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CL:0000623

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Name:natural killer cell
Namespace:cell
Definition:"A lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation via germline encoded activation receptors and also regulate immune responses via cytokine release and direct contact with other cells." [GOC:add, ISBN:0781735149, PMID:15771571]
Xrefs:
links:

BTO:0000914
BTO:0004716
FMA:63147

FMA:83601
Synonyms: "large granular lymphocyte" BROAD []
"NK cell" EXACT []
"null cell" BROAD []


Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data


Parents

is_a:CL:0000542(lymphocyte)
develops_from:CL:0000825(pro-NK cell)



Children


disjoint from:CL:0000084 (T cell)
derives from:FF:0000119 (human natural killer cell sample)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)


FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.


Human (Homo sapiens)

Mouse (Mus musculus)


Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000623 (natural killer cell), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data