Novel motif:155

name:	motif155_AATARSTCCC

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0021858	GABAergic neuron differentiation in basal ganglia	1.496876e-14
GO:0045901	positive regulation of translational elongation	6.703905e-11
GO:0045905	positive regulation of translational termination	6.703905e-11
GO:0006452	translational frameshifting	6.703905e-11
GO:0034201	response to oleic acid	1.023200e-10
GO:0008612	peptidyl-lysine modification to hypusine	2.789528e-10
GO:0033211	adiponectin-mediated signaling pathway	4.477527e-9
GO:2000514	regulation of CD4-positive, alpha-beta T cell activation	5.589139e-9
GO:0018283	iron incorporation into metallo-sulfur cluster	6.882703e-9
GO:0043370	regulation of CD4-positive, alpha-beta T cell differentiation	1.545761e-8
GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	2.620771e-8
GO:0045622	regulation of T-helper cell differentiation	7.176473e-8
GO:0045624	positive regulation of T-helper cell differentiation	7.753904e-8
GO:0001967	suckling behavior	1.000352e-7
GO:0042572	retinol metabolic process	1.089643e-7
GO:0043244	regulation of protein complex disassembly	1.428875e-7
GO:0071338	positive regulation of hair follicle cell proliferation	2.033794e-7
GO:0042178	xenobiotic catabolic process	2.408365e-7
GO:0046635	positive regulation of alpha-beta T cell activation	3.208215e-7
GO:2000602	regulation of interphase of mitotic cell cycle	3.281518e-7
GO:0010259	multicellular organismal aging	3.283774e-7
GO:0043200	response to amino acid stimulus	3.529310e-7
GO:0032535	regulation of cellular component size	4.622085e-7
GO:0071312	cellular response to alkaloid	5.376967e-7
GO:0019230	proprioception	6.975884e-7
GO:0003009	skeletal muscle contraction	7.306443e-7
GO:0006448	regulation of translational elongation	8.057248e-7
GO:0016226	iron-sulfur cluster assembly	8.817397e-7
GO:0046637	regulation of alpha-beta T cell differentiation	1.105356e-6
GO:0030837	negative regulation of actin filament polymerization	1.146929e-6
GO:0043243	positive regulation of protein complex disassembly	1.191634e-6
GO:0046634	regulation of alpha-beta T cell activation	1.214575e-6
GO:0045606	positive regulation of epidermal cell differentiation	1.249316e-6
GO:0070302	regulation of stress-activated protein kinase signaling cascade	1.345680e-6
GO:0033574	response to testosterone stimulus	1.398578e-6
GO:0014075	response to amine stimulus	1.549989e-6
GO:2000119	negative regulation of sodium-dependent phosphate transport	1.600534e-6
GO:0006436	tryptophanyl-tRNA aminoacylation	1.686975e-6
GO:0032007	negative regulation of TOR signaling cascade	1.829371e-6
GO:0051608	histamine transport	1.905066e-6
GO:0003334	keratinocyte development	1.916760e-6
GO:0031023	microtubule organizing center organization	2.108448e-6
GO:0045627	positive regulation of T-helper 1 cell differentiation	2.312822e-6
GO:0046092	deoxycytidine metabolic process	2.482796e-6
GO:0042509	regulation of tyrosine phosphorylation of STAT protein	2.643663e-6
GO:0001101	response to acid	2.736083e-6
GO:0021544	subpallium development	2.757399e-6
GO:0006904	vesicle docking involved in exocytosis	2.832396e-6
GO:0042989	sequestering of actin monomers	2.934023e-6
GO:0006449	regulation of translational termination	3.168667e-6
GO:0048638	regulation of developmental growth	3.386287e-6
GO:0008361	regulation of cell size	3.649374e-6
GO:0046638	positive regulation of alpha-beta T cell differentiation	3.652055e-6
GO:0080134	regulation of response to stress	3.814225e-6
GO:0045684	positive regulation of epidermis development	3.818680e-6
GO:0048210	Golgi vesicle fusion to target membrane	4.085334e-6
GO:0010509	polyamine homeostasis	4.577032e-6
GO:0007098	centrosome cycle	4.846399e-6
GO:0034109	homotypic cell-cell adhesion	5.447100e-6
GO:0051494	negative regulation of cytoskeleton organization	6.037364e-6
GO:0002090	regulation of receptor internalization	6.722283e-6
GO:0043374	CD8-positive, alpha-beta T cell differentiation	6.873737e-6
GO:0044068	modulation by symbiont of host cellular process	7.051580e-6
GO:0014821	phasic smooth muscle contraction	7.274284e-6
GO:0042512	negative regulation of tyrosine phosphorylation of Stat1 protein	7.417197e-6
GO:0001780	neutrophil homeostasis	7.546208e-6
GO:0006776	vitamin A metabolic process	8.482115e-6
GO:0006463	steroid hormone receptor complex assembly	8.953808e-6
GO:0002091	negative regulation of receptor internalization	9.425126e-6
GO:0021612	facial nerve structural organization	9.464499e-6
GO:0043060	meiotic metaphase I plate congression	9.661266e-6
GO:0031349	positive regulation of defense response	9.899038e-6
GO:0009052	pentose-phosphate shunt, non-oxidative branch	1.002047e-5
GO:0001821	histamine secretion	1.047252e-5
GO:0070527	platelet aggregation	1.142608e-5
GO:0019054	modulation by virus of host cellular process	1.225181e-5
GO:0045582	positive regulation of T cell differentiation	1.371875e-5
GO:0060039	pericardium development	1.378794e-5
GO:0010172	embryonic body morphogenesis	1.402409e-5
GO:0045726	positive regulation of integrin biosynthetic process	1.555046e-5
GO:0010243	response to organic nitrogen	1.755001e-5
GO:0071277	cellular response to calcium ion	1.847168e-5
GO:0051297	centrosome organization	1.854357e-5
GO:0060154	cellular process regulating host cell cycle in response to virus	1.923003e-5
GO:0070304	positive regulation of stress-activated protein kinase signaling cascade	1.958604e-5
GO:0032272	negative regulation of protein polymerization	1.971988e-5
GO:0006936	muscle contraction	1.987576e-5
GO:0060591	chondroblast differentiation	2.208417e-5
GO:0042891	antibiotic transport	2.229167e-5
GO:0051988	regulation of attachment of spindle microtubules to kinetochore	2.229167e-5
GO:0045621	positive regulation of lymphocyte differentiation	2.354274e-5
GO:0019693	ribose phosphate metabolic process	2.374240e-5
GO:0003416	endochondral bone growth	2.374240e-5
GO:0002032	desensitization of G-protein coupled receptor protein signaling pathway by arrestin	2.555771e-5
GO:0021610	facial nerve morphogenesis	2.562055e-5
GO:0097037	heme export	2.617582e-5
GO:0002825	regulation of T-helper 1 type immune response	2.709644e-5
GO:0060520	activation of prostate induction by androgen receptor signaling pathway	2.764741e-5
GO:0045720	negative regulation of integrin biosynthetic process	2.764741e-5
GO:0019102	male somatic sex determination	2.764741e-5
GO:0045792	negative regulation of cell size	2.914170e-5
GO:0018205	peptidyl-lysine modification	2.930378e-5
GO:0046329	negative regulation of JNK cascade	2.931037e-5
GO:0021756	striatum development	2.951250e-5
GO:0032902	nerve growth factor production	3.256833e-5
GO:0046425	regulation of JAK-STAT cascade	3.261711e-5
GO:0045823	positive regulation of heart contraction	3.266671e-5
GO:0006740	NADPH regeneration	3.385235e-5
GO:0006991	response to sterol depletion	3.435263e-5
GO:0046328	regulation of JNK cascade	3.484599e-5
GO:0051901	positive regulation of mitochondrial depolarization	3.516795e-5
GO:0071731	response to nitric oxide	3.538441e-5
GO:0048278	vesicle docking	3.548180e-5
GO:0061090	positive regulation of sequestering of zinc ion	3.607540e-5
GO:0090201	negative regulation of release of cytochrome c from mitochondria	3.758344e-5
GO:0035264	multicellular organism growth	3.862745e-5
GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein	3.915192e-5
GO:0006693	prostaglandin metabolic process	4.153978e-5
GO:0016197	endosome transport	4.412777e-5
GO:0015886	heme transport	5.064061e-5
GO:0042108	positive regulation of cytokine biosynthetic process	5.143526e-5
GO:0070542	response to fatty acid	5.234803e-5
GO:0016101	diterpenoid metabolic process	5.283155e-5
GO:0071044	histone mRNA catabolic process	5.511681e-5
GO:0030252	growth hormone secretion	5.733777e-5
GO:0032455	nerve growth factor processing	6.043804e-5
GO:0021561	facial nerve development	6.132807e-5
GO:0032819	positive regulation of natural killer cell proliferation	6.692911e-5
GO:0051094	positive regulation of developmental process	6.705080e-5
GO:0031670	cellular response to nutrient	6.899356e-5
GO:0021570	rhombomere 4 development	6.907189e-5
GO:0002532	production of molecular mediator involved in inflammatory response	7.440308e-5
GO:0035115	embryonic forelimb morphogenesis	7.511948e-5
GO:0060164	regulation of timing of neuron differentiation	7.527801e-5
GO:0048639	positive regulation of developmental growth	7.555839e-5
GO:0090005	negative regulation of establishment of protein localization in plasma membrane	7.983301e-5
GO:0031619	homologous chromosome orientation involved in meiotic metaphase I plate congression	8.292056e-5
GO:0003012	muscle system process	8.540894e-5
GO:0045014	negative regulation of transcription by glucose	8.613674e-5
GO:0031333	negative regulation of protein complex assembly	8.914250e-5
GO:0008284	positive regulation of cell proliferation	9.009910e-5
GO:0010045	response to nickel ion	9.110309e-5
GO:0045595	regulation of cell differentiation	9.311441e-5
GO:0046415	urate metabolic process	9.717472e-5
GO:0003417	growth plate cartilage development	9.717872e-5
GO:0032649	regulation of interferon-gamma production	9.756192e-5
GO:0035136	forelimb morphogenesis	1.021709e-4
GO:0046631	alpha-beta T cell activation	1.038882e-4
GO:0006777	Mo-molybdopterin cofactor biosynthetic process	1.098872e-4
GO:0035051	cardiac cell differentiation	1.135280e-4
GO:0042938	dipeptide transport	1.159589e-4
GO:0080135	regulation of cellular response to stress	1.171838e-4
GO:0009968	negative regulation of signal transduction	1.187365e-4
GO:0016557	peroxisome membrane biogenesis	1.224678e-4
GO:0070741	response to interleukin-6	1.256851e-4
GO:0060980	cell migration involved in coronary vasculogenesis	1.261217e-4
GO:0061037	negative regulation of cartilage development	1.270376e-4
GO:0051705	behavioral interaction between organisms	1.321108e-4
GO:0010741	negative regulation of intracellular protein kinase cascade	1.327879e-4
GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation	1.392705e-4
GO:0023057	negative regulation of signaling	1.398021e-4
GO:0055012	ventricular cardiac muscle cell differentiation	1.403592e-4
GO:0070078	histone H3-R2 demethylation	1.404375e-4
GO:0070079	histone H4-R3 demethylation	1.404375e-4
GO:0018395	peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine	1.404375e-4
GO:0043409	negative regulation of MAPKKK cascade	1.448910e-4
GO:0006206	pyrimidine base metabolic process	1.463593e-4
GO:0043486	histone exchange	1.489002e-4
GO:0045625	regulation of T-helper 1 cell differentiation	1.531924e-4
GO:0032817	regulation of natural killer cell proliferation	1.535862e-4
GO:2000045	regulation of G1/S transition of mitotic cell cycle	1.568353e-4
GO:0045113	regulation of integrin biosynthetic process	1.594934e-4
GO:0071425	hemopoietic stem cell proliferation	1.595318e-4
GO:0071295	cellular response to vitamin	1.602631e-4
GO:0030201	heparan sulfate proteoglycan metabolic process	1.603837e-4
GO:0031346	positive regulation of cell projection organization	1.631362e-4
GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin	1.640846e-4
GO:0071732	cellular response to nitric oxide	1.642629e-4
GO:0001993	regulation of systemic arterial blood pressure by norepinephrine-epinephrine	1.647954e-4
GO:0051983	regulation of chromosome segregation	1.724540e-4
GO:0046426	negative regulation of JAK-STAT cascade	1.758001e-4
GO:0048664	neuron fate determination	1.763122e-4
GO:0060297	regulation of sarcomere organization	1.778708e-4
GO:0044255	cellular lipid metabolic process	1.784962e-4
GO:0090003	regulation of establishment of protein localization in plasma membrane	1.799642e-4
GO:0045945	positive regulation of transcription from RNA polymerase III promoter	1.837288e-4
GO:0030514	negative regulation of BMP signaling pathway	1.841469e-4
GO:0010817	regulation of hormone levels	1.844667e-4
GO:0006692	prostanoid metabolic process	1.852891e-4
GO:0042095	interferon-gamma biosynthetic process	1.865276e-4
GO:0007585	respiratory gaseous exchange	1.885897e-4
GO:0046985	positive regulation of hemoglobin biosynthetic process	1.908914e-4
GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery	1.908914e-4
GO:0043973	histone H3-K4 acetylation	1.908914e-4
GO:0010823	negative regulation of mitochondrion organization	1.946999e-4
GO:0010722	regulation of ferrochelatase activity	1.979871e-4
GO:0007344	pronuclear fusion	1.979871e-4
GO:0003300	cardiac muscle hypertrophy	1.992702e-4
GO:0051313	attachment of spindle microtubules to chromosome	2.004159e-4
GO:0050881	musculoskeletal movement	2.021824e-4
GO:0045750	positive regulation of S phase of mitotic cell cycle	2.039819e-4
GO:0032812	positive regulation of epinephrine secretion	2.054333e-4
GO:0070253	somatostatin secretion	2.054333e-4
GO:0044091	membrane biogenesis	2.116394e-4
GO:0035583	negative regulation of transforming growth factor beta receptor signaling pathway by extracellular sequestering of TGFbeta	2.116394e-4
GO:0010648	negative regulation of cell communication	2.134765e-4
GO:0045580	regulation of T cell differentiation	2.148818e-4
GO:0015833	peptide transport	2.187542e-4
GO:0045088	regulation of innate immune response	2.271905e-4
GO:0051092	positive regulation of NF-kappaB transcription factor activity	2.295582e-4
GO:0046898	response to cycloheximide	2.305348e-4
GO:0048633	positive regulation of skeletal muscle tissue growth	2.309734e-4
GO:0043415	positive regulation of skeletal muscle tissue regeneration	2.309734e-4
GO:0045089	positive regulation of innate immune response	2.340609e-4
GO:0050974	detection of mechanical stimulus involved in sensory perception	2.403875e-4
GO:0050870	positive regulation of T cell activation	2.419821e-4
GO:0070673	response to interleukin-18	2.423129e-4
GO:0016264	gap junction assembly	2.447682e-4
GO:0045597	positive regulation of cell differentiation	2.507388e-4
GO:0019722	calcium-mediated signaling	2.518617e-4
GO:0032456	endocytic recycling	2.526277e-4
GO:0019321	pentose metabolic process	2.537141e-4
GO:0032006	regulation of TOR signaling cascade	2.642298e-4
GO:0070350	regulation of white fat cell proliferation	2.744888e-4
GO:0045619	regulation of lymphocyte differentiation	2.747839e-4
GO:0001961	positive regulation of cytokine-mediated signaling pathway	2.788390e-4
GO:0034391	regulation of smooth muscle cell apoptosis	2.796637e-4
GO:0090066	regulation of anatomical structure size	3.018871e-4
GO:0043044	ATP-dependent chromatin remodeling	3.097912e-4
GO:0043242	negative regulation of protein complex disassembly	3.113494e-4
GO:0006637	acyl-CoA metabolic process	3.134684e-4
GO:0007413	axonal fasciculation	3.210277e-4
GO:0060338	regulation of type I interferon-mediated signaling pathway	3.235177e-4
GO:0046330	positive regulation of JNK cascade	3.254353e-4
GO:0070303	negative regulation of stress-activated protein kinase signaling cascade	3.274045e-4
GO:0002218	activation of innate immune response	3.306556e-4
GO:0042325	regulation of phosphorylation	3.320218e-4
GO:0033559	unsaturated fatty acid metabolic process	3.353272e-4
GO:0002689	negative regulation of leukocyte chemotaxis	3.428398e-4
GO:0030510	regulation of BMP signaling pathway	3.432570e-4
GO:0010639	negative regulation of organelle organization	3.449035e-4
GO:0046394	carboxylic acid biosynthetic process	3.452800e-4
GO:0002025	vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure	3.737733e-4
GO:0031575	mitotic cell cycle G1/S transition checkpoint	3.755584e-4
GO:0022601	menstrual cycle phase	3.775519e-4
GO:0010976	positive regulation of neuron projection development	3.795930e-4
GO:0071241	cellular response to inorganic substance	3.842521e-4
GO:0045161	neuronal ion channel clustering	3.899917e-4
GO:0032532	regulation of microvillus length	3.953207e-4
GO:0070715	sodium-dependent organic cation transport	4.161003e-4
GO:0060731	positive regulation of intestinal epithelial structure maintenance	4.161003e-4
GO:0052106	quorum sensing involved in interaction with host	4.161003e-4
GO:0045162	clustering of voltage-gated sodium channels	4.162582e-4
GO:0002540	leukotriene production involved in inflammatory response	4.228772e-4
GO:0048663	neuron fate commitment	4.251017e-4
GO:0019221	cytokine-mediated signaling pathway	4.326706e-4
GO:0007204	elevation of cytosolic calcium ion concentration	4.377054e-4
GO:0003321	positive regulation of blood pressure by epinephrine-norepinephrine	4.426146e-4
GO:0051276	chromosome organization	4.449704e-4
GO:0008610	lipid biosynthetic process	4.459872e-4
GO:0021569	rhombomere 3 development	4.462609e-4
GO:0032880	regulation of protein localization	4.522159e-4
GO:0040036	regulation of fibroblast growth factor receptor signaling pathway	4.544446e-4
GO:0002729	positive regulation of natural killer cell cytokine production	4.554862e-4
GO:0055007	cardiac muscle cell differentiation	4.624062e-4
GO:0060760	positive regulation of response to cytokine stimulus	4.628386e-4
GO:0019220	regulation of phosphate metabolic process	4.673162e-4
GO:0032722	positive regulation of chemokine production	4.872267e-4
GO:0030516	regulation of axon extension	4.886655e-4
GO:0031532	actin cytoskeleton reorganization	4.894013e-4
GO:0071230	cellular response to amino acid stimulus	4.921334e-4
GO:0046632	alpha-beta T cell differentiation	4.957231e-4
GO:0021783	preganglionic parasympathetic nervous system development	5.011582e-4
GO:0003059	positive regulation of the force of heart contraction by epinephrine	5.011906e-4
GO:0019227	neuronal action potential propagation	5.048105e-4
GO:0030072	peptide hormone secretion	5.071030e-4
GO:0006685	sphingomyelin catabolic process	5.312050e-4
GO:0006014	D-ribose metabolic process	5.381096e-4
GO:0070507	regulation of microtubule cytoskeleton organization	5.382126e-4
GO:0009892	negative regulation of metabolic process	5.443125e-4
GO:0050801	ion homeostasis	5.527061e-4
GO:0032271	regulation of protein polymerization	5.630399e-4
GO:0045931	positive regulation of mitotic cell cycle	5.961687e-4
GO:0032530	regulation of microvillus organization	6.256312e-4
GO:0035441	cell migration involved in vasculogenesis	6.261006e-4
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	6.304529e-4
GO:2000021	regulation of ion homeostasis	6.364681e-4
GO:0001523	retinoid metabolic process	6.650986e-4
GO:0071229	cellular response to acid	6.704009e-4
GO:0006098	pentose-phosphate shunt	6.740185e-4
GO:0032680	regulation of tumor necrosis factor production	6.827889e-4
GO:0006775	fat-soluble vitamin metabolic process	6.897045e-4
GO:0006633	fatty acid biosynthetic process	6.897711e-4
GO:0031860	telomeric 3' overhang formation	6.968678e-4
GO:0001682	tRNA 5'-leader removal	6.968678e-4
GO:0016078	tRNA catabolic process	6.968678e-4
GO:0030431	sleep	7.007966e-4
GO:0070671	response to interleukin-12	7.017360e-4
GO:0033600	negative regulation of mammary gland epithelial cell proliferation	7.061043e-4
GO:0043201	response to leucine	7.200376e-4
GO:0051891	positive regulation of cardioblast differentiation	7.284243e-4
GO:0051303	establishment of chromosome localization	7.369956e-4
GO:0007090	regulation of S phase of mitotic cell cycle	7.435513e-4
GO:0048665	neuron fate specification	7.454234e-4
GO:0051338	regulation of transferase activity	7.459895e-4
GO:0042573	retinoic acid metabolic process	7.475063e-4
GO:0071779	G1/S transition checkpoint	7.523207e-4
GO:0060599	lateral sprouting involved in mammary gland duct morphogenesis	7.659253e-4
GO:0055082	cellular chemical homeostasis	7.737153e-4
GO:0002828	regulation of type 2 immune response	7.795843e-4
GO:0060384	innervation	8.088079e-4
GO:0033091	positive regulation of immature T cell proliferation	8.092693e-4
GO:0001959	regulation of cytokine-mediated signaling pathway	8.237637e-4
GO:0033131	regulation of glucokinase activity	8.304605e-4
GO:0042398	cellular modified amino acid biosynthetic process	8.314119e-4
GO:0006721	terpenoid metabolic process	8.375809e-4
GO:0009992	cellular water homeostasis	8.389676e-4
GO:0014827	intestine smooth muscle contraction	8.389676e-4
GO:0006591	ornithine metabolic process	8.389676e-4
GO:0044087	regulation of cellular component biogenesis	8.500707e-4
GO:0072422	signal transduction involved in DNA damage checkpoint	8.512159e-4
GO:0030967	ER-nuclear sterol response pathway	8.578069e-4
GO:0010717	regulation of epithelial to mesenchymal transition	8.628688e-4
GO:0048709	oligodendrocyte differentiation	8.631548e-4
GO:0014896	muscle hypertrophy	8.801555e-4
GO:0010470	regulation of gastrulation	8.818942e-4
GO:0007399	nervous system development	8.835835e-4
GO:0070252	actin-mediated cell contraction	8.839797e-4
GO:0051930	regulation of sensory perception of pain	8.879197e-4
GO:0071417	cellular response to organic nitrogen	8.934593e-4
GO:0046949	fatty-acyl-CoA biosynthetic process	8.950638e-4
GO:0035338	long-chain fatty-acyl-CoA biosynthetic process	9.124210e-4
GO:0010629	negative regulation of gene expression	9.497347e-4
GO:0006690	icosanoid metabolic process	9.517415e-4
GO:0051129	negative regulation of cellular component organization	9.537126e-4
GO:0071875	adrenergic receptor signaling pathway	9.698751e-4
GO:0014848	urinary tract smooth muscle contraction	9.716112e-4
GO:0051592	response to calcium ion	9.765884e-4
GO:0043525	positive regulation of neuron apoptosis	9.865457e-4
GO:0051355	proprioception involved in equilibrioception	9.922183e-4
GO:0016446	somatic hypermutation of immunoglobulin genes	1.006001e-3
GO:0030049	muscle filament sliding	1.012903e-3
GO:0030834	regulation of actin filament depolymerization	1.014191e-3
GO:0042313	protein kinase C deactivation	1.020677e-3
GO:0031583	activation of phospholipase D activity by G-protein coupled receptor protein signaling pathway	1.020677e-3
GO:0001819	positive regulation of cytokine production	1.027804e-3
GO:0045046	protein import into peroxisome membrane	1.042263e-3
GO:0051347	positive regulation of transferase activity	1.048252e-3
GO:0002756	MyD88-independent toll-like receptor signaling pathway	1.053899e-3
GO:0060298	positive regulation of sarcomere organization	1.097798e-3
GO:0051310	metaphase plate congression	1.101845e-3
GO:0060284	regulation of cell development	1.129728e-3
GO:0045404	positive regulation of interleukin-4 biosynthetic process	1.129822e-3
GO:0060730	regulation of intestinal epithelial structure maintenance	1.159028e-3
GO:0060398	regulation of growth hormone receptor signaling pathway	1.169003e-3
GO:0009790	embryo development	1.190186e-3
GO:0006636	unsaturated fatty acid biosynthetic process	1.198559e-3
GO:0042510	regulation of tyrosine phosphorylation of Stat1 protein	1.212639e-3
GO:0015697	quaternary ammonium group transport	1.216573e-3
GO:0045773	positive regulation of axon extension	1.222302e-3
GO:0071418	cellular response to amine stimulus	1.249361e-3
GO:0032525	somite rostral/caudal axis specification	1.268077e-3
GO:0090399	replicative senescence	1.268077e-3
GO:0007163	establishment or maintenance of cell polarity	1.279395e-3
GO:0031347	regulation of defense response	1.285752e-3
GO:0035809	regulation of urine volume	1.298582e-3
GO:0051209	release of sequestered calcium ion into cytosol	1.307807e-3
GO:0043549	regulation of kinase activity	1.323101e-3
GO:2000189	positive regulation of cholesterol homeostasis	1.323284e-3
GO:0031571	mitotic cell cycle G1/S transition DNA damage checkpoint	1.328839e-3
GO:0016584	nucleosome positioning	1.330159e-3
GO:0001955	blood vessel maturation	1.336540e-3
GO:0042551	neuron maturation	1.339918e-3
GO:0071243	cellular response to arsenic-containing substance	1.340240e-3
GO:0035092	sperm chromatin condensation	1.340240e-3
GO:0045084	positive regulation of interleukin-12 biosynthetic process	1.354654e-3
GO:0032878	regulation of establishment or maintenance of cell polarity	1.373126e-3
GO:0009200	deoxyribonucleoside triphosphate metabolic process	1.376547e-3
GO:0002790	peptide secretion	1.380885e-3
GO:0045787	positive regulation of cell cycle	1.384740e-3
GO:0071480	cellular response to gamma radiation	1.390679e-3
GO:0070201	regulation of establishment of protein localization	1.399114e-3
GO:0007352	zygotic specification of dorsal/ventral axis	1.408277e-3
GO:0072404	signal transduction involved in G1/S transition checkpoint	1.409164e-3
GO:0034661	ncRNA catabolic process	1.416914e-3
GO:0002553	histamine secretion by mast cell	1.416914e-3
GO:0051142	positive regulation of NK T cell proliferation	1.418933e-3
GO:0045143	homologous chromosome segregation	1.418933e-3
GO:0035582	negative regulation of BMP signaling pathway by extracellular sequestering of BMP	1.437151e-3
GO:0021702	cerebellar Purkinje cell differentiation	1.440456e-3
GO:0045727	positive regulation of translation	1.461716e-3
GO:0002224	toll-like receptor signaling pathway	1.466302e-3
GO:0006631	fatty acid metabolic process	1.508911e-3
GO:0042946	glucoside transport	1.515464e-3
GO:0072355	histone H3-T3 phosphorylation	1.515464e-3
GO:0019068	virion assembly	1.515464e-3
GO:0030166	proteoglycan biosynthetic process	1.534747e-3
GO:0019226	transmission of nerve impulse	1.535429e-3
GO:0048791	calcium ion-dependent exocytosis of neurotransmitter	1.544628e-3
GO:0042508	tyrosine phosphorylation of Stat1 protein	1.544628e-3
GO:0030833	regulation of actin filament polymerization	1.552589e-3
GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway	1.582336e-3
GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	1.587739e-3
GO:0015817	histidine transport	1.610976e-3
GO:0010966	regulation of phosphate transport	1.610976e-3
GO:0016572	histone phosphorylation	1.619236e-3
GO:0034138	toll-like receptor 3 signaling pathway	1.625600e-3
GO:0051480	cytosolic calcium ion homeostasis	1.633673e-3
GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin	1.644720e-3
GO:0048002	antigen processing and presentation of peptide antigen	1.653532e-3
GO:0060759	regulation of response to cytokine stimulus	1.673069e-3
GO:0003156	regulation of organ formation	1.673508e-3
GO:0048505	regulation of timing of cell differentiation	1.674953e-3
GO:0033160	positive regulation of protein import into nucleus, translocation	1.677617e-3
GO:0035556	intracellular signal transduction	1.681037e-3
GO:0043101	purine-containing compound salvage	1.699122e-3
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	1.702506e-3
GO:0071224	cellular response to peptidoglycan	1.710982e-3
GO:0002827	positive regulation of T-helper 1 type immune response	1.712228e-3
GO:2000111	positive regulation of macrophage apoptosis	1.751916e-3
GO:0045185	maintenance of protein location	1.761209e-3
GO:0042137	sequestering of neurotransmitter	1.774396e-3
GO:0032689	negative regulation of interferon-gamma production	1.813909e-3
GO:0090322	regulation of superoxide metabolic process	1.823704e-3
GO:0045628	regulation of T-helper 2 cell differentiation	1.826786e-3
GO:0070099	regulation of chemokine-mediated signaling pathway	1.829647e-3
GO:0022406	membrane docking	1.846951e-3
GO:0072395	signal transduction involved in cell cycle checkpoint	1.857401e-3
GO:2000114	regulation of establishment of cell polarity	1.890508e-3
GO:0045163	clustering of voltage-gated potassium channels	1.892766e-3
GO:0009880	embryonic pattern specification	1.896332e-3
GO:0051900	regulation of mitochondrial depolarization	1.898521e-3
GO:0051960	regulation of nervous system development	1.922853e-3
GO:0071214	cellular response to abiotic stimulus	1.925219e-3
GO:0002036	regulation of L-glutamate transport	1.935683e-3
GO:0048041	focal adhesion assembly	1.944046e-3
GO:0003218	cardiac left ventricle formation	1.969187e-3
GO:0006997	nucleus organization	1.972851e-3
GO:0046122	purine deoxyribonucleoside metabolic process	1.988986e-3
GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity	2.016127e-3
GO:0010605	negative regulation of macromolecule metabolic process	2.027667e-3
GO:0042506	tyrosine phosphorylation of Stat5 protein	2.032061e-3
GO:0048486	parasympathetic nervous system development	2.098691e-3
GO:0046427	positive regulation of JAK-STAT cascade	2.109848e-3
GO:0009743	response to carbohydrate stimulus	2.125090e-3
GO:0071374	cellular response to parathyroid hormone stimulus	2.139328e-3
GO:0032754	positive regulation of interleukin-5 production	2.180247e-3
GO:0001757	somite specification	2.182466e-3
GO:0051282	regulation of sequestering of calcium ion	2.206492e-3
GO:0048808	male genitalia morphogenesis	2.206828e-3
GO:0032730	positive regulation of interleukin-1 alpha production	2.209296e-3
GO:0007631	feeding behavior	2.276517e-3
GO:0000083	regulation of transcription involved in G1/S phase of mitotic cell cycle	2.286408e-3
GO:0051135	positive regulation of NK T cell activation	2.296799e-3
GO:0009120	deoxyribonucleoside metabolic process	2.296799e-3
GO:0050730	regulation of peptidyl-tyrosine phosphorylation	2.306454e-3
GO:0071316	cellular response to nicotine	2.320012e-3
GO:0006020	inositol metabolic process	2.337768e-3
GO:0048521	negative regulation of behavior	2.340362e-3
GO:0061387	regulation of extent of cell growth	2.340477e-3
GO:0030832	regulation of actin filament length	2.341446e-3
GO:0016119	carotene metabolic process	2.342584e-3
GO:0043308	eosinophil degranulation	2.342584e-3
GO:0051089	constitutive protein ectodomain proteolysis	2.342584e-3
GO:0032802	low-density lipoprotein particle receptor catabolic process	2.342584e-3
GO:0048705	skeletal system morphogenesis	2.396807e-3
GO:0010164	response to cesium ion	2.406749e-3
GO:0051925	regulation of calcium ion transport via voltage-gated calcium channel activity	2.480274e-3
GO:0006873	cellular ion homeostasis	2.491862e-3
GO:0032729	positive regulation of interferon-gamma production	2.492147e-3
GO:0046134	pyrimidine nucleoside biosynthetic process	2.494451e-3
GO:0042127	regulation of cell proliferation	2.497602e-3
GO:0006081	cellular aldehyde metabolic process	2.590144e-3
GO:0031111	negative regulation of microtubule polymerization or depolymerization	2.598671e-3
GO:0008064	regulation of actin polymerization or depolymerization	2.598892e-3
GO:0055075	potassium ion homeostasis	2.607850e-3
GO:0006855	drug transmembrane transport	2.607850e-3
GO:0000187	activation of MAPK activity	2.610893e-3
GO:0006564	L-serine biosynthetic process	2.640949e-3
GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification	2.640949e-3
GO:0071299	cellular response to vitamin A	2.694681e-3
GO:0034720	histone H3-K4 demethylation	2.721018e-3
GO:0009215	purine deoxyribonucleoside triphosphate metabolic process	2.756822e-3
GO:0060585	positive regulation of prostaglandin-endoperoxide synthase activity	2.756913e-3
GO:0034393	positive regulation of smooth muscle cell apoptosis	2.756913e-3
GO:0016568	chromatin modification	2.762257e-3
GO:0022010	central nervous system myelination	2.767795e-3
GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway	2.788986e-3
GO:0003099	positive regulation of the force of heart contraction by chemical signal	2.788986e-3
GO:0032760	positive regulation of tumor necrosis factor production	2.798644e-3
GO:0031274	positive regulation of pseudopodium assembly	2.811639e-3
GO:0045604	regulation of epidermal cell differentiation	2.844063e-3
GO:0043094	cellular metabolic compound salvage	2.873615e-3
GO:0034340	response to type I interferon	2.909589e-3
GO:0032642	regulation of chemokine production	2.911057e-3
GO:0070093	negative regulation of glucagon secretion	2.941083e-3
GO:0045859	regulation of protein kinase activity	2.961774e-3
GO:0043266	regulation of potassium ion transport	2.964667e-3
GO:0002262	myeloid cell homeostasis	2.965038e-3
GO:0001932	regulation of protein phosphorylation	2.990136e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0051494	negative regulation of cytoskeleton organization	1.026888e-12
GO:0010639	negative regulation of organelle organization	4.177309e-12
GO:0043242	negative regulation of protein complex disassembly	9.048587e-11
GO:0033043	regulation of organelle organization	9.424820e-11
GO:0006266	DNA ligation	1.101374e-9
GO:0043244	regulation of protein complex disassembly	1.864379e-9
GO:0051493	regulation of cytoskeleton organization	2.169678e-9
GO:0006910	phagocytosis, recognition	6.928631e-9
GO:0007026	negative regulation of microtubule depolymerization	9.268412e-9
GO:0031114	regulation of microtubule depolymerization	2.073192e-8
GO:0015876	acetyl-CoA transport	2.379384e-8
GO:0032312	regulation of ARF GTPase activity	3.782496e-8
GO:0051129	negative regulation of cellular component organization	3.789490e-8
GO:0048523	negative regulation of cellular process	8.307496e-8
GO:0045124	regulation of bone resorption	1.054245e-7
GO:0051126	negative regulation of actin nucleation	1.099384e-7
GO:0045780	positive regulation of bone resorption	1.106187e-7
GO:0035065	regulation of histone acetylation	1.403671e-7
GO:0032271	regulation of protein polymerization	1.423996e-7
GO:0046850	regulation of bone remodeling	1.453992e-7
GO:0051103	DNA ligation involved in DNA repair	2.258156e-7
GO:0032849	positive regulation of cellular pH reduction	2.267414e-7
GO:0060307	regulation of ventricular cardiomyocyte membrane repolarization	2.477071e-7
GO:0060299	negative regulation of sarcomere organization	2.477071e-7
GO:0031110	regulation of microtubule polymerization or depolymerization	2.666848e-7
GO:0001845	phagolysosome assembly	2.738477e-7
GO:0048519	negative regulation of biological process	3.958799e-7
GO:0032956	regulation of actin cytoskeleton organization	4.589495e-7
GO:0048856	anatomical structure development	6.949370e-7
GO:0030279	negative regulation of ossification	8.610474e-7
GO:0016557	peroxisome membrane biogenesis	9.346347e-7
GO:0032970	regulation of actin filament-based process	9.644188e-7
GO:0031111	negative regulation of microtubule polymerization or depolymerization	1.020097e-6
GO:0032846	positive regulation of homeostatic process	1.024643e-6
GO:2000756	regulation of peptidyl-lysine acetylation	1.307958e-6
GO:0008037	cell recognition	1.419094e-6
GO:0044091	membrane biogenesis	1.481641e-6
GO:0031056	regulation of histone modification	1.862610e-6
GO:0021954	central nervous system neuron development	1.984226e-6
GO:0048731	system development	3.135144e-6
GO:0034105	positive regulation of tissue remodeling	3.255926e-6
GO:0002526	acute inflammatory response	3.563636e-6
GO:0044087	regulation of cellular component biogenesis	4.064188e-6
GO:0032020	ISG15-protein conjugation	4.550113e-6
GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation	4.577621e-6
GO:0034103	regulation of tissue remodeling	5.058517e-6
GO:0010897	negative regulation of triglyceride catabolic process	6.724720e-6
GO:0010987	negative regulation of high-density lipoprotein particle clearance	6.724720e-6
GO:0006694	steroid biosynthetic process	8.038764e-6
GO:0070507	regulation of microtubule cytoskeleton organization	8.301505e-6
GO:0072384	organelle transport along microtubule	9.259675e-6
GO:0021953	central nervous system neuron differentiation	9.742441e-6
GO:0016998	cell wall macromolecule catabolic process	9.926329e-6
GO:0009817	defense response to fungus, incompatible interaction	1.060774e-5
GO:0015670	carbon dioxide transport	1.076222e-5
GO:0048513	organ development	1.419470e-5
GO:0033762	response to glucagon stimulus	1.488625e-5
GO:0007096	regulation of exit from mitosis	1.553171e-5
GO:0060560	developmental growth involved in morphogenesis	1.691520e-5
GO:0006288	base-excision repair, DNA ligation	1.709371e-5
GO:0006953	acute-phase response	1.776639e-5
GO:0031112	positive regulation of microtubule polymerization or depolymerization	1.800760e-5
GO:0032847	regulation of cellular pH reduction	1.894031e-5
GO:0008584	male gonad development	1.902101e-5
GO:0031947	negative regulation of glucocorticoid biosynthetic process	1.948161e-5
GO:0006642	triglyceride mobilization	2.038252e-5
GO:0035645	enteric smooth muscle cell differentiation	2.044373e-5
GO:0007497	posterior midgut development	2.044373e-5
GO:0009653	anatomical structure morphogenesis	2.214284e-5
GO:0035092	sperm chromatin condensation	2.307080e-5
GO:0032886	regulation of microtubule-based process	2.398158e-5
GO:0006612	protein targeting to membrane	2.412216e-5
GO:0030502	negative regulation of bone mineralization	2.503952e-5
GO:0006349	regulation of gene expression by genetic imprinting	2.516205e-5
GO:0060537	muscle tissue development	2.602483e-5
GO:0031116	positive regulation of microtubule polymerization	2.855346e-5
GO:0050764	regulation of phagocytosis	2.889199e-5
GO:0032912	negative regulation of transforming growth factor beta2 production	3.079896e-5
GO:0071874	cellular response to norepinephrine stimulus	3.256408e-5
GO:0070168	negative regulation of biomineral tissue development	3.366077e-5
GO:0046985	positive regulation of hemoglobin biosynthetic process	3.425993e-5
GO:0043973	histone H3-K4 acetylation	3.425993e-5
GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery	3.425993e-5
GO:0048522	positive regulation of cellular process	3.686621e-5
GO:0002088	lens development in camera-type eye	3.798525e-5
GO:0006909	phagocytosis	3.876500e-5
GO:0030833	regulation of actin filament polymerization	3.914920e-5
GO:0032502	developmental process	4.170326e-5
GO:0003309	type B pancreatic cell differentiation	4.278433e-5
GO:0014706	striated muscle tissue development	4.623942e-5
GO:0070306	lens fiber cell differentiation	5.037374e-5
GO:0021506	anterior neuropore closure	5.189641e-5
GO:0050793	regulation of developmental process	5.838060e-5
GO:0010763	positive regulation of fibroblast migration	6.586753e-5
GO:0010982	regulation of high-density lipoprotein particle clearance	6.604405e-5
GO:0032870	cellular response to hormone stimulus	6.713965e-5
GO:0035247	peptidyl-arginine omega-N-methylation	6.825130e-5
GO:0043267	negative regulation of potassium ion transport	6.974997e-5
GO:0051693	actin filament capping	7.149297e-5
GO:0060575	intestinal epithelial cell differentiation	7.234250e-5
GO:0043266	regulation of potassium ion transport	7.654333e-5
GO:0000060	protein import into nucleus, translocation	8.251407e-5
GO:0043254	regulation of protein complex assembly	8.860976e-5
GO:0006991	response to sterol depletion	8.871314e-5
GO:0042304	regulation of fatty acid biosynthetic process	8.967905e-5
GO:0071425	hemopoietic stem cell proliferation	9.334340e-5
GO:0060215	primitive hemopoiesis	9.334340e-5
GO:0043932	ossification involved in bone remodeling	9.699436e-5
GO:0035093	spermatogenesis, exchange of chromosomal proteins	9.699436e-5
GO:0031060	regulation of histone methylation	1.035814e-4
GO:0010989	negative regulation of low-density lipoprotein particle clearance	1.134856e-4
GO:0016126	sterol biosynthetic process	1.150287e-4
GO:0047497	mitochondrion transport along microtubule	1.158041e-4
GO:0071495	cellular response to endogenous stimulus	1.208884e-4
GO:0002513	tolerance induction to self antigen	1.260926e-4
GO:0051150	regulation of smooth muscle cell differentiation	1.269583e-4
GO:0051890	regulation of cardioblast differentiation	1.280690e-4
GO:0030832	regulation of actin filament length	1.289399e-4
GO:0034969	histone arginine methylation	1.341424e-4
GO:0033044	regulation of chromosome organization	1.352100e-4
GO:0021955	central nervous system neuron axonogenesis	1.378257e-4
GO:0008202	steroid metabolic process	1.405769e-4
GO:0009957	epidermal cell fate specification	1.419670e-4
GO:0051654	establishment of mitochondrion localization	1.535693e-4
GO:0003310	pancreatic A cell differentiation	1.576478e-4
GO:0046661	male sex differentiation	1.614876e-4
GO:0033133	positive regulation of glucokinase activity	1.875410e-4
GO:0051915	induction of synaptic plasticity by chemical substance	1.940611e-4
GO:0032535	regulation of cellular component size	1.943909e-4
GO:0006003	fructose 2,6-bisphosphate metabolic process	1.948592e-4
GO:0046627	negative regulation of insulin receptor signaling pathway	1.952781e-4
GO:0006780	uroporphyrinogen III biosynthetic process	2.054633e-4
GO:0050907	detection of chemical stimulus involved in sensory perception	2.060268e-4
GO:0032965	regulation of collagen biosynthetic process	2.138514e-4
GO:0006805	xenobiotic metabolic process	2.170855e-4
GO:0051258	protein polymerization	2.173881e-4
GO:0045922	negative regulation of fatty acid metabolic process	2.194747e-4
GO:0007275	multicellular organismal development	2.202211e-4
GO:0060065	uterus development	2.215778e-4
GO:0042443	phenylethylamine metabolic process	2.493362e-4
GO:0070165	positive regulation of adiponectin secretion	2.493362e-4
GO:0033031	positive regulation of neutrophil apoptosis	2.493362e-4
GO:0007417	central nervous system development	2.495563e-4
GO:0003205	cardiac chamber development	2.539607e-4
GO:0060430	lung saccule development	2.560975e-4
GO:0051180	vitamin transport	2.578688e-4
GO:0071158	positive regulation of cell cycle arrest	2.647484e-4
GO:0032353	negative regulation of hormone biosynthetic process	2.712283e-4
GO:0008064	regulation of actin polymerization or depolymerization	2.716774e-4
GO:0007062	sister chromatid cohesion	2.750206e-4
GO:0035587	purinergic receptor signaling pathway	2.759832e-4
GO:0032967	positive regulation of collagen biosynthetic process	2.781900e-4
GO:0048518	positive regulation of biological process	2.786462e-4
GO:0051145	smooth muscle cell differentiation	2.877306e-4
GO:0030225	macrophage differentiation	2.962931e-4
GO:0003231	cardiac ventricle development	2.976677e-4
GO:0046546	development of primary male sexual characteristics	2.997994e-4
GO:0072592	oxygen metabolic process	3.005456e-4
GO:0015889	cobalamin transport	3.005456e-4
GO:2000426	negative regulation of apoptotic cell clearance	3.060324e-4
GO:0050765	negative regulation of phagocytosis	3.093677e-4
GO:0030967	ER-nuclear sterol response pathway	3.114620e-4
GO:0021952	central nervous system projection neuron axonogenesis	3.252603e-4
GO:0050911	detection of chemical stimulus involved in sensory perception of smell	3.337846e-4
GO:0031113	regulation of microtubule polymerization	3.341941e-4
GO:0017085	response to insecticide	3.569128e-4
GO:0090209	negative regulation of triglyceride metabolic process	3.591975e-4
GO:0060762	regulation of branching involved in mammary gland duct morphogenesis	3.591975e-4
GO:0030835	negative regulation of actin filament depolymerization	3.607233e-4
GO:0048608	reproductive structure development	3.786446e-4
GO:0021702	cerebellar Purkinje cell differentiation	3.792440e-4
GO:0009743	response to carbohydrate stimulus	3.890117e-4
GO:0046626	regulation of insulin receptor signaling pathway	3.927706e-4
GO:0031536	positive regulation of exit from mitosis	3.965942e-4
GO:0032796	uropod organization	4.004741e-4
GO:0035066	positive regulation of histone acetylation	4.048464e-4
GO:0070542	response to fatty acid	4.124793e-4
GO:0050766	positive regulation of phagocytosis	4.258125e-4
GO:0070163	regulation of adiponectin secretion	4.295700e-4
GO:0045046	protein import into peroxisome membrane	4.327569e-4
GO:0021986	habenula development	4.327569e-4
GO:0021501	prechordal plate formation	4.327569e-4
GO:0021547	midbrain-hindbrain boundary initiation	4.327569e-4
GO:0035590	purinergic nucleotide receptor signaling pathway	4.376352e-4
GO:0016049	cell growth	4.449832e-4
GO:0051152	positive regulation of smooth muscle cell differentiation	4.459179e-4
GO:0035246	peptidyl-arginine N-methylation	4.489149e-4
GO:0051241	negative regulation of multicellular organismal process	4.500361e-4
GO:0031327	negative regulation of cellular biosynthetic process	4.609099e-4
GO:0055012	ventricular cardiac muscle cell differentiation	4.649945e-4
GO:0045717	negative regulation of fatty acid biosynthetic process	4.718821e-4
GO:0045806	negative regulation of endocytosis	4.959729e-4
GO:0045819	positive regulation of glycogen catabolic process	5.004006e-4
GO:0048676	axon extension involved in development	5.201535e-4
GO:0046849	bone remodeling	5.358115e-4
GO:0032012	regulation of ARF protein signal transduction	5.472873e-4
GO:0006071	glycerol metabolic process	5.497607e-4
GO:0030500	regulation of bone mineralization	5.499985e-4
GO:0008284	positive regulation of cell proliferation	5.587018e-4
GO:0060621	negative regulation of cholesterol import	5.696426e-4
GO:0035588	G-protein coupled purinergic receptor signaling pathway	5.711435e-4
GO:0048820	hair follicle maturation	5.881787e-4
GO:0032273	positive regulation of protein polymerization	5.896813e-4
GO:0071379	cellular response to prostaglandin stimulus	5.906655e-4
GO:0046984	regulation of hemoglobin biosynthetic process	6.006382e-4
GO:0019915	lipid storage	6.095221e-4
GO:0071542	dopaminergic neuron differentiation	6.096174e-4
GO:0070309	lens fiber cell morphogenesis	6.096174e-4
GO:0018216	peptidyl-arginine methylation	6.252476e-4
GO:0033260	DNA replication involved in S phase	6.258985e-4
GO:0032854	positive regulation of Rap GTPase activity	6.270904e-4
GO:0032025	response to cobalt ion	6.270904e-4
GO:0032501	multicellular organismal process	6.353914e-4
GO:0010744	positive regulation of macrophage derived foam cell differentiation	6.377358e-4
GO:0034612	response to tumor necrosis factor	6.401321e-4
GO:0051707	response to other organism	6.529508e-4
GO:0045595	regulation of cell differentiation	6.603651e-4
GO:0009826	unidimensional cell growth	6.625380e-4
GO:0018916	nitrobenzene metabolic process	6.969914e-4
GO:0034276	kynurenic acid biosynthetic process	6.969914e-4
GO:0002534	cytokine production involved in inflammatory response	6.969914e-4
GO:0007493	endodermal cell fate determination	7.331829e-4
GO:0032660	regulation of interleukin-17 production	7.342311e-4
GO:0007621	negative regulation of female receptivity	7.766624e-4
GO:0071695	anatomical structure maturation	7.770736e-4
GO:0003417	growth plate cartilage development	7.919776e-4
GO:0061162	establishment of monopolar cell polarity	7.949003e-4
GO:0045670	regulation of osteoclast differentiation	7.987295e-4
GO:0044089	positive regulation of cellular component biogenesis	8.076876e-4
GO:0048484	enteric nervous system development	8.154205e-4
GO:0046874	quinolinate metabolic process	8.221100e-4
GO:0051963	regulation of synapse assembly	8.223817e-4
GO:0060319	primitive erythrocyte differentiation	8.454251e-4
GO:0001560	regulation of cell growth by extracellular stimulus	8.623418e-4
GO:0032911	negative regulation of transforming growth factor beta1 production	8.775479e-4
GO:0042178	xenobiotic catabolic process	8.775479e-4
GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway	8.880479e-4
GO:0043277	apoptotic cell clearance	8.883286e-4
GO:0010638	positive regulation of organelle organization	9.226200e-4
GO:0031324	negative regulation of cellular metabolic process	9.368765e-4
GO:0090066	regulation of anatomical structure size	9.423616e-4
GO:0060045	positive regulation of cardiac muscle cell proliferation	9.690835e-4
GO:0034421	post-translational protein acetylation	9.923395e-4
GO:0031946	regulation of glucocorticoid biosynthetic process	9.983283e-4
GO:0019400	alditol metabolic process	9.996992e-4
GO:0046620	regulation of organ growth	1.008668e-3
GO:0009593	detection of chemical stimulus	1.012703e-3
GO:0070167	regulation of biomineral tissue development	1.018477e-3
GO:0048738	cardiac muscle tissue development	1.034297e-3
GO:0051094	positive regulation of developmental process	1.035076e-3
GO:0071221	cellular response to bacterial lipopeptide	1.041888e-3
GO:0019433	triglyceride catabolic process	1.042322e-3
GO:0007018	microtubule-based movement	1.048556e-3
GO:0032693	negative regulation of interleukin-10 production	1.051937e-3
GO:0051093	negative regulation of developmental process	1.056285e-3
GO:0007431	salivary gland development	1.068097e-3
GO:0032740	positive regulation of interleukin-17 production	1.074263e-3
GO:2000744	positive regulation of anterior head development	1.092681e-3
GO:0048733	sebaceous gland development	1.109417e-3
GO:0007529	establishment of synaptic specificity at neuromuscular junction	1.109417e-3
GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine	1.109417e-3
GO:0051181	cofactor transport	1.135117e-3
GO:0010646	regulation of cell communication	1.164107e-3
GO:0009890	negative regulation of biosynthetic process	1.165625e-3
GO:0045833	negative regulation of lipid metabolic process	1.167814e-3
GO:0046677	response to antibiotic	1.177135e-3
GO:0048505	regulation of timing of cell differentiation	1.177586e-3
GO:0061061	muscle structure development	1.182554e-3
GO:0045934	negative regulation of nucleobase-containing compound metabolic process	1.189305e-3
GO:0060620	regulation of cholesterol import	1.224412e-3
GO:0010970	microtubule-based transport	1.227929e-3
GO:0043654	recognition of apoptotic cell	1.232932e-3
GO:0045926	negative regulation of growth	1.235754e-3
GO:0003416	endochondral bone growth	1.237250e-3
GO:0071371	cellular response to gonadotropin stimulus	1.245122e-3
GO:0005981	regulation of glycogen catabolic process	1.257074e-3
GO:0070228	regulation of lymphocyte apoptosis	1.325254e-3
GO:0051570	regulation of histone H3-K9 methylation	1.329231e-3
GO:0006703	estrogen biosynthetic process	1.339558e-3
GO:0051965	positive regulation of synapse assembly	1.351799e-3
GO:0051891	positive regulation of cardioblast differentiation	1.394537e-3
GO:0050925	negative regulation of negative chemotaxis	1.410686e-3
GO:0010936	negative regulation of macrophage cytokine production	1.410686e-3
GO:0006090	pyruvate metabolic process	1.411029e-3
GO:0042159	lipoprotein catabolic process	1.415520e-3
GO:0031058	positive regulation of histone modification	1.427131e-3
GO:0002524	hypersensitivity	1.452253e-3
GO:0034383	low-density lipoprotein particle clearance	1.500473e-3
GO:0045623	negative regulation of T-helper cell differentiation	1.510086e-3
GO:0009888	tissue development	1.514076e-3
GO:0010740	positive regulation of intracellular protein kinase cascade	1.515268e-3
GO:0002719	negative regulation of cytokine production involved in immune response	1.554696e-3
GO:0010935	regulation of macrophage cytokine production	1.560403e-3
GO:0006695	cholesterol biosynthetic process	1.585765e-3
GO:0001818	negative regulation of cytokine production	1.593921e-3
GO:0030834	regulation of actin filament depolymerization	1.634136e-3
GO:0045629	negative regulation of T-helper 2 cell differentiation	1.635020e-3
GO:0051953	negative regulation of amine transport	1.666723e-3
GO:0060744	mammary gland branching involved in thelarche	1.711247e-3
GO:0033151	V(D)J recombination	1.723154e-3
GO:0010907	positive regulation of glucose metabolic process	1.724732e-3
GO:0007507	heart development	1.731102e-3
GO:0051154	negative regulation of striated muscle cell differentiation	1.750616e-3
GO:0090100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	1.771260e-3
GO:0051253	negative regulation of RNA metabolic process	1.781643e-3
GO:0033013	tetrapyrrole metabolic process	1.791635e-3
GO:0061370	testosterone biosynthetic process	1.798619e-3
GO:0043627	response to estrogen stimulus	1.799435e-3
GO:0009617	response to bacterium	1.799861e-3
GO:0043029	T cell homeostasis	1.824567e-3
GO:0010886	positive regulation of cholesterol storage	1.862136e-3
GO:0001654	eye development	1.864641e-3
GO:0002089	lens morphogenesis in camera-type eye	1.879420e-3
GO:0060510	Type II pneumocyte differentiation	1.922047e-3
GO:0048565	digestive tract development	1.943409e-3
GO:0048545	response to steroid hormone stimulus	1.943879e-3
GO:0070670	response to interleukin-4	1.954362e-3
GO:0007076	mitotic chromosome condensation	1.966938e-3
GO:0009048	dosage compensation, by inactivation of X chromosome	1.969038e-3
GO:0045628	regulation of T-helper 2 cell differentiation	1.974240e-3
GO:0045471	response to ethanol	1.984454e-3
GO:0014732	skeletal muscle atrophy	1.988408e-3
GO:0040034	regulation of development, heterochronic	2.045394e-3
GO:0007210	serotonin receptor signaling pathway	2.049956e-3
GO:0007204	elevation of cytosolic calcium ion concentration	2.061389e-3
GO:0034694	response to prostaglandin stimulus	2.085258e-3
GO:0060538	skeletal muscle organ development	2.107020e-3
GO:0071985	multivesicular body sorting pathway	2.112836e-3
GO:0009134	nucleoside diphosphate catabolic process	2.125588e-3
GO:0009725	response to hormone stimulus	2.141108e-3
GO:0019218	regulation of steroid metabolic process	2.166071e-3
GO:0048633	positive regulation of skeletal muscle tissue growth	2.168710e-3
GO:0033604	negative regulation of catecholamine secretion	2.181684e-3
GO:0006778	porphyrin-containing compound metabolic process	2.211199e-3
GO:0046425	regulation of JAK-STAT cascade	2.289193e-3
GO:0001702	gastrulation with mouth forming second	2.304383e-3
GO:0033131	regulation of glucokinase activity	2.312095e-3
GO:0071870	cellular response to catecholamine stimulus	2.319013e-3
GO:0045056	transcytosis	2.319013e-3
GO:0032318	regulation of Ras GTPase activity	2.334400e-3
GO:0051188	cofactor biosynthetic process	2.360445e-3
GO:0070245	positive regulation of thymocyte apoptosis	2.389357e-3
GO:0051172	negative regulation of nitrogen compound metabolic process	2.394525e-3
GO:0060900	embryonic camera-type eye formation	2.435697e-3
GO:0051125	regulation of actin nucleation	2.441835e-3
GO:0051055	negative regulation of lipid biosynthetic process	2.450324e-3
GO:0031061	negative regulation of histone methylation	2.452539e-3
GO:2000758	positive regulation of peptidyl-lysine acetylation	2.493667e-3
GO:0070307	lens fiber cell development	2.520847e-3
GO:0050706	regulation of interleukin-1 beta secretion	2.551834e-3
GO:2000021	regulation of ion homeostasis	2.578799e-3
GO:0042692	muscle cell differentiation	2.579797e-3
GO:0003208	cardiac ventricle morphogenesis	2.629510e-3
GO:0045892	negative regulation of transcription, DNA-dependent	2.634816e-3
GO:0032317	regulation of Rap GTPase activity	2.639862e-3
GO:0044246	regulation of multicellular organismal metabolic process	2.653465e-3
GO:0050808	synapse organization	2.662874e-3
GO:0003334	keratinocyte development	2.674335e-3
GO:0001780	neutrophil homeostasis	2.677764e-3
GO:0050678	regulation of epithelial cell proliferation	2.681665e-3
GO:0021700	developmental maturation	2.708918e-3
GO:0060338	regulation of type I interferon-mediated signaling pathway	2.719692e-3
GO:0031579	membrane raft organization	2.719692e-3
GO:0019934	cGMP-mediated signaling	2.738305e-3
GO:0001578	microtubule bundle formation	2.771364e-3
GO:0021510	spinal cord development	2.813855e-3
GO:0051447	negative regulation of meiotic cell cycle	2.826011e-3
GO:0006844	acyl carnitine transport	2.826011e-3
GO:0001552	ovarian follicle atresia	2.826011e-3
GO:0021836	chemorepulsion involved in postnatal olfactory bulb interneuron migration	2.877262e-3
GO:2000106	regulation of leukocyte apoptosis	2.888143e-3
GO:0007435	salivary gland morphogenesis	2.901711e-3
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	2.910839e-3
GO:0043065	positive regulation of apoptosis	2.940931e-3
GO:0070875	positive regulation of glycogen metabolic process	2.941277e-3
GO:0045672	positive regulation of osteoclast differentiation	2.949883e-3
GO:0050679	positive regulation of epithelial cell proliferation	2.953507e-3
GO:0051480	cytosolic calcium ion homeostasis	2.953507e-3
GO:0045591	positive regulation of regulatory T cell differentiation	3.006326e-3
GO:0046427	positive regulation of JAK-STAT cascade	3.080079e-3
GO:0014889	muscle atrophy	3.086182e-3
GO:0097115	neurexin clustering	3.089346e-3
GO:0043951	negative regulation of cAMP-mediated signaling	3.135525e-3
GO:0009235	cobalamin metabolic process	3.135525e-3
GO:0055007	cardiac muscle cell differentiation	3.218707e-3
GO:0040008	regulation of growth	3.269761e-3
GO:0051001	negative regulation of nitric-oxide synthase activity	3.276661e-3
GO:0072358	cardiovascular system development	3.304326e-3
GO:0030837	negative regulation of actin filament polymerization	3.349591e-3
GO:0007416	synapse assembly	3.368888e-3
GO:0090199	regulation of release of cytochrome c from mitochondria	3.369333e-3
GO:0048521	negative regulation of behavior	3.398468e-3
GO:0007221	positive regulation of transcription of Notch receptor target	3.406824e-3
GO:0002701	negative regulation of production of molecular mediator of immune response	3.414501e-3
GO:0048813	dendrite morphogenesis	3.427124e-3
GO:0048869	cellular developmental process	3.436746e-3
GO:0014043	negative regulation of neuron maturation	3.442266e-3
GO:2000515	negative regulation of CD4-positive, alpha-beta T cell activation	3.449250e-3
GO:0051146	striated muscle cell differentiation	3.487044e-3
GO:0010894	negative regulation of steroid biosynthetic process	3.598502e-3
GO:0032355	response to estradiol stimulus	3.607661e-3
GO:0042523	positive regulation of tyrosine phosphorylation of Stat5 protein	3.703341e-3
GO:0031929	TOR signaling cascade	3.729718e-3
GO:0043370	regulation of CD4-positive, alpha-beta T cell differentiation	3.751605e-3
GO:0051901	positive regulation of mitochondrial depolarization	3.798464e-3
GO:0031062	positive regulation of histone methylation	3.828878e-3
GO:0070234	positive regulation of T cell apoptosis	3.832062e-3
GO:0006824	cobalt ion transport	3.863497e-3
GO:0031057	negative regulation of histone modification	3.891946e-3
GO:0010628	positive regulation of gene expression	3.899558e-3
GO:0009410	response to xenobiotic stimulus	3.905258e-3
GO:0030308	negative regulation of cell growth	3.954612e-3
GO:0044253	positive regulation of multicellular organismal metabolic process	3.980078e-3
GO:0019216	regulation of lipid metabolic process	3.987283e-3
GO:0047496	vesicle transport along microtubule	3.992349e-3
GO:0046503	glycerolipid catabolic process	4.003147e-3
GO:0043068	positive regulation of programmed cell death	4.018172e-3
GO:2000425	regulation of apoptotic cell clearance	4.091831e-3
GO:0042520	positive regulation of tyrosine phosphorylation of Stat4 protein	4.091831e-3
GO:0071711	basement membrane organization	4.091831e-3
GO:0009892	negative regulation of metabolic process	4.096463e-3
GO:0030100	regulation of endocytosis	4.119505e-3
GO:0010884	positive regulation of lipid storage	4.185907e-3
GO:0021869	forebrain ventricular zone progenitor cell division	4.199703e-3
GO:0007399	nervous system development	4.251329e-3
GO:0001558	regulation of cell growth	4.293642e-3
GO:0031943	regulation of glucocorticoid metabolic process	4.310884e-3
GO:0009404	toxin metabolic process	4.310884e-3
GO:0032909	regulation of transforming growth factor beta2 production	4.342000e-3
GO:0070252	actin-mediated cell contraction	4.353951e-3
GO:0007519	skeletal muscle tissue development	4.362175e-3
GO:0060420	regulation of heart growth	4.463646e-3
GO:0010676	positive regulation of cellular carbohydrate metabolic process	4.503890e-3
GO:0033275	actin-myosin filament sliding	4.509269e-3
GO:0045766	positive regulation of angiogenesis	4.612821e-3
GO:0051182	coenzyme transport	4.632941e-3
GO:0002237	response to molecule of bacterial origin	4.638875e-3
GO:0010942	positive regulation of cell death	4.655812e-3
GO:0045597	positive regulation of cell differentiation	4.724524e-3
GO:0018364	peptidyl-glutamine methylation	4.741087e-3
GO:0061381	cell migration in diencephalon	4.743164e-3
GO:0061379	inferior colliculus development	4.743164e-3
GO:0061374	mammillothalamic axonal tract development	4.743164e-3
GO:0021855	hypothalamus cell migration	4.743164e-3
GO:2000113	negative regulation of cellular macromolecule biosynthetic process	4.767595e-3
GO:0071514	genetic imprinting	4.788247e-3
GO:0021697	cerebellar cortex formation	4.818137e-3
GO:0006599	phosphagen metabolic process	4.825419e-3
GO:0032876	negative regulation of DNA endoreduplication	4.834369e-3
GO:0060043	regulation of cardiac muscle cell proliferation	4.888528e-3
GO:0002718	regulation of cytokine production involved in immune response	4.888528e-3
GO:0021846	cell proliferation in forebrain	4.917185e-3
GO:0050704	regulation of interleukin-1 secretion	4.983932e-3
GO:0021827	postnatal olfactory bulb interneuron migration	5.041844e-3
GO:0002699	positive regulation of immune effector process	5.103199e-3
GO:0003279	cardiac septum development	5.127620e-3
GO:0007494	midgut development	5.163133e-3
GO:0006954	inflammatory response	5.260750e-3
GO:0046835	carbohydrate phosphorylation	5.280082e-3
GO:0060540	diaphragm morphogenesis	5.293004e-3
GO:0060464	lung lobe formation	5.293004e-3
GO:0043623	cellular protein complex assembly	5.395809e-3
GO:0048592	eye morphogenesis	5.450111e-3
GO:0090104	pancreatic E cell differentiation	5.483511e-3
GO:0006798	polyphosphate catabolic process	5.483511e-3
GO:0003311	pancreatic D cell differentiation	5.483511e-3
GO:0001889	liver development	5.511704e-3
GO:0019751	polyol metabolic process	5.528429e-3
GO:0060297	regulation of sarcomere organization	5.651325e-3
GO:0019049	evasion of host defenses by virus	5.664062e-3
GO:2000514	regulation of CD4-positive, alpha-beta T cell activation	5.717801e-3
GO:0070232	regulation of T cell apoptosis	5.717801e-3
GO:0042522	regulation of tyrosine phosphorylation of Stat5 protein	5.730578e-3
GO:0048246	macrophage chemotaxis	5.774669e-3
GO:0008207	C21-steroid hormone metabolic process	5.795968e-3
GO:0045410	positive regulation of interleukin-6 biosynthetic process	5.800378e-3
GO:0042699	follicle-stimulating hormone signaling pathway	5.800378e-3
GO:0002572	pro-T cell differentiation	5.800378e-3
GO:0009607	response to biotic stimulus	5.804786e-3
GO:0009308	amine metabolic process	5.885350e-3
GO:0048384	retinoic acid receptor signaling pathway	5.934964e-3
GO:0061351	neural precursor cell proliferation	5.967989e-3
GO:0021879	forebrain neuron differentiation	6.000796e-3
GO:0048638	regulation of developmental growth	6.003628e-3
GO:0044242	cellular lipid catabolic process	6.010699e-3
GO:0061037	negative regulation of cartilage development	6.060120e-3
GO:0051497	negative regulation of stress fiber assembly	6.072311e-3
GO:0030879	mammary gland development	6.094380e-3
GO:0010627	regulation of intracellular protein kinase cascade	6.190542e-3
GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan	6.203437e-3
GO:0070873	regulation of glycogen metabolic process	6.331787e-3
GO:0016338	calcium-independent cell-cell adhesion	6.361688e-3
GO:0007156	homophilic cell adhesion	6.421513e-3
GO:0030154	cell differentiation	6.429792e-3
GO:0030002	cellular anion homeostasis	6.433256e-3
GO:2000026	regulation of multicellular organismal development	6.464605e-3
GO:0043534	blood vessel endothelial cell migration	6.554772e-3
GO:0048588	developmental cell growth	6.722246e-3
GO:0033993	response to lipid	6.753326e-3
GO:0046543	development of secondary female sexual characteristics	6.831714e-3