UBERON:0001777
From FANTOM5_SSTAR
Name: | substantia propria of cornea | |
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Namespace: | FANTOM | |
Definition: | "The substantia propria (or stroma of cornea) is fibrous, tough, unyielding, and perfectly transparent. It is composed of about 200 flattened lamell��スヲ (plates of collagen fibrils), superimposed one on another. They are each about 1.5-2.5 micrometres in thickness. These fibrils run at different angles between the limbi. Fibres of the layers frequently interweave, the anterior lamell��スヲ interweaving more than posterior lamell��スヲ. The fibres of each lamella are parallel with one another, but at right angles to those of adjacent lamell��スヲ. The lamell��スヲ are produced by keratocytes (corneal corpuscles), which occupy about 10% of the substantia propria. These lamell��スヲ are made up of bundles of modified connective tissue, the fibres of which are directly continuous with those of the sclera. More collagen fibres run in a temporal-nasal direction than run in the superior-inferior direction. This is often ignored by corneal transplant surgeons, leading to poor corneal mechanical strength in corneal transplant patients. [WP,unvetted]." [Wikipedia:Corneal_stroma] | |
Xrefs: |
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Synonyms: |
"cornea stroma" EXACT [] "corneal stroma" EXACT [] "stroma of cornea" EXACT [] "substantia propria" RELATED [] | |
Comments: | This class was created automatically from a combination of ontologies | |
Alt_id: | UBERON:FMA_58306-MA_0001245 | |
Subset: |
uberon_slim vertebrate_core |
Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data
Parents
is_a: | UBERON:0003891(stroma),UBERON:0010313(neural crest-derived structure) |
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develops_from: | UBERON:0007213(mesenchyme derived from head neural crest) |
part_of: | UBERON:0000964(cornea) |
Children
part of: | CL:0002363 (keratocyte) |
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Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology
Human (Homo sapiens)
- 11527-119I6 (Keratocytes, donor1)
- 11607-120I5 (Keratocytes, donor2)
- 11688-122I5 (Keratocytes, donor3)
Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0001777 (substantia propria of cornea), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data
Property "Property value" (as page type) with input value "UBPROP:0000001 "Portion of tissue that is located basal to Bowman's layer and distal to Descemet's membrane and is comprised largely of connective tissue.[TAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.