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UBERON:0005426

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Name:lens vesicle
Namespace:FANTOM
Definition:"Portion of tissue that gives rise to the lens." [https://sourceforge.net/tracker/?func
Xrefs:
links:

EHDAA2:0000983
EHDAA:4737
EMAPA:17163
SCTID:361510002
TAO:0002205
VHOG:0001163
ZFA:0001679

ZFIN:ZDB-ANAT-090226-2
Synonyms: "hollow lens vesicle" NARROW SENSU []
"solid lens vesicle" NARROW SENSU [ZFA:0001679]
Comments:Development notes: the lens of zebrafish (and other teleosts) forms from delamination of cells from the lens placode; thus, there is no formation of a hollow lens vesicle, in contrast to the situation in mammals and birds (Glass and Dahm, 2004) [PMID:16496288] The lens of the zebrafish forms by delamination of lens placodal cells and not through invagination. This results in a solid spherical mass as opposed to a hollow lens vesicle. Detachment of the solid lens vesicle of zebrafish at 24b26 hpf is accomplished in part by apoptosis, similar to mammals[ZFA]
Subset: vertebrate_core

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data


Parents

is_a:UBERON:0000479(tissue),UBERON:0004121(ectoderm-derived structure)
develops_from:UBERON:0003073(lens placode)



Children

develops from:UBERON:0000965 (lens of camera-type eye)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology




Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0005426 (lens vesicle), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data