MCL coexpression mm9:200
From FANTOM5_SSTAR
Phase1 CAGE Peaks
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
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GO:0016860 | intramolecular oxidoreductase activity | 0.0364528008759897 |
GO:0008903 | hydroxypyruvate isomerase activity | 0.0364528008759897 |
GO:0016125 | sterol metabolic process | 0.0364528008759897 |
GO:0005159 | insulin-like growth factor receptor binding | 0.0364528008759897 |
GO:0047750 | cholestenol delta-isomerase activity | 0.0364528008759897 |
GO:0018445 | prothoracicotrophic hormone activity | 0.0364528008759897 |
GO:0033143 | regulation of steroid hormone receptor signaling pathway | 0.0364528008759897 |
GO:0009653 | anatomical structure morphogenesis | 0.0364528008759897 |
GO:0006707 | cholesterol catabolic process | 0.0364528008759897 |
GO:0016127 | sterol catabolic process | 0.0364528008759897 |
GO:0033344 | cholesterol efflux | 0.0364528008759897 |
GO:0008202 | steroid metabolic process | 0.0364528008759897 |
GO:0050650 | chondroitin sulfate proteoglycan biosynthetic process | 0.0364528008759897 |
GO:0050654 | chondroitin sulfate proteoglycan metabolic process | 0.0364528008759897 |
GO:0035239 | tube morphogenesis | 0.0364528008759897 |
GO:0016853 | isomerase activity | 0.0364528008759897 |
GO:0006706 | steroid catabolic process | 0.0364528008759897 |
GO:0065008 | regulation of biological quality | 0.0364528008759897 |
GO:0042627 | chylomicron | 0.0364528008759897 |
GO:0030104 | water homeostasis | 0.0364528008759897 |
GO:0017127 | cholesterol transporter activity | 0.0364528008759897 |
GO:0015198 | oligopeptide transporter activity | 0.0364528008759897 |
GO:0015248 | sterol transporter activity | 0.0364528008759897 |
GO:0015197 | peptide transporter activity | 0.0364528008759897 |
GO:0006857 | oligopeptide transport | 0.0364528008759897 |
GO:0018987 | osmoregulation | 0.0364528008759897 |
GO:0021940 | positive regulation of granule cell precursor proliferation | 0.0364528008759897 |
GO:0021936 | regulation of granule cell precursor proliferation | 0.0364528008759897 |
GO:0048009 | insulin-like growth factor receptor signaling pathway | 0.0364528008759897 |
GO:0035295 | tube development | 0.0364528008759897 |
GO:0021534 | cell proliferation in hindbrain | 0.0364528008759897 |
GO:0021924 | cell proliferation in the external granule layer | 0.0364528008759897 |
GO:0021930 | granule cell precursor proliferation | 0.0364528008759897 |
GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses | 0.0364528008759897 |
GO:0048878 | chemical homeostasis | 0.0364528008759897 |
GO:0031099 | regeneration | 0.0378566317807004 |
GO:0042246 | tissue regeneration | 0.0378566317807004 |
GO:0006950 | response to stress | 0.0389874105240323 |
GO:0030518 | steroid hormone receptor signaling pathway | 0.0413637874716506 |
GO:0008034 | lipoprotein binding | 0.0413637874716506 |
GO:0042311 | vasodilation | 0.0424139434841373 |
GO:0030301 | cholesterol transport | 0.0424139434841373 |
GO:0006066 | alcohol metabolic process | 0.0432302520435786 |
GO:0015918 | sterol transport | 0.0432302520435786 |
GO:0030166 | proteoglycan biosynthetic process | 0.0432302520435786 |
GO:0030246 | carbohydrate binding | 0.0432302520435786 |
GO:0016863 | intramolecular oxidoreductase activity, transposing C=C bonds | 0.0432302520435786 |
GO:0042632 | cholesterol homeostasis | 0.0432302520435786 |
GO:0055088 | lipid homeostasis | 0.0432302520435786 |
GO:0055092 | sterol homeostasis | 0.0432302520435786 |
GO:0030522 | intracellular receptor-mediated signaling pathway | 0.0448646382369213 |
GO:0005184 | neuropeptide hormone activity | 0.0455588305976605 |
GO:0006029 | proteoglycan metabolic process | 0.0455588305976605 |
GO:0005520 | insulin-like growth factor binding | 0.0493976601030036 |
Relative expression of the co-expression cluster over median <br>Analyst:
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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>
Ontology term | p-value | n |
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Ontology term | p-value | n |
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Ontology term | p-value | n |
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TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
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{{{tfbs_overrepresentation_jaspar}}} |