MCL coexpression mm9:1965
From FANTOM5_SSTAR
Phase1 CAGE Peaks
| Short description | |
|---|---|
| Mm9::chr11:3831548..3831573,- | p@chr11:3831548..3831573 - |
| Mm9::chr11:3831591..3831602,- | p@chr11:3831591..3831602 - |
| Mm9::chr2:68224732..68224750,- | p7@Stk39 |
| Mm9::chr3:129457796..129457830,- | p@chr3:129457796..129457830 - |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0015889 | cobalamin transport | 0.0224360675481166 |
| GO:0015087 | cobalt ion transmembrane transporter activity | 0.0224360675481166 |
| GO:0051180 | vitamin transport | 0.0224360675481166 |
| GO:0006824 | cobalt ion transport | 0.0224360675481166 |
| GO:0031419 | cobalamin binding | 0.0224360675481166 |
| GO:0021940 | positive regulation of granule cell precursor proliferation | 0.0224360675481166 |
| GO:0021936 | regulation of granule cell precursor proliferation | 0.0224360675481166 |
| GO:0021534 | cell proliferation in hindbrain | 0.0224360675481166 |
| GO:0021924 | cell proliferation in the external granule layer | 0.0224360675481166 |
| GO:0021930 | granule cell precursor proliferation | 0.0224360675481166 |
| GO:0050897 | cobalt ion binding | 0.0224360675481166 |
| GO:0000186 | activation of MAPKK activity | 0.0224360675481166 |
| GO:0007173 | epidermal growth factor receptor signaling pathway | 0.0225917250643957 |
| GO:0006468 | protein amino acid phosphorylation | 0.032808170115595 |
| GO:0016310 | phosphorylation | 0.0366874167746968 |
| GO:0046915 | transition metal ion transmembrane transporter activity | 0.0366874167746968 |
| GO:0032147 | activation of protein kinase activity | 0.0395774152083312 |
| GO:0015082 | di-, tri-valent inorganic cation transmembrane transporter activity | 0.0395774152083312 |
| GO:0006793 | phosphorus metabolic process | 0.0395774152083312 |
| GO:0006796 | phosphate metabolic process | 0.0395774152083312 |
| GO:0050730 | regulation of peptidyl-tyrosine phosphorylation | 0.0395774152083312 |
| GO:0030902 | hindbrain development | 0.0429072138016966 |
| GO:0016324 | apical plasma membrane | 0.0429072138016966 |
| GO:0033238 | regulation of amine metabolic process | 0.0429072138016966 |
| GO:0001932 | regulation of protein amino acid phosphorylation | 0.0429072138016966 |
| GO:0006521 | regulation of amino acid metabolic process | 0.0429072138016966 |
| GO:0018212 | peptidyl-tyrosine modification | 0.0429072138016966 |
| GO:0042325 | regulation of phosphorylation | 0.0429072138016966 |
| GO:0018108 | peptidyl-tyrosine phosphorylation | 0.0429072138016966 |
| GO:0051174 | regulation of phosphorus metabolic process | 0.0429072138016966 |
| GO:0019220 | regulation of phosphate metabolic process | 0.0429072138016966 |
| GO:0048754 | branching morphogenesis of a tube | 0.0429072138016966 |
| GO:0000041 | transition metal ion transport | 0.0429072138016966 |
| GO:0001763 | morphogenesis of a branching structure | 0.0452229396790126 |
| GO:0016323 | basolateral plasma membrane | 0.0487933223552719 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>
| Ontology term | p-value | n |
|---|---|---|
| adult organism | 2.15e-07 | 51 |
| renal system | 3.73e-07 | 19 |
| urinary system structure | 3.81e-07 | 18 |
| kidney | 9.68e-07 | 14 |
| kidney mesenchyme | 9.68e-07 | 14 |
| upper urinary tract | 9.68e-07 | 14 |
| kidney rudiment | 9.68e-07 | 14 |
| kidney field | 9.68e-07 | 14 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
| MA0003.1 | 0.600426 |
| MA0004.1 | 0.6888 |
| MA0006.1 | 0.497533 |
| MA0007.1 | 0.672186 |
| MA0009.1 | 1.15569 |
| MA0014.1 | 0.581929 |
| MA0017.1 | 1.30949 |
| MA0019.1 | 0.964875 |
| MA0024.1 | 1.11019 |
| MA0025.1 | 1.39562 |
| MA0027.1 | 2.81824 |
| MA0028.1 | 3.23479 |
| MA0029.1 | 1.08753 |
| MA0030.1 | 1.09438 |
| MA0031.1 | 1.05719 |
| MA0038.1 | 0.846479 |
| MA0040.1 | 1.16866 |
| MA0041.1 | 0.604221 |
| MA0042.1 | 0.589368 |
| MA0043.1 | 1.25564 |
| MA0046.1 | 1.1929 |
| MA0048.1 | 0.266382 |
| MA0050.1 | 0.731539 |
| MA0051.1 | 0.856094 |
| MA0052.1 | 1.17701 |
| MA0055.1 | 0.790894 |
| MA0056.1 | 0 |
| MA0057.1 | 0.251896 |
| MA0058.1 | 0.581673 |
| MA0059.1 | 0.59559 |
| MA0060.1 | 0.403071 |
| MA0061.1 | 0.438628 |
| MA0063.1 | 0 |
| MA0066.1 | 0.834648 |
| MA0067.1 | 1.50873 |
| MA0068.1 | 0.713436 |
| MA0069.1 | 1.17737 |
| MA0070.1 | 1.16732 |
| MA0071.1 | 0.73062 |
| MA0072.1 | 1.15853 |
| MA0073.1 | 3.39973 |
| MA0074.1 | 0.795862 |
| MA0076.1 | 2.32565 |
| MA0077.1 | 1.13603 |
| MA0078.1 | 0.891476 |
| MA0081.1 | 0.621611 |
| MA0083.1 | 1.25482 |
| MA0084.1 | 1.84013 |
| MA0087.1 | 1.21037 |
| MA0088.1 | 0.582815 |
| MA0089.1 | 0 |
| MA0090.1 | 0.650768 |
| MA0091.1 | 0.703314 |
| MA0092.1 | 0.651119 |
| MA0093.1 | 0.519148 |
| MA0095.1 | 0 |
| MA0098.1 | 0 |
| MA0100.1 | 0.783305 |
| MA0101.1 | 0.605676 |
| MA0103.1 | 0.540576 |
| MA0105.1 | 0.313353 |
| MA0106.1 | 0.899777 |
| MA0107.1 | 0.533522 |
| MA0108.2 | 0.989014 |
| MA0109.1 | 0 |
| MA0111.1 | 0.666525 |
| MA0113.1 | 0.869608 |
| MA0114.1 | 2.89957 |
| MA0115.1 | 1.25852 |
| MA0116.1 | 0.497293 |
| MA0117.1 | 1.22527 |
| MA0119.1 | 2.50824 |
| MA0122.1 | 1.24573 |
| MA0124.1 | 1.45461 |
| MA0125.1 | 1.37907 |
| MA0130.1 | 0 |
| MA0131.1 | 0.960068 |
| MA0132.1 | 0 |
| MA0133.1 | 0 |
| MA0135.1 | 1.29308 |
| MA0136.1 | 0.817395 |
| MA0139.1 | 0.365453 |
| MA0140.1 | 1.84211 |
| MA0141.1 | 1.38335 |
| MA0142.1 | 1.04199 |
| MA0143.1 | 0.887119 |
| MA0144.1 | 0.439506 |
| MA0145.1 | 0.21199 |
| MA0146.1 | 0.0944145 |
| MA0147.1 | 0.453952 |
| MA0148.1 | 0.706718 |
| MA0149.1 | 3.6869 |
| MA0062.2 | 3.24307 |
| MA0035.2 | 1.85264 |
| MA0039.2 | 0.0220513 |
| MA0138.2 | 0.951653 |
| MA0002.2 | 0.368961 |
| MA0137.2 | 0.559766 |
| MA0104.2 | 0.386166 |
| MA0047.2 | 0.845655 |
| MA0112.2 | 0.211985 |
| MA0065.2 | 0.609584 |
| MA0150.1 | 0.67206 |
| MA0151.1 | 0 |
| MA0152.1 | 0.84577 |
| MA0153.1 | 1.31015 |
| MA0154.1 | 0.263609 |
| MA0155.1 | 0.230016 |
| MA0156.1 | 0.549102 |
| MA0157.1 | 1.0083 |
| MA0158.1 | 0 |
| MA0159.1 | 0.465802 |
| MA0160.1 | 0.71003 |
| MA0161.1 | 0 |
| MA0162.1 | 0.10667 |
| MA0163.1 | 0.672192 |
| MA0164.1 | 0.817786 |
| MA0080.2 | 0.534538 |
| MA0018.2 | 0.828253 |
| MA0099.2 | 0.944966 |
| MA0079.2 | 1.04582 |
| MA0102.2 | 1.8929 |
| MA0258.1 | 0.419871 |
| MA0259.1 | 0.441366 |
| MA0442.1 | 0 |
