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{{CL
{{CL
|id=CL:0000501
|alt_id=
|name=granulosa cell
|namespace=cell;;efo
|def="A supporting cell for the developing female gamete in the ovary of mammals. They develop from the coelomic epithelial cells of the gonadal ridge. Granulosa cells form a single layer around the mammalian oocyte in the primordial ovarian follicle and advance to form a multilayered cumulus oophorus surrounding the ovum in the Graafian follicle. The major functions of granulosa cells include the production of steroids and LH receptors." [MESH:A.05.360.319.114.630.535.200]
|xref=BTO:0000542;;FMA:18718
|is_a=CL:0000174;;CL:0002174;;EFO:0002962
|synonym="granulosa cell of ovary" EXACT []
|comment=
|comment=
|alt_id=
|disjoint_from=
|union_of=
|created_by=
|created_by=
|obo_creation_date=
|def="A supporting cell for the developing female gamete in the ovary of mammals. They develop from the coelomic epithelial cells of the gonadal ridge. Granulosa cells form a single layer around the mammalian oocyte in the primordial ovarian follicle and advance to form a multilayered cumulus oophorus surrounding the ovum in the Graafian follicle. The major functions of granulosa cells include the production of steroids and LH receptors." [MESH:A.05.360.319.114.630.535.200]
|subset=
|derives_from=
|derives_from=
|develops_from=
|develops_from=
|disjoint_from=
|has_quality=
|has_quality=
|id=CL:0000501
|is_a=CL:0000174 ;;CL:0002174
|is_obsolete=
|located_in=
|located_in=
|name=granulosa cell
|namespace=cell;;efo
|obo_creation_date=
|part_of=
|part_of=
|preceded_by=
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl.owl;;IAO:0000412 http://purl.obolibrary.org/obo/efo.owl
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl.owl;;IAO:0000412 http://purl.obolibrary.org/obo/efo.owl
|is_obsolete=
|subset=
|preceded_by=
|synonym="granulosa cell of ovary" EXACT []
|union_of=
|xref=BTO:0000542;;FMA:18718
}}
}}

Revision as of 10:18, 12 September 2014

Name:granulosa cell
Namespace:cell;;efo
Definition:"A supporting cell for the developing female gamete in the ovary of mammals. They develop from the coelomic epithelial cells of the gonadal ridge. Granulosa cells form a single layer around the mammalian oocyte in the primordial ovarian follicle and advance to form a multilayered cumulus oophorus surrounding the ovum in the Graafian follicle. The major functions of granulosa cells include the production of steroids and LH receptors." [MESH:A.05.360.319.114.630.535.200]
Xrefs:
links:

BTO:0000542

FMA:18718
Synonyms: "granulosa cell of ovary" EXACT []


Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:CL:0000174(steroid hormone secreting cell),CL:0002174(follicular cell of ovary)



Children


derives from:FF:0102285 (granulosa cell line sample)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)


FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.

Human (Homo sapiens)

Mouse (Mus musculus)


Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000501 (granulosa cell), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
4.66e-66FFCP PHASE2:Hg19::chr1:248067410..248067413,+#_47cd29ac5e38496c48e2f5fd7085a77ep@chr1:248067410..248067413, +
4.66e-66FFCP PHASE1:Hg19::chr1:248067410..248067413,+#_47cd29ac5e38496c48e2f5fd7085a77ep@chr1:248067410..248067413, +
1.46e-50FFCP PHASE1:Hg19::chr2:227587084..227587105,+#_84877510a455ccbedaa5b4d6566d8c4cp@chr2:227587084..227587105, +
1.46e-50FFCP PHASE2:Hg19::chr2:227587084..227587105,+#_84877510a455ccbedaa5b4d6566d8c4cp@chr2:227587084..227587105, +
2.42e-50FFCP PHASE2:Hg19::chr12:78359973..78359982,+#_9ad56f36d3143c94eca9625171e36178p34@NAV3
2.42e-50FFCP PHASE1:Hg19::chr12:78359973..78359982,+#_9ad56f36d3143c94eca9625171e36178p34@NAV3
1.48e-40FFCP PHASE1:Hg19::chr11:77282391..77282402,+#_9dafebf019e9e524d78c8f6ec25e517bp@chr11:77282391..77282402, +
1.48e-40FFCP PHASE2:Hg19::chr11:77282391..77282402,+#_9dafebf019e9e524d78c8f6ec25e517bp@chr11:77282391..77282402, +
2.21e-40FFCP PHASE1:Hg19::chr9:124044161..124044173,+#_d84423f5303d23c62b85aeb799a53297p@chr9:124044161..124044173, +
2.21e-40FFCP PHASE2:Hg19::chr9:124044161..124044173,+#_d84423f5303d23c62b85aeb799a53297p@chr9:124044161..124044173, +
3.61e-34FFCP PHASE2:Hg19::chr1:185853036..185853046,+#_1d3636ae16fc0e8273fe7068bd3f5b5cp@chr1:185853036..185853046, +
3.61e-34FFCP PHASE1:Hg19::chr1:185853036..185853046,+#_1d3636ae16fc0e8273fe7068bd3f5b5cp@chr1:185853036..185853046, +
5.05e-34FFCP PHASE2:Hg19::chr1:186116540..186116557,+#_23a499ee374415b78289ce75fe426532p@chr1:186116540..186116557, +
5.05e-34FFCP PHASE1:Hg19::chr1:186116540..186116557,+#_23a499ee374415b78289ce75fe426532p@chr1:186116540..186116557, +
5.05e-34FFCP PHASE1:Hg19::chr4:138999555..138999575,-#_23a499ee374415b78289ce75fe426532p@chr4:138999555..138999575, -
5.05e-34FFCP PHASE2:Hg19::chr1:248080895..248080906,+#_23a499ee374415b78289ce75fe426532p@chr1:248080895..248080906, +
5.05e-34FFCP PHASE1:Hg19::chr1:248080895..248080906,+#_23a499ee374415b78289ce75fe426532p@chr1:248080895..248080906, +
5.05e-34FFCP PHASE2:Hg19::chr4:138999555..138999575,-#_23a499ee374415b78289ce75fe426532p@chr4:138999555..138999575, -
7.06e-34FFCP PHASE2:Hg19::chr1:185720104..185720113,+#_022b59984677a7b0de98938e754e26cfp@chr1:185720104..185720113, +
7.06e-34FFCP PHASE1:Hg19::chr1:185720104..185720113,+#_022b59984677a7b0de98938e754e26cfp@chr1:185720104..185720113, +
9.99e-30FFCP PHASE1:Hg19::chr5:145427166..145427178,+#_924d0aa15b99ddbe47b99e62b4f14df5p@chr5:145427166..145427178, +
9.99e-30FFCP PHASE2:Hg19::chr5:145427166..145427178,+#_924d0aa15b99ddbe47b99e62b4f14df5p@chr5:145427166..145427178, +
1.33e-29FFCP PHASE1:Hg19::chr18:19748482..19748490,-#_ab9c120c26256af1688ebdddcd0ecc89p@chr18:19748482..19748490, -
1.33e-29FFCP PHASE1:Hg19::chr9:32783532..32783551,+#_ab9c120c26256af1688ebdddcd0ecc89p2@TMEM215
1.33e-29FFCP PHASE2:Hg19::chr18:19748482..19748490,-#_ab9c120c26256af1688ebdddcd0ecc89p@chr18:19748482..19748490, -
1.33e-29FFCP PHASE1:Hg19::chr3:111633072..111633073,+#_ab9c120c26256af1688ebdddcd0ecc89p@chr3:111633072..111633073, +
1.33e-29FFCP PHASE2:Hg19::chr9:32783532..32783551,+#_ab9c120c26256af1688ebdddcd0ecc89p2@TMEM215
1.33e-29FFCP PHASE2:Hg19::chr3:111633072..111633073,+#_ab9c120c26256af1688ebdddcd0ecc89p@chr3:111633072..111633073, +
2.37e-29FFCP PHASE1:Hg19::chr6:5261661..5261664,-#_678d8bfcbc7593eb013058ec0ce2694ap7@LYRM4
2.37e-29FFCP PHASE1:Hg19::chr11:120110546..120110551,-#_678d8bfcbc7593eb013058ec0ce2694ap@chr11:120110546..120110551, -
2.37e-29FFCP PHASE1:Hg19::chr11:46848363..46848374,-#_678d8bfcbc7593eb013058ec0ce2694ap6@CKAP5
2.37e-29FFCP PHASE2:Hg19::chr11:120110546..120110551,-#_678d8bfcbc7593eb013058ec0ce2694ap@chr11:120110546..120110551, -
2.37e-29FFCP PHASE1:Hg19::chr8:11534512..11534519,+#_678d8bfcbc7593eb013058ec0ce2694ap7@GATA4
2.37e-29FFCP PHASE2:Hg19::chr6:5261661..5261664,-#_678d8bfcbc7593eb013058ec0ce2694ap7@LYRM4
2.37e-29FFCP PHASE2:Hg19::chr11:46848363..46848374,-#_678d8bfcbc7593eb013058ec0ce2694ap6@CKAP5
2.37e-29FFCP PHASE2:Hg19::chr8:11534512..11534519,+#_678d8bfcbc7593eb013058ec0ce2694ap7@GATA4
3.16e-29FFCP PHASE2:Hg19::chr2:49381628..49381639,-#_d94d256d0375fe080a5047bd1052fc4bp2@FSHR
3.16e-29FFCP PHASE1:Hg19::chr2:49381628..49381639,-#_d94d256d0375fe080a5047bd1052fc4bp2@FSHR
2.16e-26FFCP PHASE1:Hg19::chr11:46887017..46887024,-#_0116f02832e4ffc2c896ccb5f44dac65p@chr11:46887017..46887024, -
2.16e-26FFCP PHASE2:Hg19::chr11:46887017..46887024,-#_0116f02832e4ffc2c896ccb5f44dac65p@chr11:46887017..46887024, -
3.58e-26FFCP PHASE1:Hg19::chr17:6374648..6374688,-#_f41141538d902162c73a5d5fd366f78ep@chr17:6374648..6374688, -
3.58e-26FFCP PHASE2:Hg19::chr17:6374648..6374688,-#_f41141538d902162c73a5d5fd366f78ep@chr17:6374648..6374688, -
1.26e-25FFCP PHASE1:Hg19::chr5:145340760..145340764,+#_8ec7c705ed225b85f3c73cc6cf649bb6p@chr5:145340760..145340764, +
1.26e-25FFCP PHASE2:Hg19::chr5:145340760..145340764,+#_8ec7c705ed225b85f3c73cc6cf649bb6p@chr5:145340760..145340764, +
1.34e-23FFCP PHASE1:Hg19::chr5:83644408..83644410,-#_e0f663952b062f22595e9edfe5813b94p@chr5:83644408..83644410, -
1.34e-23FFCP PHASE2:Hg19::chr5:83644408..83644410,-#_e0f663952b062f22595e9edfe5813b94p@chr5:83644408..83644410, -
1.67e-23FFCP PHASE2:Hg19::chr3:197026018..197026029,-#_cab4a601933c7360740597d1608b361bp34@DLG1
1.67e-23FFCP PHASE1:Hg19::chr3:197026018..197026029,-#_cab4a601933c7360740597d1608b361bp34@DLG1
3.28e-23FFCP PHASE1:Hg19::chr11:1580303..1580327,-#_0c01279392cc78ab23eaa943a1457a9dp@chr11:1580303..1580327, -
3.28e-23FFCP PHASE2:Hg19::chr11:1580303..1580327,-#_0c01279392cc78ab23eaa943a1457a9dp@chr11:1580303..1580327, -
4.1e-23FFCP PHASE2:Hg19::chr2:204534759..204534765,+#_1d703ff6f195dc4fc90d6978853daf3ap@chr2:204534759..204534765, +
4.1e-23FFCP PHASE1:Hg19::chr2:204534759..204534765,+#_1d703ff6f195dc4fc90d6978853daf3ap@chr2:204534759..204534765, +
5.13e-23FFCP PHASE1:Hg19::chr10:45496353..45496379,-#_8e3709ab2117b46ea636dbf54153784bp6@C10orf25
5.13e-23FFCP PHASE2:Hg19::chr10:45496353..45496379,-#_8e3709ab2117b46ea636dbf54153784bp6@C10orf25
1.88e-21FFCP PHASE1:Hg19::chr3:96336938..96336956,-#_61322040c8f1f0afe737743260dafa15p@chr3:96336938..96336956, -
1.88e-21FFCP PHASE2:Hg19::chr3:96336938..96336956,-#_61322040c8f1f0afe737743260dafa15p@chr3:96336938..96336956, -
2.3e-21FFCP PHASE1:Hg19::chr3:87004049..87004053,-#_8964e1f6be7e7451b3fafb642cfa2179p@chr3:87004049..87004053, -
2.3e-21FFCP PHASE2:Hg19::chr3:87004049..87004053,-#_8964e1f6be7e7451b3fafb642cfa2179p@chr3:87004049..87004053, -
2.82e-21FFCP PHASE1:Hg19::chr12:78359984..78359998,+#_a254cafe5dfbebe839eee5a8cfca6254p19@NAV3
2.82e-21FFCP PHASE2:Hg19::chr1:225962665..225962674,+#_a254cafe5dfbebe839eee5a8cfca6254p@chr1:225962665..225962674, +
2.82e-21FFCP PHASE1:Hg19::chr1:225962665..225962674,+#_a254cafe5dfbebe839eee5a8cfca6254p@chr1:225962665..225962674, +
2.82e-21FFCP PHASE2:Hg19::chr12:78359984..78359998,+#_a254cafe5dfbebe839eee5a8cfca6254p19@NAV3
5.16e-21FFCP PHASE2:Hg19::chr11:503354..503369,+#_22f7a49134497c72c8da35d51326160fp@chr11:503354..503369, +
5.16e-21FFCP PHASE1:Hg19::chr11:503354..503369,+#_22f7a49134497c72c8da35d51326160fp@chr11:503354..503369, +
1.08e-19FFCP PHASE1:Hg19::chr12:78359999..78360035,+#_9536e148840e35d4ec3dec1c66aba727p13@NAV3
1.08e-19FFCP PHASE2:Hg19::chr12:78359999..78360035,+#_9536e148840e35d4ec3dec1c66aba727p13@NAV3
1.3e-19FFCP PHASE1:Hg19::chr3:138666029..138666038,-#_59d1c68e3a0bc5bac8a320a230e85943p8@FOXL2
1.3e-19FFCP PHASE2:Hg19::chr3:138666029..138666038,-#_59d1c68e3a0bc5bac8a320a230e85943p8@FOXL2
2.25e-19FFCP PHASE2:Hg19::chr1:185880819..185880830,+#_1f53ff1f7955573a4340fdabac3810ddp@chr1:185880819..185880830, +
2.25e-19FFCP PHASE1:Hg19::chr1:185880819..185880830,+#_1f53ff1f7955573a4340fdabac3810ddp@chr1:185880819..185880830, +
2.71e-19FFCP PHASE2:Hg19::chr3:69442476..69442481,-#_94b91dad1e21c6d82ef6b3a76b09452cp@chr3:69442476..69442481, -
2.71e-19FFCP PHASE1:Hg19::chr15:80843472..80843480,+#_94b91dad1e21c6d82ef6b3a76b09452cp22@ARNT2
2.71e-19FFCP PHASE1:Hg19::chr4:40848340..40848344,-#_94b91dad1e21c6d82ef6b3a76b09452cp@chr4:40848340..40848344, -
2.71e-19FFCP PHASE2:Hg19::chr15:80843472..80843480,+#_94b91dad1e21c6d82ef6b3a76b09452cp22@ARNT2
2.71e-19FFCP PHASE2:Hg19::chr4:40848340..40848344,-#_94b91dad1e21c6d82ef6b3a76b09452cp@chr4:40848340..40848344, -
2.71e-19FFCP PHASE1:Hg19::chr10:47081891..47081936,+#_94b91dad1e21c6d82ef6b3a76b09452cp@chr10:47081891..47081936, +
2.71e-19FFCP PHASE1:Hg19::chr3:69442476..69442481,-#_94b91dad1e21c6d82ef6b3a76b09452cp@chr3:69442476..69442481, -
2.71e-19FFCP PHASE1:Hg19::chr13:45694574..45694578,+#_94b91dad1e21c6d82ef6b3a76b09452cp6@GTF2F2
2.71e-19FFCP PHASE2:Hg19::chr10:47081891..47081936,+#_94b91dad1e21c6d82ef6b3a76b09452cp@chr10:47081891..47081936, +
2.71e-19FFCP PHASE2:Hg19::chr13:45694574..45694578,+#_94b91dad1e21c6d82ef6b3a76b09452cp6@GTF2F2
3.25e-19FFCP PHASE2:Hg19::chr18:10979606..10979617,-#_5293471b760ade75302e04a22243af10p@chr18:10979606..10979617, -
3.25e-19FFCP PHASE1:Hg19::chr18:10979606..10979617,-#_5293471b760ade75302e04a22243af10p@chr18:10979606..10979617, -
4.69e-19FFCP PHASE1:Hg19::chr11:29450724..29450728,+#_fee80a739370e28a61a74ef03424c40dp@chr11:29450724..29450728, +
4.69e-19FFCP PHASE2:Hg19::chr11:29450724..29450728,+#_fee80a739370e28a61a74ef03424c40dp@chr11:29450724..29450728, +
5.26e-18FFCP PHASE2:Hg19::chr1:186159161..186159177,+#_a19d685480a2a73291e40c0bb9202a58p@chr1:186159161..186159177, +
5.26e-18FFCP PHASE1:Hg19::chr1:186159161..186159177,+#_a19d685480a2a73291e40c0bb9202a58p@chr1:186159161..186159177, +
6.23e-18FFCP PHASE1:Hg19::chr3:197640146..197640157,-#_2ec75ad8bc706e09da056a73346f9f21p7@IQCG
6.23e-18FFCP PHASE1:Hg19::chr15:74220226..74220237,-#_2ec75ad8bc706e09da056a73346f9f21p6@LOC100287616
6.23e-18FFCP PHASE2:Hg19::chr15:74220226..74220237,-#_2ec75ad8bc706e09da056a73346f9f21p6@LOC100287616
6.23e-18FFCP PHASE2:Hg19::chr3:197640146..197640157,-#_2ec75ad8bc706e09da056a73346f9f21p7@IQCG
7.37e-18FFCP PHASE2:Hg19::chr5:14231969..14231971,+#_8d371027c5c301237df502775656f309p@chr5:14231969..14231971, +
7.37e-18FFCP PHASE2:Hg19::chr20:2795626..2795639,+#_8d371027c5c301237df502775656f309p1@C20orf141, p1@TMEM239
7.37e-18FFCP PHASE1:Hg19::chr5:14231969..14231971,+#_8d371027c5c301237df502775656f309p@chr5:14231969..14231971, +
7.37e-18FFCP PHASE1:Hg19::chr20:2795626..2795639,+#_8d371027c5c301237df502775656f309p1@C20orf141, p1@TMEM239
1.03e-17FFCP PHASE2:Hg19::chr7:45928011..45928026,+#_a9560aa145c3a1dd05bf9f1f01a38f82p4@IGFBP1
1.03e-17FFCP PHASE1:Hg19::chr7:45928011..45928026,+#_a9560aa145c3a1dd05bf9f1f01a38f82p4@IGFBP1
1.22e-17FFCP PHASE2:Hg19::chr3:138666453..138666470,+#_143e3b8de90c9e28ab99e4b6664718eap4@C3orf72
1.22e-17FFCP PHASE1:Hg19::chr3:138666453..138666470,+#_143e3b8de90c9e28ab99e4b6664718eap4@C3orf72
1.04e-16FFCP PHASE1:Hg19::chr8:103367355..103367356,-#_10f6f5068c3ce0361bb3c8a5a46dca0ep@chr8:103367355..103367356, -
1.04e-16FFCP PHASE2:Hg19::chr2:49381646..49381667,-#_10f6f5068c3ce0361bb3c8a5a46dca0ep1@FSHR

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