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Revision as of 17:18, 15 June 2012

Name:mesenchyme
Definition:"Portion of tissue consisting of loosely organized undifferentiated mesodermal cells that give rise to such structures as connective tissues, blood, lymphatics, bone, and cartilage[XAO]. A mesh-like cell arrangement, less compact than an epithelium[ZFA]. The part of the embryonic mesoderm, consisting of loosely packed, unspecialized cells set in a gelatinous ground substance, from which connective tissue, bone, cartilage, and the circulatory and lymphatic systems develop[BTO]." [BTO:0001393, Wikipedia:Mesenchyme, ZFIN:curator]
Xrefs:
links:

AAO:0010427
AEO:0000145
BTO:0001393
EHDAA2:0003145
EV:0100007
[1]
ncithesaurus:Mesenchyme
TAO:0000393
VHOG:0000170
XAO:0003046

ZFA:0000393
Synonyms: "mesenchymal tissue" EXACT []
"mesenchyme tissue" EXACT []
"portion of mesenchymal tissue" EXACT []
"portion of mesenchyme tissue" EXACT []
Comments:This class was created automatically from a combination of ontologies
Alt_id: UBERON:XAO_0003046-ZFA_0000393
Subset: uberon_slim
vertebrate_core

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data


Parents

is_a:UBERON:0000479(tissue),UBERON:0004120(mesoderm-derived structure)
develops_from:UBERON:0000926(mesoderm)
part_of:UBERON:0009142(entire embryonic mesenchyme)



Children

is a:UBERON:0003422 (mesenchyme of umbilical cord),UBERON:0003918 (kidney mesenchyme),UBERON:0004161 (septum transversum),UBERON:0004208 (nephrogenic mesenchyme),UBERON:0005253 (head mesenchyme),UBERON:0005256 (trunk mesenchyme),UBERON:0006258 (lateral plate mesenchyme),UBERON:0006293 (spleen primordium),UBERON:0007524 (dense mesenchyme tissue),UBERON:0007530 (migrating mesenchyme population),UBERON:0009526 (maxillary process mesenchyme),UBERON:0009749 (limb mesenchyme),UBERON:0009751 (cardiac mesenchyme),UBERON:0009891 (facial mesenchyme),UBERON:0010083 (future dermis),UBERON:0014387 (mesenchyme derived from neural crest)
develops from:UBERON:0001046 (hindgut),UBERON:0002514 (intramembranous bone)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology


Human (Homo sapiens)

  • 10813-111B3 (normal embryonic palatal mesenchymal cell line:HEPM)
  • 11214-116A8 (Mesenchymal stem cells - umbilical, donor0)
  • 11539-120A9 (Mesenchymal Stem Cells - umbilical, donor1)
  • 11548-120B9 (Mesenchymal Stem Cells - Wharton's Jelly, donor1)
  • 11549-120C1 (Multipotent Cord Blood Unrestricted Somatic Stem Cells, donor1)
  • 11619-122A8 (Mesenchymal Stem Cells - umbilical, donor2)
  • 11628-122B8
  • 11629-122B9 (Multipotent Cord Blood Unrestricted Somatic Stem Cells, donor2)
  • 11700-123A8 (Mesenchymal Stem Cells - umbilical, donor3)


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0003104 (mesenchyme), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data