CL:0002224
From FANTOM5_SSTAR
| Name: | lens epithelial cell | ||
|---|---|---|---|
| Namespace: | FANTOM | ||
| Definition: | "A cell of the cuboidal epithelium that covers the lens. The cells of the lens epithelium regulate most of the homeostatic functions of the lens. As ions, nutrients, and liquid enter the lens from the aqueous humor, Na+/K+ ATPase pumps in the lens epithelial cells pump ions out of the lens to maintain appropriate lens osmolarity and volume, with equatorially positioned lens epithelium cells contributing most to this current. The activity of the Na+/K+ ATPases keeps water and current flowing through the lens from the poles and exiting through the equatorial regions. The cells of the lens epithelium also serve as the progenitors for new lens fibers. It constantly lays down fibers in the embryo, fetus, infant, and adult, and continues to lay down fibers for lifelong growth." [GOC:tfm, http://en.wikipedia.org/wiki/Lens_%28anatomy%29#Lens_epithelium, ISBN:0721662544] | ||
| Xrefs: |
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| Created by: | tmeehan | ||
| Creation date: | 2010-09-07T10:45:47Z |
Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data
Parents
| is_a: | CL:0000075(columnar/cuboidal epithelial cell),CL:0002222(vertebrate lens cell) |
|---|---|
| part_of: | UBERON:0001803(epithelium of lens) |
Children
| is a: | FF:10647-109A8 (lens epithelial cell line:SRA 01/04) |
|---|---|
| derives from: | FF:0000085 (human lens epithelial cell sample),FF:0101874 (lens epithelial cell line sample) |
Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.
Human (Homo sapiens)
- 10647-109A8 (lens epithelial cell line:SRA 01/04)
- 11529-119I8 (Lens Epithelial Cells, donor1)
- 11609-120I7 (Lens Epithelial Cells, donor2)
- 11690-122I7 (Lens Epithelial Cells, donor3)
Mouse (Mus musculus)
- 10647-109A8 (lens epithelial cell line:SRA 01/04)
- 11529-119I8 (Lens Epithelial Cells, donor1)
- 11609-120I7 (Lens Epithelial Cells, donor2)
- 11690-122I7 (Lens Epithelial Cells, donor3)
Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0002224 (lens epithelial cell), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data
| P-value | FFCP | Short description |
|---|---|---|
| 1.41e-88 | FFCP PHASE2:Hg19::chr22:25595823..25595826,+#_c79805b31d40abedb1e461788f43f1af | p1@CRYBB3 |
| 1.41e-88 | FFCP PHASE1:Hg19::chr22:25595823..25595826,+#_c79805b31d40abedb1e461788f43f1af | p1@CRYBB3 |
| 3.32e-74 | FFCP PHASE1:Hg19::chr22:25615600..25615611,+#_8c620954a636fdc13e9ed5402f803d2c | p1@CRYBB2 |
| 3.32e-74 | FFCP PHASE2:Hg19::chr22:25615600..25615611,+#_8c620954a636fdc13e9ed5402f803d2c | p1@CRYBB2 |
| 5.48e-74 | FFCP PHASE1:Hg19::chr19:51891222..51891233,-#_7e71c8e0285a7f40010c36106ff61be4 | p1@LIM2 |
| 5.48e-74 | FFCP PHASE2:Hg19::chr19:51891222..51891233,-#_7e71c8e0285a7f40010c36106ff61be4 | p1@LIM2 |
| 3.8e-56 | FFCP PHASE2:Hg19::chr22:27017921..27017928,+#_0cadfdf6e5c295a521ac826690567aea | p1@CRYBA4 |
| 3.8e-56 | FFCP PHASE1:Hg19::chr22:27017921..27017928,+#_0cadfdf6e5c295a521ac826690567aea | p1@CRYBA4 |
| 3.1e-50 | FFCP PHASE1:Hg19::chr20:61204240..61204241,+#_4b7384f1d5ae52f3a79ac3cdbf959ba8 | p@chr20:61204240..61204241, + |
| 3.1e-50 | FFCP PHASE1:Hg19::chr13:104778247..104778293,+#_4b7384f1d5ae52f3a79ac3cdbf959ba8 | p@chr13:104778247..104778293, + |
| 3.1e-50 | FFCP PHASE2:Hg19::chr13:104778247..104778293,+#_4b7384f1d5ae52f3a79ac3cdbf959ba8 | p@chr13:104778247..104778293, + |
| 3.1e-50 | FFCP PHASE2:Hg19::chr20:61204240..61204241,+#_4b7384f1d5ae52f3a79ac3cdbf959ba8 | p@chr20:61204240..61204241, + |
| 5.14e-50 | FFCP PHASE2:Hg19::chr14:37642016..37642022,-#_cb12312e65231cf7e01ee02bd2a4c3f6 | p7@SLC25A21 |
| 5.14e-50 | FFCP PHASE2:Hg19::chr21:44592820..44592840,-#_cb12312e65231cf7e01ee02bd2a4c3f6 | p2@CU686889 |
| 5.14e-50 | FFCP PHASE1:Hg19::chr21:44592820..44592840,-#_cb12312e65231cf7e01ee02bd2a4c3f6 | p2@CU686889 |
| 5.14e-50 | FFCP PHASE1:Hg19::chr14:37642016..37642022,-#_cb12312e65231cf7e01ee02bd2a4c3f6 | p7@SLC25A21 |
| 6.6e-50 | FFCP PHASE1:Hg19::chr21:44589339..44589372,-#_d0f684a0fd03fff3259002f81f5de4f2 | p@chr21:44589339..44589372, - |
| 6.6e-50 | FFCP PHASE1:Hg19::chr12:132475501..132475504,+#_d0f684a0fd03fff3259002f81f5de4f2 | p@chr12:132475501..132475504, + |
| 6.6e-50 | FFCP PHASE2:Hg19::chr21:44592842..44592867,-#_d0f684a0fd03fff3259002f81f5de4f2 | p1@CU686889 |
| 6.6e-50 | FFCP PHASE2:Hg19::chr12:132475501..132475504,+#_d0f684a0fd03fff3259002f81f5de4f2 | p@chr12:132475501..132475504, + |
| 6.6e-50 | FFCP PHASE2:Hg19::chr21:44589339..44589372,-#_d0f684a0fd03fff3259002f81f5de4f2 | p@chr21:44589339..44589372, - |
| 6.6e-50 | FFCP PHASE1:Hg19::chr21:44592842..44592867,-#_d0f684a0fd03fff3259002f81f5de4f2 | p1@CU686889 |
| 6.27e-44 | FFCP PHASE1:Hg19::chr11:31827535..31827565,-#_ba01e6c97373209799fae105d0a0f17c | p11@PAX6 |
| 6.27e-44 | FFCP PHASE2:Hg19::chr11:31827535..31827565,-#_ba01e6c97373209799fae105d0a0f17c | p11@PAX6 |
| 1.92e-41 | FFCP PHASE2:Hg19::chr3:186262166..186262170,-#_d7fd12bdea244afac4a4c7f6fd1ee31f | p1@CRYGS |
| 1.92e-41 | FFCP PHASE1:Hg19::chr3:186262166..186262170,-#_d7fd12bdea244afac4a4c7f6fd1ee31f | p1@CRYGS |
| 4.94e-40 | FFCP PHASE2:Hg19::chr5:112173525..112173532,+#_b3bbb558b64545ae696ce58ebb9b3061 | p@chr5:112173525..112173532, + |
| 4.94e-40 | FFCP PHASE1:Hg19::chr5:112173525..112173532,+#_b3bbb558b64545ae696ce58ebb9b3061 | p@chr5:112173525..112173532, + |
| 1.62e-37 | FFCP PHASE2:Hg19::chr1:29586692..29586705,+#_992578449e75fdc6c9b7942e6b456edb | p7@PTPRU |
| 1.62e-37 | FFCP PHASE1:Hg19::chr1:29586692..29586705,+#_992578449e75fdc6c9b7942e6b456edb | p7@PTPRU |
| 2.1e-35 | FFCP PHASE2:Hg19::chr14:60975644..60975673,+#_ecfd04328dbc1858f4a54ab6566836fa | p3@SIX6 |
| 2.1e-35 | FFCP PHASE1:Hg19::chr14:60975644..60975673,+#_ecfd04328dbc1858f4a54ab6566836fa | p3@SIX6 |
| 6.73e-35 | FFCP PHASE1:Hg19::chr14:60975871..60975880,+#_b667619d389e16440e0df704a6111017 | p4@SIX6 |
| 6.73e-35 | FFCP PHASE2:Hg19::chr14:60975871..60975880,+#_b667619d389e16440e0df704a6111017 | p4@SIX6 |
| 5.06e-34 | FFCP PHASE2:Hg19::chr11:31667372..31667383,-#_18ffff1fe424e6f2fd0db23784b561db | p@chr11:31667372..31667383, - |
| 5.06e-34 | FFCP PHASE1:Hg19::chr11:31667372..31667383,-#_18ffff1fe424e6f2fd0db23784b561db | p@chr11:31667372..31667383, - |
| 8.36e-34 | FFCP PHASE1:Hg19::chr19:1470631..1470648,-#_c565794f3731458029543f17abf2dd7c | p@chr19:1470631..1470648, - |
| 8.36e-34 | FFCP PHASE2:Hg19::chr19:1470631..1470648,-#_c565794f3731458029543f17abf2dd7c | p@chr19:1470631..1470648, - |
| 5.55e-33 | FFCP PHASE2:Hg19::chr21:44589135..44589151,+#_f116b67c433d1a304ceeb6a5798281d9 | p1@CRYAA |
| 5.55e-33 | FFCP PHASE1:Hg19::chr21:44589135..44589151,+#_f116b67c433d1a304ceeb6a5798281d9 | p1@CRYAA |
| 9.55e-33 | FFCP PHASE1:Hg19::chr17:27573875..27573878,+#_c49eb76f6d7eb493c2635a621848b8e0 | p1@CRYBA1 |
| 9.55e-33 | FFCP PHASE2:Hg19::chr17:27573875..27573878,+#_c49eb76f6d7eb493c2635a621848b8e0 | p1@CRYBA1 |
| 2.74e-29 | FFCP PHASE1:Hg19::chr2:45168589..45168601,-#_30d107272c71d65c16b93d74113a2c1d | p2@ENST00000456467 |
| 2.74e-29 | FFCP PHASE2:Hg19::chr2:45168589..45168601,-#_30d107272c71d65c16b93d74113a2c1d | p2@ENST00000456467 |
| 3.65e-29 | FFCP PHASE1:Hg19::chr7:107883678..107883689,-#_ddfba0cf2f5a356f553069d4a182aa1d | p13@NRCAM |
| 3.65e-29 | FFCP PHASE2:Hg19::chr7:107883678..107883689,-#_ddfba0cf2f5a356f553069d4a182aa1d | p13@NRCAM |
| 7.46e-29 | FFCP PHASE2:Hg19::chr13:114202163..114202178,+#_af43184cd4647f1b8ebd0fe4475f1c13 | p@chr13:114202163..114202178, + |
| 7.46e-29 | FFCP PHASE1:Hg19::chr13:114202163..114202178,+#_af43184cd4647f1b8ebd0fe4475f1c13 | p@chr13:114202163..114202178, + |
| 1.36e-28 | FFCP PHASE2:Hg19::chr3:173116225..173116242,+#_345e96d25105c6472013b99d83047a44 | p10@NLGN1 |
| 1.36e-28 | FFCP PHASE1:Hg19::chr3:173116225..173116242,+#_345e96d25105c6472013b99d83047a44 | p10@NLGN1 |
| 2.64e-27 | FFCP PHASE2:Hg19::chr2:45169233..45169244,+#_da7138f9e7914724712621f3962f7518 | p10@SIX3 |
| 2.64e-27 | FFCP PHASE1:Hg19::chr2:45169233..45169244,+#_da7138f9e7914724712621f3962f7518 | p10@SIX3 |
| 8.39e-27 | FFCP PHASE1:Hg19::chr14:60975858..60975869,+#_e353246972a352cc94b2e2f2291ce1af | p2@SIX6 |
| 8.39e-27 | FFCP PHASE2:Hg19::chr14:60975858..60975869,+#_e353246972a352cc94b2e2f2291ce1af | p2@SIX6 |
| 5.56e-26 | FFCP PHASE2:Hg19::chr19:40920692..40920700,-#_a75c40084224e74d564d4be148c2e894 | p@chr19:40920692..40920700, - |
| 5.56e-26 | FFCP PHASE1:Hg19::chr20:35861148..35861151,+#_a75c40084224e74d564d4be148c2e894 | p@chr20:35861148..35861151, + |
| 5.56e-26 | FFCP PHASE2:Hg19::chr3:150690809..150690822,-#_a75c40084224e74d564d4be148c2e894 | p3@CLRN1 |
| 5.56e-26 | FFCP PHASE1:Hg19::chr9:75848662..75848671,-#_a75c40084224e74d564d4be148c2e894 | p@chr9:75848662..75848671, - |
| 5.56e-26 | FFCP PHASE2:Hg19::chrX:43587410..43587413,+#_a75c40084224e74d564d4be148c2e894 | p@chrX:43587410..43587413, + |
| 5.56e-26 | FFCP PHASE1:Hg19::chr1:147374915..147374932,+#_a75c40084224e74d564d4be148c2e894 | p1@GJA8 |
| 5.56e-26 | FFCP PHASE2:Hg19::chr1:147374915..147374932,+#_a75c40084224e74d564d4be148c2e894 | p1@GJA8 |
| 5.56e-26 | FFCP PHASE1:Hg19::chr3:150690809..150690822,-#_a75c40084224e74d564d4be148c2e894 | p3@CLRN1 |
| 5.56e-26 | FFCP PHASE2:Hg19::chr20:35861148..35861151,+#_a75c40084224e74d564d4be148c2e894 | p@chr20:35861148..35861151, + |
| 5.56e-26 | FFCP PHASE1:Hg19::chrX:43587410..43587413,+#_a75c40084224e74d564d4be148c2e894 | p@chrX:43587410..43587413, + |
| 5.56e-26 | FFCP PHASE1:Hg19::chr19:40920692..40920700,-#_a75c40084224e74d564d4be148c2e894 | p@chr19:40920692..40920700, - |
| 5.56e-26 | FFCP PHASE2:Hg19::chr9:75848662..75848671,-#_a75c40084224e74d564d4be148c2e894 | p@chr9:75848662..75848671, - |
| 7.14e-26 | FFCP PHASE2:Hg19::chr10:73406056..73406065,+#_297ac642cc4885f144782f3b22386b45 | p@chr10:73406056..73406065, + |
| 7.14e-26 | FFCP PHASE2:Hg19::chr2:45154282..45154288,-#_297ac642cc4885f144782f3b22386b45 | p@chr2:45154282..45154288, - |
| 7.14e-26 | FFCP PHASE1:Hg19::chr3:156322310..156322314,-#_297ac642cc4885f144782f3b22386b45 | p@chr3:156322310..156322314, - |
| 7.14e-26 | FFCP PHASE1:Hg19::chr9:100057272..100057276,+#_297ac642cc4885f144782f3b22386b45 | p@chr9:100057272..100057276, + |
| 7.14e-26 | FFCP PHASE1:Hg19::chr7:123198284..123198329,-#_297ac642cc4885f144782f3b22386b45 | p3@NDUFA5 |
| 7.14e-26 | FFCP PHASE1:Hg19::chr21:44592626..44592635,-#_297ac642cc4885f144782f3b22386b45 | p5@CU686889 |
| 7.14e-26 | FFCP PHASE2:Hg19::chr21:44592788..44592807,+#_297ac642cc4885f144782f3b22386b45 | p@chr21:44592788..44592807, + |
| 7.14e-26 | FFCP PHASE2:Hg19::chr1:86064794..86064797,+#_297ac642cc4885f144782f3b22386b45 | p1@ENST00000426794 |
| 7.14e-26 | FFCP PHASE1:Hg19::chr16:17563573..17563582,+#_297ac642cc4885f144782f3b22386b45 | p@chr16:17563573..17563582, + |
| 7.14e-26 | FFCP PHASE1:Hg19::chr12:56848437..56848442,-#_297ac642cc4885f144782f3b22386b45 | p1@MIP |
| 7.14e-26 | FFCP PHASE1:Hg19::chr13:44875179..44875188,-#_297ac642cc4885f144782f3b22386b45 | p@chr13:44875179..44875188, - |
| 7.14e-26 | FFCP PHASE2:Hg19::chr1:115873480..115873484,+#_297ac642cc4885f144782f3b22386b45 | p@chr1:115873480..115873484, + |
| 7.14e-26 | FFCP PHASE2:Hg19::chr5:45038620..45038622,+#_297ac642cc4885f144782f3b22386b45 | p@chr5:45038620..45038622, + |
| 7.14e-26 | FFCP PHASE2:Hg19::chr5:124468141..124468176,-#_297ac642cc4885f144782f3b22386b45 | p@chr5:124468141..124468176, - |
| 7.14e-26 | FFCP PHASE2:Hg19::chr2:693025..693036,+#_297ac642cc4885f144782f3b22386b45 | p@chr2:693025..693036, + |
| 7.14e-26 | FFCP PHASE1:Hg19::chr16:85617064..85617073,-#_297ac642cc4885f144782f3b22386b45 | p@chr16:85617064..85617073, - |
| 7.14e-26 | FFCP PHASE2:Hg19::chr2:10538258..10538282,+#_297ac642cc4885f144782f3b22386b45 | p@chr2:10538258..10538282, + |
| 7.14e-26 | FFCP PHASE1:Hg19::chr2:45154282..45154288,-#_297ac642cc4885f144782f3b22386b45 | p@chr2:45154282..45154288, - |
| 7.14e-26 | FFCP PHASE1:Hg19::chr21:44592750..44592758,-#_297ac642cc4885f144782f3b22386b45 | p4@CU686889 |
| 7.14e-26 | FFCP PHASE1:Hg19::chr4:140656282..140656285,-#_297ac642cc4885f144782f3b22386b45 | p@chr4:140656282..140656285, - |
| 7.14e-26 | FFCP PHASE1:Hg19::chr11:65361417..65361421,-#_297ac642cc4885f144782f3b22386b45 | p2@KCNK7 |
| 7.14e-26 | FFCP PHASE1:Hg19::chr1:45769711..45769721,-#_297ac642cc4885f144782f3b22386b45 | p@chr1:45769711..45769721, - |
| 7.14e-26 | FFCP PHASE1:Hg19::chr19:41727698..41727705,+#_297ac642cc4885f144782f3b22386b45 | p@chr19:41727698..41727705, + |
| 7.14e-26 | FFCP PHASE2:Hg19::chr5:464155..464205,+#_297ac642cc4885f144782f3b22386b45 | p@chr5:464155..464205, + |
| 7.14e-26 | FFCP PHASE2:Hg19::chr16:85617064..85617073,-#_297ac642cc4885f144782f3b22386b45 | p@chr16:85617064..85617073, - |
| 7.14e-26 | FFCP PHASE1:Hg19::chr21:44592358..44592365,+#_297ac642cc4885f144782f3b22386b45 | p@chr21:44592358..44592365, + |
| 7.14e-26 | FFCP PHASE2:Hg19::chr21:44592512..44592521,+#_297ac642cc4885f144782f3b22386b45 | p@chr21:44592512..44592521, + |
| 7.14e-26 | FFCP PHASE1:Hg19::chr20:33903184..33903189,-#_297ac642cc4885f144782f3b22386b45 | p11@UQCC |
| 7.14e-26 | FFCP PHASE1:Hg19::chr5:124468141..124468176,-#_297ac642cc4885f144782f3b22386b45 | p@chr5:124468141..124468176, - |
| 7.14e-26 | FFCP PHASE2:Hg19::chr12:56848437..56848442,-#_297ac642cc4885f144782f3b22386b45 | p1@MIP |
| 7.14e-26 | FFCP PHASE2:Hg19::chr21:36253916..36253918,-#_297ac642cc4885f144782f3b22386b45 | p@chr21:36253916..36253918, - |
| 7.14e-26 | FFCP PHASE2:Hg19::chr8:94870047..94870056,+#_297ac642cc4885f144782f3b22386b45 | p30@PDP1 |
| 7.14e-26 | FFCP PHASE2:Hg19::chr13:44875179..44875188,-#_297ac642cc4885f144782f3b22386b45 | p@chr13:44875179..44875188, - |
| 7.14e-26 | FFCP PHASE1:Hg19::chr21:44592788..44592807,+#_297ac642cc4885f144782f3b22386b45 | p@chr21:44592788..44592807, + |
