MCL coexpression mm9:2147

Phase1 CAGE Peaks

	Short description
Mm9::chr15:68141338..68141346,+	p2@Gm10045 p2@Gm10095 p2@Gm10163 p2@Gm10240 p2@Gm11703 p2@Gm13370 p2@Gm13653 p2@Gm15682 p2@Gm4478 p2@Gm5445 p2@Gm8101 p2@LOC100505283 p2@LOC634339 p2@Rpl21
Mm9::chr1:43245945..43245960,+	p1@uc007avm.2
Mm9::chr4:149689627..149689670,-	p1@ENSMUST00000167783
Mm9::chr5:5783629..5783638,-	p1@uc008wje.1

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0051085	chaperone cofactor-dependent protein folding	0.0332247092140442
GO:0006458	'de novo' protein folding	0.0332247092140442
GO:0051084	'de novo' posttranslational protein folding	0.0332247092140442

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

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Cell Type

Ontology term	p-value	n
animal cell	7.08e-39	115
eukaryotic cell	7.08e-39	115
somatic cell	4.37e-36	118
embryonic cell	4.66e-25	70
non-terminally differentiated cell	1.12e-24	49
somatic stem cell	2.86e-24	91
multi fate stem cell	2.86e-24	91
stem cell	5.75e-23	97
ectodermal cell	1.35e-21	44
neurectodermal cell	1.35e-21	44
neural cell	2.29e-21	43
electrically responsive cell	1.93e-19	39
electrically active cell	1.93e-19	39
neuron	2.66e-16	33
neuronal stem cell	2.66e-16	33
neuroblast	2.66e-16	33
electrically signaling cell	2.66e-16	33
motile cell	4.20e-13	54
CNS neuron (sensu Vertebrata)	7.12e-11	23
neuroblast (sensu Vertebrata)	7.12e-11	23
connective tissue cell	1.64e-09	46
mesenchymal cell	1.64e-09	46

Uber Anatomy

Ontology term	p-value	n
nervous system	1.06e-09	75
connective tissue	1.64e-09	46
central nervous system	7.59e-09	73
peripheral nervous system	1.54e-07	11

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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