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UBERON:0008193

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Name:pneumatized bone
Namespace:FANTOM
Definition:"a bone that is hollow or contains many air cells, such as the mastoid process of the temporal bone[TMD]. Skeletal pneumaticity is the presence of air spaces within bones. Skeletal pneumaticity exists only in synapsids and archosaurs. It is generally produced during development by excavation of bone by pneumatic diverticula (air sacs) from an air-filled space such as the lungs or nasal cavity. Pneumatization is highly variable between individuals, and bones not normally pneumatized can become pneumatized in pathological development. Pneumatization occurs in the skulls of mammals, crocodilians and birds among extant groups, as well as extinct archosaurs including the dinosaurs and pterosaurs. Pneumatic spaces include the paranasal sinuses and some of the mastoid cells[WP]." [http://www.medilexicon.com/medicaldictionary.php?t
Xrefs:
links:

FMA:7478
galen:PneumaticBone

SCTID:333008005
Synonyms: "hollow bone" RELATED []
"os pneumaticum" EXACT [FMA:7478]
"pneumatic bone" EXACT [FMA:7478]
Comments:editor note: subclasses of this should be checked for taxonomic consistency

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:UBERON:0008001(irregular bone)



Children

is a:UBERON:0001678 (temporal bone),UBERON:0002397 (maxilla)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology

Human (Homo sapiens)

  • 10813-111B3 (normal embryonic palatal mesenchymal cell line:HEPM)
  • 12157-128G6 (Sox2+ Supporting cells - organ of corti, pool1)
  • 12158-128G7 (Atoh+ Inner ear hair cells - organ of corti, pool1)
  • 12215-129E1 (Inner ear stem cells, 1st generation stem cells, pool1)
  • 12216-129E2 (Inner ear stem cells, 4th generation stem cells, pool1)
  • 12217-129E3 (Inner ear stem cells, differentiation, day03, pool1)
  • 12218-129E4 (Inner ear stem cells, differentiation, day10, pool1)

Mouse (Mus musculus)

  • 10813-111B3 (normal embryonic palatal mesenchymal cell line:HEPM)
  • 12157-128G6 (Sox2+ Supporting cells - organ of corti, pool1)
  • 12158-128G7 (Atoh+ Inner ear hair cells - organ of corti, pool1)
  • 12215-129E1 (Inner ear stem cells, 1st generation stem cells, pool1)
  • 12216-129E2 (Inner ear stem cells, 4th generation stem cells, pool1)
  • 12217-129E3 (Inner ear stem cells, differentiation, day03, pool1)
  • 12218-129E4 (Inner ear stem cells, differentiation, day10, pool1)


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0008193 (pneumatized bone), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
5.42e-195FFCP PHASE2:Hg19::chr17:54893192..54893195,-#_e9109d04bd7861cfd909269f68abe48cp14@C17orf67
5.42e-195FFCP PHASE1:Hg19::chr17:54893192..54893195,-#_e9109d04bd7861cfd909269f68abe48cp14@C17orf67
9.37e-99FFCP PHASE1:Hg19::chr8:57353655..57353662,-#_b16971364b464ba2168ebfb075271eafp@chr8:57353655..57353662, -
9.37e-99FFCP PHASE1:Hg19::chr17:54893213..54893220,-#_b16971364b464ba2168ebfb075271eafp12@C17orf67
9.37e-99FFCP PHASE2:Hg19::chr17:54893292..54893300,-#_b16971364b464ba2168ebfb075271eafp13@C17orf67
9.37e-99FFCP PHASE1:Hg19::chr17:54893269..54893278,-#_b16971364b464ba2168ebfb075271eafp11@C17orf67
9.37e-99FFCP PHASE1:Hg19::chr17:54893292..54893300,-#_b16971364b464ba2168ebfb075271eafp13@C17orf67
9.37e-99FFCP PHASE2:Hg19::chr17:54893213..54893220,-#_b16971364b464ba2168ebfb075271eafp12@C17orf67
9.37e-99FFCP PHASE2:Hg19::chr8:57353655..57353662,-#_b16971364b464ba2168ebfb075271eafp@chr8:57353655..57353662, -
9.37e-99FFCP PHASE2:Hg19::chr17:54893269..54893278,-#_b16971364b464ba2168ebfb075271eafp11@C17orf67
1.87e-86FFCP PHASE1:Mm9::chr19:22767090..22767099,+#_dce8c132c5fa3c8264cf9e4b787ecc16p18@Trpm3
1.87e-86FFCP PHASE2:Mm9::chr18:42158627..42158630,-#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr18:42158627..42158630, -
1.87e-86FFCP PHASE2:Mm9::chr13:78257491..78257498,+#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr13:78257491..78257498, +
1.87e-86FFCP PHASE1:Mm9::chr3:31585340..31585360,+#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr3:31585340..31585360, +
1.87e-86FFCP PHASE1:Mm9::chr2:136942131..136942142,-#_dce8c132c5fa3c8264cf9e4b787ecc16p6@Jag1
1.87e-86FFCP PHASE2:Mm9::chr2:128881546..128881553,-#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr2:128881546..128881553, -
1.87e-86FFCP PHASE1:Mm9::chr18:38104702..38104718,-#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr18:38104702..38104718, -
1.87e-86FFCP PHASE1:Mm9::chr11:94371127..94371139,-#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr11:94371127..94371139, -
1.87e-86FFCP PHASE2:Mm9::chr4:151505798..151505818,-#_dce8c132c5fa3c8264cf9e4b787ecc16p21@Espn
1.87e-86FFCP PHASE1:Mm9::chr4:115556989..115556997,+#_dce8c132c5fa3c8264cf9e4b787ecc16p1@Kncn
1.87e-86FFCP PHASE2:Mm9::chr1:93218694..93218705,+#_dce8c132c5fa3c8264cf9e4b787ecc16p1@Espnl
1.87e-86FFCP PHASE2:Mm9::chr14:47293487..47293493,-#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr14:47293487..47293493, -
1.87e-86FFCP PHASE1:Mm9::chr1:93218682..93218691,+#_dce8c132c5fa3c8264cf9e4b787ecc16p2@Espnl
1.87e-86FFCP PHASE1:Mm9::chr2:9811162..9811171,-#_dce8c132c5fa3c8264cf9e4b787ecc16p2@9230102O04Rik
1.87e-86FFCP PHASE2:Mm9::chr3:154693281..154693317,-#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr3:154693281..154693317, -
1.87e-86FFCP PHASE2:Mm9::chr9:42208142..42208157,-#_dce8c132c5fa3c8264cf9e4b787ecc16p10@Tecta
1.87e-86FFCP PHASE1:Mm9::chr8:13414289..13414295,+#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr8:13414289..13414295, +
1.87e-86FFCP PHASE1:Mm9::chr15:65641741..65641748,+#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr15:65641741..65641748, +
1.87e-86FFCP PHASE1:Mm9::chr13:78257491..78257498,+#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr13:78257491..78257498, +
1.87e-86FFCP PHASE2:Mm9::chr2:152453066..152453075,-#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr2:152453066..152453075, -
1.87e-86FFCP PHASE2:Mm9::chr12:13508046..13508055,+#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr12:13508046..13508055, +
1.87e-86FFCP PHASE2:Mm9::chr5:150945209..150945220,+#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr5:150945209..150945220, +
1.87e-86FFCP PHASE1:Mm9::chr6:113251570..113251578,+#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr6:113251570..113251578, +
1.87e-86FFCP PHASE2:Mm9::chr6:86746562..86746579,-#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr6:86746562..86746579, -
1.87e-86FFCP PHASE2:Mm9::chr15:58480061..58480066,+#_dce8c132c5fa3c8264cf9e4b787ecc16p5@Fer1l6
1.87e-86FFCP PHASE2:Mm9::chr9:42207777..42207789,-#_dce8c132c5fa3c8264cf9e4b787ecc16p7@Tecta
1.87e-86FFCP PHASE1:Mm9::chr10:107349392..107349413,-#_dce8c132c5fa3c8264cf9e4b787ecc16p2@Otogl
1.87e-86FFCP PHASE2:Mm9::chr4:63079735..63079745,-#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr4:63079735..63079745, -
1.87e-86FFCP PHASE2:Mm9::chr5:147854240..147854249,-#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr5:147854240..147854249, -
1.87e-86FFCP PHASE2:Mm9::chr10:107349430..107349440,-#_dce8c132c5fa3c8264cf9e4b787ecc16p3@Otogl
1.87e-86FFCP PHASE1:Mm9::chr7:139597684..139597691,+#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr7:139597684..139597691, +
1.87e-86FFCP PHASE1:Mm9::chr10:80806020..80806031,-#_dce8c132c5fa3c8264cf9e4b787ecc16p3@Gipc3
1.87e-86FFCP PHASE2:Mm9::chr10:80806047..80806059,-#_dce8c132c5fa3c8264cf9e4b787ecc16p4@Gipc3
1.87e-86FFCP PHASE2:Mm9::chr17:31335903..31335921,-#_dce8c132c5fa3c8264cf9e4b787ecc16p2@Tmprss3
1.87e-86FFCP PHASE1:Mm9::chr2:75320183..75320189,+#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr2:75320183..75320189, +
1.87e-86FFCP PHASE1:Mm9::chr17:13983179..13983190,+#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr17:13983179..13983190, +
1.87e-86FFCP PHASE1:Mm9::chr7:53496326..53496340,+#_dce8c132c5fa3c8264cf9e4b787ecc16p1@Otog
1.87e-86FFCP PHASE1:Mm9::chr6:30619443..30619450,-#_dce8c132c5fa3c8264cf9e4b787ecc16p13@Tsga14
1.87e-86FFCP PHASE1:Mm9::chr11:102123554..102123566,+#_dce8c132c5fa3c8264cf9e4b787ecc16p4@BC030867
1.87e-86FFCP PHASE2:Mm9::chr11:114603036..114603048,+#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr11:114603036..114603048, +
1.87e-86FFCP PHASE2:Mm9::chr16:93971325..93971337,-#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr16:93971325..93971337, -
1.87e-86FFCP PHASE1:Mm9::chr15:89215333..89215341,+#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr15:89215333..89215341, +
1.87e-86FFCP PHASE2:Mm9::chr1:154246932..154246939,+#_dce8c132c5fa3c8264cf9e4b787ecc16p7@Glt25d2
1.87e-86FFCP PHASE1:Mm9::chr1:172843813..172843834,-#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr1:172843813..172843834, -
1.87e-86FFCP PHASE2:Mm9::chr2:53464168..53464175,+#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr2:53464168..53464175, +
1.87e-86FFCP PHASE2:Mm9::chr5:72652660..72652667,+#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr5:72652660..72652667, +
1.87e-86FFCP PHASE2:Mm9::chr11:89702580..89702593,-#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr11:89702580..89702593, -
1.87e-86FFCP PHASE1:Mm9::chr16:93971367..93971379,-#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr16:93971367..93971379, -
1.87e-86FFCP PHASE2:Mm9::chr2:136942131..136942142,-#_dce8c132c5fa3c8264cf9e4b787ecc16p6@Jag1
1.87e-86FFCP PHASE2:Mm9::chr10:81091447..81091464,+#_dce8c132c5fa3c8264cf9e4b787ecc16p9@Ankrd24
1.87e-86FFCP PHASE1:Mm9::chr17:31335953..31335957,-#_dce8c132c5fa3c8264cf9e4b787ecc16p3@Tmprss3
1.87e-86FFCP PHASE1:Mm9::chr15:12848147..12848162,+#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr15:12848147..12848162, +
1.87e-86FFCP PHASE2:Mm9::chr1:78523144..78523177,+#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr1:78523144..78523177, +
1.87e-86FFCP PHASE2:Mm9::chr7:53496326..53496340,+#_dce8c132c5fa3c8264cf9e4b787ecc16p1@Otog
1.87e-86FFCP PHASE2:Mm9::chr5:3909310..3909321,+#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr5:3909310..3909321, +
1.87e-86FFCP PHASE2:Mm9::chr14:31283072..31283081,-#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr14:31283072..31283081, -
1.87e-86FFCP PHASE1:Mm9::chr3:154459231..154459240,+#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr3:154459231..154459240, +
1.87e-86FFCP PHASE2:Mm9::chr11:75421384..75421397,+#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr11:75421384..75421397, +
1.87e-86FFCP PHASE1:Mm9::chr1:154246932..154246939,+#_dce8c132c5fa3c8264cf9e4b787ecc16p7@Glt25d2
1.87e-86FFCP PHASE2:Mm9::chr8:13435173..13435186,+#_dce8c132c5fa3c8264cf9e4b787ecc16p6@Fam70b
1.87e-86FFCP PHASE2:Mm9::chr2:121206667..121206674,-#_dce8c132c5fa3c8264cf9e4b787ecc16p2@Strc
1.87e-86FFCP PHASE1:Mm9::chr9:42207998..42208009,-#_dce8c132c5fa3c8264cf9e4b787ecc16p6@Tecta
1.87e-86FFCP PHASE2:Mm9::chr2:67011921..67011934,+#_dce8c132c5fa3c8264cf9e4b787ecc16p2@Gm1322
1.87e-86FFCP PHASE2:Mm9::chr9:42207965..42207978,-#_dce8c132c5fa3c8264cf9e4b787ecc16p5@Tecta
1.87e-86FFCP PHASE1:Mm9::chr8:125802236..125802251,-#_dce8c132c5fa3c8264cf9e4b787ecc16p3@Fanca
1.87e-86FFCP PHASE1:Mm9::chr2:121206677..121206683,-#_dce8c132c5fa3c8264cf9e4b787ecc16p3@Strc
1.87e-86FFCP PHASE1:Mm9::chr10:108316802..108316807,-#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr10:108316802..108316807, -
1.87e-86FFCP PHASE2:Mm9::chr1:172843847..172843880,-#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr1:172843847..172843880, -
1.87e-86FFCP PHASE2:Mm9::chr19:4140290..4140321,+#_dce8c132c5fa3c8264cf9e4b787ecc16p2@Gpr152
1.87e-86FFCP PHASE1:Mm9::chr7:141605556..141605563,-#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr7:141605556..141605563, -
1.87e-86FFCP PHASE1:Mm9::chr1:194818647..194818660,-#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr1:194818647..194818660, -
1.87e-86FFCP PHASE2:Mm9::chr6:30619443..30619450,-#_dce8c132c5fa3c8264cf9e4b787ecc16p13@Tsga14
1.87e-86FFCP PHASE2:Mm9::chr9:42206784..42206793,-#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr9:42206784..42206793, -
1.87e-86FFCP PHASE2:Mm9::chr19:55255289..55255299,+#_dce8c132c5fa3c8264cf9e4b787ecc16p2@Tectb
1.87e-86FFCP PHASE2:Mm9::chr5:21371424..21371435,-#_dce8c132c5fa3c8264cf9e4b787ecc16p2@Slc26a5
1.87e-86FFCP PHASE1:Mm9::chr13:43699188..43699216,+#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr13:43699188..43699216, +
1.87e-86FFCP PHASE2:Mm9::chr11:120222470..120222516,+#_dce8c132c5fa3c8264cf9e4b787ecc16p2@Fscn2
1.87e-86FFCP PHASE1:Mm9::chr19:55255206..55255223,+#_dce8c132c5fa3c8264cf9e4b787ecc16p1@Tectb
1.87e-86FFCP PHASE2:Mm9::chr11:102123554..102123566,+#_dce8c132c5fa3c8264cf9e4b787ecc16p4@BC030867
1.87e-86FFCP PHASE2:Mm9::chr5:28035962..28035983,+#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr5:28035962..28035983, +
1.87e-86FFCP PHASE2:Mm9::chr3:81012915..81012923,+#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr3:81012915..81012923, +
1.87e-86FFCP PHASE2:Mm9::chr10:107349309..107349318,-#_dce8c132c5fa3c8264cf9e4b787ecc16p4@Otogl
1.87e-86FFCP PHASE2:Mm9::chr17:13983179..13983190,+#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr17:13983179..13983190, +
1.87e-86FFCP PHASE1:Mm9::chr9:42207397..42207408,-#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr9:42207397..42207408, -
1.87e-86FFCP PHASE1:Mm9::chr10:97109753..97109764,+#_dce8c132c5fa3c8264cf9e4b787ecc16p3@Epyc
1.87e-86FFCP PHASE1:Mm9::chr4:63079735..63079745,-#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr4:63079735..63079745, -
1.87e-86FFCP PHASE2:Mm9::chr13:78257518..78257522,+#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr13:78257518..78257522, +
1.87e-86FFCP PHASE2:Mm9::chr1:16651649..16651655,+#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr1:16651649..16651655, +
1.87e-86FFCP PHASE2:Mm9::chr2:29935952..29935993,+#_dce8c132c5fa3c8264cf9e4b787ecc16p7@Pkn3
1.87e-86FFCP PHASE1:Mm9::chr5:147854240..147854249,-#_dce8c132c5fa3c8264cf9e4b787ecc16p@chr5:147854240..147854249, -

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