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UBERON:0001777

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Name:substantia propria of cornea
Namespace:FANTOM
Definition:"The substantia propria (or stroma of cornea) is fibrous, tough, unyielding, and perfectly transparent. It is composed of about 200 flattened lamell��スヲ (plates of collagen fibrils), superimposed one on another. They are each about 1.5-2.5 micrometres in thickness. These fibrils run at different angles between the limbi. Fibres of the layers frequently interweave, the anterior lamell��スヲ interweaving more than posterior lamell��スヲ. The fibres of each lamella are parallel with one another, but at right angles to those of adjacent lamell��スヲ. The lamell��スヲ are produced by keratocytes (corneal corpuscles), which occupy about 10% of the substantia propria. These lamell��スヲ are made up of bundles of modified connective tissue, the fibres of which are directly continuous with those of the sclera. More collagen fibres run in a temporal-nasal direction than run in the superior-inferior direction. This is often ignored by corneal transplant surgeons, leading to poor corneal mechanical strength in corneal transplant patients. [WP,unvetted]." [Wikipedia:Corneal_stroma]
Xrefs:
links:

EFO:0002514
EMAPA:17602
FMA:58306
GAID:893
[ 200px-Gray871.png 200px-Gray871.png]
MA:0001245
MESH:A.09.371.060.217.228
ncithesaurus:Corneal_Stroma
SCTID:362511000
TAO:0002189

ZFA:0001685
Synonyms: "cornea stroma" EXACT []
"corneal stroma" EXACT []
"stroma of cornea" EXACT []
"substantia propria" RELATED []
Comments:This class was created automatically from a combination of ontologies
Alt_id: UBERON:FMA_58306-MA_0001245
Subset: uberon_slim
vertebrate_core

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data


Parents

is_a:UBERON:0003891(stroma),UBERON:0010313(neural crest-derived structure)
develops_from:UBERON:0007213(mesenchyme derived from head neural crest)
part_of:UBERON:0000964(cornea)



Children

part of:CL:0002363 (keratocyte)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology


Human (Homo sapiens)


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0001777 (substantia propria of cornea), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data











Property "Property value" (as page type) with input value "UBPROP:0000001 "Portion of tissue that is located basal to Bowman's layer and distal to Descemet's membrane and is comprised largely of connective tissue.[TAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.