UBERON:0001782
From FANTOM5_SSTAR
| Name: | pigmented layer of retina | ||
|---|---|---|---|
| Definition: | "A monolayer of pigmented epithelium covering the neural retina; develops from the outer of the two layers of the optic cup[ZFA]. the pigmented cell layer just outside the neurosensory retina that nourishes retinal visual cells, and is firmly attached to the underlying choroid and overlying retinal visual cells[WP]." [Wikipedia:Retinal_pigment_epithelium, ZFIN:curator] | ||
| Xrefs: |
| ||
| Synonyms: |
"epithelium, retinal pigment" RELATED [BTO:0001177] "outer pigmented layer of retina" EXACT [] "pigment epithelium of retina" EXACT [] "pigmented epithelium" RELATED [] "pigmented retina" RELATED [] "pigmented retinal epithelium" EXACT [] "PRE" RELATED [] "retinal pigment epithelium" EXACT [MP:0005201, Wikipedia:Retinal_pigment_epithelium] "retinal pigmented epithelium" EXACT [ZFA:0000144] "RPE" RELATED [] "stratum pigmentosa retinae, p. pigmentosa retinae" RELATED LATIN [Wikipedia:Retinal_pigment_epithelium] "stratum pigmentosum (retina)" EXACT [] | ||
| Comments: | editor note - we follow ontologies such as FMA and ZFA in first dividing into pigmented and neural layers | ||
| Alt_id: | UBERON:FMA_58627-MA_0000279-ZFA_0000144 | ||
| Subset: |
uberon_slim vertebrate_core |
Gray881.png]
200px-Gray881.png]
Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data
Parents
| is_a: | UBERON:0001781(layer of retina),UBERON:0007625(pigment epithelium of eye),UBERON:0010371(ecto-epithelium) |
|---|---|
| develops_from: | UBERON:0005424(presumptive retinal pigmented epithelium) |
Children
| part of: | CL:0002586 (retinal pigment epithelial cell) |
|---|
Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology
Human (Homo sapiens)
- 11215-116A9 (Retinal Pigment Epithelial Cells, donor0)
- 11528-119I7 (Retinal Pigment Epithelial Cells, donor1)
- 11608-120I6 (Retinal Pigment Epithelial Cells, donor2)
- 11689-122I6 (Retinal Pigment Epithelial Cells, donor3)
- 13663-147C9 (ARPE-19 EMT induced with TGF-beta and TNF-alpha)
- 13664-147D1 (ARPE-19 EMT induced with TGF-beta and TNF-alpha)
- 13665-147D2 (ARPE-19 EMT induced with TGF-beta and TNF-alpha, 06hr00min, biol_rep2)
- 13666-147D3 (ARPE-19 EMT induced with TGF-beta and TNF-alpha)
- 13667-147D4 (ARPE-19 EMT induced with TGF-beta and TNF-alpha)
- 13668-147D5 (ARPE-19 EMT induced with TGF-beta and TNF-alpha)
Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0001782 (pigmented layer of retina), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data
| P-value | FFCP | Short description |
|---|---|---|
| 2.79e-195 | FFCP PHASE2:Hg19::chr1:147150847..147150854,-#_9f7dbf71f3f059a0b649bc64883f1acf | p@chr1:147150847..147150854, - |
| 2.79e-195 | FFCP PHASE1:Hg19::chr1:147150847..147150854,-#_9f7dbf71f3f059a0b649bc64883f1acf | p@chr1:147150847..147150854, - |
| 3.27e-147 | FFCP PHASE2:Hg19::chr13:51913806..51913817,+#_49fdb21af4217d755cf58630b9af4de8 | p2@SERPINE3 |
| 3.27e-147 | FFCP PHASE1:Hg19::chr13:51913806..51913817,+#_49fdb21af4217d755cf58630b9af4de8 | p2@SERPINE3 |
| 5.41e-147 | FFCP PHASE1:Hg19::chr13:99135322..99135327,-#_cfb12de3bf771a66d1f6bac56c743447 | p@chr13:99135322..99135327, - |
| 5.41e-147 | FFCP PHASE2:Hg19::chr13:99135322..99135327,-#_cfb12de3bf771a66d1f6bac56c743447 | p@chr13:99135322..99135327, - |
| 8.98e-131 | FFCP PHASE2:Hg19::chr13:51913893..51913901,+#_18709429f3383a3d05e54b02e1c6a4b8 | p@chr13:51913893..51913901, + |
| 8.98e-131 | FFCP PHASE1:Hg19::chr13:51913893..51913901,+#_18709429f3383a3d05e54b02e1c6a4b8 | p@chr13:51913893..51913901, + |
| 3.48e-118 | FFCP PHASE1:Hg19::chr11:109990513..109990520,-#_c0f14d5c475472a051b78a26ec829852 | p@chr11:109990513..109990520, - |
| 3.48e-118 | FFCP PHASE2:Hg19::chr11:109990513..109990520,-#_c0f14d5c475472a051b78a26ec829852 | p@chr11:109990513..109990520, - |
| 1.16e-117 | FFCP PHASE1:Hg19::chr5:70308745..70308754,-#_631d53ddc1285555b696a2d0cfd7a00b | p@chr5:70308745..70308754, - |
| 1.16e-117 | FFCP PHASE2:Hg19::chr5:70308745..70308754,-#_631d53ddc1285555b696a2d0cfd7a00b | p@chr5:70308745..70308754, - |
| 7.95e-99 | FFCP PHASE1:Hg19::chr11:61522844..61522875,+#_d2747888d77ce46c3775f0bd1488c9c9 | p2@C11orf9 |
| 7.95e-99 | FFCP PHASE2:Hg19::chr11:61522844..61522875,+#_d2747888d77ce46c3775f0bd1488c9c9 | p2@C11orf9 |
| 2.17e-98 | FFCP PHASE2:Hg19::chr2:235591306..235591328,+#_2eba63f9e0336435c31f0a531b38ac42 | p@chr2:235591306..235591328, + |
| 2.17e-98 | FFCP PHASE1:Hg19::chr2:235591306..235591328,+#_2eba63f9e0336435c31f0a531b38ac42 | p@chr2:235591306..235591328, + |
| 6.24e-88 | FFCP PHASE1:Hg19::chr11:61522820..61522823,+#_d145b750f5c88c6cb57128ae810aa56f | p9@C11orf9 |
| 6.24e-88 | FFCP PHASE2:Hg19::chr11:61522820..61522823,+#_d145b750f5c88c6cb57128ae810aa56f | p9@C11orf9 |
| 9.74e-88 | FFCP PHASE2:Hg19::chr8:75898210..75898219,+#_df552b259893dd7ba36ce8fe6b1f3070 | p11@CRISPLD1 |
| 9.74e-88 | FFCP PHASE1:Hg19::chr8:75898210..75898219,+#_df552b259893dd7ba36ce8fe6b1f3070 | p11@CRISPLD1 |
| 1.52e-87 | FFCP PHASE2:Hg19::chr2:45166274..45166281,-#_dc4ba13c7b3a08b99b70a00e330b2456 | p5@ENST00000437916 |
| 1.52e-87 | FFCP PHASE1:Hg19::chr2:45166274..45166281,-#_dc4ba13c7b3a08b99b70a00e330b2456 | p5@ENST00000437916 |
| 2.28e-85 | FFCP PHASE1:Hg19::chr13:51913819..51913838,+#_82143b06b3bec80f0dbf904fbc4963d4 | p1@SERPINE3 |
| 2.28e-85 | FFCP PHASE2:Hg19::chr13:51913819..51913838,+#_82143b06b3bec80f0dbf904fbc4963d4 | p1@SERPINE3 |
| 1.01e-74 | FFCP PHASE1:Hg19::chr3:69928426..69928436,+#_c5768543d2edab0842d00f1a4fe663b2 | p@chr3:69928426..69928436, + |
| 1.01e-74 | FFCP PHASE2:Hg19::chr3:69928426..69928436,+#_c5768543d2edab0842d00f1a4fe663b2 | p@chr3:69928426..69928436, + |
| 1.29e-74 | FFCP PHASE2:Hg19::chr3:69928404..69928418,+#_90461782acdc02205385827845cd0df0 | p@chr3:69928404..69928418, + |
| 1.29e-74 | FFCP PHASE1:Hg19::chr3:69928404..69928418,+#_90461782acdc02205385827845cd0df0 | p@chr3:69928404..69928418, + |
| 2.14e-74 | FFCP PHASE1:Hg19::chr6:168250971..168250985,+#_1cb67501a155134dc7b0a32941ccdd62 | p@chr6:168250971..168250985, + |
| 2.14e-74 | FFCP PHASE2:Hg19::chr6:168250971..168250985,+#_1cb67501a155134dc7b0a32941ccdd62 | p@chr6:168250971..168250985, + |
| 2.14e-74 | FFCP PHASE1:Hg19::chr22:37633537..37633546,-#_1cb67501a155134dc7b0a32941ccdd62 | p@chr22:37633537..37633546, - |
| 2.14e-74 | FFCP PHASE2:Hg19::chr22:37633537..37633546,-#_1cb67501a155134dc7b0a32941ccdd62 | p@chr22:37633537..37633546, - |
| 3.54e-74 | FFCP PHASE1:Hg19::chr1:43533230..43533270,+#_2e92c2118ab60fa49ffbc03677e8bfcf | p@chr1:43533230..43533270, + |
| 3.54e-74 | FFCP PHASE2:Hg19::chr1:43533230..43533270,+#_2e92c2118ab60fa49ffbc03677e8bfcf | p@chr1:43533230..43533270, + |
| 1.54e-66 | FFCP PHASE1:Hg19::chr21:36041275..36041282,+#_d74bba9507044d4ca1674286d61af093 | p5@CLIC6 |
| 1.54e-66 | FFCP PHASE2:Hg19::chr21:36041275..36041282,+#_d74bba9507044d4ca1674286d61af093 | p5@CLIC6 |
| 2.39e-66 | FFCP PHASE2:Hg19::chr13:51913997..51914020,+#_dd9cad35948d1ec74da6d3acb6936b24 | p@chr13:51913997..51914020, + |
| 2.39e-66 | FFCP PHASE1:Hg19::chr13:51913997..51914020,+#_dd9cad35948d1ec74da6d3acb6936b24 | p@chr13:51913997..51914020, + |
| 6.53e-66 | FFCP PHASE1:Hg19::chr6:168251000..168251007,+#_9e31e9b81a6bd80ebdb5a4b0e6b87493 | p@chr6:168251000..168251007, + |
| 6.53e-66 | FFCP PHASE2:Hg19::chr6:168251000..168251007,+#_9e31e9b81a6bd80ebdb5a4b0e6b87493 | p@chr6:168251000..168251007, + |
| 2.98e-60 | FFCP PHASE2:Hg19::chr13:99135278..99135298,-#_738dbeca791825a8bfc7bf79a4686739 | p@chr13:99135278..99135298, - |
| 2.98e-60 | FFCP PHASE1:Hg19::chr13:99135278..99135298,-#_738dbeca791825a8bfc7bf79a4686739 | p@chr13:99135278..99135298, - |
| 5.01e-55 | FFCP PHASE2:Hg19::chr3:69928371..69928385,+#_9e7c34dc89ca8430db3304ff1ca131b9 | p@chr3:69928371..69928385, + |
| 5.01e-55 | FFCP PHASE1:Hg19::chr3:69928371..69928385,+#_9e7c34dc89ca8430db3304ff1ca131b9 | p@chr3:69928371..69928385, + |
| 7.24e-55 | FFCP PHASE2:Hg19::chr14:87636652..87636657,-#_6f802fe891eead563f326121edb2fa7e | p@chr14:87636652..87636657, - |
| 7.24e-55 | FFCP PHASE1:Hg19::chr14:87636652..87636657,-#_6f802fe891eead563f326121edb2fa7e | p@chr14:87636652..87636657, - |
| 1.68e-53 | FFCP PHASE2:Hg19::chr2:235591286..235591298,+#_0c3c46f0da1ce2ff6eabcb2f1cc7805b | p@chr2:235591286..235591298, + |
| 1.68e-53 | FFCP PHASE1:Hg19::chr2:235591286..235591298,+#_0c3c46f0da1ce2ff6eabcb2f1cc7805b | p@chr2:235591286..235591298, + |
| 6.39e-53 | FFCP PHASE1:Hg19::chr16:84228961..84228982,+#_b1303650edf6c39795b77dad071e0f19 | p@chr16:84228961..84228982, + |
| 6.39e-53 | FFCP PHASE1:Hg19::chr11:119217442..119217445,-#_b1303650edf6c39795b77dad071e0f19 | p5@MFRP, p6@C1QTNF5 |
| 6.39e-53 | FFCP PHASE2:Hg19::chr11:119217442..119217445,-#_b1303650edf6c39795b77dad071e0f19 | p5@MFRP, p6@C1QTNF5 |
| 6.39e-53 | FFCP PHASE2:Hg19::chr16:84228961..84228982,+#_b1303650edf6c39795b77dad071e0f19 | p@chr16:84228961..84228982, + |
| 9.6e-51 | FFCP PHASE1:Hg19::chr21:36041264..36041274,+#_1f0aaca7966283ff9e09a5f68242dacd | p3@CLIC6 |
| 9.6e-51 | FFCP PHASE2:Hg19::chr21:36041264..36041274,+#_1f0aaca7966283ff9e09a5f68242dacd | p3@CLIC6 |
| 1.89e-50 | FFCP PHASE2:Hg19::chr11:75201755..75201762,-#_8b03ac4dc01fb86dc1fd3ebc20c3e030 | p7@GDPD5 |
| 1.89e-50 | FFCP PHASE1:Hg19::chr11:75201755..75201762,-#_8b03ac4dc01fb86dc1fd3ebc20c3e030 | p7@GDPD5 |
| 7.24e-50 | FFCP PHASE2:Hg19::chr11:119217421..119217435,-#_b587ad0e0dde8f789c2c9a3f4d87a749 | p4@MFRP, p5@C1QTNF5 |
| 7.24e-50 | FFCP PHASE1:Hg19::chr11:119217421..119217435,-#_b587ad0e0dde8f789c2c9a3f4d87a749 | p4@MFRP, p5@C1QTNF5 |
| 6.25e-45 | FFCP PHASE2:Hg19::chr17:932596..932605,-#_f109dc0b882c84cf04cff084a082001f | p@chr17:932596..932605, - |
| 6.25e-45 | FFCP PHASE1:Hg19::chr17:932596..932605,-#_f109dc0b882c84cf04cff084a082001f | p@chr17:932596..932605, - |
| 1.22e-44 | FFCP PHASE1:Hg19::chr22:38480132..38480159,-#_5ca01b21b34cdc7c2f420e0443028f07 | p1@SLC16A8 |
| 1.22e-44 | FFCP PHASE2:Hg19::chr22:38480132..38480159,-#_5ca01b21b34cdc7c2f420e0443028f07 | p1@SLC16A8 |
| 1.22e-44 | FFCP PHASE2:Hg19::chr17:932340..932343,-#_5ca01b21b34cdc7c2f420e0443028f07 | p@chr17:932340..932343, - |
| 1.22e-44 | FFCP PHASE1:Hg19::chr17:932340..932343,-#_5ca01b21b34cdc7c2f420e0443028f07 | p@chr17:932340..932343, - |
| 1.22e-44 | FFCP PHASE1:Hg19::chr20:52790691..52790695,-#_5ca01b21b34cdc7c2f420e0443028f07 | p5@CYP24A1 |
| 1.22e-44 | FFCP PHASE2:Hg19::chr20:52790691..52790695,-#_5ca01b21b34cdc7c2f420e0443028f07 | p5@CYP24A1 |
| 2.38e-44 | FFCP PHASE2:Hg19::chr3:98672197..98672201,+#_ed7449815d56ec8fa44bdf9cf7996648 | p@chr3:98672197..98672201, + |
| 2.38e-44 | FFCP PHASE1:Hg19::chr3:98672197..98672201,+#_ed7449815d56ec8fa44bdf9cf7996648 | p@chr3:98672197..98672201, + |
| 2.97e-44 | FFCP PHASE2:Hg19::chr3:183733654..183733680,-#_1d18547829452a762418ed36d84ba14d | p@chr3:183733654..183733680, - |
| 2.97e-44 | FFCP PHASE2:Hg19::chr9:127025189..127025200,+#_1d18547829452a762418ed36d84ba14d | p1@ENST00000437461 |
| 2.97e-44 | FFCP PHASE1:Hg19::chr3:183733654..183733680,-#_1d18547829452a762418ed36d84ba14d | p@chr3:183733654..183733680, - |
| 2.97e-44 | FFCP PHASE1:Hg19::chr9:127025189..127025200,+#_1d18547829452a762418ed36d84ba14d | p1@ENST00000437461 |
| 4.49e-44 | FFCP PHASE2:Hg19::chr9:140088882..140088898,-#_ffe9835dae763e27f31e654bd1f8b8cc | p@chr9:140088882..140088898, - |
| 4.49e-44 | FFCP PHASE1:Hg19::chr9:140088882..140088898,-#_ffe9835dae763e27f31e654bd1f8b8cc | p@chr9:140088882..140088898, - |
| 1.24e-43 | FFCP PHASE2:Hg19::chr14:28081776..28081788,+#_b089e87f63181a0c22bbc6f58ec0eab2 | p1@LOC100505967 |
| 1.24e-43 | FFCP PHASE1:Hg19::chr14:28081776..28081788,+#_b089e87f63181a0c22bbc6f58ec0eab2 | p1@LOC100505967 |
| 2.95e-43 | FFCP PHASE2:Hg19::chr2:45169172..45169177,+#_5e0541e63fdb7654a75937ac627c82e4 | p11@SIX3 |
| 2.95e-43 | FFCP PHASE1:Hg19::chr2:45169172..45169177,+#_5e0541e63fdb7654a75937ac627c82e4 | p11@SIX3 |
| 4.55e-43 | FFCP PHASE1:Hg19::chr5:33984786..33984820,-#_7a1420bd9530a8e6a96828e1779924fa | p2@SLC45A2 |
| 4.55e-43 | FFCP PHASE2:Hg19::chr5:33984786..33984820,-#_7a1420bd9530a8e6a96828e1779924fa | p2@SLC45A2 |
| 3.86e-41 | FFCP PHASE1:Hg19::chr16:68301840..68301845,+#_284f3b5298b729d683092b2ea5810e05 | p@chr16:68301840..68301845, + |
| 3.86e-41 | FFCP PHASE2:Hg19::chr16:68301840..68301845,+#_284f3b5298b729d683092b2ea5810e05 | p@chr16:68301840..68301845, + |
| 9.96e-41 | FFCP PHASE2:Hg19::chr19:49140255..49140268,-#_eca03f0f464ccb648a1cd6c5efb05684 | p9@DBP |
| 9.96e-41 | FFCP PHASE1:Hg19::chr19:49140255..49140268,-#_eca03f0f464ccb648a1cd6c5efb05684 | p9@DBP |
| 1.31e-40 | FFCP PHASE2:Hg19::chr12:52579447..52579461,-#_089f7e0805906cf545a13e0f0630f04c | p6@KRT80 |
| 1.31e-40 | FFCP PHASE1:Hg19::chr12:52579447..52579461,-#_089f7e0805906cf545a13e0f0630f04c | p6@KRT80 |
| 1.49e-40 | FFCP PHASE2:Hg19::chr4:23886471..23886501,-#_f2b853036e2549ea59de95d7e057a308 | p5@PPARGC1A |
| 1.49e-40 | FFCP PHASE1:Hg19::chr4:23886471..23886501,-#_f2b853036e2549ea59de95d7e057a308 | p5@PPARGC1A |
| 1.71e-40 | FFCP PHASE1:Hg19::chr11:119217318..119217346,-#_6d2f4c0f2057ad1a001180d547b059d0 | p2@MFRP |
| 1.71e-40 | FFCP PHASE2:Hg19::chr11:119217318..119217346,-#_6d2f4c0f2057ad1a001180d547b059d0 | p2@MFRP |
| 1.96e-40 | FFCP PHASE1:Hg19::chr11:119217405..119217420,-#_f5f00f9aa9fe151b72fe8c0501faa45a | p3@C1QTNF5, p3@MFRP |
| 1.96e-40 | FFCP PHASE2:Hg19::chr11:119217405..119217420,-#_f5f00f9aa9fe151b72fe8c0501faa45a | p3@C1QTNF5, p3@MFRP |
| 2.93e-40 | FFCP PHASE2:Hg19::chr8:144905532..144905541,-#_b8f457d18ced0a96ce4e6a46322a9d2d | p6@PUF60 |
| 2.93e-40 | FFCP PHASE1:Hg19::chr8:144905532..144905541,-#_b8f457d18ced0a96ce4e6a46322a9d2d | p6@PUF60 |
| 3.83e-40 | FFCP PHASE2:Hg19::chr2:45162900..45162914,-#_8e1c6721ba822edd0b660ff3e96c617b | p1@ENST00000432125 |
| 3.83e-40 | FFCP PHASE1:Hg19::chr2:45162900..45162914,-#_8e1c6721ba822edd0b660ff3e96c617b | p1@ENST00000432125 |
| 6.54e-40 | FFCP PHASE2:Hg19::chr9:73483992..73484003,-#_a4296ab48808ba3eb57cb7dbccc837cf | p6@TRPM3 |
| 6.54e-40 | FFCP PHASE1:Hg19::chr9:73483992..73484003,-#_a4296ab48808ba3eb57cb7dbccc837cf | p6@TRPM3 |
| 1.11e-38 | FFCP PHASE2:Hg19::chr11:67776077..67776088,+#_eddb6d9567ecce82446093f606cf9c41 | p5@ALDH3B1 |
| 1.11e-38 | FFCP PHASE1:Hg19::chr11:67776077..67776088,+#_eddb6d9567ecce82446093f606cf9c41 | p5@ALDH3B1 |
Property "Property value" (as page type) with input value "UBPROP:0000001 "A monolayer of pigmented epithelium covering the neural retina; develops from the outer of the two layers of the optic cup. Kimmel et al, 1995.[TAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process., Property "Property value" (as page type) with input value "UBPROP:0000001 "The monolayer of pigmented epithelium covering the neural retina.[AAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.
