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{{CL
{{CL
|id=CL:0000860
|alt_id=
|name=classical monocyte
|namespace=cell
|def="A type of monocyte that responds rapidly to microbial stimuli by secreting cytokines and antimicrobial factors. This cell type is characterized by high expression of CCR2 in both rodents and humans, and of being larger size than non-classical monocytes." [GO_REF:0000031, PMID:16322748, PMID:18303997, PMID:20628149, PMID:20870168]
|xref=
|is_a=CL:0000576
|synonym="inflammatory monocyte" EXACT []
|comment=Markers: CCR2+CXCCR1<low> (human, mouse, rat).
|comment=Markers: CCR2+CXCCR1<low> (human, mouse, rat).
|alt_id=
|disjoint_from=
|union_of=
|created_by=
|created_by=
|obo_creation_date=
|def="A type of monocyte that responds rapidly to microbial stimuli by secreting cytokines and antimicrobial factors. This cell type is characterized by high expression of CCR2 in both rodents and humans, and of being larger size than non-classical monocytes." [GO_REF:0000031, PMID:16322748, PMID:18303997, PMID:20628149, PMID:20870168]
|subset=
|adjacent_to=
|derives_from=
|derives_from=
|develops_from=
|develops_from=
|disjoint_from=
|has_quality=
|has_quality=
|id=CL:0000860
|is_a=CL:0000234 ;;CL:0000576
|is_obsolete=
|located_in=
|located_in=
|name=classical monocyte
|namespace=FANTOM
|obo_creation_date=
|part_of=
|part_of=
|preceded_by=
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl.owl;;IAO:0000412 http://purl.obolibrary.org/obo/efo.owl
|subset=
|synonym="inflammatory monocyte" EXACT []
|union_of=
|xref=
}}
}}

Latest revision as of 16:38, 12 September 2014

Name:classical monocyte
Namespace:FANTOM
Definition:"A type of monocyte that responds rapidly to microbial stimuli by secreting cytokines and antimicrobial factors. This cell type is characterized by high expression of CCR2 in both rodents and humans, and of being larger size than non-classical monocytes." [GO_REF:0000031, PMID:16322748, PMID:18303997, PMID:20628149, PMID:20870168]
Synonyms: "inflammatory monocyte" EXACT []
Comments:Markers: CCR2+CXCCR1<low> (human, mouse, rat).


Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:CL:0000234(phagocyte),CL:0000576(monocyte)



Children


is a:CL:0002057 (CD14-positive, CD16-negative classical monocyte)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)


FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.

Human (Homo sapiens)

... further results Mouse (Mus musculus)

... further results


Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000860 (classical monocyte), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
2.95e-173FFCP PHASE1:Hg19::chr7:44661060..44661101,-#_ffbc737bdb0d846e2b2d96cdac5cadd2p@chr7:44661060..44661101, -
2.95e-173FFCP PHASE2:Hg19::chr7:44661060..44661101,-#_ffbc737bdb0d846e2b2d96cdac5cadd2p@chr7:44661060..44661101, -
5.66e-173FFCP PHASE2:Hg19::chr17:72628050..72628077,-#_d6c779249e86f4b4bb7374339c1734c2p@chr17:72628050..72628077, -
5.66e-173FFCP PHASE1:Hg19::chr17:72628050..72628077,-#_d6c779249e86f4b4bb7374339c1734c2p@chr17:72628050..72628077, -
3.48e-171FFCP PHASE1:Hg19::chr17:72607002..72607029,+#_ae67142d915a0edc97e83f4a20361e33p@chr17:72607002..72607029, +
3.48e-171FFCP PHASE2:Hg19::chr17:72607002..72607029,+#_ae67142d915a0edc97e83f4a20361e33p@chr17:72607002..72607029, +
2.61e-167FFCP PHASE2:Hg19::chr17:72606825..72606838,-#_96d6e8e066691da134ad971237814f0dp@chr17:72606825..72606838, -
2.61e-167FFCP PHASE1:Hg19::chr17:72606825..72606838,-#_96d6e8e066691da134ad971237814f0dp@chr17:72606825..72606838, -
1.41e-166FFCP PHASE2:Hg19::chr17:72607152..72607174,-#_29cff9f06f98ec8f6612669a9c8ad35ep@chr17:72607152..72607174, -
1.41e-166FFCP PHASE1:Hg19::chr17:72607152..72607174,-#_29cff9f06f98ec8f6612669a9c8ad35ep@chr17:72607152..72607174, -
1.31e-165FFCP PHASE2:Hg19::chr17:72607351..72607373,-#_5213725da8543b8dee4af44602cbfff9p@chr17:72607351..72607373, -
1.31e-165FFCP PHASE1:Hg19::chr17:72607351..72607373,-#_5213725da8543b8dee4af44602cbfff9p@chr17:72607351..72607373, -
8.2e-165FFCP PHASE1:Hg19::chr1:120593738..120593745,+#_86600724e49c9d36db217b867d3cc53ap@chr1:120593738..120593745, +
8.2e-165FFCP PHASE2:Hg19::chr1:120593738..120593745,+#_86600724e49c9d36db217b867d3cc53ap@chr1:120593738..120593745, +
1.7e-164FFCP PHASE1:Hg19::chr14:55249943..55249971,+#_d74dca48b1bd4ae3156cfb4d0dbecd7dp@chr14:55249943..55249971, +
1.7e-164FFCP PHASE2:Hg19::chr14:55249943..55249971,+#_d74dca48b1bd4ae3156cfb4d0dbecd7dp@chr14:55249943..55249971, +
6.24e-163FFCP PHASE2:Hg19::chr8:11754835..11754867,-#_a4a7cbc2f8c28833875fcee564473e8cp1@ENST00000525252
6.24e-163FFCP PHASE1:Hg19::chr8:11754835..11754867,-#_a4a7cbc2f8c28833875fcee564473e8cp1@ENST00000525252
2.9e-162FFCP PHASE1:Hg19::chr12:125197870..125197907,+#_f6a32b395ee9429ce85960dd439c6806p@chr12:125197870..125197907, +
2.9e-162FFCP PHASE2:Hg19::chr12:125197870..125197907,+#_f6a32b395ee9429ce85960dd439c6806p@chr12:125197870..125197907, +
2.93e-162FFCP PHASE1:Hg19::chr17:72606678..72606702,-#_394e23847828a95efd4fc989d640ddbfp@chr17:72606678..72606702, -
2.93e-162FFCP PHASE2:Hg19::chr17:72606678..72606702,-#_394e23847828a95efd4fc989d640ddbfp@chr17:72606678..72606702, -
3.23e-162FFCP PHASE2:Hg19::chr22:17717917..17717939,-#_f21b07a2c036c835d3561176aee82451p@chr22:17717917..17717939, -
3.23e-162FFCP PHASE1:Hg19::chr22:17717917..17717939,-#_f21b07a2c036c835d3561176aee82451p@chr22:17717917..17717939, -
4.13e-162FFCP PHASE2:Hg19::chr5:156534439..156534470,+#_53777fbc6887569dfb38a1a437f5090ep@chr5:156534439..156534470, +
4.13e-162FFCP PHASE1:Hg19::chr5:156534439..156534470,+#_53777fbc6887569dfb38a1a437f5090ep@chr5:156534439..156534470, +
1.23e-161FFCP PHASE1:Hg19::chr9:137300477..137300490,+#_284eb9189d2ae304f76303b2a379566fp@chr9:137300477..137300490, +
1.23e-161FFCP PHASE2:Hg19::chr9:137300477..137300490,+#_284eb9189d2ae304f76303b2a379566fp@chr9:137300477..137300490, +
6.16e-160FFCP PHASE2:Hg19::chr1:149901972..149901989,-#_e32e3fb4cc49a5d7342f2f458930f90fp@chr1:149901972..149901989, -
6.16e-160FFCP PHASE1:Hg19::chr1:149901972..149901989,-#_e32e3fb4cc49a5d7342f2f458930f90fp@chr1:149901972..149901989, -
3.22e-159FFCP PHASE2:Hg19::chr2:145276939..145276960,+#_d18873c889e7628e74a9694666eba060p2@ZEB2-AS1
3.22e-159FFCP PHASE1:Hg19::chr2:145276939..145276960,+#_d18873c889e7628e74a9694666eba060p2@ZEB2-AS1
4.01e-159FFCP PHASE1:Hg19::chr11:68847955..68847972,-#_b688994235a5e3395b51aea5c028e85ep@chr11:68847955..68847972, -
4.01e-159FFCP PHASE2:Hg19::chr11:68847955..68847972,-#_b688994235a5e3395b51aea5c028e85ep@chr11:68847955..68847972, -
1.14e-158FFCP PHASE2:Hg19::chr11:68847043..68847057,+#_565e9c6849022f194d9ee15a3e06a75ep@chr11:68847043..68847057, +
1.14e-158FFCP PHASE1:Hg19::chr11:68847043..68847057,+#_565e9c6849022f194d9ee15a3e06a75ep@chr11:68847043..68847057, +
5.8e-158FFCP PHASE2:Hg19::chr1:108592890..108592921,-#_07a9d05e8316865ff88ec0a8f0ef7cdbp@chr1:108592890..108592921, -
5.8e-158FFCP PHASE1:Hg19::chr1:108592890..108592921,-#_07a9d05e8316865ff88ec0a8f0ef7cdbp@chr1:108592890..108592921, -
2.44e-157FFCP PHASE1:Hg19::chr7:949680..949694,-#_a574669749cf64fdb44c1a71c14a1f37p@chr7:949680..949694, -
2.44e-157FFCP PHASE2:Hg19::chr7:949680..949694,-#_a574669749cf64fdb44c1a71c14a1f37p@chr7:949680..949694, -
4.86e-157FFCP PHASE2:Hg19::chr7:48009999..48010016,+#_90e77a1129ad14b389ef32958f956e55p@chr7:48009999..48010016, +
4.86e-157FFCP PHASE1:Hg19::chr7:48009999..48010016,+#_90e77a1129ad14b389ef32958f956e55p@chr7:48009999..48010016, +
5.49e-157FFCP PHASE2:Hg19::chr4:185314351..185314392,+#_6ea6b970863c9664450ca82ad42dc3aap@chr4:185314351..185314392, +
5.49e-157FFCP PHASE1:Hg19::chr4:185314351..185314392,+#_6ea6b970863c9664450ca82ad42dc3aap@chr4:185314351..185314392, +
8.29e-157FFCP PHASE2:Hg19::chr16:82229835..82229848,+#_86369d6017555b78569029bae13ab551p@chr16:82229835..82229848, +
8.29e-157FFCP PHASE1:Hg19::chr16:82229835..82229848,+#_86369d6017555b78569029bae13ab551p@chr16:82229835..82229848, +
2.1e-156FFCP PHASE2:Hg19::chr20:5634031..5634046,+#_c7f419cf50c9661dd717328183ea10dfp@chr20:5634031..5634046, +
2.1e-156FFCP PHASE1:Hg19::chr20:5634031..5634046,+#_c7f419cf50c9661dd717328183ea10dfp@chr20:5634031..5634046, +
4.29e-156FFCP PHASE2:Hg19::chr4:159731607..159731627,+#_b55323b0f8cf3c1374749e44da1ed96cp@chr4:159731607..159731627, +
4.29e-156FFCP PHASE1:Hg19::chr4:159731607..159731627,+#_b55323b0f8cf3c1374749e44da1ed96cp@chr4:159731607..159731627, +
1.66e-155FFCP PHASE1:Hg19::chr9:102353301..102353315,-#_c0129b1405e22923d148a7909705668bp@chr9:102353301..102353315, -
1.66e-155FFCP PHASE2:Hg19::chr9:102353301..102353315,-#_c0129b1405e22923d148a7909705668bp@chr9:102353301..102353315, -
3.6e-155FFCP PHASE1:Hg19::chr2:145450907..145450928,-#_d171907a6acc31860bfc2019088c9715p@chr2:145450907..145450928, -
3.6e-155FFCP PHASE2:Hg19::chr2:145450907..145450928,-#_d171907a6acc31860bfc2019088c9715p@chr2:145450907..145450928, -
3.76e-155FFCP PHASE2:Hg19::chr17:72628206..72628246,+#_83af5762cbb69d6efd42b5a8d0faf227p@chr17:72628206..72628246, +
3.76e-155FFCP PHASE1:Hg19::chr17:72628206..72628246,+#_83af5762cbb69d6efd42b5a8d0faf227p@chr17:72628206..72628246, +
1.6e-154FFCP PHASE2:Hg19::chr8:11755021..11755054,+#_2a5a54194ff3cb1b167614a8f69424aep@chr8:11755021..11755054, +
1.6e-154FFCP PHASE1:Hg19::chr8:11755021..11755054,+#_2a5a54194ff3cb1b167614a8f69424aep@chr8:11755021..11755054, +
1.99e-154FFCP PHASE2:Hg19::chr2:145421047..145421067,+#_39de19238b735e4b51618daea6ba14f5p@chr2:145421047..145421067, +
1.99e-154FFCP PHASE1:Hg19::chr2:145421047..145421067,+#_39de19238b735e4b51618daea6ba14f5p@chr2:145421047..145421067, +
4.18e-154FFCP PHASE2:Hg19::chr6:106348152..106348164,+#_622c4a545db6296b7a5bbd83d5a4fa37p@chr6:106348152..106348164, +
4.18e-154FFCP PHASE1:Hg19::chr6:106348152..106348164,+#_622c4a545db6296b7a5bbd83d5a4fa37p@chr6:106348152..106348164, +
9.99e-154FFCP PHASE1:Hg19::chr16:17469894..17469904,+#_1379c863a30ab032d329444812720b69p@chr16:17469894..17469904, +
9.99e-154FFCP PHASE2:Hg19::chr16:17469894..17469904,+#_1379c863a30ab032d329444812720b69p@chr16:17469894..17469904, +
1.29e-153FFCP PHASE1:Hg19::chr1:40006573..40006589,-#_5a89ade2a05dc44ae71e363eccba02b5p@chr1:40006573..40006589, -
1.29e-153FFCP PHASE2:Hg19::chr1:40006573..40006589,-#_5a89ade2a05dc44ae71e363eccba02b5p@chr1:40006573..40006589, -
1.38e-153FFCP PHASE1:Hg19::chr7:111720716..111720750,+#_034dd644ab936e3c74792e56f17b058ap@chr7:111720716..111720750, +
1.38e-153FFCP PHASE2:Hg19::chr7:111720716..111720750,+#_034dd644ab936e3c74792e56f17b058ap@chr7:111720716..111720750, +
1.95e-153FFCP PHASE2:Hg19::chr3:128943968..128943986,+#_b0eb7c500cd59d530d87db6e56e32b41p@chr3:128943968..128943986, +
1.95e-153FFCP PHASE1:Hg19::chr3:128943968..128943986,+#_b0eb7c500cd59d530d87db6e56e32b41p@chr3:128943968..128943986, +
3.44e-153FFCP PHASE2:Hg19::chr2:58339774..58339779,-#_4f226446a9a3e411ae7e707eed00955bp@chr2:58339774..58339779, -
3.44e-153FFCP PHASE1:Hg19::chr2:58339774..58339779,-#_4f226446a9a3e411ae7e707eed00955bp@chr2:58339774..58339779, -
4.04e-153FFCP PHASE1:Hg19::chr11:61737685..61737701,-#_b1f8761655ee19b09e94279d0ad5e65cp@chr11:61737685..61737701, -
4.04e-153FFCP PHASE2:Hg19::chr11:61737685..61737701,-#_b1f8761655ee19b09e94279d0ad5e65cp@chr11:61737685..61737701, -
5.57e-153FFCP PHASE1:Hg19::chr11:10921401..10921434,-#_efc3a5a4569338e4a29805c512b50b93p@chr11:10921401..10921434, -
5.57e-153FFCP PHASE2:Hg19::chr11:10921401..10921434,-#_efc3a5a4569338e4a29805c512b50b93p@chr11:10921401..10921434, -
2.07e-152FFCP PHASE1:Hg19::chr1:212659324..212659370,-#_716dd5d1ffd85c0afd08143c392c81aep@chr1:212659324..212659370, -
2.07e-152FFCP PHASE2:Hg19::chr1:212659324..212659370,-#_716dd5d1ffd85c0afd08143c392c81aep@chr1:212659324..212659370, -
2.23e-152FFCP PHASE1:Hg19::chr19:4812881..4812891,-#_25387d2560781c0f7ec8a53875fcbae9p@chr19:4812881..4812891, -
2.23e-152FFCP PHASE2:Hg19::chr19:4812881..4812891,-#_25387d2560781c0f7ec8a53875fcbae9p@chr19:4812881..4812891, -
3.99e-152FFCP PHASE1:Hg19::chr18:13577406..13577430,-#_f86776b6e957f963101fae92d1cf8fe8p@chr18:13577406..13577430, -
3.99e-152FFCP PHASE2:Hg19::chr18:13577406..13577430,-#_f86776b6e957f963101fae92d1cf8fe8p@chr18:13577406..13577430, -
4.17e-152FFCP PHASE1:Hg19::chr9:137264021..137264038,+#_87f8e7f1130d48278c575bcc7e166210p@chr9:137264021..137264038, +
4.17e-152FFCP PHASE2:Hg19::chr9:137264021..137264038,+#_87f8e7f1130d48278c575bcc7e166210p@chr9:137264021..137264038, +
4.44e-152FFCP PHASE2:Hg19::chr8:48173159..48173173,+#_ddbdd255689cdf0e898fc03a8a6a0089p6@KIAA0146
4.44e-152FFCP PHASE1:Hg19::chr8:48173159..48173173,+#_ddbdd255689cdf0e898fc03a8a6a0089p6@KIAA0146
6.49e-152FFCP PHASE2:Hg19::chr8:71452856..71452863,+#_288968d36f395b462700da1c9ae347dcp@chr8:71452856..71452863, +
6.49e-152FFCP PHASE1:Hg19::chr8:71452856..71452863,+#_288968d36f395b462700da1c9ae347dcp@chr8:71452856..71452863, +
6.68e-152FFCP PHASE1:Hg19::chr22:28065655..28065677,+#_2db14910e199067f5af9b2fc0e57c474p@chr22:28065655..28065677, +
6.68e-152FFCP PHASE2:Hg19::chr22:28065655..28065677,+#_2db14910e199067f5af9b2fc0e57c474p@chr22:28065655..28065677, +
1.17e-151FFCP PHASE1:Hg19::chr20:5626328..5626343,+#_e51bdb3afd32a2ef089dd63186d0ee74p@chr20:5626328..5626343, +
1.17e-151FFCP PHASE2:Hg19::chr20:5626328..5626343,+#_e51bdb3afd32a2ef089dd63186d0ee74p@chr20:5626328..5626343, +
2.27e-151FFCP PHASE1:Hg19::chr7:151622937..151622965,-#_15f5ef29bac75798df76390c073f1326p@chr7:151622937..151622965, -
2.27e-151FFCP PHASE2:Hg19::chr7:151622937..151622965,-#_15f5ef29bac75798df76390c073f1326p@chr7:151622937..151622965, -
6.5e-151FFCP PHASE1:Hg19::chr17:72635873..72635891,-#_ba9e6bb0a14b4b25c4ba2625c93890e9p@chr17:72635873..72635891, -
6.5e-151FFCP PHASE2:Hg19::chr17:72635873..72635891,-#_ba9e6bb0a14b4b25c4ba2625c93890e9p@chr17:72635873..72635891, -
1.04e-150FFCP PHASE1:Hg19::chr17:72636264..72636304,+#_144f9ad38ef997e36d4d95e377c86348p@chr17:72636264..72636304, +
1.04e-150FFCP PHASE2:Hg19::chr17:72636264..72636304,+#_144f9ad38ef997e36d4d95e377c86348p@chr17:72636264..72636304, +
1.28e-150FFCP PHASE1:Hg19::chr7:2814742..2814772,+#_74663df81577f470ddf962a89659072bp@chr7:2814742..2814772, +
1.28e-150FFCP PHASE2:Hg19::chr7:2814742..2814772,+#_74663df81577f470ddf962a89659072bp@chr7:2814742..2814772, +

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