MCL coexpression mm9:1477
From FANTOM5_SSTAR
Phase1 CAGE Peaks
| Short description | |
|---|---|
| Mm9::chr7:149844662..149844672,- | p8@Igf2 |
| Mm9::chrX:49625849..49625871,- | p@chrX:49625849..49625871 - |
| Mm9::chrX:49967074..49967087,- | p2@Gpc3 |
| Mm9::chrX:49967090..49967101,- | p3@Gpc3 |
| Mm9::chrX:49967113..49967156,- | p1@Gpc3 |
| Mm9::chrX:49967416..49967437,- | p4@Gpc3 |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0005159 | insulin-like growth factor receptor binding | 0.00723129172825533 |
| GO:0018445 | prothoracicotrophic hormone activity | 0.00723129172825533 |
| GO:0030513 | positive regulation of BMP signaling pathway | 0.00723129172825533 |
| GO:0008283 | cell proliferation | 0.00980652068650246 |
| GO:0009887 | organ morphogenesis | 0.00980652068650246 |
| GO:0030510 | regulation of BMP signaling pathway | 0.017166789799002 |
| GO:0001658 | ureteric bud branching | 0.017166789799002 |
| GO:0005184 | neuropeptide hormone activity | 0.017166789799002 |
| GO:0045926 | negative regulation of growth | 0.0200748149452051 |
| GO:0030509 | BMP signaling pathway | 0.0202856665377052 |
| GO:0001657 | ureteric bud development | 0.0202856665377052 |
| GO:0009653 | anatomical structure morphogenesis | 0.0202856665377052 |
| GO:0001656 | metanephros development | 0.0247492752265413 |
| GO:0048513 | organ development | 0.0247492752265413 |
| GO:0048754 | branching morphogenesis of a tube | 0.0271467911307937 |
| GO:0001763 | morphogenesis of a branching structure | 0.0271467911307937 |
| GO:0009967 | positive regulation of signal transduction | 0.0271467911307937 |
| GO:0001822 | kidney development | 0.0271467911307937 |
| GO:0048731 | system development | 0.0271467911307937 |
| GO:0001655 | urogenital system development | 0.0271467911307937 |
| GO:0007178 | transmembrane receptor protein serine/threonine kinase signaling pathway | 0.0271467911307937 |
| GO:0048856 | anatomical structure development | 0.0319733690770696 |
| GO:0005615 | extracellular space | 0.0319733690770696 |
| GO:0008285 | negative regulation of cell proliferation | 0.0319733690770696 |
| GO:0048503 | GPI anchor binding | 0.0319733690770696 |
| GO:0005179 | hormone activity | 0.0319733690770696 |
| GO:0044421 | extracellular region part | 0.0319733690770696 |
| GO:0007275 | multicellular organismal development | 0.0321147276600331 |
| GO:0035239 | tube morphogenesis | 0.0346178339930072 |
| GO:0040008 | regulation of growth | 0.0346178339930072 |
| GO:0008083 | growth factor activity | 0.0346178339930072 |
| GO:0035091 | phosphoinositide binding | 0.0368969072946606 |
| GO:0005543 | phospholipid binding | 0.0425178054670808 |
| GO:0035295 | tube development | 0.0425178054670808 |
| GO:0032502 | developmental process | 0.0444869144100882 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>
| Ontology term | p-value | n |
|---|---|---|
| multi-cellular organism | 8.81e-11 | 333 |
| embryo | 3.24e-07 | 320 |
| trunk region element | 4.11e-07 | 79 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
| MA0003.1 | 1.03722 |
| MA0004.1 | 0.536396 |
| MA0006.1 | 0.359699 |
| MA0007.1 | 1.29371 |
| MA0009.1 | 0.987341 |
| MA0014.1 | 9.25427 |
| MA0017.1 | 0.387481 |
| MA0019.1 | 0.800946 |
| MA0024.1 | 0.942716 |
| MA0025.1 | 1.22395 |
| MA0027.1 | 2.64231 |
| MA0028.1 | 0.370592 |
| MA0029.1 | 0.920529 |
| MA0030.1 | 0.927235 |
| MA0031.1 | 0.890871 |
| MA0038.1 | 0.686534 |
| MA0040.1 | 1.00009 |
| MA0041.1 | 0.457338 |
| MA0042.1 | 0.443591 |
| MA0043.1 | 1.08567 |
| MA0046.1 | 1.02391 |
| MA0048.1 | 0.486223 |
| MA0050.1 | 0.57678 |
| MA0051.1 | 0.695779 |
| MA0052.1 | 1.00829 |
| MA0055.1 | 0.0585191 |
| MA0056.1 | 0 |
| MA0057.1 | 0.895081 |
| MA0058.1 | 0.436487 |
| MA0059.1 | 0.449345 |
| MA0060.1 | 0.757042 |
| MA0061.1 | 0.307097 |
| MA0063.1 | 0 |
| MA0066.1 | 0.675169 |
| MA0067.1 | 1.33603 |
| MA0068.1 | 0.153907 |
| MA0069.1 | 1.00864 |
| MA0070.1 | 0.998765 |
| MA0071.1 | 0.575909 |
| MA0072.1 | 0.990133 |
| MA0073.1 | 0.401473 |
| MA0074.1 | 0.638014 |
| MA0076.1 | 0.407465 |
| MA0077.1 | 0.968053 |
| MA0078.1 | 0.729877 |
| MA0081.1 | 0.473489 |
| MA0083.1 | 1.08487 |
| MA0084.1 | 1.66561 |
| MA0087.1 | 1.04109 |
| MA0088.1 | 1.74419 |
| MA0089.1 | 0 |
| MA0090.1 | 0.500693 |
| MA0091.1 | 0.55008 |
| MA0092.1 | 1.25163 |
| MA0093.1 | 0.379257 |
| MA0095.1 | 0 |
| MA0098.1 | 0 |
| MA0100.1 | 0.626021 |
| MA0101.1 | 0.458688 |
| MA0103.1 | 0.398766 |
| MA0105.1 | 0.199622 |
| MA0106.1 | 0.737893 |
| MA0107.1 | 0.392331 |
| MA0108.2 | 0.824407 |
| MA0109.1 | 0 |
| MA0111.1 | 1.2824 |
| MA0113.1 | 0.708789 |
| MA0114.1 | 0.304661 |
| MA0115.1 | 1.08851 |
| MA0116.1 | 0.359483 |
| MA0117.1 | 1.05576 |
| MA0119.1 | 0.459301 |
| MA0122.1 | 1.07591 |
| MA0124.1 | 1.28237 |
| MA0125.1 | 1.20757 |
| MA0130.1 | 0 |
| MA0131.1 | 0.796279 |
| MA0132.1 | 0 |
| MA0133.1 | 0 |
| MA0135.1 | 1.1226 |
| MA0136.1 | 0.658622 |
| MA0139.1 | 0.243463 |
| MA0140.1 | 0.625902 |
| MA0141.1 | 0.419361 |
| MA0142.1 | 0.876028 |
| MA0143.1 | 0.725672 |
| MA0144.1 | 0.307873 |
| MA0145.1 | 0.119202 |
| MA0146.1 | 0.353523 |
| MA0147.1 | 0.320675 |
| MA0148.1 | 0.553294 |
| MA0149.1 | 0.464445 |
| MA0062.2 | 0.204999 |
| MA0035.2 | 0.630778 |
| MA0039.2 | 3.59125 |
| MA0138.2 | 0.788113 |
| MA0002.2 | 0.689262 |
| MA0137.2 | 0.416331 |
| MA0104.2 | 0.261255 |
| MA0047.2 | 0.685741 |
| MA0112.2 | 0.119197 |
| MA0065.2 | 0.380324 |
| MA0150.1 | 1.29346 |
| MA0151.1 | 0 |
| MA0152.1 | 0.685852 |
| MA0153.1 | 1.13945 |
| MA0154.1 | 0.159217 |
| MA0155.1 | 0.822245 |
| MA0156.1 | 0.406559 |
| MA0157.1 | 0.843181 |
| MA0158.1 | 0 |
| MA0159.1 | 0.331229 |
| MA0160.1 | 0.556423 |
| MA0161.1 | 0 |
| MA0162.1 | 0.70356 |
| MA0163.1 | 0.163321 |
| MA0164.1 | 0.658997 |
| MA0080.2 | 0.393257 |
| MA0018.2 | 0.669032 |
| MA0099.2 | 0.781628 |
| MA0079.2 | 1.33539 |
| MA0102.2 | 1.7182 |
| MA0258.1 | 0.290587 |
| MA0259.1 | 0.833237 |
| MA0442.1 | 0 |
