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|ontology_enrichment_disease=DOID:2394!3.84e-08!14
|ontology_enrichment_disease=DOID:2394!3.84e-08!14
|ontology_enrichment_uberon=UBERON:0000486!6.24e-13!82;UBERON:0000914!3.62e-11!83;UBERON:0002329!3.62e-11!83;UBERON:0003077!3.62e-11!83;UBERON:0003059!3.62e-11!83;UBERON:0007282!3.62e-11!83;UBERON:0009618!3.62e-11!83;UBERON:0007285!3.62e-11!83;UBERON:0003102!2.61e-10!95;UBERON:0004290!1.80e-09!70;UBERON:0001134!3.86e-08!61;UBERON:0002036!3.86e-08!61;UBERON:0003082!3.86e-08!61;UBERON:0002199!1.04e-07!45;UBERON:0002416!1.04e-07!45;UBERON:0002385!1.10e-07!63;UBERON:0001015!1.10e-07!63;UBERON:0000383!1.10e-07!63;UBERON:0005256!2.44e-07!143;UBERON:0002097!5.53e-07!40;UBERON:0000475!7.52e-07!365
|ontology_enrichment_uberon=UBERON:0000486!6.24e-13!82;UBERON:0000914!3.62e-11!83;UBERON:0002329!3.62e-11!83;UBERON:0003077!3.62e-11!83;UBERON:0003059!3.62e-11!83;UBERON:0007282!3.62e-11!83;UBERON:0009618!3.62e-11!83;UBERON:0007285!3.62e-11!83;UBERON:0003102!2.61e-10!95;UBERON:0004290!1.80e-09!70;UBERON:0001134!3.86e-08!61;UBERON:0002036!3.86e-08!61;UBERON:0003082!3.86e-08!61;UBERON:0002199!1.04e-07!45;UBERON:0002416!1.04e-07!45;UBERON:0002385!1.10e-07!63;UBERON:0001015!1.10e-07!63;UBERON:0000383!1.10e-07!63;UBERON:0005256!2.44e-07!143;UBERON:0002097!5.53e-07!40;UBERON:0000475!7.52e-07!365
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}}
}}

Revision as of 17:45, 8 August 2012


Full id: C1890_Small_nasal_Mammary_Urothelial_Keratinocyte_squamous_oral



Phase1 CAGE Peaks

Hg19::chr2:208104240..208104269,+p2@ENST00000440326
Hg19::chr2:208104288..208104304,+p4@ENST00000440326
Hg19::chr2:208104351..208104375,+p1@ENST00000440326
Hg19::chr2:208104377..208104397,+p3@ENST00000440326
Hg19::chr2:208104402..208104413,+p5@ENST00000440326


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

Cell Type
Ontology termp-valuen
animal cell1.32e-22679
eukaryotic cell1.32e-22679
non-terminally differentiated cell1.62e-19180
somatic cell6.85e-19591
native cell2.07e-15722
fibroblast1.78e-1275
embryonic cell1.96e-12248
muscle precursor cell7.41e-1057
myoblast7.41e-1057
multi-potent skeletal muscle stem cell7.41e-1057
muscle cell1.10e-0854
endo-epithelial cell5.45e-0843
respiratory epithelial cell1.08e-0713
contractile cell1.53e-0759
electrically responsive cell9.53e-0760
electrically active cell9.53e-0760
Uber Anatomy
Ontology termp-valuen
multilaminar epithelium6.24e-1382
somite3.62e-1183
paraxial mesoderm3.62e-1183
presomitic mesoderm3.62e-1183
presumptive segmental plate3.62e-1183
trunk paraxial mesoderm3.62e-1183
presumptive paraxial mesoderm3.62e-1183
surface structure2.61e-1095
dermomyotome1.80e-0970
skeletal muscle tissue3.86e-0861
striated muscle tissue3.86e-0861
myotome3.86e-0861
integument1.04e-0745
integumental system1.04e-0745
muscle tissue1.10e-0763
musculature1.10e-0763
musculature of body1.10e-0763
trunk mesenchyme2.44e-07143
skin of body5.53e-0740
organism subdivision7.52e-07365
Disease
Ontology termp-valuen
ovarian cancer3.84e-0814


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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