in response to chemical stimulus	5.725530e-4
GO:0035260	internal genitalia morphogenesis	5.725530e-4
GO:0008631	induction of apoptosis by oxidative stress	5.824672e-4
GO:0000084	S phase of mitotic cell cycle	5.824672e-4
GO:0032501	multicellular organismal process	5.864402e-4
GO:0006024	glycosaminoglycan biosynthetic process	6.165065e-4
GO:0050730	regulation of peptidyl-tyrosine phosphorylation	6.248839e-4
GO:0032892	positive regulation of organic acid transport	6.288565e-4
GO:0007154	cell communication	6.426383e-4
GO:0043550	regulation of lipid kinase activity	6.449976e-4
GO:0044093	positive regulation of molecular function	6.580508e-4
GO:0023051	regulation of signaling	6.610655e-4
GO:2001020	regulation of response to DNA damage stimulus	6.649742e-4
GO:0051056	regulation of small GTPase mediated signal transduction	6.821443e-4
GO:0008038	neuron recognition	6.919007e-4
GO:0001678	cellular glucose homeostasis	6.946653e-4
GO:0030521	androgen receptor signaling pathway	6.967484e-4
GO:0050650	chondroitin sulfate proteoglycan biosynthetic process	6.969923e-4
GO:0060317	cardiac epithelial to mesenchymal transition	7.070930e-4
GO:0006654	phosphatidic acid biosynthetic process	7.070930e-4
GO:0023052	signaling	7.181943e-4
GO:0031397	negative regulation of protein ubiquitination	7.300974e-4
GO:0016485	protein processing	7.509776e-4
GO:0071985	multivesicular body sorting pathway	7.805717e-4
GO:0060575	intestinal epithelial cell differentiation	7.818281e-4
GO:0030166	proteoglycan biosynthetic process	8.162200e-4
GO:0032227	negative regulation of synaptic transmission, dopaminergic	8.276963e-4
GO:0090317	negative regulation of intracellular protein transport	8.414548e-4
GO:0050794	regulation of cellular process	8.544548e-4
GO:0014706	striated muscle tissue development	8.559370e-4
GO:0051606	detection of stimulus	8.589520e-4
GO:0051320	S phase	8.602258e-4
GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway	8.735297e-4
GO:0010740	positive regulation of intracellular protein kinase cascade	8.764593e-4
GO:0022610	biological adhesion	8.849375e-4
GO:0006270	DNA-dependent DNA replication initiation	8.859122e-4
GO:0050779	RNA destabilization	8.870602e-4
GO:0050793	regulation of developmental process	8.888873e-4
GO:0042308	negative regulation of protein import into nucleus	9.006592e-4
GO:0055013	cardiac muscle cell development	9.117685e-4
GO:0071670	smooth muscle cell chemotaxis	9.165998e-4
GO:0010747	positive regulation of plasma membrane long-chain fatty acid transport	9.165998e-4
GO:0060981	cell migration involved in coronary angiogenesis	9.165998e-4
GO:0007507	heart development	9.440280e-4
GO:0032370	positive regulation of lipid transport	9.469604e-4
GO:0048584	positive regulation of response to stimulus	9.731388e-4
GO:0007155	cell adhesion	1.005509e-3
GO:0016198	axon choice point recognition	1.013974e-3
GO:0060428	lung epithelium development	1.032557e-3
GO:0051873	killing by host of symbiont cells	1.032725e-3
GO:0060356	leucine import	1.041598e-3
GO:0021893	cerebral cortex GABAergic interneuron fate commitment	1.041598e-3
GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment	1.041598e-3
GO:0050850	positive regulation of calcium-mediated signaling	1.042667e-3
GO:0044403	symbiosis, encompassing mutualism through parasitism	1.076507e-3
GO:0003007	heart morphogenesis	1.090548e-3
GO:0021559	trigeminal nerve development	1.101856e-3
GO:0007512	adult heart development	1.115824e-3
GO:0072104	glomerular capillary formation	1.141052e-3
GO:0033674	positive regulation of kinase activity	1.143606e-3
GO:0032655	regulation of interleukin-12 production	1.148025e-3
GO:0045214	sarcomere organization	1.246215e-3
GO:0055094	response to lipoprotein stimulus	1.260031e-3
GO:0051054	positive regulation of DNA metabolic process	1.271651e-3
GO:0043567	regulation of insulin-like growth factor receptor signaling pathway	1.286467e-3
GO:2000026	regulation of multicellular organismal development	1.292604e-3
GO:0000079	regulation of cyclin-dependent protein kinase activity	1.318827e-3
GO:0015820	leucine transport	1.329053e-3
GO:0045820	negative regulation of glycolysis	1.329053e-3
GO:0007165	signal transduction	1.347314e-3
GO:0070932	histone H3 deacetylation	1.358956e-3
GO:0048731	system development	1.363947e-3
GO:0048518	positive regulation of biological process	1.368018e-3
GO:0051447	negative regulation of meiotic cell cycle	1.386854e-3
GO:0008049	male courtship behavior	1.386854e-3
GO:0032057	negative regulation of translational initiation in response to stress	1.402891e-3
GO:0035904	aorta development	1.411838e-3
GO:0060977	coronary vasculature morphogenesis	1.467675e-3
GO:0010034	response to acetate	1.513423e-3
GO:0007181	transforming growth factor beta receptor complex assembly	1.513423e-3
GO:0010927	cellular component assembly involved in morphogenesis	1.545997e-3
GO:0002444	myeloid leukocyte mediated immunity	1.597023e-3
GO:0032609	interferon-gamma production	1.599002e-3
GO:0000086	G2/M transition of mitotic cell cycle	1.602127e-3
GO:0045410	positive regulation of interleukin-6 biosynthetic process	1.608462e-3
GO:0071702	organic substance transport	1.623104e-3
GO:0006307	DNA dealkylation involved in DNA repair	1.670321e-3
GO:0032273	positive regulation of protein polymerization	1.672922e-3
GO:0048583	regulation of response to stimulus	1.678474e-3
GO:0048242	epinephrine secretion	1.684115e-3
GO:0034983	peptidyl-lysine deacetylation	1.740804e-3
GO:0003183	mitral valve morphogenesis	1.750589e-3
GO:0015697	quaternary ammonium group transport	1.784287e-3
GO:0006261	DNA-dependent DNA replication	1.853410e-3
GO:0031652	positive regulation of heat generation	1.865631e-3
GO:0040011	locomotion	1.882637e-3
GO:0021895	cerebral cortex neuron differentiation	1.907834e-3
GO:2000345	regulation of hepatocyte proliferation	1.932524e-3
GO:0034755	iron ion transmembrane transport	1.932524e-3
GO:0031987	locomotion involved in locomotory behavior	1.933045e-3
GO:0060017	parathyroid gland development	1.939302e-3
GO:2000347	positive regulation of hepatocyte proliferation	1.939302e-3
GO:0015804	neutral amino acid transport	1.956976e-3
GO:2000833	positive regulation of steroid hormone secretion	1.983580e-3
GO:0018364	peptidyl-glutamine methylation	2.055666e-3
GO:0010507	negative regulation of autophagy	2.084200e-3
GO:0043900	regulation of multi-organism process	2.092732e-3
GO:0015837	amine transport	2.104805e-3
GO:0043903	regulation of symbiosis, encompassing mutualism through parasitism	2.122262e-3
GO:0042572	retinol metabolic process	2.138948e-3
GO:0045595	regulation of cell differentiation	2.156363e-3
GO:0033233	regulation of protein sumoylation	2.188758e-3
GO:0010975	regulation of neuron projection development	2.240286e-3
GO:0010838	positive regulation of keratinocyte proliferation	2.242466e-3
GO:0015868	purine ribonucleotide transport	2.242466e-3
GO:0006776	vitamin A metabolic process	2.248653e-3
GO:0002573	myeloid leukocyte differentiation	2.273615e-3
GO:0042698	ovulation cycle	2.279239e-3
GO:0050770	regulation of axonogenesis	2.300076e-3
GO:0035261	external genitalia morphogenesis	2.307821e-3
GO:0006826	iron ion transport	2.333766e-3
GO:0032078	negative regulation of endodeoxyribonuclease activity	2.356619e-3
GO:0006922	cleavage of lamin	2.356619e-3
GO:0002158	osteoclast proliferation	2.356619e-3
GO:0050930	induction of positive chemotaxis	2.368511e-3
GO:0009593	detection of chemical stimulus	2.386494e-3
GO:0003012	muscle system process	2.425676e-3
GO:0007286	spermatid development	2.439814e-3
GO:0070536	protein K63-linked deubiquitination	2.476436e-3
GO:0042119	neutrophil activation	2.481252e-3
GO:0022604	regulation of cell morphogenesis	2.495269e-3
GO:0071447	cellular response to hydroperoxide	2.600363e-3
GO:0015911	plasma membrane long-chain fatty acid transport	2.600363e-3
GO:0031344	regulation of cell projection organization	2.607388e-3
GO:0032989	cellular component morphogenesis	2.656364e-3
GO:0050818	regulation of coagulation	2.776264e-3
GO:2000761	positive regulation of N-terminal peptidyl-lysine acetylation	2.785113e-3
GO:0035910	ascending aorta morphogenesis	2.785113e-3
GO:0032502	developmental process	2.794698e-3
GO:0010886	positive regulation of cholesterol storage	2.846376e-3
GO:0042325	regulation of phosphorylation	2.846757e-3
GO:0031915	positive regulation of synaptic plasticity	2.887429e-3
GO:0032760	positive regulation of tumor necrosis factor production	2.890831e-3
GO:0007596	blood coagulation	2.895630e-3
GO:0015798	myo-inositol transport	2.904962e-3
GO:0061301	cerebellum vasculature morphogenesis	2.904962e-3
GO:0002541	activation of plasma proteins involved in acute inflammatory response	2.904962e-3
GO:0045596	negative regulation of cell differentiation	3.033070e-3
GO:0007218	neuropeptide signaling pathway	3.064174e-3
GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	3.080796e-3
GO:0061014	positive regulation of mRNA catabolic process	3.094906e-3
GO:0030316	osteoclast differentiation	3.125628e-3
GO:0045835	negative regulation of meiosis	3.146925e-3
GO:0021891	olfactory bulb interneuron development	3.214643e-3
GO:0014894	response to denervation involved in regulation of muscle adaptation	3.229305e-3
GO:0021885	forebrain cell migration	3.242679e-3
GO:0019220	regulation of phosphate metabolic process	3.278655e-3
GO:0071526	semaphorin-plexin signaling pathway	3.307339e-3
GO:0051347	positive regulation of transferase activity	3.345699e-3
GO:0009966	regulation of signal transduction	3.362275e-3
GO:0006812	cation transport	3.388346e-3
GO:0072239	metanephric glomerulus vasculature development	3.388718e-3
GO:0006721	terpenoid metabolic process	3.393857e-3
GO:2000334	positive regulation of blood microparticle formation	3.438648e-3
GO:0021898	commitment of multipotent stem cells to neuronal lineage in forebrain	3.438648e-3
GO:0015827	tryptophan transport	3.438648e-3
GO:0007599	hemostasis	3.461104e-3
GO:0019388	galactose catabolic process	3.464061e-3
GO:0010769	regulation of cell morphogenesis involved in differentiation	3.467346e-3
GO:0046488	phosphatidylinositol metabolic process	3.489249e-3
GO:0072224	metanephric glomerulus development	3.507860e-3
GO:0044130	negative regulation of growth of symbiont in host	3.517097e-3
GO:2000831	regulation of steroid hormone secretion	3.636964e-3
GO:0048015	phosphatidylinositol-mediated signaling	3.652490e-3
GO:0035556	intracellular signal transduction	3.684043e-3
GO:0008295	spermidine biosynthetic process	3.708449e-3
GO:0060837	blood vessel endothelial cell differentiation	3.759965e-3
GO:0007091	mitotic metaphase/anaphase transition	3.759965e-3
GO:0019321	pentose metabolic process	3.822492e-3
GO:0022029	telencephalon cell migration	3.843105e-3
GO:0050771	negative regulation of axonogenesis	3.851848e-3
GO:0034392	negative regulation of smooth muscle cell apoptosis	3.860970e-3
GO:0032854	positive regulation of Rap GTPase activity	3.860970e-3
GO:0002761	regulation of myeloid leukocyte differentiation	3.869195e-3
GO:0009635	response to herbicide	3.922411e-3
GO:0001867	complement activation, lectin pathway	3.922411e-3
GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process	3.943659e-3
GO:0048630	skeletal muscle tissue growth	3.943659e-3
GO:0006950	response to stress	3.970999e-3
GO:0031290	retinal ganglion cell axon guidance	3.976425e-3
GO:0034754	cellular hormone metabolic process	4.003558e-3
GO:0010977	negative regulation of neuron projection development	4.023516e-3
GO:0019222	regulation of metabolic process	4.032219e-3
GO:0007204	elevation of cytosolic calcium ion concentration	4.033470e-3
GO:0021892	cerebral cortex GABAergic interneuron differentiation	4.061624e-3
GO:0034446	substrate adhesion-dependent cell spreading	4.081345e-3
GO:0072573	tolerance induction to lipopolysaccharide	4.185531e-3
GO:0070433	negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	4.185531e-3
GO:2000349	negative regulation of CD40 signaling pathway	4.185531e-3
GO:0002632	negative regulation of granuloma formation	4.185531e-3
GO:0034148	negative regulation of toll-like receptor 5 signaling pathway	4.185531e-3
GO:0045945	positive regulation of transcription from RNA polymerase III promoter	4.185531e-3
GO:0070429	negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	4.185531e-3
GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline	4.215049e-3
GO:0055010	ventricular cardiac muscle tissue morphogenesis	4.243220e-3
GO:0006955	immune response	4.247605e-3
GO:0006869	lipid transport	4.321964e-3
GO:0009617	response to bacterium	4.382569e-3
GO:0006659	phosphatidylserine biosynthetic process	4.384257e-3
GO:0032069	regulation of nuclease activity	4.384257e-3
GO:0014741	negative regulation of muscle hypertrophy	4.384257e-3
GO:0032633	interleukin-4 production	4.409442e-3
GO:0001865	NK T cell differentiation	4.409442e-3
GO:0010627	regulation of intracellular protein kinase cascade	4.415964e-3
GO:2000353	positive regulation of endothelial cell apoptosis	4.417953e-3
GO:0065008	regulation of biological quality	4.453973e-3
GO:0032008	positive regulation of TOR signaling cascade	4.472304e-3
GO:0048738	cardiac muscle tissue development	4.485157e-3
GO:0051493	regulation of cytoskeleton organization	4.592727e-3
GO:0021537	telencephalon development	4.600298e-3
GO:0043901	negative regulation of multi-organism process	4.626898e-3
GO:0030574	collagen catabolic process	4.665660e-3
GO:0055003	cardiac myofibril assembly	4.698628e-3
GO:0071072	negative regulation of phospholipid biosynthetic process	4.797299e-3
GO:0071417	cellular response to organic nitrogen	4.846511e-3
GO:0061061	muscle structure development	4.847819e-3
GO:0000041	transition metal ion transport	4.895407e-3
GO:0006268	DNA unwinding involved in replication	4.962329e-3
GO:0001541	ovarian follicle development	4.999379e-3
GO:0035871	protein K11-linked deubiquitination	4.999478e-3
GO:0006709	progesterone catabolic process	4.999478e-3
GO:0007266	Rho protein signal transduction	5.063275e-3
GO:0070995	NADPH oxidation	5.127449e-3
GO:0000278	mitotic cell cycle	5.177196e-3
GO:0048791	calcium ion-dependent exocytosis of neurotransmitter	5.184869e-3
GO:0015891	siderophore transport	5.314851e-3
GO:2000116	regulation of cysteine-type endopeptidase activity	5.326544e-3
GO:0060968	regulation of gene silencing	5.394924e-3
GO:0030001	metal ion transport	5.422266e-3
GO:0009792	embryo development ending in birth or egg hatching	5.434526e-3
GO:0045065	cytotoxic T cell differentiation	5.477076e-3
GO:0001834	trophectodermal cell proliferation	5.503134e-3
GO:0070781	response to biotin	5.503134e-3
GO:0000237	leptotene	5.503134e-3
GO:0007126	meiosis	5.507263e-3
GO:0060271	cilium morphogenesis	5.515591e-3
GO:0002507	tolerance induction	5.517307e-3
GO:0045128	negative regulation of reciprocal meiotic recombination	5.532057e-3
GO:0006311	meiotic gene conversion	5.532057e-3
GO:0018023	peptidyl-lysine trimethylation	5.532057e-3
GO:0051168	nuclear export	5.544599e-3
GO:2000352	negative regulation of endothelial cell apoptosis	5.559349e-3
GO:0006733	oxidoreduction coenzyme metabolic process	5.609410e-3
GO:0021795	cerebral cortex cell migration	5.614565e-3
GO:0006310	DNA recombination	5.636307e-3
GO:0043549	regulation of kinase activity	5.652170e-3
GO:0007268	synaptic transmission	5.720051e-3
GO:0042401	cellular biogenic amine biosynthetic process	5.761207e-3
GO:0001523	retinoid metabolic process	5.763359e-3
GO:0031396	regulation of protein ubiquitination	5.770439e-3
GO:0010506	regulation of autophagy	5.831915e-3
GO:0000724	double-strand break repair via homologous recombination	5.846320e-3
GO:0006029	proteoglycan metabolic process	5.865772e-3
GO:0042330	taxis	5.885487e-3
GO:0060466	activation of meiosis involved in egg activation	5.922064e-3
GO:0071230	cellular response to amino acid stimulus	6.024670e-3
GO:0071229	cellular response to acid	6.070009e-3
GO:0014888	striated muscle adaptation	6.081941e-3
GO:0044419	interspecies interaction between organisms	6.096197e-3
GO:0001756	somitogenesis	6.130606e-3
GO:0021772	olfactory bulb development	6.167878e-3
GO:0008625	induction of apoptosis via death domain receptors	6.201188e-3
GO:0045116	protein neddylation	6.201638e-3
GO:0072110	glomerular mesangial cell proliferation	6.201638e-3
GO:0033631	cell-cell adhesion mediated by integrin	6.201638e-3
GO:0035051	cardiac cell differentiation	6.230645e-3
GO:0050864	regulation of B cell activation	6.244454e-3
GO:0010744	positive regulation of macrophage derived foam cell differentiation	6.256256e-3
GO:0006022	aminoglycan metabolic process	6.283790e-3
GO:0002637	regulation of immunoglobulin production	6.283790e-3
GO:0009893	positive regulation of metabolic process	6.311811e-3
GO:0006935	chemotaxis	6.316791e-3
GO:0045860	positive regulation of protein kinase activity	6.323021e-3
GO:0010743	regulation of macrophage derived foam cell differentiation	6.335783e-3
GO:0021988	olfactory lobe development	6.419694e-3
GO:0051702	interaction with symbiont	6.461183e-3
GO:0043403	skeletal muscle tissue regeneration	6.486529e-3
GO:0031650	regulation of heat generation	6.498700e-3
GO:0007040	lysosome organization	6.519822e-3
GO:0040007	growth	6.567697e-3
GO:0009266	response to temperature stimulus	6.686323e-3
GO:0007026	negative regulation of microtubule depolymerization	6.731904e-3
GO:0007522	visceral muscle development	6.740123e-3
GO:0006259	DNA metabolic process	6.778466e-3
GO:0070166	enamel mineralization	6.849878e-3
GO:0045329	carnitine biosynthetic process	6.935546e-3
GO:0002700	regulation of production of molecular mediator of immune response	6.976223e-3
GO:0033235	positive regulation of protein sumoylation	7.060488e-3
GO:0071071	regulation of phospholipid biosynthetic process	7.060488e-3
GO:0071902	positive regulation of protein serine/threonine kinase activity	7.093696e-3
GO:0032733	positive regulation of interleukin-10 production	7.195043e-3
GO:0009595	detection of biotic stimulus	7.204630e-3
GO:0051568	histone H3-K4 methylation	7.204630e-3
GO:0060384	innervation	7.313669e-3
GO:2000426	negative regulation of apoptotic cell clearance	7.345097e-3
GO:0030203	glycosaminoglycan metabolic process	7.358137e-3
GO:0030838	positive regulation of actin filament polymerization	7.383220e-3
GO:0006811	ion transport	7.389209e-3
GO:0035020	regulation of Rac protein signal transduction	7.575952e-3
GO:0031442	positive regulation of mRNA 3'-end processing	7.660102e-3
GO:0001932	regulation of protein phosphorylation	7.662019e-3
GO:0006700	C21-steroid hormone biosynthetic process	7.676670e-3
GO:0060537	muscle tissue development	7.700621e-3
GO:0007186	G-protein coupled receptor protein signaling pathway	7.756092e-3
GO:0016337	cell-cell adhesion	7.770951e-3
GO:0035907	dorsal aorta development	7.792454e-3
GO:0061039	ovum-producing ovary development	7.798765e-3
GO:0071418	cellular response to amine stimulus	7.909461e-3
GO:0046496	nicotinamide nucleotide metabolic process	7.937013e-3
GO:0045494	photoreceptor cell maintenance	7.952144e-3
GO:0034140	negative regulation of toll-like receptor 3 signaling pathway	7.974279e-3
GO:0019226	transmission of nerve impulse	7.975233e-3
GO:0008037	cell recognition	7.979037e-3
GO:0032318	regulation of Ras GTPase activity	7.995435e-3
GO:0031440	regulation of mRNA 3'-end processing	8.054804e-3
GO:0030204	chondroitin sulfate metabolic process	8.076254e-3
GO:0043122	regulation of I-kappaB kinase/NF-kappaB cascade	8.163163e-3
GO:0050777	negative regulation of immune response	8.163242e-3
GO:0043009	chordate embryonic development	8.198011e-3
GO:0007033	vacuole organization	8.205157e-3
GO:0070723	response to cholesterol	8.266701e-3
GO:0050848	regulation of calcium-mediated signaling	8.289090e-3
GO:2000739	regulation of mesenchymal stem cell differentiation	8.293371e-3
GO:0002250	adaptive immune response	8.359435e-3
GO:0003208	cardiac ventricle morphogenesis	8.360286e-3
GO:0021644	vagus nerve morphogenesis	8.380735e-3
GO:0009605	response to external stimulus	8.382303e-3
GO:0060631	regulation of meiosis I	8.396126e-3
GO:0010876	lipid localization	8.406329e-3
GO:2000736	regulation of stem cell differentiation	8.410892e-3
GO:0000725	recombinational repair	8.439930e-3
GO:0006646	phosphatidylethanolamine biosynthetic process	8.483839e-3
GO:0015695	organic cation transport	8.545942e-3
GO:0009101	glycoprotein biosynthetic process	8.561118e-3
GO:0042268	regulation of cytolysis	8.695380e-3
GO:0003229	ventricular cardiac muscle tissue development	8.696931e-3
GO:0046883	regulation of hormone secretion	8.717998e-3
GO:0006974	response to DNA damage stimulus	8.765035e-3
GO:0071900	regulation of protein serine/threonine kinase activity	8.829485e-3
GO:0009653	anatomical structure morphogenesis	8.865364e-3
GO:0033603	positive regulation of dopamine secretion	8.872018e-3
GO:0015871	choline transport	8.881360e-3
GO:0043200	response to amino acid stimulus	8.902140e-3
GO:0007435	salivary gland morphogenesis	8.930261e-3
GO:0010884	positive regulation of lipid storage	8.951842e-3
GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	8.951842e-3
GO:0014874	response to stimulus involved in regulation of muscle adaptation	8.976362e-3
GO:0022403	cell cycle phase	9.125396e-3
GO:0051321	meiotic cell cycle	9.126824e-3
GO:0051704	multi-organism process	9.177569e-3
GO:0010470	regulation of gastrulation	9.189128e-3
GO:0031114	regulation of microtubule depolymerization	9.244277e-3