CL:0001029: Difference between revisions
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|name=common dendritic progenitor | |name=common dendritic progenitor | ||
|namespace= | |namespace=FANTOM | ||
|obo_creation_date= | |obo_creation_date= | ||
|part_of= | |part_of= | ||
Latest revision as of 16:39, 12 September 2014
| Name: | common dendritic progenitor |
|---|---|
| Namespace: | FANTOM |
| Definition: | "Common dendritic precursor is a hematopoietic progenitor cell that is CD117-low, CD135-positive, CD115-positive and lacks plasma membrane parts for hematopoietic lineage markers." [GO_REF:0000031, GOC:amm, GOC:tfm, PMID:16551251, PMID:17922016, PMID:19286519] |
| Synonyms: |
"CDP" EXACT [PMID:21219184] "common dendritic precursor" EXACT [] "pro-DCs" EXACT [PMID:21219184] |
| Comments: | Surface markers are for mouse cells. Originally described in the dendritic cell ontology (DC_CL:0000041) CDP are reportedly CD2-negative, CD3-negative, CD4-negative, CD5-negative, CD8a-negative, CD11c-positive, CD14-negative, CD19-negative, CD20-negative, CD56-negative, B220-negative, Ly6g-negative, MHCII-positive, and Ter119-negative. (PMID: 19243617). |
Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data
Parents
| is_a: | CL:0000763(myeloid cell),CL:0001019(CD115-positive monocyte OR common dendritic progenitor) |
|---|---|
| develops_from: | CL:0002009(macrophage dendritic cell progenitor) |
Children
| develops from: | CL:0000840 (immature conventional dendritic cell) |
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Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.
Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0001029 (common dendritic progenitor), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data
