DOID:120

Name:	female reproductve organ cancer
Namespace:	disease_ontology
Definition:	"A reproductive organ cancer that is manifested in the female genitals. This includes organs such as the ovaries, fallopian tubes, uterus, cervix, vagina and vulva." [url:http\://en.wikipedia.org/wiki/Template\:Female_genital_neoplasia, url:http\://www.wrongdiagnosis.com/g/genital_system_cancer/intro.htm]
Xrefs:	Expandlinks: MSH:D005833 NCI:C3053 SNOMEDCT_2010_1_31:126907002 SNOMEDCT_2010_1_31:188207007 UMLS_CUI:C0017416 UMLS_CUI:C0153585 UMLS_CUI:C0699889
Synonyms:	"female reproductive cancer" EXACT [] "malignant Gynecologic tumor" EXACT [NCI2004_11_17:C4913] "malignant neoplasm of female genital organ" EXACT []
Alt_id:	DOID:1244 DOID:1281

Ontology association<br>Each term has an is_a parent in the Disease Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to DISEASE ontologies.<br><br>link to ontology dataset<br>data

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Parents

is_a:	DOID:193(reproductive organ cancer)

Children

is a:	DOID:2021 (placenta cancer),DOID:2394 (ovarian cancer),DOID:3001 (female reproductive endometrioid cancer),DOID:363 (uterine cancer),DOID:4362 (cervical cancer)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples

Human (Homo sapiens)

• 10431-106D8 (epidermoid carcinoma cell line:Ca Ski)
• 10448-106F7 (endometrial stromal sarcoma cell line:OMC-9)
• 10497-107C2 (endometrial carcinoma cell line:OMC-2)
• 10530-107F8
• 10552-107I3 (cervical cancer cell line:D98-AH2)
• 10553-107I4 (cervical cancer cell line:ME-180)
• 10589-108D4 (argyrophil small cell carcinoma cell line:TC-YIK)
• 10598-108E4
• 10623-108H2
• 10636-108I6 (clear cell carcinoma cell line:TEN)

... further results Mouse (Mus musculus)

• 10431-106D8 (epidermoid carcinoma cell line:Ca Ski)
• 10448-106F7 (endometrial stromal sarcoma cell line:OMC-9)
• 10497-107C2 (endometrial carcinoma cell line:OMC-2)
• 10530-107F8
• 10552-107I3 (cervical cancer cell line:D98-AH2)
• 10553-107I4 (cervical cancer cell line:ME-180)
• 10589-108D4 (argyrophil small cell carcinoma cell line:TC-YIK)
• 10598-108E4
• 10623-108H2
• 10636-108I6 (clear cell carcinoma cell line:TEN)

... further results

Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with DOID:120 (female reproductve organ cancer), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

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P-value	FFCP	Short description

P-value	FFCP	Short description
3.65e-39	FFCP PHASE1:Hg19::chr5:136482422..136482426,+	p@chr5:136482422..136482426, +
3.65e-39	FFCP PHASE2:Hg19::chr5:136482422..136482426,+	p@chr5:136482422..136482426, +
2.16e-37	FFCP PHASE2:Hg19::chr4:90332316..90332323,+	p@chr4:90332316..90332323, +
2.16e-37	FFCP PHASE1:Hg19::chr4:90332316..90332323,+	p@chr4:90332316..90332323, +
2.6e-36	FFCP PHASE2:Hg19::chr5:81654563..81654582,+	p@chr5:81654563..81654582, +
2.6e-36	FFCP PHASE1:Hg19::chr5:81654563..81654582,+	p@chr5:81654563..81654582, +
9.43e-34	FFCP PHASE2:Hg19::chr16:88278862..88278869,-	p@chr16:88278862..88278869, -
9.43e-34	FFCP PHASE1:Hg19::chr16:88278862..88278869,-	p@chr16:88278862..88278869, -
1.17e-32	FFCP PHASE2:Hg19::chr4:118247051..118247056,+	p@chr4:118247051..118247056, +
1.17e-32	FFCP PHASE1:Hg19::chr4:118247051..118247056,+	p@chr4:118247051..118247056, +
2.36e-32	FFCP PHASE1:Hg19::chr1:9262795..9262800,-	p3@ENST00000437157
2.36e-32	FFCP PHASE2:Hg19::chr1:9262795..9262800,-	p3@ENST00000437157
2.85e-32	FFCP PHASE1:Hg19::chr2:113981834..113981850,-	p@chr2:113981834..113981850, -
2.85e-32	FFCP PHASE2:Hg19::chr2:113981834..113981850,-	p@chr2:113981834..113981850, -
7.1e-31	FFCP PHASE1:Hg19::chr1:98206661..98206672,-	p@chr1:98206661..98206672, -
7.1e-31	FFCP PHASE2:Hg19::chr1:98206661..98206672,-	p@chr1:98206661..98206672, -
7.55e-31	FFCP PHASE2:Hg19::chr6:75178505..75178516,+	p@chr6:75178505..75178516, +
7.55e-31	FFCP PHASE1:Hg19::chr6:75178505..75178516,+	p@chr6:75178505..75178516, +
1.02e-30	FFCP PHASE1:Hg19::chr3:45152138..45152151,-	p5@CDCP1
1.02e-30	FFCP PHASE2:Hg19::chr3:45152138..45152151,-	p5@CDCP1
5.44e-30	FFCP PHASE1:Hg19::chr18:25694851..25694855,-	p@chr18:25694851..25694855, -
5.44e-30	FFCP PHASE2:Hg19::chr18:25694851..25694855,-	p@chr18:25694851..25694855, -
2.95e-29	FFCP PHASE2:Hg19::chr5:81654586..81654599,+	p@chr5:81654586..81654599, +
2.95e-29	FFCP PHASE1:Hg19::chr5:81654586..81654599,+	p@chr5:81654586..81654599, +
6.21e-29	FFCP PHASE2:Hg19::chr14:62024238..62024249,+	p@chr14:62024238..62024249, +
6.21e-29	FFCP PHASE1:Hg19::chr14:62024238..62024249,+	p@chr14:62024238..62024249, +
2.34e-28	FFCP PHASE2:Hg19::chr9:6257179..6257191,+	p@chr9:6257179..6257191, +
2.34e-28	FFCP PHASE1:Hg19::chr9:6257179..6257191,+	p@chr9:6257179..6257191, +
8.67e-28	FFCP PHASE2:Hg19::chr18:53169326..53169330,-	p@chr18:53169326..53169330, -
8.67e-28	FFCP PHASE1:Hg19::chr18:53169326..53169330,-	p@chr18:53169326..53169330, -
9.15e-27	FFCP PHASE2:Hg19::chr4:167068286..167068320,+	p@chr4:167068286..167068320, +
9.15e-27	FFCP PHASE1:Hg19::chr4:167068286..167068320,+	p@chr4:167068286..167068320, +
1.8e-26	FFCP PHASE1:Hg19::chr1:222079924..222079927,-	p@chr1:222079924..222079927, -
1.8e-26	FFCP PHASE2:Hg19::chr1:222079924..222079927,-	p@chr1:222079924..222079927, -
3.38e-26	FFCP PHASE2:Hg19::chr4:38143865..38143904,-	p@chr4:38143865..38143904, -
3.38e-26	FFCP PHASE1:Hg19::chr4:38143865..38143904,-	p@chr4:38143865..38143904, -
3.9e-25	FFCP PHASE1:Hg19::chr6:14671928..14671958,+	p@chr6:14671928..14671958, +
3.9e-25	FFCP PHASE2:Hg19::chr6:14671928..14671958,+	p@chr6:14671928..14671958, +
5.11e-25	FFCP PHASE2:Hg19::chr2:113982635..113982648,-	p8@PAX8
5.11e-25	FFCP PHASE1:Hg19::chr2:113982635..113982648,-	p8@PAX8
4.16e-24	FFCP PHASE1:Hg19::chr6:18497083..18497107,+	p@chr6:18497083..18497107, +
4.16e-24	FFCP PHASE2:Hg19::chr6:18497083..18497107,+	p@chr6:18497083..18497107, +
6.49e-24	FFCP PHASE1:Hg19::chr5:64469134..64469150,-	p@chr5:64469134..64469150, -
6.49e-24	FFCP PHASE2:Hg19::chr5:64469134..64469150,-	p@chr5:64469134..64469150, -
5.98e-23	FFCP PHASE1:Hg19::chr8:101588316..101588317,-	p1@AK127517
5.98e-23	FFCP PHASE2:Hg19::chr6:18496965..18496969,+	p@chr6:18496965..18496969, +
5.98e-23	FFCP PHASE1:Hg19::chr6:42724431..42724435,+	p@chr6:42724431..42724435, +
5.98e-23	FFCP PHASE1:Hg19::chr16:75511082..75511090,+	p@chr16:75511082..75511090, +
5.98e-23	FFCP PHASE2:Hg19::chr7:20257461..20257472,-	p9@MACC1
5.98e-23	FFCP PHASE1:Hg19::chr6:18496965..18496969,+	p@chr6:18496965..18496969, +
5.98e-23	FFCP PHASE2:Hg19::chr8:101588316..101588317,-	p1@AK127517
5.98e-23	FFCP PHASE2:Hg19::chr16:75511082..75511090,+	p@chr16:75511082..75511090, +
5.98e-23	FFCP PHASE2:Hg19::chr6:42724431..42724435,+	p@chr6:42724431..42724435, +
5.98e-23	FFCP PHASE1:Hg19::chr7:20257461..20257472,-	p9@MACC1
1.52e-22	FFCP PHASE2:Hg19::chr5:73109313..73109326,+	p4@RGNEF
1.52e-22	FFCP PHASE1:Hg19::chr5:73109313..73109326,+	p4@RGNEF
5.58e-22	FFCP PHASE1:Hg19::chr2:162931138..162931149,-	p14@DPP4
5.58e-22	FFCP PHASE2:Hg19::chr2:162931138..162931149,-	p14@DPP4
5.86e-22	FFCP PHASE1:Hg19::chr12:127762515..127762539,-	p@chr12:127762515..127762539, -
5.86e-22	FFCP PHASE2:Hg19::chr12:127762515..127762539,-	p@chr12:127762515..127762539, -
7.34e-22	FFCP PHASE2:Hg19::chr9:83566735..83566738,+	p@chr9:83566735..83566738, +
7.34e-22	FFCP PHASE1:Hg19::chr9:83566735..83566738,+	p@chr9:83566735..83566738, +
8.77e-22	FFCP PHASE1:Hg19::chr20:6034672..6034714,-	p2@LRRN4
8.77e-22	FFCP PHASE2:Hg19::chr20:6034672..6034714,-	p2@LRRN4
9.15e-22	FFCP PHASE1:Hg19::chr13:38083855..38083873,+	p@chr13:38083855..38083873, +
9.15e-22	FFCP PHASE2:Hg19::chr13:38083855..38083873,+	p@chr13:38083855..38083873, +
4.75e-21	FFCP PHASE1:Hg19::chr2:113982348..113982371,-	p@chr2:113982348..113982371, -
4.75e-21	FFCP PHASE2:Hg19::chr2:113982348..113982371,-	p@chr2:113982348..113982371, -
6.42e-21	FFCP PHASE1:Hg19::chr3:197639921..197639934,-	p6@IQCG
6.42e-21	FFCP PHASE2:Hg19::chr3:197639921..197639934,-	p6@IQCG
6.46e-21	FFCP PHASE1:Hg19::chr10:28367236..28367266,+	p@chr10:28367236..28367266, +
6.46e-21	FFCP PHASE2:Hg19::chr10:28367236..28367266,+	p@chr10:28367236..28367266, +
1.04e-20	FFCP PHASE2:Hg19::chr22:30640029..30640037,-	p@chr22:30640029..30640037, -
1.04e-20	FFCP PHASE1:Hg19::chr22:30640029..30640037,-	p@chr22:30640029..30640037, -
1.48e-20	FFCP PHASE2:Hg19::chr22:28901919..28901924,+	p@chr22:28901919..28901924, +
1.48e-20	FFCP PHASE2:Hg19::chr7:17409475..17409478,-	p@chr7:17409475..17409478, -
1.48e-20	FFCP PHASE1:Hg19::chr7:17409475..17409478,-	p@chr7:17409475..17409478, -
1.48e-20	FFCP PHASE1:Hg19::chr22:28901919..28901924,+	p@chr22:28901919..28901924, +
1.54e-20	FFCP PHASE2:Hg19::chr17:57841314..57841323,-	p@chr17:57841314..57841323, -
1.54e-20	FFCP PHASE1:Hg19::chr17:57841314..57841323,-	p@chr17:57841314..57841323, -
3.67e-20	FFCP PHASE2:Hg19::chr9:6257148..6257157,+	p@chr9:6257148..6257157, +
3.67e-20	FFCP PHASE1:Hg19::chr9:6257148..6257157,+	p@chr9:6257148..6257157, +
3.9e-20	FFCP PHASE1:Hg19::chr16:34980938..34980966,+	p1@FLJ26245
3.9e-20	FFCP PHASE2:Hg19::chr16:34980938..34980966,+	p1@FLJ26245
3.9e-20	FFCP PHASE1:Hg19::chr16:34980881..34980902,+	p1@ENST00000516136
3.9e-20	FFCP PHASE2:Hg19::chr16:34980881..34980902,+	p1@ENST00000516136
4.2e-20	FFCP PHASE1:Hg19::chr9:118435168..118435186,+	p@chr9:118435168..118435186, +
4.2e-20	FFCP PHASE2:Hg19::chr9:118435168..118435186,+	p@chr9:118435168..118435186, +
7.09e-20	FFCP PHASE1:Hg19::chr2:113990903..113990907,-	p@chr2:113990903..113990907, -
7.09e-20	FFCP PHASE2:Hg19::chr2:113990903..113990907,-	p@chr2:113990903..113990907, -
8.46e-20	FFCP PHASE1:Hg19::chr10:4284210..4284228,+	p@chr10:4284210..4284228, +
8.46e-20	FFCP PHASE2:Hg19::chr10:4284210..4284228,+	p@chr10:4284210..4284228, +
1.04e-19	FFCP PHASE2:Hg19::chr8:38008450..38008459,-	p4@STAR
1.04e-19	FFCP PHASE1:Hg19::chr8:38008450..38008459,-	p4@STAR
1.89e-19	FFCP PHASE1:Hg19::chr9:5621474..5621483,-	p@chr9:5621474..5621483, -
1.89e-19	FFCP PHASE2:Hg19::chr9:5621474..5621483,-	p@chr9:5621474..5621483, -
2.1e-19	FFCP PHASE1:Hg19::chr2:114036488..114036504,-	p1@PAX8
2.1e-19	FFCP PHASE2:Hg19::chr2:114036488..114036504,-	p1@PAX8
4.93e-19	FFCP PHASE2:Hg19::chr2:1048832..1048860,+	p@chr2:1048832..1048860, +
4.93e-19	FFCP PHASE1:Hg19::chr2:1048832..1048860,+	p@chr2:1048832..1048860, +

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