UBERON:0000074: Difference between revisions
From FANTOM5_SSTAR
(Created page with "{{UBERON
|id=UBERON:0000074
|name=renal glomerulus
|namespace=
|def="A capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangiu...") |
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{{UBERON | {{UBERON | ||
|alt_id= | |alt_id= | ||
| | |comment=ZFA - The multi-tissue structure where the glomerular basement membrane supported by mesonephric podocytes filters blood from the glomerular capillaries. TODO - split glomerulus and glomerular tuft? DONE. GUDMAP: 'Together, the Bowman遯カ蜀ア capsule and the glomerulus comprise the definitive renal corpuscle.' - here the glomerulus is part of the capsule? | ||
|created_by=Melissa Haendel | |created_by=Melissa Haendel | ||
| | |def="A capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the vertebrate kidney[GO]." [MP:0005325, Wikipedia:Glomerulus] | ||
|derives_from= | |derives_from= | ||
|develops_from= | |develops_from=UBERON:0005749 | ||
|disjoint_from= | |||
|has_quality= | |has_quality= | ||
|id=UBERON:0000074 | |||
|is_a=UBERON:0000064 ;;UBERON:0004120 ;;UBERON:0006554 | |||
|is_obsolete= | |||
|located_in= | |located_in= | ||
|name=renal glomerulus | |||
|namespace=FANTOM | |||
|obo_creation_date=2009-06-18T09:26:37Z | |||
|part_of=UBERON:0001229 | |part_of=UBERON:0001229 | ||
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl-to-uberon | |preceded_by= | ||
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl-to-uberon.owl;;IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl;;UBPROP:0000001 "A tuft of capillaries found in a Bowman's capsule in which waste products are filtered from the blood and urine formation is initiated.[AAO]" xsd:string | |||
|subset=vertebrate_core | |||
|synonym="glomerular capillary tuft" RELATED [ZFA:0001288];;"glomerular tuft" RELATED [];;"glomerulus" BROAD [];;"glomerulus renis" RELATED LATIN [Wikipedia:Glomerulus];;"malphigian glomerulus" RELATED [BTO:0000530];;"renal corpuscle" RELATED [] | |||
|union_of= | |||
|xref=AAO:0010388;;BTO:0000530;;EFO:0003667;;EV:0100386;;FMA:15624;;http://upload.wikimedia.org/wikipedia/commons/2/22/Renal_corpuscle.svg;;http://upload.wikimedia.org/wikipedia/commons/3/30/Gray1130.svg;;http://upload.wikimedia.org/wikipedia/commons/thumb/3/30/Gray1130.svg/200px-Gray1130.svg.png;;MA:0001657;;MESH:A.05.810.453.736.520;;ncithesaurus:Glomerulus;;TAO:0001288;;XAO:0000146;;ZFA:0001288 | |||
}} | }} |
Latest revision as of 17:05, 12 September 2014
Name: | renal glomerulus | ||
---|---|---|---|
Namespace: | FANTOM | ||
Definition: | "A capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the vertebrate kidney[GO]." [MP:0005325, Wikipedia:Glomerulus] | ||
Xrefs: |
| ||
Synonyms: |
"glomerular capillary tuft" RELATED [ZFA:0001288] "glomerular tuft" RELATED [] "glomerulus" BROAD [] "glomerulus renis" RELATED LATIN [Wikipedia:Glomerulus] "malphigian glomerulus" RELATED [BTO:0000530] "renal corpuscle" RELATED [] | ||
Comments: | ZFA - The multi-tissue structure where the glomerular basement membrane supported by mesonephric podocytes filters blood from the glomerular capillaries. TODO - split glomerulus and glomerular tuft? DONE. GUDMAP: 'Together, the Bowman遯カ蜀ア capsule and the glomerulus comprise the definitive renal corpuscle.' - here the glomerulus is part of the capsule? | ||
Subset: | vertebrate_core | ||
Created by: | Melissa Haendel | ||
Creation date: | 2009-06-18T09:26:37Z |
Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data
Parents
is_a: | UBERON:0000064(organ part),UBERON:0004120(mesoderm-derived structure),UBERON:0006554(urinary system structure) |
---|---|
develops_from: | UBERON:0005749(glomerular tuft) |
part_of: | UBERON:0001229(renal corpuscle) |
Children
part of: | CL:0002188 (glomerular endothelial cell),UBERON:0002319 (mesangium),CL:1000746 (glomerular cell) |
---|
Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology
Human (Homo sapiens)
- 11514-119H2 (Renal Glomerular Endothelial Cells, donor1)
- 11518-119H6 (Renal Mesangial Cells, donor1)
- 11590-120G6 (Alveolar Epithelial Cells, donor2)
- 11594-120H1 (Renal Glomerular Endothelial Cells, donor2)
- 11598-120H5 (Renal Mesangial Cells, donor2)
- 11675-122H1 (Renal Glomerular Endothelial Cells, donor3)
- 11679-122H5 (Renal Mesangial Cells, donor3)
- 11783-124B1 (Renal Glomerular Endothelial Cells, donor4)
Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0000074 (renal glomerulus), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data
P-value | FFCP | Short description |
---|---|---|
6.87e-64 | FFCP PHASE2:Hg19::chr2:120409486..120409492,+#_4d7bb32267b0b9fb2a444b7a94d53bd5 | p@chr2:120409486..120409492, + |
6.87e-64 | FFCP PHASE1:Hg19::chr2:120409486..120409492,+#_4d7bb32267b0b9fb2a444b7a94d53bd5 | p@chr2:120409486..120409492, + |
9.62e-40 | FFCP PHASE1:Hg19::chr1:94713418..94713436,+#_97659a7127319b72d9dbe5a7f616805e | p1@ENST00000413103 |
9.62e-40 | FFCP PHASE2:Hg19::chr1:94713418..94713436,+#_97659a7127319b72d9dbe5a7f616805e | p1@ENST00000413103 |
1.16e-36 | FFCP PHASE1:Hg19::chr17:79426453..79426462,+#_4a9985f04e03bfa4e388e4a2c72a694a | p@chr17:79426453..79426462, + |
1.16e-36 | FFCP PHASE2:Hg19::chr17:79426453..79426462,+#_4a9985f04e03bfa4e388e4a2c72a694a | p@chr17:79426453..79426462, + |
1.31e-36 | FFCP PHASE2:Hg19::chr8:77557753..77557755,-#_71d555d3b0dee30fe005fea652dc57e6 | p@chr8:77557753..77557755, - |
1.31e-36 | FFCP PHASE1:Hg19::chr8:77557753..77557755,-#_71d555d3b0dee30fe005fea652dc57e6 | p@chr8:77557753..77557755, - |
5.58e-32 | FFCP PHASE1:Hg19::chr1:32042764..32042776,+#_30edbc2fbcd503ad7e75d1193e96a5ef | p6@TINAGL1 |
5.58e-32 | FFCP PHASE2:Hg19::chr1:32042764..32042776,+#_30edbc2fbcd503ad7e75d1193e96a5ef | p6@TINAGL1 |
1.53e-30 | FFCP PHASE2:Hg19::chr15:91416076..91416089,+#_18088851ade55b5298aa2c0484dcca37 | p9@FURIN |
1.53e-30 | FFCP PHASE1:Hg19::chr15:91416076..91416089,+#_18088851ade55b5298aa2c0484dcca37 | p9@FURIN |
3.83e-30 | FFCP PHASE2:Hg19::chr20:6034598..6034603,-#_67acd62f283b10e4a12b18d74e0c8ee0 | p7@LRRN4 |
3.83e-30 | FFCP PHASE1:Hg19::chr20:6034598..6034603,-#_67acd62f283b10e4a12b18d74e0c8ee0 | p7@LRRN4 |
1.78e-29 | FFCP PHASE1:Hg19::chr1:42777312..42777314,+#_733f9dc9e8b9f2d83638ada760f03d76 | p@chr1:42777312..42777314, + |
1.78e-29 | FFCP PHASE1:Hg19::chr2:26700984..26700993,-#_733f9dc9e8b9f2d83638ada760f03d76 | p7@OTOF |
1.78e-29 | FFCP PHASE1:Hg19::chr6:18225523..18225534,-#_733f9dc9e8b9f2d83638ada760f03d76 | p@chr6:18225523..18225534, - |
1.78e-29 | FFCP PHASE1:Hg19::chr2:26700331..26700340,-#_733f9dc9e8b9f2d83638ada760f03d76 | p@chr2:26700331..26700340, - |
1.78e-29 | FFCP PHASE2:Hg19::chr22:47030082..47030087,+#_733f9dc9e8b9f2d83638ada760f03d76 | p@chr22:47030082..47030087, + |
1.78e-29 | FFCP PHASE2:Hg19::chr1:42777312..42777314,+#_733f9dc9e8b9f2d83638ada760f03d76 | p@chr1:42777312..42777314, + |
1.78e-29 | FFCP PHASE1:Hg19::chr22:47030082..47030087,+#_733f9dc9e8b9f2d83638ada760f03d76 | p@chr22:47030082..47030087, + |
1.78e-29 | FFCP PHASE2:Hg19::chr2:26700984..26700993,-#_733f9dc9e8b9f2d83638ada760f03d76 | p7@OTOF |
1.78e-29 | FFCP PHASE2:Hg19::chr6:18225523..18225534,-#_733f9dc9e8b9f2d83638ada760f03d76 | p@chr6:18225523..18225534, - |
1.78e-29 | FFCP PHASE2:Hg19::chr2:26700331..26700340,-#_733f9dc9e8b9f2d83638ada760f03d76 | p@chr2:26700331..26700340, - |
7.96e-27 | FFCP PHASE1:Hg19::chr10:3477893..3477912,-#_a2916e13c10b3c76d9082e1de3869b8f | p@chr10:3477893..3477912, - |
7.96e-27 | FFCP PHASE2:Hg19::chr10:3477893..3477912,-#_a2916e13c10b3c76d9082e1de3869b8f | p@chr10:3477893..3477912, - |
6.29e-26 | FFCP PHASE2:Hg19::chr1:172926077..172926120,-#_0c95fa40010870ab14a9e92fbbef39e3 | p@chr1:172926077..172926120, - |
6.29e-26 | FFCP PHASE1:Hg19::chr1:172926077..172926120,-#_0c95fa40010870ab14a9e92fbbef39e3 | p@chr1:172926077..172926120, - |
6.32e-26 | FFCP PHASE1:Hg19::chrX:128782722..128782738,-#_87b777cedf25092d016c0552504ed12c | p5@APLN |
6.32e-26 | FFCP PHASE2:Hg19::chrX:128782722..128782738,-#_87b777cedf25092d016c0552504ed12c | p5@APLN |
9.89e-26 | FFCP PHASE1:Hg19::chr2:693380..693398,+#_6115a428bb677e4243c3a9f2f9d6f4c1 | p@chr2:693380..693398, + |
9.89e-26 | FFCP PHASE2:Hg19::chr2:693380..693398,+#_6115a428bb677e4243c3a9f2f9d6f4c1 | p@chr2:693380..693398, + |
1.28e-23 | FFCP PHASE2:Hg19::chr2:133426030..133426041,-#_3596fccbe3f03a8ebc4ba3cea360941a | p@chr2:133426030..133426041, - |
1.28e-23 | FFCP PHASE1:Hg19::chr6:84849252..84849259,+#_3596fccbe3f03a8ebc4ba3cea360941a | p@chr6:84849252..84849259, + |
1.28e-23 | FFCP PHASE1:Hg19::chr2:133426030..133426041,-#_3596fccbe3f03a8ebc4ba3cea360941a | p@chr2:133426030..133426041, - |
1.28e-23 | FFCP PHASE2:Hg19::chr6:84849252..84849259,+#_3596fccbe3f03a8ebc4ba3cea360941a | p@chr6:84849252..84849259, + |
1.44e-23 | FFCP PHASE1:Hg19::chr1:51791596..51791607,-#_5a11f540c09519e76589bbea4a0d900e | p23@TTC39A |
1.44e-23 | FFCP PHASE1:Hg19::chr7:28998254..28998261,-#_5a11f540c09519e76589bbea4a0d900e | p10@TRIL |
1.44e-23 | FFCP PHASE2:Hg19::chr1:51791596..51791607,-#_5a11f540c09519e76589bbea4a0d900e | p23@TTC39A |
1.44e-23 | FFCP PHASE2:Hg19::chr7:28998254..28998261,-#_5a11f540c09519e76589bbea4a0d900e | p10@TRIL |
1.61e-23 | FFCP PHASE1:Hg19::chr7:4051097..4051112,+#_c69b8f50c48e31ab6dd3a1d32b2060d8 | p@chr7:4051097..4051112, + |
1.61e-23 | FFCP PHASE1:Hg19::chr15:85403302..85403304,+#_c69b8f50c48e31ab6dd3a1d32b2060d8 | p@chr15:85403302..85403304, + |
1.61e-23 | FFCP PHASE2:Hg19::chr7:4051097..4051112,+#_c69b8f50c48e31ab6dd3a1d32b2060d8 | p@chr7:4051097..4051112, + |
1.61e-23 | FFCP PHASE2:Hg19::chr15:85403302..85403304,+#_c69b8f50c48e31ab6dd3a1d32b2060d8 | p@chr15:85403302..85403304, + |
1.8e-23 | FFCP PHASE1:Hg19::chr16:2141529..2141537,+#_a0324e5c27913e3e5ccaf2be03ebcfce | p@chr16:2141529..2141537, + |
1.8e-23 | FFCP PHASE2:Hg19::chr16:2141529..2141537,+#_a0324e5c27913e3e5ccaf2be03ebcfce | p@chr16:2141529..2141537, + |
2.92e-22 | FFCP PHASE2:Hg19::chr5:74244100..74244117,+#_0b956ebd98481844f07d4d38dd9183ac | p@chr5:74244100..74244117, + |
2.92e-22 | FFCP PHASE1:Hg19::chr5:74244100..74244117,+#_0b956ebd98481844f07d4d38dd9183ac | p@chr5:74244100..74244117, + |
5.69e-22 | FFCP PHASE1:Hg19::chr5:148651758..148651769,-#_1f987939d8ad71f759f0735c39eeb874 | p@chr5:148651758..148651769, - |
5.69e-22 | FFCP PHASE2:Hg19::chr5:148651758..148651769,-#_1f987939d8ad71f759f0735c39eeb874 | p@chr5:148651758..148651769, - |
2.9e-21 | FFCP PHASE2:Hg19::chr16:86768403..86768437,+#_ee2df898c8d0a199de08eb57871e65b9 | p@chr16:86768403..86768437, + |
2.9e-21 | FFCP PHASE1:Hg19::chr16:86768403..86768437,+#_ee2df898c8d0a199de08eb57871e65b9 | p@chr16:86768403..86768437, + |
4.78e-21 | FFCP PHASE2:Hg19::chr17:2076002..2076026,-#_576a0f2ec94151fab3108586ea9e5184 | p@chr17:2076002..2076026, - |
4.78e-21 | FFCP PHASE1:Hg19::chr17:2076002..2076026,-#_576a0f2ec94151fab3108586ea9e5184 | p@chr17:2076002..2076026, - |
1.26e-20 | FFCP PHASE1:Hg19::chr1:32712897..32712909,+#_92f3ba778dd5ee2c8f4c475a7b022437 | p3@FAM167B |
1.26e-20 | FFCP PHASE2:Hg19::chr1:32712897..32712909,+#_92f3ba778dd5ee2c8f4c475a7b022437 | p3@FAM167B |
2.32e-20 | FFCP PHASE2:Hg19::chr11:124628392..124628427,-#_d106ab53c243d5e82e77ba322565d5d9 | p@chr11:124628392..124628427, - |
2.32e-20 | FFCP PHASE1:Hg19::chr11:124628392..124628427,-#_d106ab53c243d5e82e77ba322565d5d9 | p@chr11:124628392..124628427, - |
3.42e-20 | FFCP PHASE2:Hg19::chr3:98591021..98591026,-#_24e37e2c0cceba8385f7b4670d941993 | p1@ENST00000487339 |
3.42e-20 | FFCP PHASE1:Hg19::chr3:98591021..98591026,-#_24e37e2c0cceba8385f7b4670d941993 | p1@ENST00000487339 |
3.44e-20 | FFCP PHASE1:Hg19::chr19:47231340..47231383,-#_c6867c006a2cf50541037386f72e1cd2 | p@chr19:47231340..47231383, - |
3.44e-20 | FFCP PHASE2:Hg19::chr19:47231340..47231383,-#_c6867c006a2cf50541037386f72e1cd2 | p@chr19:47231340..47231383, - |
3.58e-20 | FFCP PHASE1:Hg19::chr19:1826957..1826984,-#_fe561ea1d4f590d60150e7d16136051c | p@chr19:1826957..1826984, - |
3.58e-20 | FFCP PHASE2:Hg19::chr19:1826957..1826984,-#_fe561ea1d4f590d60150e7d16136051c | p@chr19:1826957..1826984, - |
4.39e-20 | FFCP PHASE1:Hg19::chr4:38057595..38057624,-#_fd92ee6c214b52445766a94483f7e594 | p@chr4:38057595..38057624, - |
4.39e-20 | FFCP PHASE2:Hg19::chr4:38057595..38057624,-#_fd92ee6c214b52445766a94483f7e594 | p@chr4:38057595..38057624, - |
7.13e-20 | FFCP PHASE1:Hg19::chr2:133426106..133426117,-#_2d8d19251ba0293d9080956690525156 | p@chr2:133426106..133426117, - |
7.13e-20 | FFCP PHASE2:Hg19::chr2:133426106..133426117,-#_2d8d19251ba0293d9080956690525156 | p@chr2:133426106..133426117, - |
7.84e-20 | FFCP PHASE2:Hg19::chr9:35753821..35753835,-#_333ef571f59da48992ec5476937e15df | p@chr9:35753821..35753835, - |
7.84e-20 | FFCP PHASE1:Hg19::chr15:36653709..36653720,-#_333ef571f59da48992ec5476937e15df | p@chr15:36653709..36653720, - |
7.84e-20 | FFCP PHASE2:Hg19::chr15:36653709..36653720,-#_333ef571f59da48992ec5476937e15df | p@chr15:36653709..36653720, - |
7.84e-20 | FFCP PHASE1:Hg19::chr9:35753821..35753835,-#_333ef571f59da48992ec5476937e15df | p@chr9:35753821..35753835, - |
8.62e-20 | FFCP PHASE1:Hg19::chr4:145568170..145568180,-#_c510e71931ea3197e9eb2d52bc4ab041 | p@chr4:145568170..145568180, - |
8.62e-20 | FFCP PHASE2:Hg19::chr4:145568170..145568180,-#_c510e71931ea3197e9eb2d52bc4ab041 | p@chr4:145568170..145568180, - |
1.04e-19 | FFCP PHASE2:Hg19::chr19:38397228..38397266,-#_2c6ea6663e56382ce8aa86608b09866e | p1@WDR87 |
1.04e-19 | FFCP PHASE1:Hg19::chr19:38397228..38397266,-#_2c6ea6663e56382ce8aa86608b09866e | p1@WDR87 |
1.15e-19 | FFCP PHASE1:Hg19::chr14:91270270..91270281,-#_cfeadbad5e4c98a42b21b631a1b759be | p@chr14:91270270..91270281, - |
1.15e-19 | FFCP PHASE2:Hg19::chr14:91270270..91270281,-#_cfeadbad5e4c98a42b21b631a1b759be | p@chr14:91270270..91270281, - |
2.44e-19 | FFCP PHASE2:Hg19::chr12:52306196..52306215,+#_682c6ac922ea900a70c2691c8c7eb067 | p6@ACVRL1 |
2.44e-19 | FFCP PHASE1:Hg19::chr12:52306196..52306215,+#_682c6ac922ea900a70c2691c8c7eb067 | p6@ACVRL1 |
3.27e-19 | FFCP PHASE2:Hg19::chr3:43538305..43538325,-#_104da4dd9fdcb9be85ecb2ee263e2b05 | p@chr3:43538305..43538325, - |
3.27e-19 | FFCP PHASE1:Hg19::chr3:43538305..43538325,-#_104da4dd9fdcb9be85ecb2ee263e2b05 | p@chr3:43538305..43538325, - |
4.64e-19 | FFCP PHASE1:Hg19::chr17:171147..171161,+#_b49e28446bfa9eff58600698b6b65be5 | p@chr17:171147..171161, + |
4.64e-19 | FFCP PHASE2:Hg19::chr17:171147..171161,+#_b49e28446bfa9eff58600698b6b65be5 | p@chr17:171147..171161, + |
5.39e-19 | FFCP PHASE1:Hg19::chr1:22211913..22211920,+#_15a2fe930cb511c22d7f767f86f9a5f1 | p@chr1:22211913..22211920, + |
5.39e-19 | FFCP PHASE2:Hg19::chr1:22211913..22211920,+#_15a2fe930cb511c22d7f767f86f9a5f1 | p@chr1:22211913..22211920, + |
1.99e-18 | FFCP PHASE1:Hg19::chr7:27219833..27219845,-#_3704e2ce1e7130bd1c46bfb0e3718dcc | p7@HOXA10 |
1.99e-18 | FFCP PHASE2:Hg19::chr7:27219833..27219845,-#_3704e2ce1e7130bd1c46bfb0e3718dcc | p7@HOXA10 |
2.69e-18 | FFCP PHASE2:Hg19::chr1:32041957..32041990,+#_7be61c06df7fd3ca4ec7ff76b9141200 | p3@TINAGL1 |
2.69e-18 | FFCP PHASE1:Hg19::chr1:32041957..32041990,+#_7be61c06df7fd3ca4ec7ff76b9141200 | p3@TINAGL1 |
4.1e-18 | FFCP PHASE2:Hg19::chr6:132270228..132270243,-#_2fe4b0fcc4156832096f8130c2320380 | p17@CTGF |
4.1e-18 | FFCP PHASE1:Hg19::chr6:132270228..132270243,-#_2fe4b0fcc4156832096f8130c2320380 | p17@CTGF |
5.7e-18 | FFCP PHASE2:Hg19::chr11:940729..940745,+#_78b62f5748371434c91c898b09c8dca2 | p5@AP2A2 |
5.7e-18 | FFCP PHASE1:Hg19::chr11:940729..940745,+#_78b62f5748371434c91c898b09c8dca2 | p5@AP2A2 |
6.5e-18 | FFCP PHASE2:Hg19::chr19:42007093..42007107,-#_1606ac664f69b9e814bfd5c53bafc807 | p@chr19:42007093..42007107, - |
6.5e-18 | FFCP PHASE1:Hg19::chr19:42007093..42007107,-#_1606ac664f69b9e814bfd5c53bafc807 | p@chr19:42007093..42007107, - |
6.99e-18 | FFCP PHASE2:Hg19::chrX:128781853..128781866,-#_7f66d6c54689ffb4afcb079c0def1444 | p@chrX:128781853..128781866, - |
6.99e-18 | FFCP PHASE1:Hg19::chrX:128781853..128781866,-#_7f66d6c54689ffb4afcb079c0def1444 | p@chrX:128781853..128781866, - |
1.24e-17 | FFCP PHASE1:Hg19::chr16:86604624..86604648,+#_2a3816c46b6d9ddb4c80866bcc383355 | p@chr16:86604624..86604648, + |
1.24e-17 | FFCP PHASE2:Hg19::chr16:86604624..86604648,+#_2a3816c46b6d9ddb4c80866bcc383355 | p@chr16:86604624..86604648, + |
Property "Property value" (as page type) with input value "UBPROP:0000001 "A tuft of capillaries found in a Bowman's capsule in which waste products are filtered from the blood and urine formation is initiated.[AAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.