MCL coexpression mm9:2122

Phase1 CAGE Peaks

	Short description
Mm9::chr14:9090551..9090576,-	p7@Acox2
Mm9::chr14:9090582..9090612,-	p8@Acox2
Mm9::chr14:9091805..9091827,-	p5@Acox2
Mm9::chr6:86715860..86715915,-	p2@Anxa4

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0033791	3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity	0.00635511970634964
GO:0003997	acyl-CoA oxidase activity	0.0105907055519834
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	0.0105907055519834
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	0.0127078020996407
GO:0006635	fatty acid beta-oxidation	0.015879529810854
GO:0003995	acyl-CoA dehydrogenase activity	0.015879529810854
GO:0005544	calcium-dependent phospholipid binding	0.015879529810854
GO:0019395	fatty acid oxidation	0.015879529810854
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	0.0296239153511649
GO:0016324	apical plasma membrane	0.0310991397017297
GO:0050660	FAD binding	0.0340323921568733
GO:0001822	kidney development	0.034869854506458
GO:0045177	apical part of cell	0.034869854506458
GO:0001655	urogenital system development	0.034869854506458
GO:0042579	microbody	0.034869854506458
GO:0005777	peroxisome	0.034869854506458
GO:0050662	coenzyme binding	0.04322773381055

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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