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UBERON:0001954

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Name:Ammon's horn
Namespace:FANTOM
Definition:"A paired structure, with mirror-image halves in the left and right sides of the brain. The hippocampus is closely associated with the cerebral cortex, and in primates is located in the medial temporal lobe, underneath the cortical surface. It is shaped like a curved tube[WP]." [Wikipedia:Hippocampus]
Xrefs:
links:

ABA:CA
BM:Tel-CAM
BTO:0003705
EFO:0000530
EHDAA2:0004443
EMAPA:19039
EMAPA:19148
EV:0100180
FMA:62493
GAID:623

[1]
Synonyms: "ammon gyrus" EXACT [GO:0021541]
"ammon horn" EXACT [NIF_GrossAnatomy:birnlex_721]
"Ammon's horn" EXACT [GO:0021541]
"cornu ammonis" RELATED [GO:0021541]
"hippocampus" RELATED [MA:0000191]
"hippocampus major" EXACT []
"hippocampus proper" EXACT []
"hippocampus proprius" EXACT [FMA:62493, FMA:TA]
Comments:WP: Non-mammalian species do not have a brain structure that looks like the mammalian hippocampus, but they have one that is considered homologous to it. The hippocampus, as pointed out above, is essentially the medial edge of the cortex. Only mammals have a fully developed cortex, but the structure it evolved from, called the pallium, is present in all vertebrates, even the most primitive ones such as the lamprey or hagfish.[82] The pallium is usually divided into three zones: medial, lateral, and dorsal. The medial pallium forms the precursor of the hippocampus. It does not resemble the hippocampus visually, because the layers are not warped into an S shape or enwrapped by the dentate gyrus, but the homology is indicated by strong chemical and functional affinities. There is now evidence that these hippocampal-like structures are involved in spatial cognition in birds, reptiles, and fish. In birds, the correspondence is sufficiently well established that most anatomists refer to the medial pallial zone as the "avian hippocampus". The story for fish is more complex. In teleost fish (which make up the great majority of existing species), the forebrain is distorted in comparison to other types of vertebrates: most neuroanatomists believe that the teleost forebrain is essentially everted, like a sock turned inside-out, so that structures that lie in the interior, next to the ventricles, for most vertebrates, are found on the outside in teleost fish, and vice versa.[86] One of the consequences of this is that the medial pallium ("hippocampal" zone) of a typical vertebrate is thought to correspond to the lateral pallium of a typical fish. Several types of fish (particularly goldfish) have been shown experimentally to have strong spatial memory abilities, even forming "cognitive maps" of the areas they inhabit.[80] There is evidence that damage to the lateral pallium impairs spatial memory.
Alt_id: UBERON:0003940
UBERON:0004165
UBERON:FMA_62493-MA_0000191-MIAA_0000114
Subset: uberon_slim

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:UBERON:0002791(regional part of telencephalon)
part_of:UBERON:0000349(limbic system),UBERON:0002421(hippocampal formation),UBERON:0002600(limbic lobe)



Children

is a:FF:10363-105F3 (hippocampus, newborn, donor10223),FF:13-16E8 (hippocampus, adult)
derives from:FF:0010153 (hippocampus - adult sample),FF:0011391 (mouse hippocampus- neonate N00 sample)
part of:FF:0000197 (mouse astrocyte of hippocampus sample),CL:0002604 (astrocyte of the hippocampus),CL:0002608 (hippocampal neuron),FF:0010153 (hippocampus - adult sample),CL:1001580 (hippocampus glial cell)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology

Human (Homo sapiens)

... further results Mouse (Mus musculus)

... further results


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0001954 (Ammon's horn), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
5.68e-99FFCP PHASE2:Hg19::chr2:149881275..149881284,+#_4ee7a82146d3b0b0cde75c44aef3e8aep@chr2:149881275..149881284, +
5.68e-99FFCP PHASE2:Hg19::chrX:148561320..148561329,-#_4ee7a82146d3b0b0cde75c44aef3e8aep@chrX:148561320..148561329, -
5.68e-99FFCP PHASE1:Hg19::chr2:149881275..149881284,+#_4ee7a82146d3b0b0cde75c44aef3e8aep@chr2:149881275..149881284, +
5.68e-99FFCP PHASE1:Hg19::chrX:148561320..148561329,-#_4ee7a82146d3b0b0cde75c44aef3e8aep@chrX:148561320..148561329, -
1.55e-98FFCP PHASE2:Hg19::chr6:132937900..132937907,-#_11688ec4cf6e7d67f5e340ad91f1184ap@chr6:132937900..132937907, -
1.55e-98FFCP PHASE2:Hg19::chrX:110464144..110464149,+#_11688ec4cf6e7d67f5e340ad91f1184ap@chrX:110464144..110464149, +
1.55e-98FFCP PHASE1:Hg19::chr2:187628574..187628585,+#_11688ec4cf6e7d67f5e340ad91f1184ap@chr2:187628574..187628585, +
1.55e-98FFCP PHASE1:Hg19::chrX:110464144..110464149,+#_11688ec4cf6e7d67f5e340ad91f1184ap@chrX:110464144..110464149, +
1.55e-98FFCP PHASE2:Hg19::chr2:187628574..187628585,+#_11688ec4cf6e7d67f5e340ad91f1184ap@chr2:187628574..187628585, +
1.55e-98FFCP PHASE1:Hg19::chr6:132937900..132937907,-#_11688ec4cf6e7d67f5e340ad91f1184ap@chr6:132937900..132937907, -
4.22e-98FFCP PHASE2:Hg19::chr5:119669127..119669137,-#_172d5d52d3c336c8079c7e446836e880p4@ENST00000514240
4.22e-98FFCP PHASE1:Hg19::chr3:172166557..172166598,+#_172d5d52d3c336c8079c7e446836e880p@chr3:172166557..172166598, +
4.22e-98FFCP PHASE2:Hg19::chr3:172166557..172166598,+#_172d5d52d3c336c8079c7e446836e880p@chr3:172166557..172166598, +
4.22e-98FFCP PHASE1:Hg19::chr3:71777824..71777833,-#_172d5d52d3c336c8079c7e446836e880p28@EIF4E3
4.22e-98FFCP PHASE1:Hg19::chr11:79784329..79784335,-#_172d5d52d3c336c8079c7e446836e880p@chr11:79784329..79784335, -
4.22e-98FFCP PHASE2:Hg19::chr3:71777824..71777833,-#_172d5d52d3c336c8079c7e446836e880p28@EIF4E3
4.22e-98FFCP PHASE2:Hg19::chr11:79784329..79784335,-#_172d5d52d3c336c8079c7e446836e880p@chr11:79784329..79784335, -
4.22e-98FFCP PHASE1:Hg19::chr5:119669127..119669137,-#_172d5d52d3c336c8079c7e446836e880p4@ENST00000514240
7.79e-79FFCP PHASE2:Hg19::chr18:24435190..24435201,-#_88a1eaa31d628d6280ba56b0acd9e4ebp@chr18:24435190..24435201, -
7.79e-79FFCP PHASE1:Hg19::chr18:24435190..24435201,-#_88a1eaa31d628d6280ba56b0acd9e4ebp@chr18:24435190..24435201, -
7.41e-67FFCP PHASE1:Hg19::chr10:125454018..125454027,+#_0ac29e009f0705bba7501e8d106f933ep@chr10:125454018..125454027, +
7.41e-67FFCP PHASE2:Hg19::chr10:125454018..125454027,+#_0ac29e009f0705bba7501e8d106f933ep@chr10:125454018..125454027, +
1.04e-66FFCP PHASE2:Hg19::chr3:12225071..12225084,+#_38b025aebb4a1a1057fd175d91996f62p15@SYN2
1.04e-66FFCP PHASE1:Hg19::chr3:12225071..12225084,+#_38b025aebb4a1a1057fd175d91996f62p15@SYN2
7.73e-66FFCP PHASE2:Hg19::chrX:72432586..72432597,-#_334c30cea869a37ae6edcc771df29a53p@chrX:72432586..72432597, -
7.73e-66FFCP PHASE1:Hg19::chrX:72432586..72432597,-#_334c30cea869a37ae6edcc771df29a53p@chrX:72432586..72432597, -
2.02e-57FFCP PHASE1:Hg19::chr7:130745294..130745303,-#_8e30073fb8252c3c4ee8b260ab1d53acp@chr7:130745294..130745303, -
2.02e-57FFCP PHASE2:Hg19::chr7:130745294..130745303,-#_8e30073fb8252c3c4ee8b260ab1d53acp@chr7:130745294..130745303, -
2.02e-57FFCP PHASE2:Hg19::chrX:13789306..13789315,-#_8e30073fb8252c3c4ee8b260ab1d53acp@chrX:13789306..13789315, -
2.02e-57FFCP PHASE1:Hg19::chrX:13789306..13789315,-#_8e30073fb8252c3c4ee8b260ab1d53acp@chrX:13789306..13789315, -
2.69e-57FFCP PHASE1:Hg19::chr19:49932793..49932820,-#_daf1770a156fae7f3d1572d6c1f3dd91p@chr19:49932793..49932820, -
2.69e-57FFCP PHASE2:Hg19::chr19:49932793..49932820,-#_daf1770a156fae7f3d1572d6c1f3dd91p@chr19:49932793..49932820, -
3.58e-57FFCP PHASE2:Hg19::chr5:111964224..111964247,+#_ef0685727cd6a9773b7c07912ab0a3a6p1@ENST00000507565
3.58e-57FFCP PHASE1:Hg19::chr2:79601075..79601083,+#_ef0685727cd6a9773b7c07912ab0a3a6p@chr2:79601075..79601083, +
3.58e-57FFCP PHASE2:Hg19::chr2:79601075..79601083,+#_ef0685727cd6a9773b7c07912ab0a3a6p@chr2:79601075..79601083, +
3.58e-57FFCP PHASE1:Hg19::chr5:111964224..111964247,+#_ef0685727cd6a9773b7c07912ab0a3a6p1@ENST00000507565
4.77e-57FFCP PHASE2:Hg19::chr7:22158177..22158186,-#_9d0ff3422b20a5d7f808caefe4682440p@chr7:22158177..22158186, -
4.77e-57FFCP PHASE1:Hg19::chr7:22158177..22158186,-#_9d0ff3422b20a5d7f808caefe4682440p@chr7:22158177..22158186, -
6.36e-57FFCP PHASE2:Hg19::chr8:42981738..42981749,+#_45c88362cf1fcf3a5ed13a011c7e1855p4@AK056481
6.36e-57FFCP PHASE1:Hg19::chr8:42981738..42981749,+#_45c88362cf1fcf3a5ed13a011c7e1855p4@AK056481
8.82e-51FFCP PHASE1:Hg19::chr5:82155710..82155724,-#_3d8aeaab617bd303db0fdc4ddbae3d38p@chr5:82155710..82155724, -
8.82e-51FFCP PHASE2:Hg19::chr5:82155710..82155724,-#_3d8aeaab617bd303db0fdc4ddbae3d38p@chr5:82155710..82155724, -
1.14e-50FFCP PHASE1:Hg19::chr17:27901500..27901511,-#_40d7dded7139b37ed2340e60959033f0p25@GIT1
1.14e-50FFCP PHASE2:Hg19::chr17:27901500..27901511,-#_40d7dded7139b37ed2340e60959033f0p25@GIT1
1.14e-50FFCP PHASE1:Hg19::chr15:43814895..43814906,+#_40d7dded7139b37ed2340e60959033f0p35@MAP1A
1.14e-50FFCP PHASE2:Hg19::chr15:43814895..43814906,+#_40d7dded7139b37ed2340e60959033f0p35@MAP1A
2.42e-50FFCP PHASE1:Hg19::chr13:101712292..101712306,-#_bb8a6cd7bc8b157e38955982265f6991p@chr13:101712292..101712306, -
2.42e-50FFCP PHASE2:Hg19::chr13:101712292..101712306,-#_bb8a6cd7bc8b157e38955982265f6991p@chr13:101712292..101712306, -
2.74e-50FFCP PHASE2:Hg19::chr3:131756632..131756637,-#_8598e8f6ab16fb5667f409c765e44167p11@CPNE4
2.74e-50FFCP PHASE1:Hg19::chr3:131756644..131756651,-#_8598e8f6ab16fb5667f409c765e44167p13@CPNE4
2.74e-50FFCP PHASE2:Hg19::chr3:131756644..131756651,-#_8598e8f6ab16fb5667f409c765e44167p13@CPNE4
2.74e-50FFCP PHASE1:Hg19::chr16:7240507..7240509,+#_8598e8f6ab16fb5667f409c765e44167p@chr16:7240507..7240509, +
2.74e-50FFCP PHASE2:Hg19::chr19:49932741..49932746,-#_8598e8f6ab16fb5667f409c765e44167p@chr19:49932741..49932746, -
2.74e-50FFCP PHASE2:Hg19::chr16:7240507..7240509,+#_8598e8f6ab16fb5667f409c765e44167p@chr16:7240507..7240509, +
2.74e-50FFCP PHASE1:Hg19::chr19:49932741..49932746,-#_8598e8f6ab16fb5667f409c765e44167p@chr19:49932741..49932746, -
2.74e-50FFCP PHASE1:Hg19::chr3:131756632..131756637,-#_8598e8f6ab16fb5667f409c765e44167p11@CPNE4
3.11e-50FFCP PHASE2:Hg19::chr11:123502588..123502633,-#_bbc09736f53d6d9abbabb75d18714a19p16@SCN3B
3.11e-50FFCP PHASE1:Hg19::chr11:123502588..123502633,-#_bbc09736f53d6d9abbabb75d18714a19p16@SCN3B
4.0e-50FFCP PHASE1:Hg19::chr3:58552313..58552322,-#_72e5bd4a90771a3e0432aaa25fd931ccp@chr3:58552313..58552322, -
4.0e-50FFCP PHASE2:Hg19::chr3:58552313..58552322,-#_72e5bd4a90771a3e0432aaa25fd931ccp@chr3:58552313..58552322, -
4.52e-50FFCP PHASE2:Hg19::chr7:98460933..98460941,-#_7aada647b9334679f28350fbdbba2aeap19@TMEM130
4.52e-50FFCP PHASE1:Hg19::chr8:81570615..81570619,-#_7aada647b9334679f28350fbdbba2aeap@chr8:81570615..81570619, -
4.52e-50FFCP PHASE1:Hg19::chr21:27651095..27651104,+#_7aada647b9334679f28350fbdbba2aeap@chr21:27651095..27651104, +
4.52e-50FFCP PHASE2:Hg19::chr20:44330800..44330802,-#_7aada647b9334679f28350fbdbba2aeap@chr20:44330800..44330802, -
4.52e-50FFCP PHASE2:Hg19::chr8:26365361..26365372,-#_7aada647b9334679f28350fbdbba2aeap5@PNMA2
4.52e-50FFCP PHASE2:Hg19::chr21:27650939..27650945,-#_7aada647b9334679f28350fbdbba2aeap@chr21:27650939..27650945, -
4.52e-50FFCP PHASE2:Hg19::chr19:4772190..4772197,+#_7aada647b9334679f28350fbdbba2aeap@chr19:4772190..4772197, +
4.52e-50FFCP PHASE2:Hg19::chr1:99772065..99772074,+#_7aada647b9334679f28350fbdbba2aeap13@LPPR4
4.52e-50FFCP PHASE1:Hg19::chr8:26365361..26365372,-#_7aada647b9334679f28350fbdbba2aeap5@PNMA2
4.52e-50FFCP PHASE2:Hg19::chr18:24433388..24433397,-#_7aada647b9334679f28350fbdbba2aeap20@AQP4
4.52e-50FFCP PHASE1:Hg19::chr20:44330800..44330802,-#_7aada647b9334679f28350fbdbba2aeap@chr20:44330800..44330802, -
4.52e-50FFCP PHASE1:Hg19::chr19:4772190..4772197,+#_7aada647b9334679f28350fbdbba2aeap@chr19:4772190..4772197, +
4.52e-50FFCP PHASE2:Hg19::chr21:27651095..27651104,+#_7aada647b9334679f28350fbdbba2aeap@chr21:27651095..27651104, +
4.52e-50FFCP PHASE1:Hg19::chr21:27650939..27650945,-#_7aada647b9334679f28350fbdbba2aeap@chr21:27650939..27650945, -
4.52e-50FFCP PHASE1:Hg19::chr18:24433388..24433397,-#_7aada647b9334679f28350fbdbba2aeap20@AQP4
4.52e-50FFCP PHASE2:Hg19::chr8:81570615..81570619,-#_7aada647b9334679f28350fbdbba2aeap@chr8:81570615..81570619, -
4.52e-50FFCP PHASE1:Hg19::chr1:99772065..99772074,+#_7aada647b9334679f28350fbdbba2aeap13@LPPR4
4.52e-50FFCP PHASE2:Hg19::chrX:152095682..152095708,-#_7aada647b9334679f28350fbdbba2aeap@chrX:152095682..152095708, -
4.52e-50FFCP PHASE1:Hg19::chr7:98460933..98460941,-#_7aada647b9334679f28350fbdbba2aeap19@TMEM130
4.52e-50FFCP PHASE1:Hg19::chrX:152095682..152095708,-#_7aada647b9334679f28350fbdbba2aeap@chrX:152095682..152095708, -
5.15e-50FFCP PHASE1:Hg19::chr14:24037817..24037858,-#_6530bc1c3689a5c5d0957f2c8d83f508p@chr14:24037817..24037858, -
5.15e-50FFCP PHASE2:Hg19::chr14:24037817..24037858,-#_6530bc1c3689a5c5d0957f2c8d83f508p@chr14:24037817..24037858, -
6.61e-50FFCP PHASE1:Hg19::chr12:41234328..41234338,+#_6fe6e7359d84040ca54fbd91cd14c969p@chr12:41234328..41234338, +
6.61e-50FFCP PHASE2:Hg19::chr12:41234328..41234338,+#_6fe6e7359d84040ca54fbd91cd14c969p@chr12:41234328..41234338, +
3.19e-45FFCP PHASE1:Hg19::chr12:79843202..79843213,+#_39285d59ed12f226f8bb81a0f5d08a74p@chr12:79843202..79843213, +
3.19e-45FFCP PHASE2:Hg19::chr19:3294647..3294651,+#_39285d59ed12f226f8bb81a0f5d08a74p@chr19:3294647..3294651, +
3.19e-45FFCP PHASE2:Hg19::chr12:79843202..79843213,+#_39285d59ed12f226f8bb81a0f5d08a74p@chr12:79843202..79843213, +
3.19e-45FFCP PHASE1:Hg19::chr19:3294647..3294651,+#_39285d59ed12f226f8bb81a0f5d08a74p@chr19:3294647..3294651, +
6.26e-45FFCP PHASE1:Hg19::chr8:27316567..27316576,+#_840de89963c3a9877dd754108495f9f8p@chr8:27316567..27316576, +
6.26e-45FFCP PHASE2:Hg19::chr9:87426979..87426990,+#_840de89963c3a9877dd754108495f9f8p54@NTRK2
6.26e-45FFCP PHASE1:Hg19::chr9:87426979..87426990,+#_840de89963c3a9877dd754108495f9f8p54@NTRK2
6.26e-45FFCP PHASE1:Hg19::chr5:63258078..63258088,-#_840de89963c3a9877dd754108495f9f8p6@HTR1A
6.26e-45FFCP PHASE2:Hg19::chr5:63258078..63258088,-#_840de89963c3a9877dd754108495f9f8p6@HTR1A
6.26e-45FFCP PHASE2:Hg19::chr8:27316567..27316576,+#_840de89963c3a9877dd754108495f9f8p@chr8:27316567..27316576, +
7.83e-45FFCP PHASE1:Hg19::chr5:63258105..63258124,-#_dd0ba646118c816d9e26eb7531e47d11p2@HTR1A
7.83e-45FFCP PHASE2:Hg19::chr1:160112787..160112798,+#_dd0ba646118c816d9e26eb7531e47d11p12@ATP1A2
7.83e-45FFCP PHASE2:Hg19::chr5:63258105..63258124,-#_dd0ba646118c816d9e26eb7531e47d11p2@HTR1A
7.83e-45FFCP PHASE1:Hg19::chr2:101965038..101965076,-#_dd0ba646118c816d9e26eb7531e47d11p@chr2:101965038..101965076, -
7.83e-45FFCP PHASE1:Hg19::chr1:160112787..160112798,+#_dd0ba646118c816d9e26eb7531e47d11p12@ATP1A2
7.83e-45FFCP PHASE2:Hg19::chr2:101965038..101965076,-#_dd0ba646118c816d9e26eb7531e47d11p@chr2:101965038..101965076, -

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