CL:0000990

Name:	conventional dendritic cell
Namespace:	FANTOM
Definition:	"Conventional dendritic cell is a dendritic cell that is CD11c-high." [GO_REF:0000031, GOC:amm, PMID:17850486]
Xrefs:	Expandlinks: FMA:84191
Synonyms:	"cDC" EXACT [] "DC1" EXACT [] "dendritic reticular cell" EXACT [] "interdigitating cell" BROAD [] "type 1 DC" EXACT [] "veiled cell" BROAD []
Comments:	Originally described in the dendritic cell ontology (DC_CL: 0000003)(PMID: 19243617) These cells are also CD20-negative, MHCII-positive.

Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data

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Parents

is_a:	CL:0000451(dendritic cell)

Children

is a:	CL:0000453 (Langerhans cell),CL:0000840 (immature conventional dendritic cell)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.

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Human (Homo sapiens)

• 10457-106G7 (squamous cell lung carcinoma cell line:LC-1F)
• 10501-107C6 (squamous cell lung carcinoma cell line:RERF-LC-AI)
• 11227-116C3 (Dendritic Cells - monocyte immature derived, donor1)
• 11228-116C4 (Dendritic Cells - plasmacytoid, donor1)
• 11308-117C3 (Dendritic Cells - monocyte immature derived, donor2)
• 11384-118B7 (Dendritic Cells - monocyte immature derived, donor3)
• 11901-125F2 (migratory langerhans cells, donor1)
• 11902-125F3 (migratory langerhans cells, donor2)
• 11903-125F4 (migratory langerhans cells, donor3)
• 11904-125F5 (immature langerhans cells, donor1)

... further results Mouse (Mus musculus)

• 10457-106G7 (squamous cell lung carcinoma cell line:LC-1F)
• 10501-107C6 (squamous cell lung carcinoma cell line:RERF-LC-AI)
• 11227-116C3 (Dendritic Cells - monocyte immature derived, donor1)
• 11228-116C4 (Dendritic Cells - plasmacytoid, donor1)
• 11308-117C3 (Dendritic Cells - monocyte immature derived, donor2)
• 11384-118B7 (Dendritic Cells - monocyte immature derived, donor3)
• 11901-125F2 (migratory langerhans cells, donor1)
• 11902-125F3 (migratory langerhans cells, donor2)
• 11903-125F4 (migratory langerhans cells, donor3)
• 11904-125F5 (immature langerhans cells, donor1)

... further results

Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000990 (conventional dendritic cell), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

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P-value	FFCP	Short description

P-value	FFCP	Short description
9.96e-174	FFCP PHASE2:Hg19::chr15:101535004..101535045,+	p@chr15:101535004..101535045, +
9.96e-174	FFCP PHASE1:Hg19::chr15:101535004..101535045,+	p@chr15:101535004..101535045, +
3.95e-152	FFCP PHASE2:Hg19::chr15:101534994..101535003,+	p@chr15:101534994..101535003, +
3.95e-152	FFCP PHASE2:Hg19::chr16:57398251..57398254,+	p@chr16:57398251..57398254, +
3.95e-152	FFCP PHASE1:Hg19::chr16:57398251..57398254,+	p@chr16:57398251..57398254, +
3.95e-152	FFCP PHASE1:Hg19::chr15:101534994..101535003,+	p@chr15:101534994..101535003, +
1.9e-139	FFCP PHASE1:Hg19::chr13:75884283..75884317,-	p@chr13:75884283..75884317, -
1.9e-139	FFCP PHASE2:Hg19::chr13:75884283..75884317,-	p@chr13:75884283..75884317, -
1.82e-133	FFCP PHASE2:Hg19::chr15:101529373..101529387,+	p@chr15:101529373..101529387, +
1.82e-133	FFCP PHASE1:Hg19::chr16:10960104..10960115,+	p4@AB463580
1.82e-133	FFCP PHASE1:Hg19::chr15:101529373..101529387,+	p@chr15:101529373..101529387, +
1.82e-133	FFCP PHASE2:Hg19::chr16:10960104..10960115,+	p4@AB463580
1.42e-130	FFCP PHASE1:Hg19::chr2:61080954..61080964,+	p@chr2:61080954..61080964, +
1.42e-130	FFCP PHASE2:Hg19::chr3:119198717..119198735,+	p@chr3:119198717..119198735, +
1.42e-130	FFCP PHASE2:Hg19::chr2:61080954..61080964,+	p@chr2:61080954..61080964, +
1.42e-130	FFCP PHASE1:Hg19::chr3:119198717..119198735,+	p@chr3:119198717..119198735, +
1.42e-130	FFCP PHASE2:Hg19::chr18:59991691..59991708,+	p@chr18:59991691..59991708, +
1.42e-130	FFCP PHASE1:Hg19::chr18:59991691..59991708,+	p@chr18:59991691..59991708, +
3.16e-127	FFCP PHASE1:Hg19::chr16:10960091..10960099,+	p3@AB463580
3.16e-127	FFCP PHASE2:Hg19::chr16:10960091..10960099,+	p3@AB463580
8.55e-119	FFCP PHASE1:Hg19::chr16:57398441..57398460,+	p@chr16:57398441..57398460, +
8.55e-119	FFCP PHASE1:Hg19::chr12:112513512..112513567,-	p@chr12:112513512..112513567, -
8.55e-119	FFCP PHASE2:Hg19::chr12:112513512..112513567,-	p@chr12:112513512..112513567, -
8.55e-119	FFCP PHASE2:Hg19::chr16:57398441..57398460,+	p@chr16:57398441..57398460, +
1.19e-116	FFCP PHASE1:Hg19::chr13:75884320..75884362,-	p@chr13:75884320..75884362, -
1.19e-116	FFCP PHASE2:Hg19::chr13:75884320..75884362,-	p@chr13:75884320..75884362, -
3.66e-112	FFCP PHASE2:Hg19::chr16:57398263..57398266,+	p@chr16:57398263..57398266, +
3.66e-112	FFCP PHASE1:Hg19::chr16:57398263..57398266,+	p@chr16:57398263..57398266, +
4.43e-112	FFCP PHASE1:Hg19::chr16:57398271..57398274,+	p@chr16:57398271..57398274, +
4.43e-112	FFCP PHASE2:Hg19::chr16:57398271..57398274,+	p@chr16:57398271..57398274, +
4.6e-109	FFCP PHASE1:Hg19::chr1:201376546..201376550,+	p@chr1:201376546..201376550, +
4.6e-109	FFCP PHASE2:Hg19::chr13:75884392..75884395,-	p@chr13:75884392..75884395, -
4.6e-109	FFCP PHASE1:Hg19::chr3:52813932..52813943,+	p11@ITIH1
4.6e-109	FFCP PHASE2:Hg19::chr16:10959868..10959879,+	p2@AB463580
4.6e-109	FFCP PHASE2:Hg19::chr16:10885979..10885991,+	p@chr16:10885979..10885991, +
4.6e-109	FFCP PHASE1:Hg19::chr6:32726761..32726781,-	p@chr6:32726761..32726781, -
4.6e-109	FFCP PHASE1:Hg19::chr19:45487650..45487661,+	p@chr19:45487650..45487661, +
4.6e-109	FFCP PHASE2:Hg19::chr6:32726761..32726781,-	p@chr6:32726761..32726781, -
4.6e-109	FFCP PHASE1:Hg19::chr16:10959804..10959811,+	p5@AB463580
4.6e-109	FFCP PHASE2:Hg19::chr16:10959880..10959887,+	p6@AB463580
4.6e-109	FFCP PHASE1:Hg19::chr3:119188705..119188718,+	p@chr3:119188705..119188718, +
4.6e-109	FFCP PHASE1:Hg19::chr16:10959868..10959879,+	p2@AB463580
4.6e-109	FFCP PHASE1:Hg19::chr16:10885979..10885991,+	p@chr16:10885979..10885991, +
4.6e-109	FFCP PHASE2:Hg19::chr1:201376546..201376550,+	p@chr1:201376546..201376550, +
4.6e-109	FFCP PHASE1:Hg19::chr6:32729529..32729536,-	p3@M95729
4.6e-109	FFCP PHASE2:Hg19::chr3:52813932..52813943,+	p11@ITIH1
4.6e-109	FFCP PHASE2:Hg19::chr6:32729529..32729536,-	p3@M95729
4.6e-109	FFCP PHASE1:Hg19::chr16:10959880..10959887,+	p6@AB463580
4.6e-109	FFCP PHASE2:Hg19::chr19:45487650..45487661,+	p@chr19:45487650..45487661, +
4.6e-109	FFCP PHASE1:Hg19::chr8:120974832..120974840,+	p@chr8:120974832..120974840, +
4.6e-109	FFCP PHASE2:Hg19::chr8:120974832..120974840,+	p@chr8:120974832..120974840, +
4.6e-109	FFCP PHASE2:Hg19::chr16:10959804..10959811,+	p5@AB463580
4.6e-109	FFCP PHASE2:Hg19::chr3:119188705..119188718,+	p@chr3:119188705..119188718, +
4.6e-109	FFCP PHASE1:Hg19::chr13:75884392..75884395,-	p@chr13:75884392..75884395, -
4.63e-108	FFCP PHASE2:Hg19::chr16:57397882..57397931,-	p1@CU693343
4.63e-108	FFCP PHASE1:Hg19::chr16:57397882..57397931,-	p1@CU693343
5.32e-108	FFCP PHASE2:Hg19::chr16:57397593..57397602,+	p@chr16:57397593..57397602, +
5.32e-108	FFCP PHASE1:Hg19::chr16:57397593..57397602,+	p@chr16:57397593..57397602, +
8.06e-108	FFCP PHASE2:Hg19::chr16:57399022..57399038,+	p@chr16:57399022..57399038, +
8.06e-108	FFCP PHASE1:Hg19::chr16:57399022..57399038,+	p@chr16:57399022..57399038, +
2.5e-107	FFCP PHASE2:Hg19::chr16:57394436..57394449,+	p@chr16:57394436..57394449, +
2.5e-107	FFCP PHASE1:Hg19::chr16:57394436..57394449,+	p@chr16:57394436..57394449, +
3.43e-107	FFCP PHASE1:Hg19::chr16:57399043..57399070,+	p@chr16:57399043..57399070, +
3.43e-107	FFCP PHASE2:Hg19::chr16:57399043..57399070,+	p@chr16:57399043..57399070, +
4.01e-107	FFCP PHASE2:Hg19::chr16:57397927..57397934,+	p@chr16:57397927..57397934, +
4.01e-107	FFCP PHASE1:Hg19::chr16:57397927..57397934,+	p@chr16:57397927..57397934, +
1.07e-100	FFCP PHASE2:Hg19::chr16:57397735..57397758,-	p3@CU693343
1.07e-100	FFCP PHASE1:Hg19::chr16:57397735..57397758,-	p3@CU693343
1.07e-100	FFCP PHASE2:Hg19::chr16:57398987..57399006,+	p@chr16:57398987..57399006, +
1.07e-100	FFCP PHASE1:Hg19::chr16:57398987..57399006,+	p@chr16:57398987..57399006, +
2.05e-99	FFCP PHASE1:Hg19::chr6:341221..341236,-	p@chr6:341221..341236, -
2.05e-99	FFCP PHASE2:Hg19::chr6:341221..341236,-	p@chr6:341221..341236, -
5.3e-94	FFCP PHASE2:Hg19::chr16:57397561..57397572,+	p@chr16:57397561..57397572, +
5.3e-94	FFCP PHASE1:Hg19::chr16:57397561..57397572,+	p@chr16:57397561..57397572, +
3.38e-91	FFCP PHASE1:Hg19::chr2:173867941..173867955,+	p@chr2:173867941..173867955, +
3.38e-91	FFCP PHASE2:Hg19::chr1:159272441..159272452,+	p5@FCER1A
3.38e-91	FFCP PHASE2:Hg19::chr2:173867941..173867955,+	p@chr2:173867941..173867955, +
3.38e-91	FFCP PHASE1:Hg19::chr1:159272441..159272452,+	p5@FCER1A
3.38e-91	FFCP PHASE1:Hg19::chr13:75884255..75884262,-	p@chr13:75884255..75884262, -
3.38e-91	FFCP PHASE2:Hg19::chr13:75884255..75884262,-	p@chr13:75884255..75884262, -
4.08e-91	FFCP PHASE2:Hg19::chr1:159272420..159272431,+	p3@FCER1A
4.08e-91	FFCP PHASE1:Hg19::chr1:159272420..159272431,+	p3@FCER1A
1.95e-88	FFCP PHASE1:Hg19::chr16:57394384..57394402,+	p@chr16:57394384..57394402, +
1.95e-88	FFCP PHASE2:Hg19::chr16:57394384..57394402,+	p@chr16:57394384..57394402, +
2.18e-88	FFCP PHASE1:Hg19::chr16:57397581..57397590,+	p@chr16:57397581..57397590, +
2.18e-88	FFCP PHASE2:Hg19::chr16:57397581..57397590,+	p@chr16:57397581..57397590, +
1.15e-87	FFCP PHASE1:Hg19::chr1:157108764..157108776,-	p7@ETV3
1.15e-87	FFCP PHASE2:Hg19::chr1:157108764..157108776,-	p7@ETV3
1.37e-87	FFCP PHASE1:Hg19::chr12:95264953..95264971,-	p@chr12:95264953..95264971, -
1.37e-87	FFCP PHASE2:Hg19::chr12:95264953..95264971,-	p@chr12:95264953..95264971, -
1.37e-87	FFCP PHASE1:Hg19::chr14:65641128..65641129,-	p@chr14:65641128..65641129, -
1.37e-87	FFCP PHASE1:Hg19::chr12:112590221..112590232,+	p@chr12:112590221..112590232, +
1.37e-87	FFCP PHASE1:Hg19::chr16:10870586..10870591,-	p@chr16:10870586..10870591, -
1.37e-87	FFCP PHASE2:Hg19::chr16:57399642..57399651,+	p@chr16:57399642..57399651, +
1.37e-87	FFCP PHASE2:Hg19::chr18:22537624..22537627,-	p@chr18:22537624..22537627, -
1.37e-87	FFCP PHASE1:Hg19::chr4:16267477..16267486,-	p@chr4:16267477..16267486, -
1.37e-87	FFCP PHASE1:Hg19::chr3:52813951..52813958,+	p13@ITIH1
1.37e-87	FFCP PHASE1:Hg19::chr2:61081057..61081064,+	p@chr2:61081057..61081064, +
1.37e-87	FFCP PHASE1:Hg19::chr6:32729494..32729506,-	p1@M95729
1.37e-87	FFCP PHASE2:Hg19::chr4:14845952..14845956,-	p@chr4:14845952..14845956, -

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