UBERON:0000485: Difference between revisions
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{{UBERON | {{UBERON | ||
| | |alt_id=UBERON:CARO_0000068-FMA_45567-ZFA_0001496 | ||
|comment= | |comment= | ||
|created_by= | |created_by= | ||
| | |def="Unilaminar epithelium, which consists of a single layer of columnar cells. Examples: ciliated columnar epithelium, gastric epithelium, microvillus columnar epithelium.[FMA]" [CARO:MAH, FMA:FMA, Wikipedia:Simple_columnar_epithelium] | ||
|derives_from= | |derives_from= | ||
|develops_from= | |develops_from= | ||
|disjoint_from= | |||
|has_quality= | |has_quality= | ||
|id=UBERON:0000485 | |||
|is_a=UBERON:0000490 ;;UBERON:0012274 | |||
|is_obsolete= | |||
|located_in= | |located_in= | ||
|name=simple columnar epithelium | |||
|namespace=FANTOM | |||
|obo_creation_date= | |||
|part_of= | |part_of= | ||
|preceded_by= | |||
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl;;UBPROP:0000001 "Unilaminar epithelium that consists of a single layer of columnar cells.[AAO]" xsd:string;;UBPROP:0000001 "Unilaminar epithelium that consists of a single layer of columnar cells.[CARO]" xsd:string;;UBPROP:0000001 "Unilaminar epithelium that consists of a single layer of columnar cells.[TAO]" xsd:string | |property_value=IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl;;UBPROP:0000001 "Unilaminar epithelium that consists of a single layer of columnar cells.[AAO]" xsd:string;;UBPROP:0000001 "Unilaminar epithelium that consists of a single layer of columnar cells.[CARO]" xsd:string;;UBPROP:0000001 "Unilaminar epithelium that consists of a single layer of columnar cells.[TAO]" xsd:string | ||
| | |subset=uberon_slim;;vertebrate_core | ||
| | |synonym="columnar epithelium" EXACT [EHDAA2:0003068];;"columnar epithlium" EXACT [AEO:0000068];;"epithelium simplex columnare" EXACT [];;"simple columnar epithelium" EXACT [] | ||
|union_of= | |||
|xref=AAO:0010063;;AEO:0000068;;BILA:0000068;;CARO:0000068;;EHDAA2:0003068;;FBbt:00007027;;FMA:45567;;HAO:0000068;;http://upload.wikimedia.org/wikipedia/commons/8/8b/Gray1059.png;;http://upload.wikimedia.org/wikipedia/commons/thumb/8/8b/Gray1059.png/200px-Gray1059.png;;ncithesaurus:Simple_Columnar_Epithelium;;TAO:0001496;;XAO:0004008;;ZFA:0001496 | |||
}} | }} |
Latest revision as of 17:10, 12 September 2014
Name: | simple columnar epithelium | ||
---|---|---|---|
Namespace: | FANTOM | ||
Definition: | "Unilaminar epithelium, which consists of a single layer of columnar cells. Examples: ciliated columnar epithelium, gastric epithelium, microvillus columnar epithelium.[FMA]" [CARO:MAH, FMA:FMA, Wikipedia:Simple_columnar_epithelium] | ||
Xrefs: |
| ||
Synonyms: |
"columnar epithelium" EXACT [EHDAA2:0003068] "columnar epithlium" EXACT [AEO:0000068] "epithelium simplex columnare" EXACT [] "simple columnar epithelium" EXACT [] | ||
Alt_id: | UBERON:CARO_0000068-FMA_45567-ZFA_0001496 | ||
Subset: |
uberon_slim vertebrate_core |
Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data
Parents
is_a: | UBERON:0000490(unilaminar epithelium),UBERON:0012274(columnar epithelium) |
---|
Children
is a: | UBERON:0001277 (intestinal epithelium),UBERON:0001997 (olfactory epithelium),UBERON:0002031 (epithelium of bronchus),UBERON:0007497 (developing epithelial placode) |
---|
Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology
Human (Homo sapiens)
- 10275-104E5
- 10303-104H6
- 10331-105B7
- 10420-106C6 (colon carcinoma cell line:COLO-320)
- 10511-107D7
- 10513-107D9 (colon carcinoma cell line:CACO-2)
- 10523-107F1
- 10557-107I8
- 10635-108I5
- 10653-109B5
... further results Mouse (Mus musculus)
- 10275-104E5
- 10303-104H6
- 10331-105B7
- 10420-106C6 (colon carcinoma cell line:COLO-320)
- 10511-107D7
- 10513-107D9 (colon carcinoma cell line:CACO-2)
- 10523-107F1
- 10557-107I8
- 10635-108I5
- 10653-109B5
Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0000485 (simple columnar epithelium), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data
P-value | FFCP | Short description |
---|---|---|
7.63e-72 | FFCP PHASE2:Mm9::chr17:46693370..46693378,+#_20d3e24d138e2f97617e8acc53747bb6 | p@chr17:46693370..46693378, + |
7.63e-72 | FFCP PHASE1:Mm9::chr17:46693370..46693378,+#_20d3e24d138e2f97617e8acc53747bb6 | p@chr17:46693370..46693378, + |
4.29e-63 | FFCP PHASE2:Mm9::chr8:122335239..122335244,+#_f47b805e032d159f11449d994684bc82 | p@chr8:122335239..122335244, + |
4.29e-63 | FFCP PHASE1:Mm9::chr8:122335239..122335244,+#_f47b805e032d159f11449d994684bc82 | p@chr8:122335239..122335244, + |
2.02e-58 | FFCP PHASE2:Mm9::chr17:57201412..57201418,-#_c3f59912537da0ca29411e99a7250f6c | p@chr17:57201412..57201418, - |
2.02e-58 | FFCP PHASE1:Mm9::chr17:57201412..57201418,-#_c3f59912537da0ca29411e99a7250f6c | p@chr17:57201412..57201418, - |
3.89e-56 | FFCP PHASE1:Mm9::chr4:155434167..155434177,+#_51abe6f490857572a7597040de1823c8 | p@chr4:155434167..155434177, + |
3.89e-56 | FFCP PHASE2:Mm9::chr4:155434167..155434177,+#_51abe6f490857572a7597040de1823c8 | p@chr4:155434167..155434177, + |
2.49e-55 | FFCP PHASE2:Mm9::chr8:64192378..64192389,+#_0a5e502836dd297ae8e3f866d7947de6 | p@chr8:64192378..64192389, + |
2.49e-55 | FFCP PHASE1:Mm9::chr8:64192378..64192389,+#_0a5e502836dd297ae8e3f866d7947de6 | p@chr8:64192378..64192389, + |
2.97e-53 | FFCP PHASE2:Mm9::chr3:122215917..122215967,-#_7652b27b09928ad062dcce167d452da3 | p@chr3:122215917..122215967, - |
2.97e-53 | FFCP PHASE1:Mm9::chr3:122215917..122215967,-#_7652b27b09928ad062dcce167d452da3 | p@chr3:122215917..122215967, - |
5.19e-53 | FFCP PHASE1:Mm9::chr2:143738263..143738267,+#_bb5f3459be531b367c14d2b4608650d3 | p@chr2:143738263..143738267, + |
5.19e-53 | FFCP PHASE2:Mm9::chr2:143738263..143738267,+#_bb5f3459be531b367c14d2b4608650d3 | p@chr2:143738263..143738267, + |
3.5e-50 | FFCP PHASE1:Mm9::chr5:135465906..135465912,+#_fb79677e5065acd44f879c6db322acc5 | p@chr5:135465906..135465912, + |
3.5e-50 | FFCP PHASE2:Mm9::chr5:135465906..135465912,+#_fb79677e5065acd44f879c6db322acc5 | p@chr5:135465906..135465912, + |
8.87e-50 | FFCP PHASE2:Mm9::chr7:4101973..4101978,-#_d85ad09178263a6e502c18888cf7a278 | p4@Leng9 |
8.87e-50 | FFCP PHASE1:Mm9::chr7:4101973..4101978,-#_d85ad09178263a6e502c18888cf7a278 | p4@Leng9 |
1.7e-49 | FFCP PHASE1:Mm9::chr7:4101821..4101832,-#_c0cbb2cf283e8cfa42581a9d51a35253 | p5@Leng9 |
1.7e-49 | FFCP PHASE2:Mm9::chr7:4101821..4101832,-#_c0cbb2cf283e8cfa42581a9d51a35253 | p5@Leng9 |
2.26e-48 | FFCP PHASE1:Mm9::chr9:69315761..69315767,+#_8917e4f3bd83317878bd024c53ee29c5 | p@chr9:69315761..69315767, + |
2.26e-48 | FFCP PHASE2:Mm9::chr9:69315761..69315767,+#_8917e4f3bd83317878bd024c53ee29c5 | p@chr9:69315761..69315767, + |
1.34e-47 | FFCP PHASE2:Mm9::chr12:86771033..86771037,-#_bba97d02752fdda6d70c501c6e0c4652 | p@chr12:86771033..86771037, - |
1.34e-47 | FFCP PHASE1:Mm9::chr12:86771033..86771037,-#_bba97d02752fdda6d70c501c6e0c4652 | p@chr12:86771033..86771037, - |
1.54e-46 | FFCP PHASE1:Mm9::chr5:145119593..145119596,+#_197ee53a2f4e7946f4eed2b83a6900d1 | p@chr5:145119593..145119596, + |
1.54e-46 | FFCP PHASE2:Mm9::chr5:145119593..145119596,+#_197ee53a2f4e7946f4eed2b83a6900d1 | p@chr5:145119593..145119596, + |
2.02e-46 | FFCP PHASE1:Mm9::chr13:49066571..49066574,-#_126ef5a0d8df98975063f6f7e19f8443 | p@chr13:49066571..49066574, - |
2.02e-46 | FFCP PHASE2:Mm9::chr13:49066571..49066574,-#_126ef5a0d8df98975063f6f7e19f8443 | p@chr13:49066571..49066574, - |
3.03e-46 | FFCP PHASE2:Mm9::chr11:96797681..96797709,-#_fdf1dbaf1fe4e1445c667e18615c9668 | p@chr11:96797681..96797709, - |
3.03e-46 | FFCP PHASE1:Mm9::chr11:96797681..96797709,-#_fdf1dbaf1fe4e1445c667e18615c9668 | p@chr11:96797681..96797709, - |
5.14e-46 | FFCP PHASE1:Mm9::chr18:36576247..36576252,-#_d221d279c81d41e36dd563b08c1dad23 | p@chr18:36576247..36576252, - |
5.14e-46 | FFCP PHASE2:Mm9::chr18:36576247..36576252,-#_d221d279c81d41e36dd563b08c1dad23 | p@chr18:36576247..36576252, - |
8.93e-46 | FFCP PHASE1:Mm9::chr9:66888939..66888949,+#_32d03b7d06767ae23684c5f8fd5d8bce | p@chr9:66888939..66888949, + |
8.93e-46 | FFCP PHASE2:Mm9::chr9:66888939..66888949,+#_32d03b7d06767ae23684c5f8fd5d8bce | p@chr9:66888939..66888949, + |
9.75e-45 | FFCP PHASE1:Hg19::chr9:35801527..35801540,+#_797e59de150583da8fa3a889d86af3ab | p@chr9:35801527..35801540, + |
9.75e-45 | FFCP PHASE2:Hg19::chr9:35801527..35801540,+#_797e59de150583da8fa3a889d86af3ab | p@chr9:35801527..35801540, + |
1.39e-43 | FFCP PHASE1:Mm9::chr7:52317191..52317193,+#_742fd2a5303950f9610ed6e844ebdafb | p@chr7:52317191..52317193, + |
1.39e-43 | FFCP PHASE2:Mm9::chr7:52317191..52317193,+#_742fd2a5303950f9610ed6e844ebdafb | p@chr7:52317191..52317193, + |
1.74e-43 | FFCP PHASE1:Mm9::chr5:135442713..135442733,+#_275695f35b4f699d2f94fb170614f736 | p@chr5:135442713..135442733, + |
1.74e-43 | FFCP PHASE2:Mm9::chr5:135442713..135442733,+#_275695f35b4f699d2f94fb170614f736 | p@chr5:135442713..135442733, + |
2.14e-43 | FFCP PHASE2:Mm9::chr2:38781010..38781017,+#_20cd4a444eba5e82e8fdb8191284f212 | p@chr2:38781010..38781017, + |
2.14e-43 | FFCP PHASE1:Mm9::chr2:38781010..38781017,+#_20cd4a444eba5e82e8fdb8191284f212 | p@chr2:38781010..38781017, + |
1.22e-42 | FFCP PHASE2:Mm9::chr10:80565428..80565433,+#_c67d067ae6b275ebafe82afdd9c3979f | p@chr10:80565428..80565433, + |
1.22e-42 | FFCP PHASE1:Mm9::chr10:80565428..80565433,+#_c67d067ae6b275ebafe82afdd9c3979f | p@chr10:80565428..80565433, + |
2.27e-42 | FFCP PHASE1:Mm9::chr11:35759012..35759018,+#_9d16b62671a0b6ee9866a03d6fbe7763 | p@chr11:35759012..35759018, + |
2.27e-42 | FFCP PHASE2:Mm9::chr11:35759012..35759018,+#_9d16b62671a0b6ee9866a03d6fbe7763 | p@chr11:35759012..35759018, + |
2.91e-42 | FFCP PHASE2:Mm9::chr18:66636209..66636215,-#_cc460b2210663dcf2426b3bca782d4fe | p@chr18:66636209..66636215, - |
2.91e-42 | FFCP PHASE1:Mm9::chr18:66636209..66636215,-#_cc460b2210663dcf2426b3bca782d4fe | p@chr18:66636209..66636215, - |
3.29e-42 | FFCP PHASE1:Mm9::chr16:78268076..78268083,-#_9998eb673505dd6a3d667b8de865ae89 | p@chr16:78268076..78268083, - |
3.29e-42 | FFCP PHASE2:Mm9::chr16:78268076..78268083,-#_9998eb673505dd6a3d667b8de865ae89 | p@chr16:78268076..78268083, - |
5.97e-41 | FFCP PHASE2:Mm9::chr1:88423123..88423134,-#_1d6e686a246b0de347198109b842e2aa | p@chr1:88423123..88423134, - |
5.97e-41 | FFCP PHASE1:Mm9::chr1:88423123..88423134,-#_1d6e686a246b0de347198109b842e2aa | p@chr1:88423123..88423134, - |
6.63e-41 | FFCP PHASE2:Mm9::chr16:30055801..30055806,+#_2989b78f9b5b30683c9c0da3a3bc738d | p@chr16:30055801..30055806, + |
6.63e-41 | FFCP PHASE1:Mm9::chr16:30055801..30055806,+#_2989b78f9b5b30683c9c0da3a3bc738d | p@chr16:30055801..30055806, + |
6.83e-41 | FFCP PHASE2:Mm9::chr3:89262676..89262696,-#_92da414940609762803f27476f57510f | p@chr3:89262676..89262696, - |
6.83e-41 | FFCP PHASE1:Mm9::chr3:89262676..89262696,-#_92da414940609762803f27476f57510f | p@chr3:89262676..89262696, - |
9.12e-41 | FFCP PHASE1:Mm9::chr7:19814309..19814320,+#_9c19f8b0a22797e98434eb50248aa858 | p@chr7:19814309..19814320, + |
9.12e-41 | FFCP PHASE2:Mm9::chr7:19814309..19814320,+#_9c19f8b0a22797e98434eb50248aa858 | p@chr7:19814309..19814320, + |
1.25e-40 | FFCP PHASE1:Mm9::chr16:91548532..91548555,-#_45dff7018f3b108974198310a194011f | p@chr16:91548532..91548555, - |
1.25e-40 | FFCP PHASE2:Mm9::chr16:91548532..91548555,-#_45dff7018f3b108974198310a194011f | p@chr16:91548532..91548555, - |
3.99e-40 | FFCP PHASE1:Mm9::chr15:77670701..77670706,+#_4a4bc1934ffc3f2dd8375d88dc24917d | p@chr15:77670701..77670706, + |
3.99e-40 | FFCP PHASE2:Mm9::chr15:77670701..77670706,+#_4a4bc1934ffc3f2dd8375d88dc24917d | p@chr15:77670701..77670706, + |
6.64e-40 | FFCP PHASE1:Mm9::chr3:126314780..126314810,-#_d0f77e693be56e5eb8d3a3b9004c32d1 | p@chr3:126314780..126314810, - |
6.64e-40 | FFCP PHASE2:Mm9::chr3:126314780..126314810,-#_d0f77e693be56e5eb8d3a3b9004c32d1 | p@chr3:126314780..126314810, - |
6.64e-40 | FFCP PHASE1:Mm9::chr5:32270354..32270364,-#_d0f77e693be56e5eb8d3a3b9004c32d1 | p@chr5:32270354..32270364, - |
6.64e-40 | FFCP PHASE2:Mm9::chr5:32270354..32270364,-#_d0f77e693be56e5eb8d3a3b9004c32d1 | p@chr5:32270354..32270364, - |
2.17e-39 | FFCP PHASE1:Mm9::chr12:111682896..111682907,+#_e07289f41c78e98929f7a36977fa0d58 | p@chr12:111682896..111682907, + |
2.17e-39 | FFCP PHASE2:Mm9::chr12:111682896..111682907,+#_e07289f41c78e98929f7a36977fa0d58 | p@chr12:111682896..111682907, + |
2.66e-39 | FFCP PHASE2:Mm9::chr1:90912298..90912303,+#_bcb0ef12a11eae5f4b0d2209a4bd0b34 | p3@1700067G17Rik |
2.66e-39 | FFCP PHASE1:Mm9::chr1:90912298..90912303,+#_bcb0ef12a11eae5f4b0d2209a4bd0b34 | p3@1700067G17Rik |
2.73e-39 | FFCP PHASE1:Mm9::chr2:84491058..84491102,+#_992d59fea71cbd47bf5e57e599cc49c5 | p@chr2:84491058..84491102, + |
2.73e-39 | FFCP PHASE2:Mm9::chr2:84491058..84491102,+#_992d59fea71cbd47bf5e57e599cc49c5 | p@chr2:84491058..84491102, + |
3.46e-39 | FFCP PHASE1:Mm9::chr15:100568814..100568821,-#_1f1b10aaff8d0c4a2454ea0d444b37af | p@chr15:100568814..100568821, - |
3.46e-39 | FFCP PHASE2:Mm9::chr15:100568814..100568821,-#_1f1b10aaff8d0c4a2454ea0d444b37af | p@chr15:100568814..100568821, - |
1.14e-38 | FFCP PHASE1:Mm9::chr2:167904248..167904260,+#_3af5dd4ceb0ed4adcfa47dd8a1533406 | p@chr2:167904248..167904260, + |
1.14e-38 | FFCP PHASE2:Mm9::chr2:167904248..167904260,+#_3af5dd4ceb0ed4adcfa47dd8a1533406 | p@chr2:167904248..167904260, + |
1.26e-38 | FFCP PHASE2:Mm9::chr10:19251573..19251584,+#_3ad046d75c56d81cdcc0ebf16df8144b | p@chr10:19251573..19251584, + |
1.26e-38 | FFCP PHASE1:Mm9::chr10:19251573..19251584,+#_3ad046d75c56d81cdcc0ebf16df8144b | p@chr10:19251573..19251584, + |
1.88e-38 | FFCP PHASE1:Mm9::chr9:66888952..66888964,+#_c9a58d650dcf00a3a2e13717f0fdb224 | p@chr9:66888952..66888964, + |
1.88e-38 | FFCP PHASE2:Mm9::chr9:66888952..66888964,+#_c9a58d650dcf00a3a2e13717f0fdb224 | p@chr9:66888952..66888964, + |
5.07e-38 | FFCP PHASE2:Mm9::chr1:36331417..36331462,+#_2d1b3fac92cc1f1a22f55ebbcaeb511b | p@chr1:36331417..36331462, + |
5.07e-38 | FFCP PHASE1:Mm9::chr1:36331417..36331462,+#_2d1b3fac92cc1f1a22f55ebbcaeb511b | p@chr1:36331417..36331462, + |
7.0e-37 | FFCP PHASE1:Mm9::chr15:83305098..83305104,+#_2668b6b21bd74f9012d7fbcdfa87142e | p@chr15:83305098..83305104, + |
7.0e-37 | FFCP PHASE2:Mm9::chr8:126155114..126155118,+#_2668b6b21bd74f9012d7fbcdfa87142e | p1@uc009nwl.1 |
7.0e-37 | FFCP PHASE1:Mm9::chr8:126155114..126155118,+#_2668b6b21bd74f9012d7fbcdfa87142e | p1@uc009nwl.1 |
7.0e-37 | FFCP PHASE2:Mm9::chr15:83305098..83305104,+#_2668b6b21bd74f9012d7fbcdfa87142e | p@chr15:83305098..83305104, + |
1.47e-36 | FFCP PHASE1:Mm9::chr7:20335303..20335317,+#_78acfe9601bcb187575582cbd063b0ff | p@chr7:20335303..20335317, + |
1.47e-36 | FFCP PHASE2:Mm9::chr7:20335303..20335317,+#_78acfe9601bcb187575582cbd063b0ff | p@chr7:20335303..20335317, + |
1.61e-36 | FFCP PHASE1:Mm9::chr5:135442349..135442362,-#_3b0b23e3b0ae6a656963e5a6f96bd93e | p@chr5:135442349..135442362, - |
1.61e-36 | FFCP PHASE2:Mm9::chr5:135442349..135442362,-#_3b0b23e3b0ae6a656963e5a6f96bd93e | p@chr5:135442349..135442362, - |
2.8e-36 | FFCP PHASE1:Mm9::chrX:96331285..96331289,-#_abe8129c850f1947dc3861bf34bf77be | p@chrX:96331285..96331289, - |
2.8e-36 | FFCP PHASE2:Mm9::chrX:96331285..96331289,-#_abe8129c850f1947dc3861bf34bf77be | p@chrX:96331285..96331289, - |
3.43e-36 | FFCP PHASE1:Mm9::chr4:62163210..62163216,-#_162d0e8b1bf259b48abd955dd8bc7563 | p3@Hdhd3 |
3.43e-36 | FFCP PHASE2:Mm9::chr5:145015979..145015991,-#_162d0e8b1bf259b48abd955dd8bc7563 | p@chr5:145015979..145015991, - |
3.43e-36 | FFCP PHASE2:Mm9::chr4:62163210..62163216,-#_162d0e8b1bf259b48abd955dd8bc7563 | p3@Hdhd3 |
3.43e-36 | FFCP PHASE1:Mm9::chr5:145015979..145015991,-#_162d0e8b1bf259b48abd955dd8bc7563 | p@chr5:145015979..145015991, - |
4.38e-36 | FFCP PHASE1:Mm9::chr7:29382208..29382215,+#_37beb8bc87e7caf32034b0f6a3eb02c3 | p@chr7:29382208..29382215, + |
4.38e-36 | FFCP PHASE2:Mm9::chr7:29382208..29382215,+#_37beb8bc87e7caf32034b0f6a3eb02c3 | p@chr7:29382208..29382215, + |
5.78e-36 | FFCP PHASE1:Mm9::chr14:73507116..73507118,+#_e8be2b4aa0a65058c510e685507dfd61 | p@chr14:73507116..73507118, + |
5.78e-36 | FFCP PHASE2:Mm9::chr14:73507116..73507118,+#_e8be2b4aa0a65058c510e685507dfd61 | p@chr14:73507116..73507118, + |
Property "Property value" (as page type) with input value "UBPROP:0000001 "Unilaminar epithelium that consists of a single layer of columnar cells.[AAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process., Property "Property value" (as page type) with input value "UBPROP:0000001 "Unilaminar epithelium that consists of a single layer of columnar cells.[CARO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process., Property "Property value" (as page type) with input value "UBPROP:0000001 "Unilaminar epithelium that consists of a single layer of columnar cells.[TAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.