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{{MCL_coexpression_mm9
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to copper ion;4.14223155268884e-07;17750,17748!GO:0010273;detoxification of copper ion;4.14223155268884e-07;17750,17748!GO:0007263;nitric oxide mediated signal transduction;5.52297540358513e-07;17750,17748!GO:0006882;cellular zinc ion homeostasis;8.28446310537767e-07;17750,17748!GO:0055069;zinc ion homeostasis;8.28446310537767e-07;17750,17748!GO:0010038;response to metal ion;2.07111577634442e-06;17750,17748!GO:0010035;response to inorganic substance;3.07708629628314e-06;17750,17748!GO:0009636;response to toxin;5.90267996258159e-06;17750,17748!GO:0030005;cellular di-, tri-valent inorganic cation homeostasis;0.000130503306307213;17750,17748!GO:0055066;di-, tri-valent inorganic cation homeostasis;0.000130503306307213;17750,17748!GO:0030003;cellular cation homeostasis;0.000130503306307213;17750,17748!GO:0055080;cation homeostasis;0.000130503306307213;17750,17748!GO:0055082;cellular chemical homeostasis;0.000208788195167673;17750,17748!GO:0006873;cellular ion homeostasis;0.000208788195167673;17750,17748!GO:0050801;ion homeostasis;0.000252123827173661;17750,17748!GO:0048878;chemical homeostasis;0.000359886823724789;17750,17748!GO:0019725;cellular homeostasis;0.000359886823724789;17750,17748!GO:0042592;homeostatic process;0.000802764474911096;17750,17748!GO:0042221;response to chemical stimulus;0.00129721611498995;17750,17748!GO:0065008;regulation of biological quality;0.0025646626658473;17750,17748!GO:0007242;intracellular signaling cascade;0.006372724619251;17750,17748!GO:0005507;copper ion binding;0.0123536030994868;17748!GO:0006875;cellular metal ion homeostasis;0.0142545463802805;17748!GO:0055065;metal ion homeostasis;0.0142545463802805;17748!GO:0008270;zinc ion binding;0.018566707919691;17750,17748!GO:0046914;transition metal ion binding;0.0274975137905994;17750,17748!GO:0005764;lysosome;0.0304599490349778;17748!GO:0000323;lytic vacuole;0.0304599490349778;17748!GO:0005773;vacuole;0.0330234601740568;17748!GO:0043169;cation 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|gostat_on_MCL_coexpression=GO:0046688;response to copper ion;4.14223155268884e-07;17750,17748!GO:0010273;detoxification of copper ion;4.14223155268884e-07;17750,17748!GO:0007263;nitric oxide mediated signal transduction;5.52297540358513e-07;17750,17748!GO:0006882;cellular zinc ion homeostasis;8.28446310537767e-07;17750,17748!GO:0055069;zinc ion homeostasis;8.28446310537767e-07;17750,17748!GO:0010038;response to metal ion;2.07111577634442e-06;17750,17748!GO:0010035;response to inorganic substance;3.07708629628314e-06;17750,17748!GO:0009636;response to toxin;5.90267996258159e-06;17750,17748!GO:0030005;cellular di-, tri-valent inorganic cation homeostasis;0.000130503306307213;17750,17748!GO:0055066;di-, tri-valent inorganic cation homeostasis;0.000130503306307213;17750,17748!GO:0030003;cellular cation homeostasis;0.000130503306307213;17750,17748!GO:0055080;cation homeostasis;0.000130503306307213;17750,17748!GO:0055082;cellular chemical homeostasis;0.000208788195167673;17750,17748!GO:0006873;cellular ion homeostasis;0.000208788195167673;17750,17748!GO:0050801;ion homeostasis;0.000252123827173661;17750,17748!GO:0048878;chemical homeostasis;0.000359886823724789;17750,17748!GO:0019725;cellular homeostasis;0.000359886823724789;17750,17748!GO:0042592;homeostatic process;0.000802764474911096;17750,17748!GO:0042221;response to chemical stimulus;0.00129721611498995;17750,17748!GO:0065008;regulation of biological quality;0.0025646626658473;17750,17748!GO:0007242;intracellular signaling cascade;0.006372724619251;17750,17748!GO:0005507;copper ion binding;0.0123536030994868;17748!GO:0006875;cellular metal ion homeostasis;0.0142545463802805;17748!GO:0055065;metal ion homeostasis;0.0142545463802805;17748!GO:0008270;zinc ion binding;0.018566707919691;17750,17748!GO:0046914;transition metal ion binding;0.0274975137905994;17750,17748!GO:0005764;lysosome;0.0304599490349778;17748!GO:0000323;lytic vacuole;0.0304599490349778;17748!GO:0005773;vacuole;0.0330234601740568;17748!GO:0043169;cation binding;0.0458567677081809;17750,17748!
|ontology_enrichment_celltype=CL:0000333!2.70e-07!10;CL:0000095!2.70e-07!10;CL:0000243!2.70e-07!10;CL:0000123!2.70e-07!10;CL:0000125!2.70e-07!10;CL:0000030!2.70e-07!10;CL:0000339!2.70e-07!10;CL:0002453!7.45e-07!8
|ontology_enrichment_disease=
|ontology_enrichment_uberon=
|tfbs_overrepresentation_for_novel_motifs=0.29262,0.286791,0.269904,0.329881,0.176699,0.342839,0.425757,0.345089,0.732132,0.0181537,0.385334,0.414631,0.106288,0.437133,0.189961,0,0.619876,0.980191,0.096222,1.06389,0.238546,0.117252,0.436294,1.58761,0.276437,0.4628,1.05365,0.949712,1.15025,0.231659,0.349031,0.717576,0.973026,0.0786762,0.556756,0.308746,0.161521,1.0583,0.144953,0.391645,0.173534,0.353696,0.478787,1.06512,0.351346,0.319944,1.34233,0.9813,0.97944,1.15963,0.603113,0.488021,0.829247,0.855661,0.87275,1.12875,0.223087,0.40287,0.288386,0.441884,0.698157,0.496904,0.769309,0.592318,0.45416,0.631188,1.00675,1.3527,0.693631,1.20659,0.253722,0.110167,0.0307733,0.905636,0.277092,3.1743,0.270351,0.532872,0.681539,0.242107,0.357936,0.636582,1.23994,0.333618,0.792744,0.444993,1.07574,1.80787,1.3522,1.51408,1.07554,0.797601,0.730003,1.02436,0.141946,0.805383,0.104462,0.732731,0.543917,0.197581,0.161581,0.717305,0.838603,0.603683,0.602672,0.353298,0.660145,0.372438,0.246223,1.94237,0.286453,0.840348,1.95821,0.390066,1.0825,0.512539,0.566805,0.886406,1.50549,0.479408,0.910937,1.4028,0.464505,1.3176,1.13603,0.685116,0.433317,0.723425,1.00525,0.183744,0.821997,0.323373,0.976125,0.456508,1.10385,0.0275241,0.300001,0.35497,1.05527,1.88134,1.48237,1.01139,1.19763,0.727736,1.45372,0.354106,0.546641,1.84176,0.302077,0.178088,0.507931,0.0240729,0.857198,0.133365,0.455644,0.93735,0.488969,0.199652,0.290467,0.299755,1.06466,0.791909,0.685546,0.776587,0.593295,0.448733,0.160658,3.81216,0.0207556
|tfbs_overrepresentation_jaspar=MA0003.1;0.399107,MA0004.1;4.29451,MA0006.1;0.547312,MA0007.1;0.850001,MA0009.1;0.743257,MA0014.1;0.0199707,MA0017.1;0.207884,MA0019.1;0.567591,MA0024.1;0.70077,MA0025.1;0.971686,MA0027.1;2.37948,MA0028.1;0.194782,MA0029.1;0.679737,MA0030.1;0.686088,MA0031.1;1.56948,MA0038.1;0.462726,MA0040.1;0.755433,MA0041.1;0.263922,MA0042.1;0.252679,MA0043.1;0.837621,MA0046.1;0.778239,MA0048.1;0.769903,MA0050.1;0.365212,MA0051.1;0.471092,MA0052.1;0.76328,MA0055.1;8.361,MA0056.1;0,MA0057.1;0.048013,MA0058.1;1.27846,MA0059.1;1.31756,MA0060.1;0.12537,MA0061.1;0.147394,MA0063.1;0,MA0066.1;0.452472,MA0067.1;1.08124,MA0068.1;0.187364,MA0069.1;0.76361,MA0070.1;0.75417,MA0071.1;0.364454,MA0072.1;0.745922,MA0073.1;0.160336,MA0074.1;0.419185,MA0076.1;0.223625,MA0077.1;0.724865,MA0078.1;0.502121,MA0081.1;0.277253,MA0083.1;0.836845,MA0084.1;1.4063,MA0087.1;0.794721,MA0088.1;0.0293443,MA0089.1;0,MA0090.1;0.299987,MA0091.1;0.342071,MA0092.1;0.812369,MA0093.1;3.24626,MA0095.1;0,MA0098.1;0,MA0100.1;1.85374,MA0101.1;0.265031,MA0103.1;0.216742,MA0105.1;0.556739,MA0106.1;0.509454,MA0107.1;0.211681,MA0108.2;1.4389,MA0109.1;0,MA0111.1;0.312463,MA0113.1;1.21288,MA0114.1;0.876865,MA0115.1;0.84036,MA0116.1;0.186271,MA0117.1;0.808813,MA0119.1;0.265536,MA0122.1;0.828211,MA0124.1;1.02871,MA0125.1;0.955734,MA0130.1;0,MA0131.1;0.563262,MA0132.1;0,MA0133.1;0,MA0135.1;0.873285,MA0136.1;0.437601,MA0139.1;0.103495,MA0140.1;0.408417,MA0141.1;0.233109,MA0142.1;0.63775,MA0143.1;0.49828,MA0144.1;0.88666,MA0145.1;0.0329586,MA0146.1;0.0276106,MA0147.1;2.83941,MA0148.1;1.63329,MA0149.1;0.269772,MA0062.2;0.0791588,MA0035.2;0.412747,MA0039.2;0.00487869,MA0138.2;0.555696,MA0002.2;0.343346,MA0137.2;0.230686,MA0104.2;2.41329,MA0047.2;3.01952,MA0112.2;0.57262,MA0065.2;0.133827,MA0150.1;0.849777,MA0151.1;0,MA0152.1;0.46211,MA0153.1;0.889592,MA0154.1;0.434137,MA0155.1;0.0394399,MA0156.1;0.222905,MA0157.1;0.606944,MA0158.1;0,MA0159.1;0.495113,MA0160.1;0.347545,MA0161.1;0,MA0162.1;0.0355033,MA0163.1;0.198448,MA0164.1;0.437937,MA0080.2;0.212408,MA0018.2;0.446948,MA0099.2;0.549696,MA0079.2;0.0102382,MA0102.2;1.45844,MA0258.1;0.421574,MA0259.1;3.52447,MA0442.1;0
}}

Latest revision as of 15:41, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr12:5649804..5649807,+p@chr12:5649804..5649807
+
Mm9::chr12:5649934..5649959,+p@chr12:5649934..5649959
+
Mm9::chr8:96696674..96696692,+p1@Mt2
Mm9::chr8:96697253..96697294,+p@chr8:96697253..96697294
+
Mm9::chr8:96697364..96697394,-p@chr8:96697364..96697394
-
Mm9::chr8:96703134..96703148,+p1@Mt1
Mm9::chr8:96703993..96704103,+p@chr8:96703993..96704103
+
Mm9::chr8:96704054..96704065,-p@chr8:96704054..96704065
-
Mm9::chr8:96704117..96704156,+p@chr8:96704117..96704156
+
Mm9::chr8:96704126..96704155,-p@chr8:96704126..96704155
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Mm9::chr8:96704157..96704191,-p@chr8:96704157..96704191
-


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0046688response to copper ion4.14223155268884e-07
GO:0010273detoxification of copper ion4.14223155268884e-07
GO:0007263nitric oxide mediated signal transduction5.52297540358513e-07
GO:0006882cellular zinc ion homeostasis8.28446310537767e-07
GO:0055069zinc ion homeostasis8.28446310537767e-07
GO:0010038response to metal ion2.07111577634442e-06
GO:0010035response to inorganic substance3.07708629628314e-06
GO:0009636response to toxin5.90267996258159e-06
GO:0030005cellular di-, tri-valent inorganic cation homeostasis0.000130503306307213
GO:0055066di-, tri-valent inorganic cation homeostasis0.000130503306307213
GO:0030003cellular cation homeostasis0.000130503306307213
GO:0055080cation homeostasis0.000130503306307213
GO:0055082cellular chemical homeostasis0.000208788195167673
GO:0006873cellular ion homeostasis0.000208788195167673
GO:0050801ion homeostasis0.000252123827173661
GO:0048878chemical homeostasis0.000359886823724789
GO:0019725cellular homeostasis0.000359886823724789
GO:0042592homeostatic process0.000802764474911096
GO:0042221response to chemical stimulus0.00129721611498995
GO:0065008regulation of biological quality0.0025646626658473
GO:0007242intracellular signaling cascade0.006372724619251
GO:0005507copper ion binding0.0123536030994868
GO:0006875cellular metal ion homeostasis0.0142545463802805
GO:0055065metal ion homeostasis0.0142545463802805
GO:0008270zinc ion binding0.018566707919691
GO:0046914transition metal ion binding0.0274975137905994
GO:0005764lysosome0.0304599490349778
GO:0000323lytic vacuole0.0304599490349778
GO:0005773vacuole0.0330234601740568
GO:0043169cation binding0.0458567677081809



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br><br><br>


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.399107
MA0004.14.29451
MA0006.10.547312
MA0007.10.850001
MA0009.10.743257
MA0014.10.0199707
MA0017.10.207884
MA0019.10.567591
MA0024.10.70077
MA0025.10.971686
MA0027.12.37948
MA0028.10.194782
MA0029.10.679737
MA0030.10.686088
MA0031.11.56948
MA0038.10.462726
MA0040.10.755433
MA0041.10.263922
MA0042.10.252679
MA0043.10.837621
MA0046.10.778239
MA0048.10.769903
MA0050.10.365212
MA0051.10.471092
MA0052.10.76328
MA0055.18.361
MA0056.10
MA0057.10.048013
MA0058.11.27846
MA0059.11.31756
MA0060.10.12537
MA0061.10.147394
MA0063.10
MA0066.10.452472
MA0067.11.08124
MA0068.10.187364
MA0069.10.76361
MA0070.10.75417
MA0071.10.364454
MA0072.10.745922
MA0073.10.160336
MA0074.10.419185
MA0076.10.223625
MA0077.10.724865
MA0078.10.502121
MA0081.10.277253
MA0083.10.836845
MA0084.11.4063
MA0087.10.794721
MA0088.10.0293443
MA0089.10
MA0090.10.299987
MA0091.10.342071
MA0092.10.812369
MA0093.13.24626
MA0095.10
MA0098.10
MA0100.11.85374
MA0101.10.265031
MA0103.10.216742
MA0105.10.556739
MA0106.10.509454
MA0107.10.211681
MA0108.21.4389
MA0109.10
MA0111.10.312463
MA0113.11.21288
MA0114.10.876865
MA0115.10.84036
MA0116.10.186271
MA0117.10.808813
MA0119.10.265536
MA0122.10.828211
MA0124.11.02871
MA0125.10.955734
MA0130.10
MA0131.10.563262
MA0132.10
MA0133.10
MA0135.10.873285
MA0136.10.437601
MA0139.10.103495
MA0140.10.408417
MA0141.10.233109
MA0142.10.63775
MA0143.10.49828
MA0144.10.88666
MA0145.10.0329586
MA0146.10.0276106
MA0147.12.83941
MA0148.11.63329
MA0149.10.269772
MA0062.20.0791588
MA0035.20.412747
MA0039.20.00487869
MA0138.20.555696
MA0002.20.343346
MA0137.20.230686
MA0104.22.41329
MA0047.23.01952
MA0112.20.57262
MA0065.20.133827
MA0150.10.849777
MA0151.10
MA0152.10.46211
MA0153.10.889592
MA0154.10.434137
MA0155.10.0394399
MA0156.10.222905
MA0157.10.606944
MA0158.10
MA0159.10.495113
MA0160.10.347545
MA0161.10
MA0162.10.0355033
MA0163.10.198448
MA0164.10.437937
MA0080.20.212408
MA0018.20.446948
MA0099.20.549696
MA0079.20.0102382
MA0102.21.45844
MA0258.10.421574
MA0259.13.52447
MA0442.10
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