MCL coexpression mm9:1082

Phase1 CAGE Peaks

	Short description
Mm9::chr11:60590743..60590786,-	p1@Top3a
Mm9::chr14:52816857..52816882,-	p2@LOC100505120 p2@Supt16h
Mm9::chr1:180267837..180267864,-	p2@Hnrnpu
Mm9::chr3:88101118..88101140,+	p3@Cct3
Mm9::chr4:124392053..124392123,+	p1@Sf3a3
Mm9::chr4:98590599..98590667,+	p1@Usp1
Mm9::chr7:34953535..34953601,-	p1@Uba2

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0006260	DNA replication	0.0296968162132516
GO:0006259	DNA metabolic process	0.0296968162132516
GO:0003917	DNA topoisomerase type I activity	0.0296968162132516
GO:0006281	DNA repair	0.0296968162132516
GO:0005832	chaperonin-containing T-complex	0.0296968162132516
GO:0008641	small protein activating enzyme activity	0.0296968162132516
GO:0003916	DNA topoisomerase activity	0.0296968162132516
GO:0006974	response to DNA damage stimulus	0.0296968162132516
GO:0043170	macromolecule metabolic process	0.0296968162132516
GO:0006265	DNA topological change	0.0296968162132516
GO:0032392	DNA geometric change	0.0296968162132516
GO:0006268	DNA unwinding during replication	0.0296968162132516
GO:0032508	DNA duplex unwinding	0.0296968162132516
GO:0009719	response to endogenous stimulus	0.0299976368010458
GO:0044424	intracellular part	0.0330601004047649
GO:0005622	intracellular	0.0393223373439133
GO:0006304	DNA modification	0.0402409540760293
GO:0044238	primary metabolic process	0.0402409540760293
GO:0044237	cellular metabolic process	0.0402409540760293
GO:0005694	chromosome	0.0402409540760293
GO:0043283	biopolymer metabolic process	0.0402409540760293

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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