UBERON:0002062
From FANTOM5_SSTAR
| Name: | endocardial cushion | |
|---|---|---|
| Namespace: | FANTOM | |
| Definition: | "The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves[GO]. Swellings of tissue present between the endocardial and myocardial cell layers that will give rise to the interstitial cells of the cardiac valves[ZFA]." [GO:0003197, Wikipedia:Endocardial_cushion, ZFIN:curator] | |
| Xrefs: |
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| Synonyms: |
"atrioventricular cushion" EXACT [Wikipedia:Endocardial_cushion] "cardiac cushion" EXACT [PMID:15797462] "endocardial cushion tissue" EXACT [EHDAA2:0000434] "endocardial cushions" RELATED PLURAL [] | |
| Comments: | GO graph seems to suggest this is an endothelium. WP: The endocardial cushions are thought to arise from a subset of endothelial cells that undergo epithelial to mesenchymal transformation, a process whereby these cells break cell-to-cell contacts and migrate into the cardiac jelly (towards to interior of the heart tube). Latest (2010-06-01) new def suggested for GO, added above. Note that EHDAA2 has a more detailed model which we may later adopt | |
| Alt_id: | UBERON:FMA_70302-MA_0000078-ZFA_0001317 | |
| Subset: |
uberon_slim vertebrate_core |
200px-Gray465.png]
Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data
Parents
| is_a: | UBERON:0005256(trunk mesenchyme),UBERON:0009751(cardiac mesenchyme),UBERON:0014387(mesenchyme derived from neural crest) |
|---|---|
| develops_from: | UBERON:0002342(neural crest) |
| part_of: | UBERON:0000922(embryo),UBERON:0000948(heart),UBERON:0002165(endocardium) |
Children
| develops from: | UBERON:0000946 (cardial valve),UBERON:0002133 (atrioventricular valve) |
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Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology
Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0002062 (endocardial cushion), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data
Property "Property value" (as page type) with input value "UBPROP:0000001 "Swellings of tissue present between the endocardial and myocardial cell layers that will give rise to the interstitial cells of the cardiac valves.[TAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process., Property "Property value" (as page type) with input value "UBPROP:0000002 "relationship loss: develops_from endocardial ring (TAO:0005072)[TAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.
