Novel motif:140

name:	motif140_WTAAATAACG

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0007100	mitotic centrosome separation	4.622459e-10
GO:0070194	synaptonemal complex disassembly	9.230972e-9
GO:0031662	positive regulation of cyclin-dependent protein kinase activity involved in G2/M	9.230972e-9
GO:0006742	NADP catabolic process	2.336886e-8
GO:0009435	NAD biosynthetic process	9.175652e-8
GO:0019359	nicotinamide nucleotide biosynthetic process	1.274022e-7
GO:0051299	centrosome separation	1.467316e-7
GO:0002158	osteoclast proliferation	1.927680e-7
GO:0050884	neuromuscular process controlling posture	1.930931e-7
GO:0072526	pyridine-containing compound catabolic process	4.213528e-7
GO:0060613	fat pad development	6.684728e-7
GO:0019674	NAD metabolic process	7.763424e-7
GO:0033211	adiponectin-mediated signaling pathway	1.431613e-6
GO:0019363	pyridine nucleotide biosynthetic process	1.795835e-6
GO:0006769	nicotinamide metabolic process	2.458958e-6
GO:0020028	hemoglobin import	3.470459e-6
GO:0043044	ATP-dependent chromatin remodeling	6.857070e-6
GO:0010831	positive regulation of myotube differentiation	1.039819e-5
GO:0042904	9-cis-retinoic acid biosynthetic process	1.149465e-5
GO:0009820	alkaloid metabolic process	1.493668e-5
GO:0070886	positive regulation of calcineurin-NFAT signaling pathway	1.514078e-5
GO:0001561	fatty acid alpha-oxidation	1.668360e-5
GO:0048806	genitalia development	2.303740e-5
GO:0007412	axon target recognition	2.353655e-5
GO:0007141	male meiosis I	2.706717e-5
GO:0007140	male meiosis	2.706921e-5
GO:0090307	spindle assembly involved in mitosis	2.833097e-5
GO:0030539	male genitalia development	3.711927e-5
GO:0042362	fat-soluble vitamin biosynthetic process	3.851011e-5
GO:0006888	ER to Golgi vesicle-mediated transport	4.409729e-5
GO:0051935	glutamate uptake involved in synaptic transmission	5.087976e-5
GO:0046496	nicotinamide nucleotide metabolic process	5.188546e-5
GO:0021517	ventral spinal cord development	5.343246e-5
GO:0045653	negative regulation of megakaryocyte differentiation	6.533096e-5
GO:0010994	free ubiquitin chain polymerization	7.575427e-5
GO:0046546	development of primary male sexual characteristics	1.130547e-4
GO:0019362	pyridine nucleotide metabolic process	1.289292e-4
GO:0044255	cellular lipid metabolic process	1.345739e-4
GO:0033152	immunoglobulin V(D)J recombination	1.469916e-4
GO:0019227	neuronal action potential propagation	1.615276e-4
GO:0070193	synaptonemal complex organization	1.712534e-4
GO:0032235	negative regulation of calcium ion transport via store-operated calcium channel activity	1.762393e-4
GO:0002639	positive regulation of immunoglobulin production	1.817691e-4
GO:0070884	regulation of calcineurin-NFAT signaling pathway	1.855498e-4
GO:0006957	complement activation, alternative pathway	1.979143e-4
GO:0035455	response to interferon-alpha	1.984574e-4
GO:0007628	adult walking behavior	2.322999e-4
GO:0046661	male sex differentiation	2.502609e-4
GO:0007041	lysosomal transport	2.640389e-4
GO:0051938	L-glutamate import	2.646398e-4
GO:0044249	cellular biosynthetic process	3.014209e-4
GO:0042573	retinoic acid metabolic process	3.285180e-4
GO:0002329	pre-B cell differentiation	3.414287e-4
GO:0034723	DNA replication-dependent nucleosome organization	3.890723e-4
GO:0051964	negative regulation of synapse assembly	4.063990e-4
GO:0006733	oxidoreduction coenzyme metabolic process	4.074854e-4
GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process	4.241348e-4
GO:0007040	lysosome organization	4.718096e-4
GO:0007219	Notch signaling pathway	5.324993e-4
GO:0009058	biosynthetic process	5.526772e-4
GO:0043603	cellular amide metabolic process	6.545475e-4
GO:0016447	somatic recombination of immunoglobulin gene segments	6.633591e-4
GO:0043092	L-amino acid import	6.680479e-4
GO:0033577	protein glycosylation in endoplasmic reticulum	6.888884e-4
GO:0007034	vacuolar transport	7.088812e-4
GO:2001016	positive regulation of skeletal muscle cell differentiation	7.317985e-4
GO:0035640	exploration behavior	8.012525e-4
GO:0021523	somatic motor neuron differentiation	8.500591e-4
GO:0010165	response to X-ray	8.602370e-4
GO:0006325	chromatin organization	8.715572e-4
GO:0035810	positive regulation of urine volume	8.805232e-4
GO:0009110	vitamin biosynthetic process	9.347345e-4
GO:0010761	fibroblast migration	9.595608e-4
GO:0042359	vitamin D metabolic process	1.010826e-3
GO:0051769	regulation of nitric-oxide synthase biosynthetic process	1.048710e-3
GO:0043090	amino acid import	1.049618e-3
GO:0034725	DNA replication-dependent nucleosome disassembly	1.088854e-3
GO:0042448	progesterone metabolic process	1.091420e-3
GO:0060052	neurofilament cytoskeleton organization	1.125902e-3
GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis	1.133456e-3
GO:0051961	negative regulation of nervous system development	1.198741e-3
GO:0008610	lipid biosynthetic process	1.225152e-3
GO:0010807	regulation of synaptic vesicle priming	1.248377e-3
GO:0055114	oxidation-reduction process	1.284700e-3
GO:0042572	retinol metabolic process	1.313669e-3
GO:0001306	age-dependent response to oxidative stress	1.318548e-3
GO:0060612	adipose tissue development	1.378067e-3
GO:0016445	somatic diversification of immunoglobulins	1.422607e-3
GO:0010458	exit from mitosis	1.425002e-3
GO:0046513	ceramide biosynthetic process	1.436363e-3
GO:2000833	positive regulation of steroid hormone secretion	1.487172e-3
GO:0046434	organophosphate catabolic process	1.495763e-3
GO:0006629	lipid metabolic process	1.504446e-3
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	1.539151e-3
GO:0022613	ribonucleoprotein complex biogenesis	1.540946e-3
GO:0002540	leukotriene production involved in inflammatory response	1.571071e-3
GO:0033688	regulation of osteoblast proliferation	1.622476e-3
GO:0030325	adrenal gland development	1.731544e-3
GO:0042694	muscle cell fate specification	1.757981e-3
GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin	1.812756e-3
GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process	1.819185e-3
GO:0045104	intermediate filament cytoskeleton organization	1.869887e-3
GO:0002702	positive regulation of production of molecular mediator of immune response	1.893186e-3
GO:0008333	endosome to lysosome transport	1.972952e-3
GO:0007052	mitotic spindle organization	1.972952e-3
GO:0015813	L-glutamate transport	1.998189e-3
GO:0051488	activation of anaphase-promoting complex activity	2.124024e-3
GO:0045056	transcytosis	2.320432e-3
GO:0000160	two-component signal transduction system (phosphorelay)	2.322358e-3
GO:2000831	regulation of steroid hormone secretion	2.368439e-3
GO:0006766	vitamin metabolic process	2.397212e-3
GO:0045103	intermediate filament-based process	2.421716e-3
GO:0042438	melanin biosynthetic process	2.432439e-3
GO:0008209	androgen metabolic process	2.476251e-3
GO:0015800	acidic amino acid transport	2.525615e-3
GO:0035809	regulation of urine volume	2.585044e-3
GO:0046520	sphingoid biosynthetic process	2.680303e-3
GO:0007406	negative regulation of neuroblast proliferation	2.746297e-3
GO:0034622	cellular macromolecular complex assembly	2.801305e-3
GO:0006338	chromatin remodeling	2.843974e-3
GO:0002053	positive regulation of mesenchymal cell proliferation	2.894578e-3
GO:0032787	monocarboxylic acid metabolic process	2.922104e-3
GO:0035725	sodium ion transmembrane transport	2.976496e-3
GO:0001667	ameboidal cell migration	2.986145e-3
GO:0048266	behavioral response to pain	3.160128e-3
GO:0009268	response to pH	3.188527e-3
GO:0071843	cellular component biogenesis at cellular level	3.194772e-3
GO:0022618	ribonucleoprotein complex assembly	3.208750e-3
GO:0000395	nuclear mRNA 5'-splice site recognition	3.305972e-3
GO:0001523	retinoid metabolic process	3.310682e-3
GO:0006927	transformed cell apoptosis	3.735950e-3
GO:0048193	Golgi vesicle transport	3.739404e-3
GO:2000794	regulation of epithelial cell proliferation involved in lung morphogenesis	3.853952e-3
GO:0051155	positive regulation of striated muscle cell differentiation	4.012407e-3
GO:0061136	regulation of proteasomal protein catabolic process	4.023886e-3
GO:0006426	glycyl-tRNA aminoacylation	4.084660e-3
GO:0044264	cellular polysaccharide metabolic process	4.208376e-3
GO:0016101	diterpenoid metabolic process	4.231021e-3
GO:0071826	ribonucleoprotein complex subunit organization	4.261468e-3
GO:0051276	chromosome organization	4.285978e-3
GO:0043128	positive regulation of 1-phosphatidylinositol 4-kinase activity	4.366986e-3
GO:0007094	mitotic cell cycle spindle assembly checkpoint	4.456641e-3
GO:0016568	chromatin modification	4.609002e-3
GO:0007223	Wnt receptor signaling pathway, calcium modulating pathway	4.652344e-3
GO:0060685	regulation of prostatic bud formation	4.652344e-3
GO:0051464	positive regulation of cortisol secretion	4.658095e-3
GO:0042322	negative regulation of circadian sleep/wake cycle, REM sleep	4.658095e-3
GO:0071173	spindle assembly checkpoint	4.691868e-3
GO:0071174	mitotic cell cycle spindle checkpoint	4.739988e-3
GO:0060021	palate development	4.758213e-3
GO:0030148	sphingolipid biosynthetic process	4.829204e-3
GO:0034621	cellular macromolecular complex subunit organization	4.850844e-3
GO:0002541	activation of plasma proteins involved in acute inflammatory response	4.957927e-3
GO:0032438	melanosome organization	5.060534e-3
GO:0000387	spliceosomal snRNP assembly	5.060534e-3
GO:0045841	negative regulation of mitotic metaphase/anaphase transition	5.087048e-3
GO:0031577	spindle checkpoint	5.138108e-3
GO:0051151	negative regulation of smooth muscle cell differentiation	5.223998e-3
GO:0006582	melanin metabolic process	5.252402e-3
GO:0006613	cotranslational protein targeting to membrane	5.326907e-3
GO:0007286	spermatid development	5.341681e-3
GO:0060028	convergent extension involved in axis elongation	5.583523e-3
GO:0006776	vitamin A metabolic process	5.780495e-3
GO:0008207	C21-steroid hormone metabolic process	5.791215e-3
GO:0007098	centrosome cycle	5.836548e-3
GO:0010841	positive regulation of circadian sleep/wake cycle, wakefulness	5.909167e-3
GO:0016055	Wnt receptor signaling pathway	6.101253e-3
GO:0048515	spermatid differentiation	6.203448e-3
GO:0007256	activation of JNKK activity	6.234446e-3
GO:0015991	ATP hydrolysis coupled proton transport	6.437799e-3
GO:0019637	organophosphate metabolic process	6.470012e-3
GO:0010629	negative regulation of gene expression	6.486525e-3
GO:0016070	RNA metabolic process	6.493101e-3
GO:0008054	cyclin catabolic process	6.542995e-3
GO:0045749	negative regulation of S phase of mitotic cell cycle	6.557283e-3
GO:0032413	negative regulation of ion transmembrane transporter activity	6.664898e-3
GO:0007096	regulation of exit from mitosis	6.761854e-3
GO:0031536	positive regulation of exit from mitosis	6.860486e-3
GO:0072273	metanephric nephron morphogenesis	6.914644e-3
GO:0010464	regulation of mesenchymal cell proliferation	6.954302e-3
GO:0001504	neurotransmitter uptake	6.976340e-3
GO:0045292	nuclear mRNA cis splicing, via spliceosome	7.022604e-3
GO:0045861	negative regulation of proteolysis	7.456798e-3
GO:0048265	response to pain	7.462349e-3
GO:0045737	positive regulation of cyclin-dependent protein kinase activity	7.629456e-3
GO:2000063	positive regulation of ureter smooth muscle cell differentiation	7.663500e-3
GO:2000357	negative regulation of kidney smooth muscle cell differentiation	7.663500e-3
GO:2000062	negative regulation of ureter smooth muscle cell differentiation	7.663500e-3
GO:2000358	positive regulation of kidney smooth muscle cell differentiation	7.663500e-3
GO:2000729	positive regulation of mesenchymal cell proliferation involved in ureter development	7.663500e-3
GO:0046534	positive regulation of photoreceptor cell differentiation	7.663500e-3
GO:0007502	digestive tract mesoderm development	7.663500e-3
GO:0014858	positive regulation of skeletal muscle cell proliferation	7.663500e-3
GO:0060782	regulation of mesenchymal cell proliferation involved in prostate gland development	7.663500e-3
GO:0060783	mesenchymal smoothened signaling pathway involved in prostate gland development	7.663500e-3
GO:0080125	multicellular structure septum development	7.663500e-3
GO:0006721	terpenoid metabolic process	7.804795e-3
GO:0048521	negative regulation of behavior	7.847610e-3
GO:0043438	acetoacetic acid metabolic process	7.867215e-3
GO:2000173	negative regulation of branching morphogenesis of a nerve	8.039182e-3
GO:0002562	somatic diversification of immune receptors via germline recombination within a single locus	8.103826e-3
GO:2000976	regulation of transcription from RNA polymerase II promoter involved in detection of glucose	8.423000e-3
GO:0000433	negative regulation of transcription from RNA polymerase II promoter by glucose	8.423000e-3
GO:2000971	negative regulation of detection of glucose	8.423000e-3
GO:0010605	negative regulation of macromolecule metabolic process	8.519293e-3
GO:0015986	ATP synthesis coupled proton transport	8.672831e-3
GO:0035457	cellular response to interferon-alpha	8.769157e-3
GO:0051462	regulation of cortisol secretion	8.814899e-3
GO:0003401	axis elongation	9.021047e-3
GO:0044237	cellular metabolic process	9.083386e-3
GO:0071841	cellular component organization or biogenesis at cellular level	9.141657e-3
GO:0016188	synaptic vesicle maturation	9.146166e-3
GO:0002543	activation of blood coagulation via clotting cascade	9.214822e-3
GO:0048753	pigment granule organization	9.543850e-3
GO:0007051	spindle organization	9.545359e-3
GO:0016539	intein-mediated protein splicing	9.622711e-3
GO:0003140	determination of left/right asymmetry in lateral mesoderm	9.622711e-3
GO:0043589	skin morphogenesis	9.642498e-3
GO:2000300	regulation of synaptic vesicle exocytosis	9.729217e-3
GO:0010830	regulation of myotube differentiation	9.813741e-3
GO:0050850	positive regulation of calcium-mediated signaling	9.942642e-3
GO:0034080	CenH3-containing nucleosome assembly at centromere	1.021461e-2
GO:0046467	membrane lipid biosynthetic process	1.030480e-2
GO:0032289	central nervous system myelin formation	1.046217e-2
GO:0090009	primitive streak formation	1.048765e-2
GO:0030071	regulation of mitotic metaphase/anaphase transition	1.074482e-2
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	1.080796e-2
GO:0006767	water-soluble vitamin metabolic process	1.093818e-2
GO:0060029	convergent extension involved in organogenesis	1.095899e-2
GO:0032237	activation of store-operated calcium channel activity	1.095899e-2
GO:0060993	kidney morphogenesis	1.108828e-2
GO:0007257	activation of JUN kinase activity	1.111038e-2
GO:0002200	somatic diversification of immune receptors	1.118693e-2
GO:0003338	metanephros morphogenesis	1.127735e-2
GO:0007228	positive regulation of hh target transcription factor activity	1.133282e-2
GO:0045602	negative regulation of endothelial cell differentiation	1.133282e-2
GO:0001705	ectoderm formation	1.133282e-2
GO:0019605	butyrate metabolic process	1.138792e-2
GO:0033151	V(D)J recombination	1.142823e-2
GO:0007033	vacuole organization	1.177409e-2
GO:0046813	virion attachment, binding of host cell surface receptor	1.177971e-2
GO:0032410	negative regulation of transporter activity	1.192189e-2
GO:0050718	positive regulation of interleukin-1 beta secretion	1.192353e-2
GO:0000186	activation of MAPKK activity	1.205697e-2
GO:0060447	bud outgrowth involved in lung branching	1.223423e-2
GO:0033132	negative regulation of glucokinase activity	1.223423e-2
GO:0016264	gap junction assembly	1.227450e-2
GO:0045014	negative regulation of transcription by glucose	1.269633e-2
GO:0006528	asparagine metabolic process	1.269633e-2
GO:0010467	gene expression	1.283650e-2
GO:0072001	renal system development	1.283999e-2
GO:0006631	fatty acid metabolic process	1.301338e-2
GO:0035264	multicellular organism growth	1.306887e-2
GO:0045839	negative regulation of mitosis	1.328795e-2
GO:0045137	development of primary sexual characteristics	1.336416e-2
GO:0065003	macromolecular complex assembly	1.366980e-2
GO:0070527	platelet aggregation	1.367665e-2
GO:0009062	fatty acid catabolic process	1.375436e-2
GO:0006672	ceramide metabolic process	1.376261e-2
GO:0008299	isoprenoid biosynthetic process	1.392900e-2
GO:0060459	left lung development	1.412757e-2
GO:0042953	lipoprotein transport	1.418482e-2
GO:0050716	positive regulation of interleukin-1 secretion	1.430381e-2
GO:0031055	chromatin remodeling at centromere	1.430381e-2
GO:0003006	developmental process involved in reproduction	1.433983e-2
GO:0031047	gene silencing by RNA	1.438794e-2
GO:0060026	convergent extension	1.447238e-2
GO:0002377	immunoglobulin production	1.457273e-2
GO:0009165	nucleotide biosynthetic process	1.489869e-2
GO:0061002	negative regulation of dendritic spine morphogenesis	1.511864e-2
GO:0045652	regulation of megakaryocyte differentiation	1.533405e-2
GO:0051188	cofactor biosynthetic process	1.550507e-2
GO:0006351	transcription, DNA-dependent	1.553180e-2
GO:0061056	sclerotome development	1.562509e-2
GO:0009987	cellular process	1.598072e-2
GO:0009108	coenzyme biosynthetic process	1.615545e-2
GO:0060285	ciliary cell motility	1.665955e-2
GO:0008628	induction of apoptosis by hormones	1.665955e-2
GO:0045329	carnitine biosynthetic process	1.665955e-2
GO:0060676	ureteric bud formation	1.674363e-2
GO:0010259	multicellular organismal aging	1.705365e-2
GO:0009791	post-embryonic development	1.718677e-2
GO:0010948	negative regulation of cell cycle process	1.738989e-2
GO:2000113	negative regulation of cellular macromolecule biosynthetic process	1.748996e-2
GO:0015807	L-amino acid transport	1.754017e-2
GO:0007411	axon guidance	1.771410e-2
GO:0008584	male gonad development	1.771744e-2
GO:0072210	metanephric nephron development	1.778696e-2
GO:0048745	smooth muscle tissue development	1.778696e-2
GO:0072329	monocarboxylic acid catabolic process	1.787087e-2
GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway	1.826438e-2
GO:0019752	carboxylic acid metabolic process	1.867121e-2
GO:0060157	urinary bladder development	1.869573e-2
GO:0006386	termination of RNA polymerase III transcription	1.869573e-2
GO:0006385	transcription elongation from RNA polymerase III promoter	1.869573e-2
GO:0006082	organic acid metabolic process	1.876412e-2
GO:0007019	microtubule depolymerization	1.881328e-2
GO:0021904	dorsal/ventral neural tube patterning	1.889977e-2
GO:0021510	spinal cord development	1.890786e-2
GO:0046459	short-chain fatty acid metabolic process	1.898445e-2
GO:0072028	nephron morphogenesis	1.905669e-2
GO:0072136	metanephric mesenchymal cell proliferation involved in metanephros development	1.936908e-2
GO:0007254	JNK cascade	1.938182e-2
GO:0018191	peptidyl-serine octanoylation	1.945300e-2
GO:0014047	glutamate secretion	1.984747e-2
GO:0021938	smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation	1.993172e-2
GO:0034645	cellular macromolecule biosynthetic process	2.017060e-2
GO:0007548	sex differentiation	2.030855e-2
GO:0033628	regulation of cell adhesion mediated by integrin	2.038688e-2
GO:0072199	regulation of mesenchymal cell proliferation involved in ureter development	2.050116e-2
GO:0043933	macromolecular complex subunit organization	2.061171e-2
GO:0033630	positive regulation of cell adhesion mediated by integrin	2.075317e-2
GO:0000723	telomere maintenance	2.093615e-2
GO:0033555	multicellular organismal response to stress	2.129603e-2
GO:0006739	NADP metabolic process	2.139486e-2
GO:0032851	positive regulation of Rab GTPase activity	2.141750e-2
GO:0070295	renal water absorption	2.166022e-2
GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	2.169398e-2
GO:0035270	endocrine system development	2.185380e-2
GO:0001708	cell fate specification	2.187418e-2
GO:0032229	negative regulation of synaptic transmission, GABAergic	2.200739e-2
GO:0016572	histone phosphorylation	2.249109e-2
GO:0030162	regulation of proteolysis	2.253728e-2
GO:0071318	cellular response to ATP	2.284585e-2
GO:0007442	hindgut morphogenesis	2.316496e-2
GO:0071842	cellular component organization at cellular level	2.329982e-2
GO:0042320	regulation of circadian sleep/wake cycle, REM sleep	2.344851e-2
GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter	2.344851e-2
GO:0009059	macromolecule biosynthetic process	2.350314e-2
GO:0009892	negative regulation of metabolic process	2.356673e-2
GO:0046519	sphingoid metabolic process	2.360653e-2
GO:0016339	calcium-dependent cell-cell adhesion	2.385098e-2
GO:0060769	positive regulation of epithelial cell proliferation involved in prostate gland development	2.405767e-2
GO:0048859	formation of anatomical boundary	2.405767e-2
GO:0007418	ventral midline development	2.405767e-2
GO:0042180	cellular ketone metabolic process	2.432860e-2
GO:0071840	cellular component organization or biogenesis	2.434866e-2
GO:0032774	RNA biosynthetic process	2.436341e-2
GO:0007266	Rho protein signal transduction	2.445866e-2
GO:0060324	face development	2.447316e-2
GO:0045444	fat cell differentiation	2.449423e-2
GO:2001014	regulation of skeletal muscle cell differentiation	2.454920e-2
GO:0060738	epithelial-mesenchymal signaling involved in prostate gland development	2.467327e-2
GO:0035092	sperm chromatin condensation	2.467327e-2
GO:0051225	spindle assembly	2.521614e-2
GO:0032236	positive regulation of calcium ion transport via store-operated calcium channel activity	2.527725e-2
GO:0051301	cell division	2.544397e-2
GO:0006260	DNA replication	2.557450e-2
GO:0042321	negative regulation of circadian sleep/wake cycle, sleep	2.592363e-2
GO:0000432	positive regulation of transcription from RNA polymerase II promoter by glucose	2.592363e-2
GO:0060441	epithelial tube branching involved in lung morphogenesis	2.597459e-2
GO:0007090	regulation of S phase of mitotic cell cycle	2.598240e-2
GO:0060292	long term synaptic depression	2.630632e-2
GO:0050706	regulation of interleukin-1 beta secretion	2.647106e-2
GO:0005977	glycogen metabolic process	2.682034e-2
GO:0034063	stress granule assembly	2.700467e-2
GO:0033092	positive regulation of immature T cell proliferation in thymus	2.719919e-2
GO:0035567	non-canonical Wnt receptor signaling pathway	2.721433e-2
GO:0042113	B cell activation	2.725862e-2
GO:0008344	adult locomotory behavior	2.759397e-2
GO:0032200	telomere organization	2.781603e-2
GO:0061349	planar cell polarity pathway involved in cardiac right atrium morphogenesis	2.784631e-2
GO:0061350	planar cell polarity pathway involved in cardiac muscle tissue morphogenesis	2.784631e-2
GO:0061354	planar cell polarity pathway involved in pericardium morphogenesis	2.784631e-2
GO:0061347	planar cell polarity pathway involved in outflow tract morphogenesis	2.784631e-2
GO:0051594	detection of glucose	2.784631e-2
GO:0060210	metestrus	2.784631e-2
GO:0061348	planar cell polarity pathway involved in ventricular septum morphogenesis	2.784631e-2
GO:0060325	face morphogenesis	2.793968e-2
GO:0007568	aging	2.814137e-2
GO:0006073	cellular glucan metabolic process	2.841420e-2
GO:0007289	spermatid nucleus differentiation	2.879358e-2
GO:0007018	microtubule-based movement	2.911583e-2
GO:0006488	dolichol-linked oligosaccharide biosynthetic process	2.951848e-2
GO:0060458	right lung development	2.982444e-2
GO:0048008	platelet-derived growth factor receptor signaling pathway	2.991774e-2
GO:0050704	regulation of interleukin-1 secretion	3.031140e-2
GO:0035641	locomotory exploration behavior	3.117337e-2
GO:0030202	heparin metabolic process	3.117337e-2
GO:0043486	histone exchange	3.138803e-2
GO:0034654	nucleobase-containing compound biosynthetic process	3.152036e-2
GO:0033189	response to vitamin A	3.156469e-2
GO:0055098	response to low-density lipoprotein particle stimulus	3.178325e-2
GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation	3.185675e-2
GO:0001655	urogenital system development	3.237277e-2
GO:0060067	cervix development	3.254601e-2
GO:0010558	negative regulation of macromolecule biosynthetic process	3.287558e-2
GO:0014043	negative regulation of neuron maturation	3.324111e-2
GO:0070979	protein K11-linked ubiquitination	3.332566e-2
GO:0033205	cell cycle cytokinesis	3.333663e-2
GO:0072376	protein activation cascade	3.333861e-2
GO:0002532	production of molecular mediator involved in inflammatory response	3.360804e-2
GO:0019748	secondary metabolic process	3.390961e-2
GO:0072092	ureteric bud invasion	3.394199e-2
GO:0060161	positive regulation of dopamine receptor signaling pathway	3.394199e-2
GO:0051297	centrosome organization	3.409476e-2
GO:0003014	renal system process	3.441007e-2
GO:0044085	cellular component biogenesis	3.469745e-2
GO:2000177	regulation of neural precursor cell proliferation	3.491647e-2
GO:0016197	endosome transport	3.494287e-2
GO:0060675	ureteric bud morphogenesis	3.497772e-2
GO:0048850	hypophysis morphogenesis	3.536096e-2
GO:0051261	protein depolymerization	3.536096e-2
GO:0035564	regulation of kidney size	3.536096e-2
GO:0051253	negative regulation of RNA metabolic process	3.537082e-2
GO:0060286	flagellar cell motility	3.537492e-2
GO:0019373	epoxygenase P450 pathway	3.537492e-2
GO:0043651	linoleic acid metabolic process	3.537492e-2
GO:2000027	regulation of organ morphogenesis	3.544797e-2
GO:0045494	photoreceptor cell maintenance	3.562375e-2
GO:0006353	transcription termination, DNA-dependent	3.594404e-2
GO:0070447	positive regulation of oligodendrocyte progenitor proliferation	3.607895e-2
GO:0045892	negative regulation of transcription, DNA-dependent	3.623941e-2
GO:0002440	production of molecular mediator of immune response	3.664007e-2
GO:0050848	regulation of calcium-mediated signaling	3.669505e-2
GO:0003097	renal water transport	3.680255e-2
GO:0022409	positive regulation of cell-cell adhesion	3.681545e-2
GO:0002637	regulation of immunoglobulin production	3.704412e-2
GO:0060323	head morphogenesis	3.714961e-2
GO:0006996	organelle organization	3.733316e-2
GO:0072093	metanephric renal vesicle formation	3.753172e-2
GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry	3.753172e-2
GO:0033131	regulation of glucokinase activity	3.753172e-2
GO:0019062	virion attachment to host cell surface receptor	3.753172e-2
GO:0031670	cellular response to nutrient	3.779676e-2
GO:0060322	head development	3.820015e-2
GO:0021891	olfactory bulb interneuron development	3.865239e-2
GO:0032414	positive regulation of ion transmembrane transporter activity	3.887371e-2
GO:0005980	glycogen catabolic process	3.892970e-2
GO:0051926	negative regulation of calcium ion transport	3.954899e-2
GO:0061290	canonical Wnt receptor signaling pathway involved in metanephric kidney development	3.975218e-2
GO:0048312	intracellular distribution of mitochondria	3.975218e-2
GO:0003344	pericardium morphogenesis	3.975218e-2
GO:0043369	CD4-positive or CD8-positive, alpha-beta T cell lineage commitment	3.975218e-2
GO:0090304	nucleic acid metabolic process	3.989387e-2
GO:0051597	response to methylmercury	3.993669e-2
GO:2000178	negative regulation of neural precursor cell proliferation	4.048841e-2
GO:0060516	primary prostatic bud elongation	4.050318e-2
GO:0046015	regulation of transcription by glucose	4.050318e-2
GO:0001822	kidney development	4.092529e-2
GO:0009109	coenzyme catabolic process	4.112170e-2
GO:0003341	cilium movement	4.125953e-2
GO:0002741	positive regulation of cytokine secretion involved in immune response	4.125953e-2
GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	4.202118e-2
GO:0044247	cellular polysaccharide catabolic process	4.240508e-2
GO:0009251	glucan catabolic process	4.240508e-2
GO:0043161	proteasomal ubiquitin-dependent protein catabolic process	4.248059e-2
GO:0060599	lateral sprouting involved in mammary gland duct morphogenesis	4.278810e-2
GO:0001302	replicative cell aging	4.278810e-2
GO:0007270	neuron-neuron synaptic transmission	4.297499e-2
GO:0048096	chromatin-mediated maintenance of transcription	4.301646e-2
GO:0035987	endodermal cell differentiation	4.301646e-2
GO:0090090	negative regulation of canonical Wnt receptor signaling pathway	4.313970e-2
GO:0048808	male genitalia morphogenesis	4.356024e-2
GO:0016255	attachment of GPI anchor to protein	4.356024e-2
GO:0060677	ureteric bud elongation	4.433756e-2
GO:0034660	ncRNA metabolic process	4.455516e-2
GO:0043004	cytoplasmic sequestering of CFTR protein	4.480390e-2
GO:0016043	cellular component organization	4.501966e-2
GO:0007398	ectoderm development	4.503903e-2
GO:0060406	positive regulation of penile erection	4.512002e-2
GO:0010498	proteasomal protein catabolic process	4.526848e-2
GO:0006139	nucleobase-containing compound metabolic process	4.562512e-2
GO:0060768	regulation of epithelial cell proliferation involved in prostate gland development	4.574807e-2
GO:0006654	phosphatidic acid biosynthetic process	4.590757e-2
GO:0003408	optic cup formation involved in camera-type eye development	4.590757e-2
GO:0071299	cellular response to vitamin A	4.598875e-2
GO:0032785	negative regulation of transcription elongation, DNA-dependent	4.670018e-2
GO:0006704	glucocorticoid biosynthetic process	4.749779e-2
GO:0034754	cellular hormone metabolic process	4.752489e-2
GO:0050679	positive regulation of epithelial cell proliferation	4.839668e-2
GO:0043507	positive regulation of JUN kinase activity	4.843305e-2
GO:0031327	negative regulation of cellular biosynthetic process	4.843750e-2
GO:0007598	blood coagulation, extrinsic pathway	4.910791e-2
GO:0061053	somite development	4.912357e-2
GO:0021781	glial cell fate commitment	4.950994e-2
GO:0003323	type B pancreatic cell development	4.952042e-2
GO:0001736	establishment of planar polarity	4.952042e-2
GO:2000484	positive regulation of interleukin-8 secretion	4.992032e-2
GO:0010508	positive regulation of autophagy	4.992032e-2
GO:0019395	fatty acid oxidation	5.019914e-2
GO:0006396	RNA processing	5.031784e-2
GO:0048016	inositol phosphate-mediated signaling	5.049592e-2
GO:0072075	metanephric mesenchyme development	5.097302e-2
GO:0060601	lateral sprouting from an epithelium	5.097302e-2
GO:0015711	organic anion transport	5.105594e-2
GO:0072088	nephron epithelium morphogenesis	5.122289e-2
GO:0034587	piRNA metabolic process	5.155965e-2
GO:0002011	morphogenesis of an epithelial sheet	5.195282e-2
GO:0045934	negative regulation of nucleobase-containing compound metabolic process	5.224386e-2
GO:0007193	inhibition of adenylate cyclase activity by G-protein signaling pathway	5.293081e-2
GO:0030534	adult behavior	5.320336e-2
GO:0046668	regulation of retinal cell programmed cell death	5.321805e-2
GO:0006112	energy reserve metabolic process	5.330834e-2
GO:0044283	small molecule biosynthetic process	5.331228e-2
GO:0046394	carboxylic acid biosynthetic process	5.333965e-2
GO:0048678	response to axon injury	5.334199e-2
GO:0015672	monovalent inorganic cation transport	5.341326e-2
GO:0006775	fat-soluble vitamin metabolic process	5.343700e-2
GO:0008380	RNA splicing	5.351883e-2

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0090273	regulation of somatostatin secretion	2.051119e-11
GO:0043044	ATP-dependent chromatin remodeling	1.396748e-8
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	2.822043e-8
GO:0031648	protein destabilization	7.759079e-8
GO:0048266	behavioral response to pain	1.875367e-7
GO:0048265	response to pain	4.299229e-7
GO:0007089	traversing start control point of mitotic cell cycle	5.432077e-7
GO:0034725	DNA replication-dependent nucleosome disassembly	8.369541e-7
GO:0007632	visual behavior	1.078022e-6
GO:0032412	regulation of ion transmembrane transporter activity	1.379964e-6
GO:0071844	cellular component assembly at cellular level	1.458791e-6
GO:0035845	photoreceptor cell outer segment organization	1.460867e-6
GO:0001662	behavioral fear response	1.499436e-6
GO:0002209	behavioral defense response	1.582473e-6
GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus	1.807623e-6
GO:0008542	visual learning	2.161056e-6
GO:0046381	CMP-N-acetylneuraminate metabolic process	2.354036e-6
GO:0000398	nuclear mRNA splicing, via spliceosome	2.789055e-6
GO:0022898	regulation of transmembrane transporter activity	3.345914e-6
GO:0002158	osteoclast proliferation	3.487901e-6
GO:0000375	RNA splicing, via transesterification reactions	3.852479e-6
GO:0042596	fear response	4.108850e-6
GO:0042593	glucose homeostasis	7.140406e-6
GO:0006376	mRNA splice site selection	7.918425e-6
GO:0006054	N-acetylneuraminate metabolic process	9.785336e-6
GO:0048002	antigen processing and presentation of peptide antigen	1.013308e-5
GO:0034621	cellular macromolecular complex subunit organization	1.103616e-5
GO:0032409	regulation of transporter activity	1.209552e-5
GO:0007212	dopamine receptor signaling pathway	1.397331e-5
GO:0060807	regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification	1.491920e-5
GO:0003142	cardiogenic plate morphogenesis	1.491920e-5
GO:0001828	inner cell mass cellular morphogenesis	1.491920e-5
GO:0007008	outer mitochondrial membrane organization	1.646627e-5
GO:0030317	sperm motility	2.249335e-5
GO:0060956	endocardial cell differentiation	2.765482e-5
GO:0010994	free ubiquitin chain polymerization	3.309978e-5
GO:0048026	positive regulation of nuclear mRNA splicing, via spliceosome	3.463988e-5
GO:0010458	exit from mitosis	3.736461e-5
GO:0051924	regulation of calcium ion transport	4.879357e-5
GO:0051925	regulation of calcium ion transport via voltage-gated calcium channel activity	5.137243e-5
GO:2000121	regulation of removal of superoxide radicals	5.339714e-5
GO:0045861	negative regulation of proteolysis	5.533959e-5
GO:0048866	stem cell fate specification	6.182292e-5
GO:0000245	spliceosome assembly	6.279175e-5
GO:0022607	cellular component assembly	6.780988e-5
GO:2000035	regulation of stem cell division	7.091225e-5
GO:0045844	positive regulation of striated muscle tissue development	7.291534e-5
GO:0071157	negative regulation of cell cycle arrest	7.865729e-5
GO:2000466	negative regulation of glycogen (starch) synthase activity	8.083275e-5
GO:0046415	urate metabolic process	9.741064e-5
GO:0031529	ruffle organization	1.010189e-4
GO:0021784	postganglionic parasympathetic nervous system development	1.032997e-4
GO:0060913	cardiac cell fate determination	1.032997e-4
GO:0010172	embryonic body morphogenesis	1.047289e-4
GO:0033555	multicellular organismal response to stress	1.098879e-4
GO:0016071	mRNA metabolic process	1.192367e-4
GO:0019882	antigen processing and presentation	1.196268e-4
GO:0048643	positive regulation of skeletal muscle tissue development	1.234021e-4
GO:0061031	endodermal digestive tract morphogenesis	1.294849e-4
GO:0048865	stem cell fate commitment	1.294849e-4
GO:0042662	negative regulation of mesodermal cell fate specification	1.440519e-4
GO:0043249	erythrocyte maturation	1.536760e-4
GO:0008306	associative learning	1.583657e-4
GO:2000043	regulation of cardiac cell fate specification	2.128761e-4
GO:0010959	regulation of metal ion transport	2.241234e-4
GO:0033120	positive regulation of RNA splicing	2.260981e-4
GO:2000500	positive regulation of induction of apoptosis in response to chemical stimulus	2.540473e-4
GO:2000836	positive regulation of androgen secretion	2.540473e-4
GO:0048250	mitochondrial iron ion transport	2.540473e-4
GO:0035260	internal genitalia morphogenesis	2.540473e-4
GO:0006338	chromatin remodeling	2.577139e-4
GO:0001714	endodermal cell fate specification	2.586919e-4
GO:0034765	regulation of ion transmembrane transport	2.996258e-4
GO:0045931	positive regulation of mitotic cell cycle	3.433949e-4
GO:0006397	mRNA processing	3.549784e-4
GO:0031536	positive regulation of exit from mitosis	3.785698e-4
GO:0045995	regulation of embryonic development	3.923405e-4
GO:0043628	ncRNA 3'-end processing	4.074024e-4
GO:0003348	cardiac endothelial cell differentiation	4.074024e-4
GO:0009225	nucleotide-sugar metabolic process	4.222608e-4
GO:0008380	RNA splicing	4.658231e-4
GO:0060968	regulation of gene silencing	4.739948e-4
GO:0006396	RNA processing	4.754997e-4
GO:0044085	cellular component biogenesis	4.948816e-4
GO:0072108	positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	5.022488e-4
GO:0034337	RNA folding	5.100718e-4
GO:0048251	elastic fiber assembly	5.288234e-4
GO:0070060	'de novo' actin filament nucleation	5.365542e-4
GO:0060214	endocardium formation	5.367354e-4
GO:0032236	positive regulation of calcium ion transport via store-operated calcium channel activity	5.677878e-4
GO:0000080	G1 phase of mitotic cell cycle	5.677878e-4
GO:0034622	cellular macromolecular complex assembly	5.714058e-4
GO:0001826	inner cell mass cell differentiation	6.101712e-4
GO:0034623	cellular macromolecular complex disassembly	6.249833e-4
GO:0044029	hypomethylation of CpG island	6.299939e-4
GO:0022900	electron transport chain	6.617668e-4
GO:2000833	positive regulation of steroid hormone secretion	6.897257e-4
GO:0051584	regulation of dopamine uptake	6.897257e-4
GO:0003308	negative regulation of Wnt receptor signaling pathway involved in heart development	6.897257e-4
GO:0034728	nucleosome organization	6.928923e-4
GO:0032984	macromolecular complex disassembly	7.172254e-4
GO:0035907	dorsal aorta development	7.318594e-4
GO:0002027	regulation of heart rate	7.449431e-4
GO:0006710	androgen catabolic process	7.833159e-4
GO:0019233	sensory perception of pain	7.840390e-4
GO:0085029	extracellular matrix assembly	8.192851e-4
GO:0046548	retinal rod cell development	8.209614e-4
GO:0048096	chromatin-mediated maintenance of transcription	8.209614e-4
GO:0030032	lamellipodium assembly	8.533629e-4
GO:2000831	regulation of steroid hormone secretion	8.679772e-4
GO:0061010	gall bladder development	8.679772e-4
GO:2000279	negative regulation of DNA biosynthetic process	8.722365e-4
GO:0007612	learning	8.963360e-4
GO:0042780	tRNA 3'-end processing	9.236001e-4
GO:0032235	negative regulation of calcium ion transport via store-operated calcium channel activity	9.236001e-4
GO:0034314	Arp2/3 complex-mediated actin nucleation	9.236001e-4
GO:0051254	positive regulation of RNA metabolic process	9.689221e-4
GO:0090322	regulation of superoxide metabolic process	9.852933e-4
GO:0007493	endodermal cell fate determination	1.019163e-3
GO:0035810	positive regulation of urine volume	1.073014e-3
GO:0007096	regulation of exit from mitosis	1.073014e-3
GO:0070358	actin polymerization-dependent cell motility	1.075047e-3
GO:0033688	regulation of osteoblast proliferation	1.076571e-3
GO:0003339	regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	1.128629e-3
GO:0050685	positive regulation of mRNA processing	1.140617e-3
GO:0072107	positive regulation of ureteric bud formation	1.186031e-3
GO:0006337	nucleosome disassembly	1.186031e-3
GO:0061009	common bile duct development	1.186031e-3
GO:0045585	positive regulation of cytotoxic T cell differentiation	1.237577e-3
GO:0008016	regulation of heart contraction	1.243920e-3
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	1.245242e-3
GO:0051045	negative regulation of membrane protein ectodomain proteolysis	1.276634e-3
GO:0022618	ribonucleoprotein complex assembly	1.285291e-3
GO:0010677	negative regulation of cellular carbohydrate metabolic process	1.287829e-3
GO:0003093	regulation of glomerular filtration	1.306281e-3
GO:0042661	regulation of mesodermal cell fate specification	1.306281e-3
GO:0048743	positive regulation of skeletal muscle fiber development	1.385805e-3
GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator	1.462101e-3
GO:0043567	regulation of insulin-like growth factor receptor signaling pathway	1.499400e-3
GO:0007346	regulation of mitotic cell cycle	1.499921e-3
GO:0008054	cyclin catabolic process	1.500586e-3
GO:0006744	ubiquinone biosynthetic process	1.500586e-3
GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway	1.541275e-3
GO:0071826	ribonucleoprotein complex subunit organization	1.629355e-3
GO:0030910	olfactory placode formation	1.639647e-3
GO:0006040	amino sugar metabolic process	1.643978e-3
GO:0001711	endodermal cell fate commitment	1.665555e-3
GO:0009451	RNA modification	1.792431e-3
GO:0043269	regulation of ion transport	1.935656e-3
GO:0051318	G1 phase	1.982281e-3
GO:0046549	retinal cone cell development	2.104261e-3
GO:0045426	quinone cofactor biosynthetic process	2.104261e-3
GO:0001977	renal system process involved in regulation of blood volume	2.104261e-3
GO:0006333	chromatin assembly or disassembly	2.163143e-3
GO:0051173	positive regulation of nitrogen compound metabolic process	2.202035e-3
GO:0034755	iron ion transmembrane transport	2.275439e-3
GO:0009996	negative regulation of cell fate specification	2.275439e-3
GO:0035082	axoneme assembly	2.364166e-3
GO:0034766	negative regulation of ion transmembrane transport	2.441125e-3
GO:0045719	negative regulation of glycogen biosynthetic process	2.455008e-3
GO:0032274	gonadotropin secretion	2.503616e-3
GO:0034349	glial cell apoptosis	2.547982e-3
GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway	2.560433e-3
GO:0060795	cell fate commitment involved in formation of primary germ layers	2.565759e-3
GO:0043154	negative regulation of caspase activity	2.654474e-3
GO:0071347	cellular response to interleukin-1	2.778739e-3
GO:0051580	regulation of neurotransmitter uptake	3.045402e-3
GO:0010454	negative regulation of cell fate commitment	3.151508e-3
GO:0051898	negative regulation of protein kinase B signaling cascade	3.178012e-3
GO:0090288	negative regulation of cellular response to growth factor stimulus	3.178012e-3
GO:0070874	negative regulation of glycogen metabolic process	3.259856e-3
GO:0009416	response to light stimulus	3.288381e-3
GO:0003014	renal system process	3.325964e-3
GO:0042375	quinone cofactor metabolic process	3.370463e-3
GO:2000278	regulation of DNA biosynthetic process	3.451127e-3
GO:0045746	negative regulation of Notch signaling pathway	3.451127e-3
GO:0035987	endodermal cell differentiation	3.451127e-3
GO:0070932	histone H3 deacetylation	3.455330e-3
GO:2000380	regulation of mesoderm development	3.483342e-3
GO:2001021	negative regulation of response to DNA damage stimulus	3.521816e-3
GO:0070555	response to interleukin-1	3.538137e-3
GO:0035809	regulation of urine volume	3.598508e-3
GO:0045935	positive regulation of nucleobase-containing compound metabolic process	3.602826e-3
GO:0044030	regulation of DNA methylation	3.666131e-3
GO:0031128	developmental induction	3.827553e-3
GO:0016202	regulation of striated muscle tissue development	3.904150e-3
GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling	4.082323e-3
GO:0060676	ureteric bud formation	4.082323e-3
GO:0001522	pseudouridine synthesis	4.082323e-3
GO:0070588	calcium ion transmembrane transport	4.123126e-3
GO:0048634	regulation of muscle organ development	4.178526e-3
GO:0071899	negative regulation of estrogen receptor binding	4.469869e-3
GO:0003160	endocardium morphogenesis	4.469869e-3
GO:0034616	response to laminar fluid shear stress	4.789989e-3
GO:0051179	localization	5.097938e-3
GO:0043933	macromolecular complex subunit organization	5.107939e-3
GO:0045168	cell-cell signaling involved in cell fate commitment	5.158614e-3
GO:0030432	peristalsis	5.163821e-3
GO:0031647	regulation of protein stability	5.265624e-3
GO:0060911	cardiac cell fate commitment	5.309925e-3
GO:0035305	negative regulation of dephosphorylation	5.309925e-3
GO:2001020	regulation of response to DNA damage stimulus	5.384705e-3
GO:0050680	negative regulation of epithelial cell proliferation	5.497882e-3
GO:0043161	proteasomal ubiquitin-dependent protein catabolic process	5.563143e-3
GO:0030162	regulation of proteolysis	5.728095e-3
GO:0071842	cellular component organization at cellular level	5.837850e-3
GO:0045815	positive regulation of gene expression, epigenetic	5.919102e-3
GO:0010498	proteasomal protein catabolic process	5.953129e-3
GO:0034619	cellular chaperone-mediated protein complex assembly	5.970507e-3
GO:0034983	peptidyl-lysine deacetylation	5.970507e-3
GO:0007626	locomotory behavior	6.013996e-3
GO:0032715	negative regulation of interleukin-6 production	6.021982e-3
GO:0071383	cellular response to steroid hormone stimulus	6.236038e-3
GO:0032414	positive regulation of ion transmembrane transporter activity	6.333459e-3
GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development	6.402280e-3
GO:0007059	chromosome segregation	6.491241e-3
GO:0045893	positive regulation of transcription, DNA-dependent	6.528329e-3
GO:0008633	activation of pro-apoptotic gene products	6.568401e-3
GO:0040019	positive regulation of embryonic development	6.655446e-3
GO:0080135	regulation of cellular response to stress	6.777285e-3
GO:0007431	salivary gland development	6.936209e-3
GO:0040030	regulation of molecular function, epigenetic	7.074992e-3
GO:0007216	metabotropic glutamate receptor signaling pathway	7.074992e-3
GO:0060986	endocrine hormone secretion	7.101362e-3
GO:0042074	cell migration involved in gastrulation	7.258458e-3
GO:0016070	RNA metabolic process	7.329214e-3
GO:0050658	RNA transport	7.432242e-3
GO:0032225	regulation of synaptic transmission, dopaminergic	7.437410e-3
GO:0016554	cytidine to uridine editing	7.462133e-3
GO:0051043	regulation of membrane protein ectodomain proteolysis	7.566561e-3
GO:0048641	regulation of skeletal muscle tissue development	7.582047e-3
GO:0003071	renal system process involved in regulation of systemic arterial blood pressure	7.618955e-3
GO:0043516	regulation of DNA damage response, signal transduction by p53 class mediator	7.685914e-3
GO:0060219	camera-type eye photoreceptor cell differentiation	8.179230e-3
GO:0045820	negative regulation of glycolysis	8.264459e-3
GO:0000381	regulation of alternative nuclear mRNA splicing, via spliceosome	8.301243e-3
GO:0007179	transforming growth factor beta receptor signaling pathway	8.319049e-3
GO:0043393	regulation of protein binding	8.376992e-3
GO:0034394	protein localization at cell surface	8.556134e-3
GO:0015931	nucleobase-containing compound transport	8.646648e-3
GO:0030031	cell projection assembly	8.801070e-3
GO:0051353	positive regulation of oxidoreductase activity	9.081145e-3
GO:0051131	chaperone-mediated protein complex assembly	9.103716e-3
GO:0045040	protein import into mitochondrial outer membrane	9.103716e-3
GO:0009048	dosage compensation, by inactivation of X chromosome	9.103716e-3
GO:0042176	regulation of protein catabolic process	9.140033e-3
GO:0007007	inner mitochondrial membrane organization	9.370866e-3
GO:0010628	positive regulation of gene expression	9.516508e-3
GO:0048484	enteric nervous system development	9.578773e-3
GO:0003337	mesenchymal to epithelial transition involved in metanephros morphogenesis	9.789355e-3
GO:0006403	RNA localization	1.012543e-2
GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	1.036541e-2
GO:0014894	response to denervation involved in regulation of muscle adaptation	1.043064e-2
GO:0060011	Sertoli cell proliferation	1.043064e-2
GO:0060664	epithelial cell proliferation involved in salivary gland morphogenesis	1.043722e-2
GO:0045603	positive regulation of endothelial cell differentiation	1.043722e-2
GO:0046209	nitric oxide metabolic process	1.065857e-2
GO:0031123	RNA 3'-end processing	1.075931e-2
GO:0034762	regulation of transmembrane transport	1.078623e-2
GO:0016553	base conversion or substitution editing	1.135983e-2
GO:0032411	positive regulation of transporter activity	1.138974e-2
GO:2000116	regulation of cysteine-type endopeptidase activity	1.162677e-2
GO:0006927	transformed cell apoptosis	1.183759e-2
GO:0002070	epithelial cell maturation	1.252722e-2
GO:0006091	generation of precursor metabolites and energy	1.259332e-2
GO:0045010	actin nucleation	1.281912e-2
GO:0006511	ubiquitin-dependent protein catabolic process	1.299660e-2
GO:0071841	cellular component organization or biogenesis at cellular level	1.309468e-2
GO:0045732	positive regulation of protein catabolic process	1.373301e-2
GO:0018191	peptidyl-serine octanoylation	1.388511e-2
GO:0031328	positive regulation of cellular biosynthetic process	1.416939e-2
GO:0003157	endocardium development	1.430637e-2
GO:0019941	modification-dependent protein catabolic process	1.441435e-2
GO:0043632	modification-dependent macromolecule catabolic process	1.471182e-2
GO:0046883	regulation of hormone secretion	1.481854e-2
GO:0007006	mitochondrial membrane organization	1.483906e-2
GO:0033137	negative regulation of peptidyl-serine phosphorylation	1.483961e-2
GO:0016584	nucleosome positioning	1.488437e-2
GO:0048870	cell motility	1.513942e-2
GO:0043401	steroid hormone mediated signaling pathway	1.530187e-2
GO:0010832	negative regulation of myotube differentiation	1.596704e-2
GO:0010216	maintenance of DNA methylation	1.596704e-2
GO:0070301	cellular response to hydrogen peroxide	1.609043e-2
GO:0072283	metanephric renal vesicle morphogenesis	1.622140e-2
GO:0071456	cellular response to hypoxia	1.645125e-2
GO:0043271	negative regulation of ion transport	1.645125e-2
GO:0030858	positive regulation of epithelial cell differentiation	1.646941e-2
GO:0003347	epicardial cell to mesenchymal cell transition	1.652067e-2
GO:0071356	cellular response to tumor necrosis factor	1.660334e-2
GO:0051258	protein polymerization	1.671615e-2
GO:0034614	cellular response to reactive oxygen species	1.673415e-2
GO:0032770	positive regulation of monooxygenase activity	1.679365e-2
GO:0048821	erythrocyte development	1.686409e-2
GO:0030433	ER-associated protein catabolic process	1.706363e-2
GO:0071824	protein-DNA complex subunit organization	1.706426e-2
GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan	1.708397e-2
GO:0048617	embryonic foregut morphogenesis	1.708397e-2
GO:0060850	regulation of transcription involved in cell fate commitment	1.737709e-2
GO:0070933	histone H4 deacetylation	1.765218e-2
GO:0010838	positive regulation of keratinocyte proliferation	1.765218e-2
GO:0033235	positive regulation of protein sumoylation	1.765218e-2
GO:0010466	negative regulation of peptidase activity	1.789718e-2
GO:0009891	positive regulation of biosynthetic process	1.795948e-2
GO:0001759	organ induction	1.797174e-2
GO:0044060	regulation of endocrine process	1.797174e-2
GO:0007435	salivary gland morphogenesis	1.801434e-2
GO:0048024	regulation of nuclear mRNA splicing, via spliceosome	1.808345e-2
GO:0014821	phasic smooth muscle contraction	1.827327e-2
GO:0090304	nucleic acid metabolic process	1.832154e-2
GO:0008285	negative regulation of cell proliferation	1.856219e-2
GO:0014874	response to stimulus involved in regulation of muscle adaptation	1.881561e-2
GO:0006548	histidine catabolic process	1.881561e-2
GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway	1.883140e-2
GO:0072077	renal vesicle morphogenesis	1.919471e-2
GO:0042220	response to cocaine	1.935625e-2
GO:0032463	negative regulation of protein homooligomerization	1.940915e-2
GO:0000819	sister chromatid segregation	1.979250e-2
GO:0051726	regulation of cell cycle	1.998125e-2
GO:0009108	coenzyme biosynthetic process	2.009709e-2
GO:0090287	regulation of cellular response to growth factor stimulus	2.053781e-2
GO:0006547	histidine metabolic process	2.061955e-2
GO:0031330	negative regulation of cellular catabolic process	2.067804e-2
GO:0009438	methylglyoxal metabolic process	2.075537e-2
GO:0060768	regulation of epithelial cell proliferation involved in prostate gland development	2.078666e-2
GO:0071345	cellular response to cytokine stimulus	2.092729e-2
GO:0051155	positive regulation of striated muscle cell differentiation	2.160857e-2
GO:0034504	protein localization to nucleus	2.188538e-2
GO:0045601	regulation of endothelial cell differentiation	2.211087e-2
GO:0071453	cellular response to oxygen levels	2.234222e-2
GO:0032844	regulation of homeostatic process	2.247646e-2
GO:0006816	calcium ion transport	2.290445e-2
GO:0008593	regulation of Notch signaling pathway	2.309183e-2
GO:0031000	response to caffeine	2.325770e-2
GO:0010557	positive regulation of macromolecule biosynthetic process	2.339729e-2
GO:0030856	regulation of epithelial cell differentiation	2.339996e-2
GO:0008033	tRNA processing	2.343321e-2
GO:0006826	iron ion transport	2.374575e-2
GO:0001706	endoderm formation	2.399209e-2
GO:0010826	negative regulation of centrosome duplication	2.417258e-2
GO:0072091	regulation of stem cell proliferation	2.418160e-2
GO:0031060	regulation of histone methylation	2.453656e-2
GO:0010604	positive regulation of macromolecule metabolic process	2.487030e-2
GO:0051603	proteolysis involved in cellular protein catabolic process	2.530074e-2
GO:0030574	collagen catabolic process	2.598454e-2
GO:0042659	regulation of cell fate specification	2.598454e-2
GO:0001941	postsynaptic membrane organization	2.598454e-2
GO:0032237	activation of store-operated calcium channel activity	2.643925e-2
GO:0001656	metanephros development	2.645154e-2
GO:0032781	positive regulation of ATPase activity	2.672537e-2
GO:0016572	histone phosphorylation	2.672537e-2
GO:0060235	lens induction in camera-type eye	2.709999e-2
GO:0007440	foregut morphogenesis	2.709999e-2
GO:0045214	sarcomere organization	2.712210e-2
GO:0045078	positive regulation of interferon-gamma biosynthetic process	2.712236e-2
GO:0043010	camera-type eye development	2.747650e-2
GO:0046716	muscle cell homeostasis	2.785765e-2
GO:0050796	regulation of insulin secretion	2.828357e-2
GO:0033233	regulation of protein sumoylation	2.850977e-2
GO:0006349	regulation of gene expression by genetic imprinting	2.862650e-2
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	2.884041e-2
GO:0043491	protein kinase B signaling cascade	2.901513e-2
GO:0031325	positive regulation of cellular metabolic process	2.925351e-2
GO:0072087	renal vesicle development	2.940654e-2
GO:0060231	mesenchymal to epithelial transition	2.940654e-2
GO:2000465	regulation of glycogen (starch) synthase activity	2.980075e-2
GO:0030838	positive regulation of actin filament polymerization	2.980549e-2
GO:0006139	nucleobase-containing compound metabolic process	2.984169e-2
GO:0043620	regulation of DNA-dependent transcription in response to stress	3.019774e-2
GO:0010171	body morphogenesis	3.019870e-2
GO:0060562	epithelial tube morphogenesis	3.030616e-2
GO:0051928	positive regulation of calcium ion transport	3.034783e-2
GO:0034405	response to fluid shear stress	3.037165e-2
GO:0043270	positive regulation of ion transport	3.041163e-2
GO:0044257	cellular protein catabolic process	3.041493e-2
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	3.059753e-2
GO:0065003	macromolecular complex assembly	3.112375e-2
GO:0060037	pharyngeal system development	3.140545e-2
GO:0014074	response to purine-containing compound	3.210810e-2
GO:0048486	parasympathetic nervous system development	3.222448e-2
GO:0009314	response to radiation	3.243510e-2
GO:0006906	vesicle fusion	3.263816e-2
GO:0032963	collagen metabolic process	3.265593e-2
GO:0045494	photoreceptor cell maintenance	3.347384e-2
GO:0052547	regulation of peptidase activity	3.355388e-2
GO:0006809	nitric oxide biosynthetic process	3.358219e-2
GO:0055072	iron ion homeostasis	3.384991e-2
GO:0021903	rostrocaudal neural tube patterning	3.389582e-2
GO:0048561	establishment of organ orientation	3.435299e-2
GO:0007611	learning or memory	3.464006e-2
GO:0035239	tube morphogenesis	3.469727e-2
GO:0009755	hormone-mediated signaling pathway	3.469934e-2
GO:0051234	establishment of localization	3.475236e-2
GO:0042026	protein refolding	3.509146e-2
GO:0006917	induction of apoptosis	3.557024e-2
GO:0072088	nephron epithelium morphogenesis	3.575241e-2
GO:0001578	microtubule bundle formation	3.575241e-2
GO:0090073	positive regulation of protein homodimerization activity	3.585582e-2
GO:0042267	natural killer cell mediated cytotoxicity	3.585582e-2
GO:0055114	oxidation-reduction process	3.638355e-2
GO:0051225	spindle assembly	3.648563e-2
GO:0043584	nose development	3.648563e-2
GO:0061037	negative regulation of cartilage development	3.662660e-2
GO:0071478	cellular response to radiation	3.682497e-2
GO:0012502	induction of programmed cell death	3.685305e-2
GO:0045930	negative regulation of mitotic cell cycle	3.701813e-2
GO:0048255	mRNA stabilization	3.737087e-2
GO:0007549	dosage compensation	3.740373e-2
GO:0001824	blastocyst development	3.796733e-2
GO:0009790	embryo development	3.802486e-2
GO:0044259	multicellular organismal macromolecule metabolic process	3.811048e-2
GO:0045072	regulation of interferon-gamma biosynthetic process	3.818716e-2
GO:0030030	cell projection organization	3.826468e-2
GO:0031497	chromatin assembly	3.840683e-2
GO:0034599	cellular response to oxidative stress	3.888856e-2
GO:0023019	signal transduction involved in regulation of gene expression	3.917413e-2
GO:0010453	regulation of cell fate commitment	3.917413e-2
GO:0010467	gene expression	3.935488e-2
GO:0006399	tRNA metabolic process	4.017009e-2
GO:0045786	negative regulation of cell cycle	4.047349e-2
GO:0019221	cytokine-mediated signaling pathway	4.065501e-2
GO:0042512	negative regulation of tyrosine phosphorylation of Stat1 protein	4.108100e-2
GO:0002071	glandular epithelial cell maturation	4.108100e-2
GO:0051341	regulation of oxidoreductase activity	4.164924e-2
GO:0035162	embryonic hemopoiesis	4.268234e-2
GO:0048742	regulation of skeletal muscle fiber development	4.274407e-2
GO:0000902	cell morphogenesis	4.297892e-2
GO:0042127	regulation of cell proliferation	4.298097e-2
GO:0043467	regulation of generation of precursor metabolites and energy	4.321777e-2
GO:0030204	chondroitin sulfate metabolic process	4.339007e-2
GO:0070683	mitotic cell cycle G2/M transition decatenation checkpoint	4.442745e-2
GO:0060133	somatotropin secreting cell development	4.442745e-2
GO:0006421	asparaginyl-tRNA aminoacylation	4.442745e-2
GO:0006928	cellular component movement	4.483666e-2
GO:0090276	regulation of peptide hormone secretion	4.497786e-2
GO:0001947	heart looping	4.523465e-2
GO:0051154	negative regulation of striated muscle cell differentiation	4.720605e-2
GO:0006733	oxidoreduction coenzyme metabolic process	4.727945e-2
GO:0001654	eye development	4.737663e-2
GO:0050684	regulation of mRNA processing	4.769327e-2
GO:0016191	synaptic vesicle uncoating	4.776225e-2
GO:0006110	regulation of glycolysis	4.782292e-2
GO:0044057	regulation of system process	4.819186e-2
GO:0072215	regulation of metanephros development	4.832870e-2
GO:0035335	peptidyl-tyrosine dephosphorylation	4.837997e-2
GO:0009893	positive regulation of metabolic process	4.889687e-2
GO:0061303	cornea development in camera-type eye	4.892173e-2
GO:0072028	nephron morphogenesis	4.918228e-2
GO:0030163	protein catabolic process	5.007006e-2
GO:0034097	response to cytokine stimulus	5.054878e-2
GO:0045668	negative regulation of osteoblast differentiation	5.107927e-2
GO:0071206	establishment of protein localization to juxtaparanode region of axon	5.108544e-2
GO:0060168	positive regulation of adenosine receptor signaling pathway	5.108544e-2
GO:0019452	L-cysteine catabolic process to taurine	5.108544e-2
GO:0032413	negative regulation of ion transmembrane transporter activity	5.153702e-2
GO:0048754	branching morphogenesis of a tube	5.223900e-2
GO:0060042	retina morphogenesis in camera-type eye	5.262538e-2
GO:0002791	regulation of peptide secretion	5.311018e-2
GO:0072210	metanephric nephron development	5.340792e-2
GO:0043623	cellular protein complex assembly	5.381364e-2
GO:0071156	regulation of cell cycle arrest	5.386984e-2
GO:0048305	immunoglobulin secretion	5.420127e-2
GO:0032269	negative regulation of cellular protein metabolic process	5.425906e-2
GO:0072272	proximal/distal pattern formation involved in metanephric nephron development	5.439706e-2
GO:0034699	response to luteinizing hormone stimulus	5.439706e-2
GO:0010157	response to chlorate	5.439706e-2
GO:0050890	cognition	5.494129e-2
GO:0090090	negative regulation of canonical Wnt receptor signaling pathway	5.585850e-2
GO:0051346	negative regulation of hydrolase activity	5.678934e-2
GO:0030522	intracellular receptor mediated signaling pathway	5.696385e-2
GO:0034612	response to tumor necrosis factor	5.731587e-2
GO:0070349	positive regulation of brown fat cell proliferation	5.769715e-2
GO:0000461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	5.769715e-2
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	5.769715e-2
GO:0043624	cellular protein complex disassembly	5.782749e-2
GO:0001708	cell fate specification	5.782804e-2
GO:0060442	branching involved in prostate gland morphogenesis	5.787641e-2
GO:0030866	cortical actin cytoskeleton organization	5.787641e-2
GO:0035272	exocrine system development	5.839833e-2
GO:0021532	neural tube patterning	5.864791e-2
GO:0043488	regulation of mRNA stability	5.906196e-2
GO:0001658	branching involved in ureteric bud morphogenesis	5.932363e-2
GO:0071845	cellular component disassembly at cellular level	5.966212e-2
GO:0006839	mitochondrial transport	5.966212e-2
GO:0033205	cell cycle cytokinesis	5.967142e-2
GO:0044260	cellular macromolecule metabolic process	5.995827e-2
GO:0016043	cellular component organization	6.109097e-2
GO:0060044	negative regulation of cardiac muscle cell proliferation	6.153541e-2
GO:0022411	cellular component disassembly	6.171620e-2
GO:0006405	RNA export from nucleus	6.181195e-2
GO:0018208	peptidyl-proline modification	6.200397e-2
GO:0034641	cellular nitrogen compound metabolic process	6.215891e-2
GO:0051153	regulation of striated muscle cell differentiation	6.225859e-2
GO:0001667	ameboidal cell migration	6.225859e-2
GO:0019432	triglyceride biosynthetic process	6.247480e-2
GO:0045765	regulation of angiogenesis	6.279871e-2
GO:0048013	ephrin receptor signaling pathway	6.285853e-2
GO:0043241	protein complex disassembly	6.341907e-2
GO:0007041	lysosomal transport	6.411543e-2
GO:0043487	regulation of RNA stability	6.415197e-2
GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process	6.416271e-2