UBERON:0000990: Difference between revisions
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{{UBERON | {{UBERON | ||
| | |alt_id=UBERON:FBbt_00004857-FMA_7160-MA_0000326-MIAA_0000305-WBbt_0005747-XAO_0000142-ZFA_0000632 | ||
|anatomical_img_id=FMA:7160 | |||
| | |||
|comment=This class was created automatically from a combination of ontologies | |comment=This class was created automatically from a combination of ontologies | ||
|created_by= | |created_by= | ||
| | |def="Anatomical system that has as its parts the organs concerned with reproduction." [Wikipedia:Reproductive_system] | ||
|derives_from= | |derives_from= | ||
|develops_from=UBERON:0000926 | |develops_from=UBERON:0000926 | ||
|disjoint_from=UBERON:0001004;;UBERON:0001007;;UBERON:0001008;;UBERON:0001009;;UBERON:0001016;;UBERON:0001033;;UBERON:0001434;;UBERON:0002204;;UBERON:0002294;;UBERON:0002330;;UBERON:0002390;;UBERON:0002405;;UBERON:0002416;;UBERON:0002423;;UBERON:0004456 | |||
|has_quality= | |has_quality= | ||
|id=UBERON:0000990 | |||
|is_a=UBERON:0000467 ;;UBERON:0004120 | |||
|is_obsolete= | |||
|located_in= | |located_in= | ||
|name=reproductive system | |||
|namespace=FANTOM | |||
|obo_creation_date= | |||
|part_of= | |part_of= | ||
|preceded_by= | |preceded_by= | ||
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl;;UBPROP:0000001 "Anatomical system which consists of organs and tissues associated with sexual reproduction of the organism.[AAO]" xsd:string | |||
|subset=functional_classification;;uberon_slim;;vertebrate_core | |||
|synonym="animal reproductive system" RELATED [BTO:0000081];;"genital system" RELATED [];;"genitalia" RELATED PLURAL [];;"Geschlechtsorgan" RELATED [BTO:0000081];;"organa genitalia" RELATED [BTO:0000081];;"reproductive tissue" RELATED [BTO:0000081];;"systemata genitalia" RELATED LATIN [Wikipedia:Reproductive_system] | |||
|union_of= | |||
|xref=AAO:0010258;;BILA:0000103;;BTO:0000081;;EFO:0000809;;EHDAA2:0001603;;EHDAA:5923;;EMAPA:17381;;EV:0100100;;FBbt:00004826;;FBbt:00004857;;FMA:7160;;GAID:363;;HAO:0000374;;HAO:0000895;;http://upload.wikimedia.org/wikipedia/commons/5/52/Penis.svg;;http://upload.wikimedia.org/wikipedia/commons/thumb/5/52/Penis.svg/200px-Penis.svg.png;;MA:0000326;;MIAA:0000305;;ncithesaurus:Reproductive_System;;OpenCyc:Mx4rvVja4ZwpEbGdrcN5Y29ycA;;SCTID:278875001;;TAO:0000632;;VHOG:0000182;;WBbt:0005747;;XAO:0000142;;ZFA:0000632 | |||
}} | }} |
Latest revision as of 17:13, 12 September 2014
Name: | reproductive system | ||
---|---|---|---|
Namespace: | FANTOM | ||
Definition: | "Anatomical system that has as its parts the organs concerned with reproduction." [Wikipedia:Reproductive_system] | ||
Xrefs: |
| ||
Synonyms: |
"animal reproductive system" RELATED [BTO:0000081] "genital system" RELATED [] "genitalia" RELATED PLURAL [] "Geschlechtsorgan" RELATED [BTO:0000081] "organa genitalia" RELATED [BTO:0000081] "reproductive tissue" RELATED [BTO:0000081] "systemata genitalia" RELATED LATIN [Wikipedia:Reproductive_system] | ||
Comments: | This class was created automatically from a combination of ontologies | ||
Alt_id: | UBERON:FBbt_00004857-FMA_7160-MA_0000326-MIAA_0000305-WBbt_0005747-XAO_0000142-ZFA_0000632 | ||
Subset: |
functional_classification uberon_slim vertebrate_core |
Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data
Parents
is_a: | UBERON:0000467(anatomical system),UBERON:0004120(mesoderm-derived structure) |
---|---|
disjoint_from: | UBERON:0001004(respiratory system),UBERON:0001007(digestive system),UBERON:0001008(renal system),UBERON:0001009(circulatory system),UBERON:0001016(nervous system),UBERON:0001033(gustatory system),UBERON:0001434(skeletal system),UBERON:0002204(musculoskeletal system),UBERON:0002294(biliary system),UBERON:0002330(exocrine system),UBERON:0002390(hematopoietic system),UBERON:0002405(immune system),UBERON:0002416(integumental system),UBERON:0002423(hepatobiliary system),UBERON:0004456(entire sense organ system) |
develops_from: | UBERON:0000926(mesoderm) |
Children
is a: | UBERON:0000079 (male reproductive system),UBERON:0000474 (female reproductive system) |
---|---|
disjoint from: | UBERON:0000949 (endocrine system) |
part of: | UBERON:0000991 (gonad),UBERON:0003133 (reproductive organ),UBERON:0003937 (sex gland),UBERON:0005156 (reproductive structure),UBERON:0005564 (gonad primordium) |
Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology
Human (Homo sapiens)
- 10013-101C4 (cervix, adult, pool1)
- 10020-101D2 (ovary, adult, pool1)
- 10021-101D3 (placenta, adult, pool1)
- 10022-101D4 (prostate, adult, pool1)
- 10026-101D8 (testis, adult, pool1)
- 10091-102C1
- 10092-102C2
- 10096-102C6 (testis, adult, pool2)
- 10100-102D1 (uterus, adult, pool1)
- 10196-103E7 (ductus deferens, adult)
... further results Mouse (Mus musculus)
- 10013-101C4 (cervix, adult, pool1)
- 10020-101D2 (ovary, adult, pool1)
- 10021-101D3 (placenta, adult, pool1)
- 10022-101D4 (prostate, adult, pool1)
- 10026-101D8 (testis, adult, pool1)
- 10091-102C1
- 10092-102C2
- 10096-102C6 (testis, adult, pool2)
- 10100-102D1 (uterus, adult, pool1)
- 10196-103E7 (ductus deferens, adult)
Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0000990 (reproductive system), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data
P-value | FFCP | Short description |
---|---|---|
1.07e-57 | FFCP PHASE2:Mm9::chr5:31271028..31271040,+#_1f07befdea0379c98dc83598e52bca0a | p1@Tcf23 |
1.07e-57 | FFCP PHASE1:Mm9::chr5:31271028..31271040,+#_1f07befdea0379c98dc83598e52bca0a | p1@Tcf23 |
2.67e-50 | FFCP PHASE1:Mm9::chr4:143998300..143998343,-#_c593d12baf8998b34f431ad5cc690a13 | p1@Pramef12 |
2.67e-50 | FFCP PHASE2:Mm9::chr4:143998300..143998343,-#_c593d12baf8998b34f431ad5cc690a13 | p1@Pramef12 |
3.52e-46 | FFCP PHASE2:Mm9::chr6:18059063..18059084,-#_b386b545415350d625271223619f6687 | p2@Asz1 |
3.52e-46 | FFCP PHASE1:Mm9::chr6:18059063..18059084,-#_b386b545415350d625271223619f6687 | p2@Asz1 |
1.54e-44 | FFCP PHASE1:Mm9::chr1:168168856..168168893,-#_db60389287bf842a3940c5d7b4aade12 | p1@Mael |
1.54e-44 | FFCP PHASE2:Mm9::chr1:168168856..168168893,-#_db60389287bf842a3940c5d7b4aade12 | p1@Mael |
1.04e-43 | FFCP PHASE2:Mm9::chr7:52741629..52741644,+#_941053d6b516c3f1285064b3311a3530 | p7@Tulp2 |
1.04e-43 | FFCP PHASE1:Mm9::chr7:52741629..52741644,+#_941053d6b516c3f1285064b3311a3530 | p7@Tulp2 |
1.59e-43 | FFCP PHASE1:Mm9::chr14:70829178..70829221,-#_96cf87ac8b0a2d36fa3d2828b5b26463 | p1@Piwil2 |
1.59e-43 | FFCP PHASE2:Mm9::chr14:70829178..70829221,-#_96cf87ac8b0a2d36fa3d2828b5b26463 | p1@Piwil2 |
6.16e-43 | FFCP PHASE2:Mm9::chr3:40512838..40512859,+#_41a1140d4d1636c525b8d9f999d9101c | p2@Slc25a31 |
6.16e-43 | FFCP PHASE1:Mm9::chr3:54985946..54985981,+#_41a1140d4d1636c525b8d9f999d9101c | p1@Sohlh2 |
6.16e-43 | FFCP PHASE2:Mm9::chr3:54985946..54985981,+#_41a1140d4d1636c525b8d9f999d9101c | p1@Sohlh2 |
6.16e-43 | FFCP PHASE1:Mm9::chr3:40512838..40512859,+#_41a1140d4d1636c525b8d9f999d9101c | p2@Slc25a31 |
6.47e-43 | FFCP PHASE2:Mm9::chr2:148615085..148615142,+#_9415685488e6554784d06926a6acd13a | p1@Cst12 |
6.47e-43 | FFCP PHASE1:Mm9::chr2:148615085..148615142,+#_9415685488e6554784d06926a6acd13a | p1@Cst12 |
6.69e-43 | FFCP PHASE2:Mm9::chr12:31775417..31775434,-#_71f2164e8d3a3229e0196db965177e51 | p@chr12:31775417..31775434, - |
6.69e-43 | FFCP PHASE1:Mm9::chr12:31775417..31775434,-#_71f2164e8d3a3229e0196db965177e51 | p@chr12:31775417..31775434, - |
7.14e-43 | FFCP PHASE1:Mm9::chr6:18059038..18059062,-#_421aff42b8be4c62cc814531e3760171 | p1@Asz1 |
7.14e-43 | FFCP PHASE2:Mm9::chr6:18059038..18059062,-#_421aff42b8be4c62cc814531e3760171 | p1@Asz1 |
3.8e-42 | FFCP PHASE1:Mm9::chr7:109015811..109015852,-#_b92f67d95f8858b09af7e11e3c70b215 | p6@Folr1 |
3.8e-42 | FFCP PHASE2:Mm9::chr7:109015811..109015852,-#_b92f67d95f8858b09af7e11e3c70b215 | p6@Folr1 |
2.08e-41 | FFCP PHASE1:Mm9::chr17:50432917..50432931,-#_f892c3012fc3c2b5d3cf0122aa69b787 | p1@Dazl |
2.08e-41 | FFCP PHASE2:Mm9::chr17:50432917..50432931,-#_f892c3012fc3c2b5d3cf0122aa69b787 | p1@Dazl |
2.8e-41 | FFCP PHASE2:Mm9::chr7:104599826..104599841,+#_262c23f6e08ab23f41f189aae0787954 | p2@Kctd14 |
2.8e-41 | FFCP PHASE1:Mm9::chr7:104599826..104599841,+#_262c23f6e08ab23f41f189aae0787954 | p2@Kctd14 |
3.43e-41 | FFCP PHASE1:Mm9::chr3:107746281..107746297,-#_7fa0ba09303f0c582cc845b5c0d12aa5 | p5@Gstm6 |
3.43e-41 | FFCP PHASE2:Mm9::chr3:107746281..107746297,-#_7fa0ba09303f0c582cc845b5c0d12aa5 | p5@Gstm6 |
5.46e-41 | FFCP PHASE2:Mm9::chr15:88813324..88813392,+#_37a828884baee01d6e037f04b941dff8 | p1@Mov10l1 |
5.46e-41 | FFCP PHASE1:Mm9::chr15:88813324..88813392,+#_37a828884baee01d6e037f04b941dff8 | p1@Mov10l1 |
1.3e-40 | FFCP PHASE1:Mm9::chr3:102740016..102740030,-#_5bfda84208ed8bcca2d4ed4c03253130 | p1@Sycp1 |
1.3e-40 | FFCP PHASE2:Mm9::chr3:102740016..102740030,-#_5bfda84208ed8bcca2d4ed4c03253130 | p1@Sycp1 |
2.45e-40 | FFCP PHASE1:Mm9::chr6:49345558..49345593,+#_b8b79476f89cafee5d8cd148f466b4e4 | p2@Stk31 |
2.45e-40 | FFCP PHASE2:Mm9::chr6:49345558..49345593,+#_b8b79476f89cafee5d8cd148f466b4e4 | p2@Stk31 |
2.68e-40 | FFCP PHASE2:Mm9::chrX:98989738..98989756,-#_49c4cd4c03f83befb1be5fbb1c18b206 | p@chrX:98989738..98989756, - |
2.68e-40 | FFCP PHASE1:Mm9::chrX:98989738..98989756,-#_49c4cd4c03f83befb1be5fbb1c18b206 | p@chrX:98989738..98989756, - |
3.95e-40 | FFCP PHASE2:Mm9::chr7:52741649..52741686,+#_e2b037bf8634ad4673f1489b080bca58 | p3@Tulp2 |
3.95e-40 | FFCP PHASE1:Mm9::chr7:52741649..52741686,+#_e2b037bf8634ad4673f1489b080bca58 | p3@Tulp2 |
6.39e-40 | FFCP PHASE1:Mm9::chrX:135868376..135868409,+#_d85279b4901309eff9b85e6628dc2436 | p1@Trap1a |
6.39e-40 | FFCP PHASE2:Mm9::chrX:135868376..135868409,+#_d85279b4901309eff9b85e6628dc2436 | p1@Trap1a |
6.53e-40 | FFCP PHASE1:Mm9::chrX:35232004..35232025,-#_b3853a5350e5561fa31b2e5fc0030ade | p@chrX:35232004..35232025, - |
6.53e-40 | FFCP PHASE2:Mm9::chrX:35232004..35232025,-#_b3853a5350e5561fa31b2e5fc0030ade | p@chrX:35232004..35232025, - |
6.63e-40 | FFCP PHASE1:Mm9::chr17:28644343..28644394,-#_d6743ba4a011f15c2218f1d95d777230 | p3@Fkbp5 |
6.63e-40 | FFCP PHASE2:Mm9::chr17:28644343..28644394,-#_d6743ba4a011f15c2218f1d95d777230 | p3@Fkbp5 |
6.93e-40 | FFCP PHASE2:Mm9::chr15:102275818..102275834,+#_b0383fc6cafc8784ea32c78d9e42b3f0 | p1@Amhr2 |
6.93e-40 | FFCP PHASE1:Mm9::chr15:102275818..102275834,+#_b0383fc6cafc8784ea32c78d9e42b3f0 | p1@Amhr2 |
7.7e-40 | FFCP PHASE2:Mm9::chr15:102277099..102277126,+#_6519d0937be0899e1735509a8c74211a | p@chr15:102277099..102277126, + |
7.7e-40 | FFCP PHASE1:Mm9::chr15:102277099..102277126,+#_6519d0937be0899e1735509a8c74211a | p@chr15:102277099..102277126, + |
1.04e-39 | FFCP PHASE1:Mm9::chr11:100939677..100939722,+#_00ffcbab2ae98ec0499480f979e9c845 | p1@Hsd17b1 |
1.04e-39 | FFCP PHASE2:Mm9::chr11:100939677..100939722,+#_00ffcbab2ae98ec0499480f979e9c845 | p1@Hsd17b1 |
1.17e-39 | FFCP PHASE2:Mm9::chr4:62295167..62295182,+#_0ceebef527c1c25e113cb1f7a7e58ef2 | p22@Rgs3 |
1.17e-39 | FFCP PHASE1:Mm9::chr2:148660852..148660861,+#_0ceebef527c1c25e113cb1f7a7e58ef2 | p3@Cst9 |
1.17e-39 | FFCP PHASE2:Mm9::chr2:148660852..148660861,+#_0ceebef527c1c25e113cb1f7a7e58ef2 | p3@Cst9 |
1.17e-39 | FFCP PHASE1:Mm9::chr5:31270977..31270988,+#_0ceebef527c1c25e113cb1f7a7e58ef2 | p3@Tcf23 |
1.17e-39 | FFCP PHASE1:Mm9::chr4:62295167..62295182,+#_0ceebef527c1c25e113cb1f7a7e58ef2 | p22@Rgs3 |
1.17e-39 | FFCP PHASE2:Mm9::chr5:31270977..31270988,+#_0ceebef527c1c25e113cb1f7a7e58ef2 | p3@Tcf23 |
3.94e-39 | FFCP PHASE2:Mm9::chr5:135825867..135825910,-#_0d2058c1a140a4d8a1748fb59c3658c8 | p1@Fkbp6 |
3.94e-39 | FFCP PHASE2:Mm9::chr7:149469129..149469146,+#_0d2058c1a140a4d8a1748fb59c3658c8 | p@chr7:149469129..149469146, + |
3.94e-39 | FFCP PHASE1:Mm9::chr7:149469129..149469146,+#_0d2058c1a140a4d8a1748fb59c3658c8 | p@chr7:149469129..149469146, + |
3.94e-39 | FFCP PHASE1:Mm9::chr5:135825867..135825910,-#_0d2058c1a140a4d8a1748fb59c3658c8 | p1@Fkbp6 |
4.47e-39 | FFCP PHASE1:Mm9::chr7:147143936..147143939,-#_2dbabf6396d0d823db9a9c6ac81a0fc0 | p1@Mir202 |
4.47e-39 | FFCP PHASE2:Mm9::chr7:147143936..147143939,-#_2dbabf6396d0d823db9a9c6ac81a0fc0 | p1@Mir202 |
7.41e-39 | FFCP PHASE1:Mm9::chr11:87218551..87218615,+#_8d672969072aa42abe675dffae706c31 | p1@Tex14 |
7.41e-39 | FFCP PHASE2:Mm9::chr11:87218551..87218615,+#_8d672969072aa42abe675dffae706c31 | p1@Tex14 |
1.02e-38 | FFCP PHASE2:Mm9::chr17:32171438..32171468,-#_02f3c8ef503960fed5eb2ebc0aea397e | p1@Hsf2bp |
1.02e-38 | FFCP PHASE1:Mm9::chr17:32171438..32171468,-#_02f3c8ef503960fed5eb2ebc0aea397e | p1@Hsf2bp |
1.58e-38 | FFCP PHASE2:Mm9::chr3:95363593..95363613,+#_15b9c22e55dbd743cd3ab0cca0631859 | p1@Hormad1 |
1.58e-38 | FFCP PHASE1:Mm9::chr3:95363593..95363613,+#_15b9c22e55dbd743cd3ab0cca0631859 | p1@Hormad1 |
1.68e-38 | FFCP PHASE2:Mm9::chr13:24026303..24026308,+#_c5d8a54f9245319a227f8e8f1b2be070 | p1@Hist1h2aa |
1.68e-38 | FFCP PHASE1:Mm9::chr13:24026303..24026308,+#_c5d8a54f9245319a227f8e8f1b2be070 | p1@Hist1h2aa |
4.6e-38 | FFCP PHASE1:Mm9::chr2:104966510..104966538,-#_66a8af172dcc5ce684341bc5b4cc9dc3 | p2@ENSMUST00000174870 |
4.6e-38 | FFCP PHASE2:Mm9::chr2:104966510..104966538,-#_66a8af172dcc5ce684341bc5b4cc9dc3 | p2@ENSMUST00000174870 |
6.95e-38 | FFCP PHASE2:Mm9::chr9:50369387..50369406,-#_e45c8bc7bfd4b4b60b4a828761b88b98 | p1@Tex12 |
6.95e-38 | FFCP PHASE1:Mm9::chr9:50369387..50369406,-#_e45c8bc7bfd4b4b60b4a828761b88b98 | p1@Tex12 |
9.65e-38 | FFCP PHASE1:Mm9::chr18:47081451..47081490,+#_27d33738d8fe6cb1cd2804446e5e3350 | p1@Gm949 |
9.65e-38 | FFCP PHASE2:Mm9::chr18:47081451..47081490,+#_27d33738d8fe6cb1cd2804446e5e3350 | p1@Gm949 |
1.34e-37 | FFCP PHASE1:Mm9::chr19:40968642..40968653,+#_858733e7f5da03254a432e7456ad06fb | p@chr19:40968642..40968653, + |
1.34e-37 | FFCP PHASE2:Mm9::chr19:40968642..40968653,+#_858733e7f5da03254a432e7456ad06fb | p@chr19:40968642..40968653, + |
2.5e-37 | FFCP PHASE1:Mm9::chr3:107746250..107746266,-#_5a8b44d18aab38a54ab06b473137edb4 | p4@Gstm6 |
2.5e-37 | FFCP PHASE2:Mm9::chr3:107746250..107746266,-#_5a8b44d18aab38a54ab06b473137edb4 | p4@Gstm6 |
2.57e-37 | FFCP PHASE1:Mm9::chr1:36739960..36739999,-#_90cd6b648f6147419cab1ded8fc4ecbb | p1@Fam178b |
2.57e-37 | FFCP PHASE1:Mm9::chr6:125236033..125236068,-#_90cd6b648f6147419cab1ded8fc4ecbb | p1@Tuba3a, p2@Tuba3b |
2.57e-37 | FFCP PHASE1:Mm9::chr6:145564529..145564546,+#_90cd6b648f6147419cab1ded8fc4ecbb | p1@Tuba3b |
2.57e-37 | FFCP PHASE2:Mm9::chr6:145564529..145564546,+#_90cd6b648f6147419cab1ded8fc4ecbb | p1@Tuba3b |
2.57e-37 | FFCP PHASE2:Mm9::chr6:125236033..125236068,-#_90cd6b648f6147419cab1ded8fc4ecbb | p1@Tuba3a, p2@Tuba3b |
2.57e-37 | FFCP PHASE2:Mm9::chr1:36739960..36739999,-#_90cd6b648f6147419cab1ded8fc4ecbb | p1@Fam178b |
3.24e-37 | FFCP PHASE2:Mm9::chr7:20074394..20074416,+#_47ab54b2ddc5c9a778a6eabc3932babb | p1@Exoc3l2 |
3.24e-37 | FFCP PHASE1:Mm9::chr7:20074394..20074416,+#_47ab54b2ddc5c9a778a6eabc3932babb | p1@Exoc3l2 |
6.46e-37 | FFCP PHASE2:Mm9::chr7:36322696..36322738,-#_fa723a3e1b75e29d35c6b0a76c611c6c | p1@Tdrd12 |
6.46e-37 | FFCP PHASE1:Mm9::chr7:36322696..36322738,-#_fa723a3e1b75e29d35c6b0a76c611c6c | p1@Tdrd12 |
6.93e-37 | FFCP PHASE1:Mm9::chrX:103416484..103416508,-#_8075417bb9aa1f545102ebe818047230 | p4@Taf9b |
6.93e-37 | FFCP PHASE2:Mm9::chrX:103416484..103416508,-#_8075417bb9aa1f545102ebe818047230 | p4@Taf9b |
1.25e-36 | FFCP PHASE2:Mm9::chr13:64190487..64190500,-#_dcbdfada163dd1e8111705634ab55f5b | p3@Hsd17b3 |
1.25e-36 | FFCP PHASE2:Mm9::chr7:20074432..20074443,+#_dcbdfada163dd1e8111705634ab55f5b | p2@Exoc3l2 |
1.25e-36 | FFCP PHASE1:Mm9::chr7:20074432..20074443,+#_dcbdfada163dd1e8111705634ab55f5b | p2@Exoc3l2 |
1.25e-36 | FFCP PHASE1:Mm9::chr13:64190487..64190500,-#_dcbdfada163dd1e8111705634ab55f5b | p3@Hsd17b3 |
1.34e-36 | FFCP PHASE2:Mm9::chrX:50788166..50788192,+#_a0b7a452e7b76bda7c68b99e934c9475 | p1@Etd |
1.34e-36 | FFCP PHASE1:Mm9::chrX:50788166..50788192,+#_a0b7a452e7b76bda7c68b99e934c9475 | p1@Etd |
Property "Property value" (as page type) with input value "UBPROP:0000001 "Anatomical system which consists of organs and tissues associated with sexual reproduction of the organism.[AAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.