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UBERON:0002418

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Name:cartilage tissue
Definition:"Skeletal tissue that is avascular, rich in glycosaminoglycans (GAGs) and typically includes chondrocytes within isolated lacunae. Cartilage tissue is deposited by chondroblasts[VSAO]." VSAO:0000040, Wikipedia:Cartilage
Xrefs:
links:

AAO:0000060
AEO:0000087
BTO:0000206
EFO:0000949
EHDAA2:0003087
EV:0100141
FMA:37377
GAID:99
galen:Cartilage
[1]
MA:0000104
MAT:0000189
MESH:A.02.165
MIAA:0000189
ncithesaurus:Cartilage
OpenCyc:Mx4rvVjeOZwpEbGdrcN5Y29ycA
SCTID:309312004
TAO:0001501
VHOG:0001207
VSAO:0000040
XAO:0000170

ZFA:0005622
Synonyms: "cartilage tissue" EXACT [FMA:37377]
"cartilaginous tissue" EXACT []
Comments:Previous: "A portion of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate[GO]. Regular connective tissue, which consists of chondrocytes and related cells, the intercellular matrix of which is chondrified. Examples: hyaline cartilage, fibrocartilage, elastic cartilage[FMA]. an avascular supporting and articular skeletal tissue. It also functions as the primary endoskeletal support in vertebrate embryos. Cartilage is deposited by and is composed of chondroblasts and chondrocytes separated by an extracellular matrix, which may or may not mineralize depending on cartilage type, age, or taxon[Hall and Witten]." See also FMA:71500 Set of cartilages, FMA:55107 Cartilage organ, FMA:12264 Articular cartilage. // elements made from cartilage, cartilage-like, or chondroid tissues evolved in invertebrates[H&W]
Alt_id: UBERON:MA_0000104-MIAA_0000189-XAO_0000170
Subset: uberon_slim
vertebrate_core

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:UBERON:0004755(skeletal tissue)



Children

is a:UBERON:0001995 (fibrocartilage)
derives from:FF:0101574 (chondrosarcoma cell line sample)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology

Human (Homo sapiens)


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0002418 (cartilage tissue), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
1.71e-66FFCP PHASE2:Hg19::chr1:78769549..78769554,+#_dfacfed871cb9c9ae756e3f67d0137aep5@PTGFR
1.71e-66FFCP PHASE1:Hg19::chr1:78769549..78769554,+#_dfacfed871cb9c9ae756e3f67d0137aep5@PTGFR
2.39e-66FFCP PHASE2:Hg19::chrX:135338329..135338337,-#_692c0263db1d68576fc64eaecd1f9d96p@chrX:135338329..135338337, -
2.39e-66FFCP PHASE2:Hg19::chr13:23733607..23733611,-#_692c0263db1d68576fc64eaecd1f9d96p@chr13:23733607..23733611, -
2.39e-66FFCP PHASE1:Hg19::chr6:152590257..152590288,-#_692c0263db1d68576fc64eaecd1f9d96p@chr6:152590257..152590288, -
2.39e-66FFCP PHASE1:Hg19::chr1:228806586..228806591,+#_692c0263db1d68576fc64eaecd1f9d96p@chr1:228806586..228806591, +
2.39e-66FFCP PHASE2:Hg19::chr9:13006722..13006729,-#_692c0263db1d68576fc64eaecd1f9d96p@chr9:13006722..13006729, -
2.39e-66FFCP PHASE2:Hg19::chr3:99508248..99508255,-#_692c0263db1d68576fc64eaecd1f9d96p@chr3:99508248..99508255, -
2.39e-66FFCP PHASE2:Hg19::chr18:22251696..22251702,-#_692c0263db1d68576fc64eaecd1f9d96p@chr18:22251696..22251702, -
2.39e-66FFCP PHASE2:Hg19::chr7:79999046..79999051,+#_692c0263db1d68576fc64eaecd1f9d96p41@CD36
2.39e-66FFCP PHASE2:Hg19::chr6:150735014..150735021,-#_692c0263db1d68576fc64eaecd1f9d96p@chr6:150735014..150735021, -
2.39e-66FFCP PHASE2:Hg19::chr1:197886803..197886812,+#_692c0263db1d68576fc64eaecd1f9d96p7@LHX9
2.39e-66FFCP PHASE2:Hg19::chr12:71031372..71031377,-#_692c0263db1d68576fc64eaecd1f9d96p25@PTPRB
2.39e-66FFCP PHASE2:Hg19::chr3:1577545..1577547,-#_692c0263db1d68576fc64eaecd1f9d96p@chr3:1577545..1577547, -
2.39e-66FFCP PHASE2:Hg19::chr18:74535888..74535894,-#_692c0263db1d68576fc64eaecd1f9d96p@chr18:74535888..74535894, -
2.39e-66FFCP PHASE2:Hg19::chr14:88338702..88338713,-#_692c0263db1d68576fc64eaecd1f9d96p1@ENST00000554305
2.39e-66FFCP PHASE1:Hg19::chr3:127441545..127441550,-#_692c0263db1d68576fc64eaecd1f9d96p58@MGLL
2.39e-66FFCP PHASE1:Hg19::chr12:71031372..71031377,-#_692c0263db1d68576fc64eaecd1f9d96p25@PTPRB
2.39e-66FFCP PHASE2:Hg19::chr13:23169005..23169009,+#_692c0263db1d68576fc64eaecd1f9d96p@chr13:23169005..23169009, +
2.39e-66FFCP PHASE1:Hg19::chr18:74961699..74961708,+#_692c0263db1d68576fc64eaecd1f9d96p5@GALR1
2.39e-66FFCP PHASE1:Hg19::chr11:30105969..30105977,-#_692c0263db1d68576fc64eaecd1f9d96p1@ENST00000527819
2.39e-66FFCP PHASE2:Hg19::chr3:2141813..2141822,-#_692c0263db1d68576fc64eaecd1f9d96p@chr3:2141813..2141822, -
2.39e-66FFCP PHASE2:Hg19::chr1:145473286..145473295,+#_692c0263db1d68576fc64eaecd1f9d96p5@AB464458
2.39e-66FFCP PHASE2:Hg19::chr3:30570717..30570723,-#_692c0263db1d68576fc64eaecd1f9d96p@chr3:30570717..30570723, -
2.39e-66FFCP PHASE2:Hg19::chr1:192408018..192408032,-#_692c0263db1d68576fc64eaecd1f9d96p@chr1:192408018..192408032, -
2.39e-66FFCP PHASE2:Hg19::chr10:54786954..54786965,-#_692c0263db1d68576fc64eaecd1f9d96p@chr10:54786954..54786965, -
2.39e-66FFCP PHASE2:Hg19::chr6:152590052..152590068,-#_692c0263db1d68576fc64eaecd1f9d96p@chr6:152590052..152590068, -
2.39e-66FFCP PHASE1:Hg19::chr4:139817573..139817580,-#_692c0263db1d68576fc64eaecd1f9d96p@chr4:139817573..139817580, -
2.39e-66FFCP PHASE2:Hg19::chr16:52581957..52581960,-#_692c0263db1d68576fc64eaecd1f9d96p8@TOX3
2.39e-66FFCP PHASE1:Hg19::chr3:163194047..163194081,-#_692c0263db1d68576fc64eaecd1f9d96p@chr3:163194047..163194081, -
2.39e-66FFCP PHASE1:Hg19::chr2:188420455..188420469,+#_692c0263db1d68576fc64eaecd1f9d96p@chr2:188420455..188420469, +
2.39e-66FFCP PHASE2:Hg19::chr12:80818234..80818245,+#_692c0263db1d68576fc64eaecd1f9d96p@chr12:80818234..80818245, +
2.39e-66FFCP PHASE2:Hg19::chr3:2141888..2141892,-#_692c0263db1d68576fc64eaecd1f9d96p@chr3:2141888..2141892, -
2.39e-66FFCP PHASE2:Hg19::chr5:39548606..39548614,-#_692c0263db1d68576fc64eaecd1f9d96p@chr5:39548606..39548614, -
2.39e-66FFCP PHASE2:Hg19::chr1:172009977..172009985,+#_692c0263db1d68576fc64eaecd1f9d96p@chr1:172009977..172009985, +
2.39e-66FFCP PHASE1:Hg19::chr3:2141982..2141990,+#_692c0263db1d68576fc64eaecd1f9d96p16@CNTN4
2.39e-66FFCP PHASE2:Hg19::chr3:157206082..157206087,-#_692c0263db1d68576fc64eaecd1f9d96p@chr3:157206082..157206087, -
2.39e-66FFCP PHASE2:Hg19::chr6:152589245..152589256,-#_692c0263db1d68576fc64eaecd1f9d96p53@SYNE1
2.39e-66FFCP PHASE2:Hg19::chr1:197890538..197890548,+#_692c0263db1d68576fc64eaecd1f9d96p@chr1:197890538..197890548, +
2.39e-66FFCP PHASE1:Hg19::chr1:192407879..192407891,-#_692c0263db1d68576fc64eaecd1f9d96p@chr1:192407879..192407891, -
2.39e-66FFCP PHASE1:Hg19::chr10:63700076..63700086,+#_692c0263db1d68576fc64eaecd1f9d96p@chr10:63700076..63700086, +
2.39e-66FFCP PHASE2:Hg19::chr19:41281630..41281644,+#_692c0263db1d68576fc64eaecd1f9d96p6@RAB4B
2.39e-66FFCP PHASE1:Hg19::chr3:157230599..157230604,+#_692c0263db1d68576fc64eaecd1f9d96p@chr3:157230599..157230604, +
2.39e-66FFCP PHASE2:Hg19::chr13:23734279..23734283,+#_692c0263db1d68576fc64eaecd1f9d96p@chr13:23734279..23734283, +
2.39e-66FFCP PHASE1:Hg19::chr6:152792957..152792960,-#_692c0263db1d68576fc64eaecd1f9d96p@chr6:152792957..152792960, -
2.39e-66FFCP PHASE1:Hg19::chr3:2141759..2141771,-#_692c0263db1d68576fc64eaecd1f9d96p@chr3:2141759..2141771, -
2.39e-66FFCP PHASE1:Hg19::chr13:24914614..24914622,-#_692c0263db1d68576fc64eaecd1f9d96p@chr13:24914614..24914622, -
2.39e-66FFCP PHASE2:Hg19::chr3:127441501..127441504,-#_692c0263db1d68576fc64eaecd1f9d96p59@MGLL
2.39e-66FFCP PHASE2:Hg19::chr4:169935479..169935481,-#_692c0263db1d68576fc64eaecd1f9d96p@chr4:169935479..169935481, -
2.39e-66FFCP PHASE1:Hg19::chr14:83319766..83319776,-#_692c0263db1d68576fc64eaecd1f9d96p@chr14:83319766..83319776, -
2.39e-66FFCP PHASE1:Hg19::chr6:152589396..152589401,-#_692c0263db1d68576fc64eaecd1f9d96p68@SYNE1
2.39e-66FFCP PHASE1:Hg19::chr1:198595896..198595910,+#_692c0263db1d68576fc64eaecd1f9d96p@chr1:198595896..198595910, +
2.39e-66FFCP PHASE1:Hg19::chr11:30253410..30253431,+#_692c0263db1d68576fc64eaecd1f9d96p2@FSHB
2.39e-66FFCP PHASE2:Hg19::chr5:128083931..128083952,+#_692c0263db1d68576fc64eaecd1f9d96p@chr5:128083931..128083952, +
2.39e-66FFCP PHASE2:Hg19::chr17:46178195..46178202,-#_692c0263db1d68576fc64eaecd1f9d96p12@CBX1
2.39e-66FFCP PHASE1:Hg19::chr3:2140149..2140157,+#_692c0263db1d68576fc64eaecd1f9d96p25@CNTN4
2.39e-66FFCP PHASE2:Hg19::chr6:142993137..142993142,+#_692c0263db1d68576fc64eaecd1f9d96p@chr6:142993137..142993142, +
2.39e-66FFCP PHASE2:Hg19::chr1:197873492..197873502,-#_692c0263db1d68576fc64eaecd1f9d96p@chr1:197873492..197873502, -
2.39e-66FFCP PHASE2:Hg19::chr10:63700043..63700053,+#_692c0263db1d68576fc64eaecd1f9d96p@chr10:63700043..63700053, +
2.39e-66FFCP PHASE1:Hg19::chr10:33244345..33244348,-#_692c0263db1d68576fc64eaecd1f9d96p@chr10:33244345..33244348, -
2.39e-66FFCP PHASE2:Hg19::chr14:88282738..88282741,-#_692c0263db1d68576fc64eaecd1f9d96p1@ENST00000554519
2.39e-66FFCP PHASE2:Hg19::chr13:23027882..23027888,+#_692c0263db1d68576fc64eaecd1f9d96p@chr13:23027882..23027888, +
2.39e-66FFCP PHASE2:Hg19::chr11:30252646..30252648,+#_692c0263db1d68576fc64eaecd1f9d96p@chr11:30252646..30252648, +
2.39e-66FFCP PHASE1:Hg19::chr6:150735340..150735361,+#_692c0263db1d68576fc64eaecd1f9d96p@chr6:150735340..150735361, +
2.39e-66FFCP PHASE2:Hg19::chrX:591202..591211,-#_692c0263db1d68576fc64eaecd1f9d96p@chrX:591202..591211, -
2.39e-66FFCP PHASE2:Hg19::chr3:2141746..2141758,-#_692c0263db1d68576fc64eaecd1f9d96p@chr3:2141746..2141758, -
2.39e-66FFCP PHASE1:Hg19::chr3:177555440..177555446,-#_692c0263db1d68576fc64eaecd1f9d96p@chr3:177555440..177555446, -
2.39e-66FFCP PHASE1:Hg19::chr2:190023542..190023552,-#_692c0263db1d68576fc64eaecd1f9d96p@chr2:190023542..190023552, -
2.39e-66FFCP PHASE1:Hg19::chr15:96181408..96181419,-#_692c0263db1d68576fc64eaecd1f9d96p@chr15:96181408..96181419, -
2.39e-66FFCP PHASE2:Hg19::chr12:70351971..70351975,+#_692c0263db1d68576fc64eaecd1f9d96p@chr12:70351971..70351975, +
2.39e-66FFCP PHASE2:Hg19::chr10:33244302..33244305,-#_692c0263db1d68576fc64eaecd1f9d96p@chr10:33244302..33244305, -
2.39e-66FFCP PHASE1:Hg19::chr3:30442082..30442087,-#_692c0263db1d68576fc64eaecd1f9d96p@chr3:30442082..30442087, -
2.39e-66FFCP PHASE1:Hg19::chr1:154942216..154942223,-#_692c0263db1d68576fc64eaecd1f9d96p@chr1:154942216..154942223, -
2.39e-66FFCP PHASE2:Hg19::chr4:145101707..145101712,+#_692c0263db1d68576fc64eaecd1f9d96p@chr4:145101707..145101712, +
2.39e-66FFCP PHASE2:Hg19::chr3:157230582..157230593,+#_692c0263db1d68576fc64eaecd1f9d96p@chr3:157230582..157230593, +
2.39e-66FFCP PHASE2:Hg19::chr2:175614951..175614956,-#_692c0263db1d68576fc64eaecd1f9d96p@chr2:175614951..175614956, -
2.39e-66FFCP PHASE2:Hg19::chr1:198595872..198595878,+#_692c0263db1d68576fc64eaecd1f9d96p@chr1:198595872..198595878, +
2.39e-66FFCP PHASE2:Hg19::chr19:56047669..56047674,-#_692c0263db1d68576fc64eaecd1f9d96p7@SBK2
2.39e-66FFCP PHASE1:Hg19::chr8:107074411..107074421,+#_692c0263db1d68576fc64eaecd1f9d96p@chr8:107074411..107074421, +
2.39e-66FFCP PHASE1:Hg19::chr3:1577586..1577600,-#_692c0263db1d68576fc64eaecd1f9d96p@chr3:1577586..1577600, -
2.39e-66FFCP PHASE1:Hg19::chr2:175629357..175629367,-#_692c0263db1d68576fc64eaecd1f9d96p6@CHRNA1
2.39e-66FFCP PHASE2:Hg19::chr7:18439523..18439524,+#_692c0263db1d68576fc64eaecd1f9d96p@chr7:18439523..18439524, +
2.39e-66FFCP PHASE1:Hg19::chr3:2141851..2141858,-#_692c0263db1d68576fc64eaecd1f9d96p@chr3:2141851..2141858, -
2.39e-66FFCP PHASE1:Hg19::chr12:70351971..70351975,+#_692c0263db1d68576fc64eaecd1f9d96p@chr12:70351971..70351975, +
2.39e-66FFCP PHASE1:Hg19::chr3:99680705..99680734,+#_692c0263db1d68576fc64eaecd1f9d96p@chr3:99680705..99680734, +
2.39e-66FFCP PHASE2:Hg19::chr15:95751475..95751482,+#_692c0263db1d68576fc64eaecd1f9d96p@chr15:95751475..95751482, +
2.39e-66FFCP PHASE2:Hg19::chr6:96913362..96913393,-#_692c0263db1d68576fc64eaecd1f9d96p@chr6:96913362..96913393, -
2.39e-66FFCP PHASE2:Hg19::chr13:23733790..23733815,-#_692c0263db1d68576fc64eaecd1f9d96p@chr13:23733790..23733815, -
2.39e-66FFCP PHASE2:Hg19::chr1:154942206..154942211,-#_692c0263db1d68576fc64eaecd1f9d96p@chr1:154942206..154942211, -
2.39e-66FFCP PHASE1:Hg19::chr2:53436150..53436154,-#_692c0263db1d68576fc64eaecd1f9d96p@chr2:53436150..53436154, -
2.39e-66FFCP PHASE1:Hg19::chr20:36848135..36848142,-#_692c0263db1d68576fc64eaecd1f9d96p@chr20:36848135..36848142, -
2.39e-66FFCP PHASE2:Hg19::chr6:150735319..150735330,+#_692c0263db1d68576fc64eaecd1f9d96p@chr6:150735319..150735330, +
2.39e-66FFCP PHASE2:Hg19::chr3:1577559..1577577,-#_692c0263db1d68576fc64eaecd1f9d96p@chr3:1577559..1577577, -
2.39e-66FFCP PHASE2:Hg19::chr18:74535969..74535980,-#_692c0263db1d68576fc64eaecd1f9d96p@chr18:74535969..74535980, -
2.39e-66FFCP PHASE1:Hg19::chr6:152589291..152589303,-#_692c0263db1d68576fc64eaecd1f9d96p38@SYNE1
2.39e-66FFCP PHASE2:Hg19::chr1:145473297..145473306,+#_692c0263db1d68576fc64eaecd1f9d96p7@AB464458
2.39e-66FFCP PHASE1:Hg19::chr2:206927652..206927658,-#_692c0263db1d68576fc64eaecd1f9d96p@chr2:206927652..206927658, -
2.39e-66FFCP PHASE1:Hg19::chr13:23368370..23368374,+#_692c0263db1d68576fc64eaecd1f9d96p@chr13:23368370..23368374, +
2.39e-66FFCP PHASE2:Hg19::chr2:74780643..74780673,-#_692c0263db1d68576fc64eaecd1f9d96p30@LOXL3
2.39e-66FFCP PHASE2:Hg19::chr21:38309134..38309135,-#_692c0263db1d68576fc64eaecd1f9d96p@chr21:38309134..38309135, -










Property "Property value" (as page type) with input value "UBPROP:0000001 "A type of dense connective tissue. It is composed of cells called chondrocytes which are dispersed in a firm gel-like ground substance, called the matrix. Cartilage is avascular (contains no blood vessels) and nutrients are diffused through the matrix. Cartilage is found in the joints, the rib cage, the ear, the nose, in the throat and between intervertebral disks. It makes up virtually the entire skeleton in chondrichthyes.[AAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process., Property "Property value" (as page type) with input value "UBPROP:0000001 "Portion of tissue which is connective tissue composed of collagen and/or elastin fibers and chondrocytes. Cartilage is avascular and provides both skeletal functions and a framework upon which bone is deposited.[TAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process., Property "Property value" (as page type) with input value "UBPROP:0000001 "Skeletal tissue that is avascular, rich in glycosaminoglycans (GAGs) and typically includes chondrocytes within isolated lacunae. Cartilage tissue is deposited by chondroblasts.[VSAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process., Property "Property value" (as page type) with input value "UBPROP:0000002 "relationship loss: subclass specialized connective tissue (AAO:0000571)[AAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.

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