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CL:0000826

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Name:pro-B cell
Namespace:FANTOM
Definition:"A progenitor cell of the B cell lineage, with some lineage specific activity such as early stages of recombination of B cell receptor genes, but not yet fully committed to the B cell lineage until the expression of PAX5 occurs." [GOC:add, ISBN:0781735149, PMID:12633665]
Xrefs:
links:
BTO:0003104
Synonyms: "pre-B cell (Philadelphia nomenclature)" RELATED [PMID:11244048]
"pre-pro B cell" BROAD [PMID:17582343]
"pro-B lymphocyte" EXACT []
"pro-B-cell" EXACT []
"pro-B-lymphocyte" EXACT []
"progenitor B cell" EXACT []


Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data


Parents

is_a:CL:0000838(lymphoid lineage restricted progenitor cell)
develops_from:CL:0000051(common lymphoid progenitor)



Children


disjoint from:CL:0000817 (precursor B cell)
develops from:CL:0000236 (B cell),CL:0000945 (lymphocyte of B lineage),CL:0000955 (pre-B-II cell)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)


FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.




Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000826 (pro-B cell), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data