MCL coexpression mm9:1579

Phase1 CAGE Peaks

	Short description
Mm9::chr11:69468501..69468515,+	p2@Sox15
Mm9::chr11:69468531..69468557,+	p1@Sox15
Mm9::chr11:69469086..69469110,+	p@chr11:69469086..69469110 +
Mm9::chr11:69469119..69469132,+	p@chr11:69469119..69469132 +
Mm9::chr1:132783985..132783998,-	p1@Il24

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0043403	skeletal muscle regeneration	0.0199032225028654
GO:0009008	DNA-methyltransferase activity	0.0199032225028654
GO:0003886	DNA (cytosine-5-)-methyltransferase activity	0.0199032225028654
GO:0045843	negative regulation of striated muscle development	0.0208972385110975
GO:0031099	regeneration	0.0218899458142884
GO:0042246	tissue regeneration	0.0218899458142884
GO:0016202	regulation of striated muscle development	0.0221730155987539
GO:0048627	myoblast development	0.0328250216395579
GO:0045445	myoblast differentiation	0.0477271641505972

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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