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MCL coexpression mm9:2257

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Phase1 CAGE Peaks

 Short description
Mm9::chr19:32832066..32832077,+p2@Pten
Mm9::chr19:32832094..32832127,+p1@Pten
Mm9::chr19:32894609..32894613,+p@chr19:32894609..32894613
+
Mm9::chr3:99966377..99966459,+p1@Gdap2


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0016314phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity0.00476633977976223
GO:0051898negative regulation of protein kinase B signaling cascade0.00748996251105494
GO:0051896regulation of protein kinase B signaling cascade0.00748996251105494
GO:0043542endothelial cell migration0.00748996251105494
GO:0048738cardiac muscle development0.00748996251105494
GO:0042577lipid phosphatase activity0.00748996251105494
GO:0043491protein kinase B signaling cascade0.00748996251105494
GO:0004437inositol or phosphatidylinositol phosphatase activity0.0178737741741084
GO:0008138protein tyrosine/serine/threonine phosphatase activity0.0185357658101864
GO:0009968negative regulation of signal transduction0.0314225363258399
GO:0006470protein amino acid dephosphorylation0.0314225363258399
GO:0045786negative regulation of progression through cell cycle0.0314225363258399
GO:0008285negative regulation of cell proliferation0.0314225363258399
GO:0016311dephosphorylation0.0314225363258399
GO:0014706striated muscle development0.0314225363258399
GO:0006917induction of apoptosis0.0314225363258399
GO:0012502induction of programmed cell death0.0314225363258399
GO:0001525angiogenesis0.0314225363258399
GO:0004721phosphoprotein phosphatase activity0.0314225363258399
GO:0043066negative regulation of apoptosis0.0314225363258399
GO:0043069negative regulation of programmed cell death0.0314225363258399
GO:0043065positive regulation of apoptosis0.0314225363258399
GO:0043068positive regulation of programmed cell death0.0314225363258399
GO:0007517muscle development0.0314225363258399
GO:0007507heart development0.0314225363258399
GO:0048514blood vessel morphogenesis0.0314225363258399
GO:0000074regulation of progression through cell cycle0.0314225363258399
GO:0048646anatomical structure formation0.0316621142512777
GO:0001568blood vessel development0.0327288664877007
GO:0001944vasculature development0.0327288664877007
GO:0007243protein kinase cascade0.0333643784583356
GO:0016791phosphoric monoester hydrolase activity0.0333643784583356
GO:0007417central nervous system development0.0333643784583356
GO:0016477cell migration0.0382709047022085
GO:0042578phosphoric ester hydrolase activity0.038811623920921
GO:0042127regulation of cell proliferation0.0404527812077256
GO:0051674localization of cell0.0404527812077256
GO:0006928cell motility0.0404527812077256
GO:0009966regulation of signal transduction0.0404527812077256
GO:0051726regulation of cell cycle0.0417054730729195
GO:0042981regulation of apoptosis0.0427835737373896
GO:0043067regulation of programmed cell death0.0427835737373896



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
adult organism4.87e-0851
occipital lobe8.53e-0710
visual cortex8.53e-0710
neocortex8.53e-0710


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.331308
MA0004.10.6888
MA0006.10.497533
MA0007.10.672186
MA0009.11.15569
MA0014.12.62764
MA0017.10.528196
MA0019.10.964875
MA0024.11.11019
MA0025.11.39562
MA0027.12.81824
MA0028.10.509589
MA0029.11.08753
MA0030.11.09438
MA0031.11.05719
MA0038.10.846479
MA0040.11.16866
MA0041.10.604221
MA0042.10.589368
MA0043.11.25564
MA0046.11.1929
MA0048.10.735223
MA0050.10.731539
MA0051.10.856094
MA0052.11.17701
MA0055.10.396346
MA0056.10
MA0057.10.701847
MA0058.10.581673
MA0059.10.59559
MA0060.10.403071
MA0061.10.438628
MA0063.10
MA0066.10.834648
MA0067.11.50873
MA0068.10.256913
MA0069.11.17737
MA0070.11.16732
MA0071.10.73062
MA0072.11.15853
MA0073.10.783927
MA0074.10.795862
MA0076.10.550092
MA0077.11.13603
MA0078.10.891476
MA0081.10.621611
MA0083.11.25482
MA0084.11.84013
MA0087.11.21037
MA0088.10.582815
MA0089.10
MA0090.10.650768
MA0091.10.703314
MA0092.10.651119
MA0093.10.519148
MA0095.10
MA0098.10
MA0100.10.783305
MA0101.11.47308
MA0103.10.540576
MA0105.10.313353
MA0106.10.899777
MA0107.10.533522
MA0108.20.989014
MA0109.10
MA0111.10.666525
MA0113.10.869608
MA0114.10.43587
MA0115.11.25852
MA0116.10.497293
MA0117.11.22527
MA0119.10.606338
MA0122.11.24573
MA0124.11.45461
MA0125.11.37907
MA0130.10
MA0131.10.960068
MA0132.10
MA0133.10
MA0135.11.29308
MA0136.10.817395
MA0139.10.365453
MA0140.10.78318
MA0141.10.563066
MA0142.11.04199
MA0143.10.887119
MA0144.10.439506
MA0145.10.21199
MA0146.11.5929
MA0147.10.453952
MA0148.10.706718
MA0149.10.611881
MA0062.21.54479
MA0035.20.788288
MA0039.22.41467
MA0138.20.951653
MA0002.20.368961
MA0137.20.559766
MA0104.20.386166
MA0047.20.845655
MA0112.22.52766
MA0065.20.212467
MA0150.10.67206
MA0151.10
MA0152.10.84577
MA0153.11.31015
MA0154.10.263609
MA0155.10.230016
MA0156.10.549102
MA0157.11.0083
MA0158.10
MA0159.10.465802
MA0160.10.71003
MA0161.10
MA0162.10.346529
MA0163.10.672192
MA0164.10.817786
MA0080.20.534538
MA0018.20.828253
MA0099.20.944966
MA0079.23.82506
MA0102.21.8929
MA0258.10.419871
MA0259.10.441366
MA0442.10
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