MCL coexpression mm9:309

Phase1 CAGE Peaks

	Short description
Mm9::chr10:80858012..80858019,+	p@chr10:80858012..80858019 +
Mm9::chr13:76081122..76081144,-	p3@Rhobtb3
Mm9::chr16:4756879..4756881,+	p7@Hmox2
Mm9::chr16:78302789..78302793,+	p@chr16:78302789..78302793 +
Mm9::chr1:132748706..132748715,+	p@chr1:132748706..132748715 +
Mm9::chr2:121189397..121189406,+	p@chr2:121189397..121189406 +
Mm9::chr2:33226902..33226909,-	p3@Ralgps1
Mm9::chr3:122602255..122602301,+	p@chr3:122602255..122602301 +
Mm9::chr3:122602361..122602377,+	p@chr3:122602361..122602377 +
Mm9::chr4:119329240..119329253,-	p@chr4:119329240..119329253 -
Mm9::chr4:119329314..119329324,-	p@chr4:119329314..119329324 -
Mm9::chr6:128626637..128626642,+	p@chr6:128626637..128626642 +
Mm9::chr6:134555788..134555789,+	p@chr6:134555788..134555789 +
Mm9::chr6:3150760..3150769,+	p@chr6:3150760..3150769 +
Mm9::chr6:40719029..40719070,+	p@chr6:40719029..40719070 +
Mm9::chr6:71154894..71154926,+	p@chr6:71154894..71154926 +
Mm9::chr6:78323409..78323416,+	p@chr6:78323409..78323416 +
Mm9::chr7:147282990..147283018,+	p@chr7:147282990..147283018 +
Mm9::chr7:20257042..20257052,-	p@chr7:20257042..20257052 -
Mm9::chr7:20257138..20257177,-	p@chr7:20257138..20257177 -
Mm9::chr7:29626625..29626644,+	p@chr7:29626625..29626644 +
Mm9::chr9:46038350..46038357,+	p@chr9:46038350..46038357 +
Mm9::chr9:46038468..46038479,+	p@chr9:46038468..46038479 +
Mm9::chr9:46041182..46041206,-	p@chr9:46041182..46041206 -
Mm9::chr9:46051458..46051468,+	p@chr9:46051458..46051468 +
Mm9::chr9:98410082..98410102,+	p@chr9:98410082..98410102 +

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

---

GO ID	GO name	FDR corrected p-value
GO:0004392	heme oxygenase (decyclizing) activity	0.00985977183377446
GO:0006788	heme oxidation	0.00985977183377446
GO:0006787	porphyrin catabolic process	0.00985977183377446
GO:0033015	tetrapyrrole catabolic process	0.00985977183377446
GO:0042168	heme metabolic process	0.0337632798031105
GO:0006778	porphyrin metabolic process	0.0337632798031105
GO:0033013	tetrapyrrole metabolic process	0.0337632798031105
GO:0042440	pigment metabolic process	0.0466313321866766
GO:0051187	cofactor catabolic process	0.0466313321866766

Relative expression of the co-expression cluster over median <br>Analyst:

---

"{{{coexpression_dpi_cluster_scores_median}}}" is not a number.

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

---

Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

---

Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
{{{tfbs_overrepresentation_jaspar}}}