UBERON:0001777
From FANTOM5_SSTAR
| Name: | substantia propria of cornea | ||
|---|---|---|---|
| Namespace: | FANTOM | ||
| Definition: | "The substantia propria (or stroma of cornea) is fibrous, tough, unyielding, and perfectly transparent. It is composed of about 200 flattened lamell��ｽｦ (plates of collagen fibrils), superimposed one on another. They are each about 1.5-2.5 micrometres in thickness. These fibrils run at different angles between the limbi. Fibres of the layers frequently interweave, the anterior lamell��ｽｦ interweaving more than posterior lamell��ｽｦ. The fibres of each lamella are parallel with one another, but at right angles to those of adjacent lamell��ｽｦ. The lamell��ｽｦ are produced by keratocytes (corneal corpuscles), which occupy about 10% of the substantia propria. These lamell��ｽｦ are made up of bundles of modified connective tissue, the fibres of which are directly continuous with those of the sclera. More collagen fibres run in a temporal-nasal direction than run in the superior-inferior direction. This is often ignored by corneal transplant surgeons, leading to poor corneal mechanical strength in corneal transplant patients. [WP,unvetted]." [Wikipedia:Corneal_stroma] | ||
| Xrefs: |
| ||
| Synonyms: |
"cornea stroma" EXACT [] "corneal stroma" EXACT [] "stroma of cornea" EXACT [] "substantia propria" RELATED [] | ||
| Comments: | This class was created automatically from a combination of ontologies | ||
| Alt_id: | UBERON:FMA_58306-MA_0001245 | ||
| Subset: |
uberon_slim vertebrate_core |
200px-Gray871.png]
Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data
Parents
| is_a: | UBERON:0003891(stroma),UBERON:0010313(neural crest-derived structure) |
|---|---|
| develops_from: | UBERON:0007213(mesenchyme derived from head neural crest) |
| part_of: | UBERON:0000964(cornea) |
Children
| part of: | CL:0002363 (keratocyte) |
|---|
Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology
Human (Homo sapiens)
- 11527-119I6 (Keratocytes, donor1)
- 11607-120I5 (Keratocytes, donor2)
- 11688-122I5 (Keratocytes, donor3)
Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0001777 (substantia propria of cornea), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data
| P-value | FFCP | Short description |
|---|---|---|
| 1.55e-98 | FFCP PHASE1:Hg19::chr7:150910973..150910976,-#_30f7b30922b07b3050d9176a9b5d85ea | p@chr7:150910973..150910976, - |
| 1.55e-98 | FFCP PHASE2:Hg19::chr3:52362029..52362031,+#_30f7b30922b07b3050d9176a9b5d85ea | p@chr3:52362029..52362031, + |
| 1.55e-98 | FFCP PHASE1:Hg19::chr3:52362029..52362031,+#_30f7b30922b07b3050d9176a9b5d85ea | p@chr3:52362029..52362031, + |
| 1.55e-98 | FFCP PHASE2:Hg19::chr7:150910973..150910976,-#_30f7b30922b07b3050d9176a9b5d85ea | p@chr7:150910973..150910976, - |
| 4.52e-50 | FFCP PHASE1:Hg19::chr6:113369869..113369877,+#_1bbd5c58093665e40218473c455f369d | p@chr6:113369869..113369877, + |
| 4.52e-50 | FFCP PHASE2:Hg19::chr15:49255230..49255248,-#_1bbd5c58093665e40218473c455f369d | p16@SHC4 |
| 4.52e-50 | FFCP PHASE2:Hg19::chr8:22932230..22932233,-#_1bbd5c58093665e40218473c455f369d | p5@ENST00000520840, p5@ENST00000523806 |
| 4.52e-50 | FFCP PHASE1:Hg19::chr8:22932230..22932233,-#_1bbd5c58093665e40218473c455f369d | p5@ENST00000520840, p5@ENST00000523806 |
| 4.52e-50 | FFCP PHASE1:Hg19::chr10:92617531..92617541,-#_1bbd5c58093665e40218473c455f369d | p8@HTR7 |
| 4.52e-50 | FFCP PHASE2:Hg19::chr6:113369869..113369877,+#_1bbd5c58093665e40218473c455f369d | p@chr6:113369869..113369877, + |
| 4.52e-50 | FFCP PHASE1:Hg19::chr15:49255230..49255248,-#_1bbd5c58093665e40218473c455f369d | p16@SHC4 |
| 4.52e-50 | FFCP PHASE2:Hg19::chr10:92617531..92617541,-#_1bbd5c58093665e40218473c455f369d | p8@HTR7 |
| 5.04e-34 | FFCP PHASE2:Hg19::chr21:47410794..47410799,+#_aba62d1b9ef569dcb04ef444be94a928 | p@chr21:47410794..47410799, + |
| 5.04e-34 | FFCP PHASE1:Hg19::chr21:47410794..47410799,+#_aba62d1b9ef569dcb04ef444be94a928 | p@chr21:47410794..47410799, + |
| 5.04e-34 | FFCP PHASE2:Hg19::chr1:44820685..44820695,-#_aba62d1b9ef569dcb04ef444be94a928 | p10@ERI3 |
| 5.04e-34 | FFCP PHASE1:Hg19::chr1:44820685..44820695,-#_aba62d1b9ef569dcb04ef444be94a928 | p10@ERI3 |
| 5.04e-34 | FFCP PHASE2:Hg19::chr6:151770193..151770196,-#_aba62d1b9ef569dcb04ef444be94a928 | p@chr6:151770193..151770196, - |
| 5.04e-34 | FFCP PHASE1:Hg19::chr6:151770193..151770196,-#_aba62d1b9ef569dcb04ef444be94a928 | p@chr6:151770193..151770196, - |
| 7.05e-34 | FFCP PHASE1:Hg19::chr15:101459410..101459421,-#_b5550821167fa927230b8bf46d90a4a9 | p2@ENST00000560068 |
| 7.05e-34 | FFCP PHASE1:Hg19::chr10:43133595..43133606,-#_b5550821167fa927230b8bf46d90a4a9 | p@chr10:43133595..43133606, - |
| 7.05e-34 | FFCP PHASE1:Hg19::chr5:79375654..79375674,+#_b5550821167fa927230b8bf46d90a4a9 | p@chr5:79375654..79375674, + |
| 7.05e-34 | FFCP PHASE1:Hg19::chr10:74020629..74020634,-#_b5550821167fa927230b8bf46d90a4a9 | p@chr10:74020629..74020634, - |
| 7.05e-34 | FFCP PHASE2:Hg19::chr15:101459410..101459421,-#_b5550821167fa927230b8bf46d90a4a9 | p2@ENST00000560068 |
| 7.05e-34 | FFCP PHASE2:Hg19::chr11:65265332..65265342,+#_b5550821167fa927230b8bf46d90a4a9 | p19@MALAT1 |
| 7.05e-34 | FFCP PHASE2:Hg19::chr2:25383828..25383855,-#_b5550821167fa927230b8bf46d90a4a9 | p4@POMC |
| 7.05e-34 | FFCP PHASE2:Hg19::chr1:9970194..9970195,-#_b5550821167fa927230b8bf46d90a4a9 | p14@CTNNBIP1 |
| 7.05e-34 | FFCP PHASE2:Hg19::chr10:43133595..43133606,-#_b5550821167fa927230b8bf46d90a4a9 | p@chr10:43133595..43133606, - |
| 7.05e-34 | FFCP PHASE1:Hg19::chr2:25383828..25383855,-#_b5550821167fa927230b8bf46d90a4a9 | p4@POMC |
| 7.05e-34 | FFCP PHASE2:Hg19::chr10:74020629..74020634,-#_b5550821167fa927230b8bf46d90a4a9 | p@chr10:74020629..74020634, - |
| 7.05e-34 | FFCP PHASE1:Hg19::chr1:9970194..9970195,-#_b5550821167fa927230b8bf46d90a4a9 | p14@CTNNBIP1 |
| 7.05e-34 | FFCP PHASE1:Hg19::chr11:65265332..65265342,+#_b5550821167fa927230b8bf46d90a4a9 | p19@MALAT1 |
| 7.05e-34 | FFCP PHASE2:Hg19::chr5:79375654..79375674,+#_b5550821167fa927230b8bf46d90a4a9 | p@chr5:79375654..79375674, + |
| 6.41e-31 | FFCP PHASE2:Hg19::chr4:111536534..111536575,-#_8b16d2da7d04c381833ab6d4a3d4191f | p1@ENST00000503456 |
| 6.41e-31 | FFCP PHASE1:Hg19::chr4:111536534..111536575,-#_8b16d2da7d04c381833ab6d4a3d4191f | p1@ENST00000503456 |
| 4.55e-29 | FFCP PHASE2:Hg19::chrX:19688475..19688492,-#_72b8f44f4f9c9883b82a3be157be9b49 | p26@SH3KBP1 |
| 4.55e-29 | FFCP PHASE1:Hg19::chrX:19688475..19688492,-#_72b8f44f4f9c9883b82a3be157be9b49 | p26@SH3KBP1 |
| 9.18e-26 | FFCP PHASE1:Hg19::chr1:93646042..93646043,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p7@TMED5 |
| 9.18e-26 | FFCP PHASE2:Hg19::chr7:6049190..6049209,+#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr7:6049190..6049209, + |
| 9.18e-26 | FFCP PHASE2:Hg19::chr4:120546882..120546885,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr4:120546882..120546885, - |
| 9.18e-26 | FFCP PHASE2:Hg19::chr1:179335101..179335112,+#_53de05d9a3c9c8f56c37ffadd63fef2c | p6@AXDND1 |
| 9.18e-26 | FFCP PHASE1:Hg19::chr4:73434498..73434509,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p6@ADAMTS3 |
| 9.18e-26 | FFCP PHASE1:Hg19::chr20:60758060..60758074,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr20:60758060..60758074, - |
| 9.18e-26 | FFCP PHASE2:Hg19::chr3:9956047..9956079,+#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr3:9956047..9956079, + |
| 9.18e-26 | FFCP PHASE1:Hg19::chr15:90344775..90344794,+#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr15:90344775..90344794, + |
| 9.18e-26 | FFCP PHASE2:Hg19::chr1:36024782..36024791,+#_53de05d9a3c9c8f56c37ffadd63fef2c | p4@AB383919 |
| 9.18e-26 | FFCP PHASE1:Hg19::chr7:6049190..6049209,+#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr7:6049190..6049209, + |
| 9.18e-26 | FFCP PHASE1:Hg19::chr4:120546882..120546885,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr4:120546882..120546885, - |
| 9.18e-26 | FFCP PHASE1:Hg19::chr3:9956047..9956079,+#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr3:9956047..9956079, + |
| 9.18e-26 | FFCP PHASE1:Hg19::chr1:179335101..179335112,+#_53de05d9a3c9c8f56c37ffadd63fef2c | p6@AXDND1 |
| 9.18e-26 | FFCP PHASE1:Hg19::chr1:151171326..151171337,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr1:151171326..151171337, - |
| 9.18e-26 | FFCP PHASE2:Hg19::chr21:47681190..47681194,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr21:47681190..47681194, - |
| 9.18e-26 | FFCP PHASE2:Hg19::chr16:10590513..10590515,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr16:10590513..10590515, - |
| 9.18e-26 | FFCP PHASE1:Hg19::chr1:36024782..36024791,+#_53de05d9a3c9c8f56c37ffadd63fef2c | p4@AB383919 |
| 9.18e-26 | FFCP PHASE1:Hg19::chr12:53693440..53693450,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p2@CU687581 |
| 9.18e-26 | FFCP PHASE2:Hg19::chr4:57522753..57522760,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p18@HOPX |
| 9.18e-26 | FFCP PHASE1:Hg19::chr21:47681190..47681194,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr21:47681190..47681194, - |
| 9.18e-26 | FFCP PHASE2:Hg19::chr15:90344775..90344794,+#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr15:90344775..90344794, + |
| 9.18e-26 | FFCP PHASE2:Hg19::chr7:100806199..100806216,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr7:100806199..100806216, - |
| 9.18e-26 | FFCP PHASE1:Hg19::chr10:86153606..86153623,+#_53de05d9a3c9c8f56c37ffadd63fef2c | p9@FAM190B |
| 9.18e-26 | FFCP PHASE2:Hg19::chr2:219540880..219540912,+#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr2:219540880..219540912, + |
| 9.18e-26 | FFCP PHASE1:Hg19::chr17:30185971..30185986,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p7@C17orf79 |
| 9.18e-26 | FFCP PHASE1:Hg19::chr7:100806199..100806216,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr7:100806199..100806216, - |
| 9.18e-26 | FFCP PHASE1:Hg19::chr11:34073641..34073656,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr11:34073641..34073656, - |
| 9.18e-26 | FFCP PHASE2:Hg19::chr21:47397571..47397582,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr21:47397571..47397582, - |
| 9.18e-26 | FFCP PHASE1:Hg19::chr4:57522753..57522760,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p18@HOPX |
| 9.18e-26 | FFCP PHASE1:Hg19::chr2:219540880..219540912,+#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr2:219540880..219540912, + |
| 9.18e-26 | FFCP PHASE1:Hg19::chr21:47397571..47397582,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr21:47397571..47397582, - |
| 9.18e-26 | FFCP PHASE2:Hg19::chr4:73434498..73434509,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p6@ADAMTS3 |
| 9.18e-26 | FFCP PHASE2:Hg19::chr17:30185971..30185986,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p7@C17orf79 |
| 9.18e-26 | FFCP PHASE2:Hg19::chr12:53693440..53693450,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p2@CU687581 |
| 9.18e-26 | FFCP PHASE2:Hg19::chr10:86153606..86153623,+#_53de05d9a3c9c8f56c37ffadd63fef2c | p9@FAM190B |
| 9.18e-26 | FFCP PHASE2:Hg19::chr1:93646042..93646043,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p7@TMED5 |
| 9.18e-26 | FFCP PHASE2:Hg19::chr11:34073641..34073656,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr11:34073641..34073656, - |
| 9.18e-26 | FFCP PHASE2:Hg19::chr1:151171326..151171337,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr1:151171326..151171337, - |
| 9.18e-26 | FFCP PHASE2:Hg19::chr20:60758060..60758074,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr20:60758060..60758074, - |
| 9.18e-26 | FFCP PHASE1:Hg19::chr16:10590513..10590515,-#_53de05d9a3c9c8f56c37ffadd63fef2c | p@chr16:10590513..10590515, - |
| 6.02e-24 | FFCP PHASE1:Hg19::chr1:145589059..145589070,-#_449cd59297011b978ac9c00cb5d621f6 | p3@NUDT17 |
| 6.02e-24 | FFCP PHASE2:Hg19::chr1:145589059..145589070,-#_449cd59297011b978ac9c00cb5d621f6 | p3@NUDT17 |
| 3.81e-21 | FFCP PHASE1:Hg19::chr17:19648416..19648426,-#_c643b3bbedb7ca9a2b69caa0557e7e3e | p13@ALDH3A1 |
| 3.81e-21 | FFCP PHASE2:Hg19::chr17:19648416..19648426,-#_c643b3bbedb7ca9a2b69caa0557e7e3e | p13@ALDH3A1 |
| 4.66e-21 | FFCP PHASE1:Hg19::chr6:41562324..41562340,+#_a132959ce27ce8b4e0be0ff5504fbf07 | p16@FOXP4 |
| 4.66e-21 | FFCP PHASE2:Hg19::chr4:52917466..52917498,-#_a132959ce27ce8b4e0be0ff5504fbf07 | p@chr4:52917466..52917498, - |
| 4.66e-21 | FFCP PHASE1:Hg19::chr4:52917466..52917498,-#_a132959ce27ce8b4e0be0ff5504fbf07 | p@chr4:52917466..52917498, - |
| 4.66e-21 | FFCP PHASE2:Hg19::chr6:41562324..41562340,+#_a132959ce27ce8b4e0be0ff5504fbf07 | p16@FOXP4 |
| 5.7e-21 | FFCP PHASE1:Hg19::chr5:142254452..142254462,+#_6827444bb6735ba3e4bf22b13bf4646b | p29@ARHGAP26 |
| 5.7e-21 | FFCP PHASE2:Hg19::chr7:73118172..73118185,-#_6827444bb6735ba3e4bf22b13bf4646b | p3@STX1A |
| 5.7e-21 | FFCP PHASE1:Hg19::chr7:73118172..73118185,-#_6827444bb6735ba3e4bf22b13bf4646b | p3@STX1A |
| 5.7e-21 | FFCP PHASE1:Hg19::chr12:58141331..58141342,+#_6827444bb6735ba3e4bf22b13bf4646b | p@chr12:58141331..58141342, + |
| 5.7e-21 | FFCP PHASE2:Hg19::chr8:27686258..27686262,-#_6827444bb6735ba3e4bf22b13bf4646b | p@chr8:27686258..27686262, - |
| 5.7e-21 | FFCP PHASE1:Hg19::chr8:27686258..27686262,-#_6827444bb6735ba3e4bf22b13bf4646b | p@chr8:27686258..27686262, - |
| 5.7e-21 | FFCP PHASE2:Hg19::chr19:48244695..48244702,+#_6827444bb6735ba3e4bf22b13bf4646b | p14@EHD2 |
| 5.7e-21 | FFCP PHASE2:Hg19::chr12:58141331..58141342,+#_6827444bb6735ba3e4bf22b13bf4646b | p@chr12:58141331..58141342, + |
| 5.7e-21 | FFCP PHASE1:Hg19::chr19:48244695..48244702,+#_6827444bb6735ba3e4bf22b13bf4646b | p14@EHD2 |
| 5.7e-21 | FFCP PHASE2:Hg19::chr5:142254452..142254462,+#_6827444bb6735ba3e4bf22b13bf4646b | p29@ARHGAP26 |
| 6.96e-21 | FFCP PHASE1:Hg19::chr5:6766044..6766055,+#_3b19ef7bdbfd9a808b1be5d581addf21 | p2@ENST00000506093 |
| 6.96e-21 | FFCP PHASE1:Hg19::chr2:37898966..37898999,+#_3b19ef7bdbfd9a808b1be5d581addf21 | p@chr2:37898966..37898999, + |
| 6.96e-21 | FFCP PHASE1:Hg19::chr17:53803029..53803034,-#_3b19ef7bdbfd9a808b1be5d581addf21 | p@chr17:53803029..53803034, - |
| 6.96e-21 | FFCP PHASE2:Hg19::chr6:30585100..30585105,-#_3b19ef7bdbfd9a808b1be5d581addf21 | p19@PPP1R10 |
| 6.96e-21 | FFCP PHASE2:Hg19::chr17:71283257..71283270,-#_3b19ef7bdbfd9a808b1be5d581addf21 | p@chr17:71283257..71283270, - |
| 6.96e-21 | FFCP PHASE2:Hg19::chr9:140348438..140348460,-#_3b19ef7bdbfd9a808b1be5d581addf21 | p@chr9:140348438..140348460, - |
Property "Property value" (as page type) with input value "UBPROP:0000001 "Portion of tissue that is located basal to Bowman's layer and distal to Descemet's membrane and is comprised largely of connective tissue.[TAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.
