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|ontology_enrichment_disease=
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0009569!3.94e-11!66;UBERON:0005172!1.42e-10!49;UBERON:0005173!1.42e-10!49;UBERON:0002417!1.42e-10!49;UBERON:0000916!1.42e-10!49;UBERON:0002106!1.10e-09!6;UBERON:0004457!1.10e-09!6;UBERON:0000042!1.10e-09!6;UBERON:0004854!1.10e-09!6;UBERON:0009034!1.10e-09!6;UBERON:0002095!1.10e-09!6;UBERON:0004782!1.10e-09!6;UBERON:0003281!1.10e-09!6;UBERON:0009664!1.10e-09!6;UBERON:0002296!1.10e-09!6;UBERON:0005602!1.10e-09!6;UBERON:0001179!1.10e-09!6;UBERON:0006293!1.10e-09!6;UBERON:0001041!2.86e-09!80;UBERON:0005177!6.02e-08!79;UBERON:0003887!3.58e-07!10
|ontology_enrichment_uberon=UBERON:0009569!3.94e-11!66;UBERON:0005172!1.42e-10!49;UBERON:0005173!1.42e-10!49;UBERON:0002417!1.42e-10!49;UBERON:0000916!1.42e-10!49;UBERON:0002106!1.10e-09!6;UBERON:0004457!1.10e-09!6;UBERON:0000042!1.10e-09!6;UBERON:0004854!1.10e-09!6;UBERON:0009034!1.10e-09!6;UBERON:0002095!1.10e-09!6;UBERON:0004782!1.10e-09!6;UBERON:0003281!1.10e-09!6;UBERON:0009664!1.10e-09!6;UBERON:0002296!1.10e-09!6;UBERON:0005602!1.10e-09!6;UBERON:0001179!1.10e-09!6;UBERON:0006293!1.10e-09!6;UBERON:0001041!2.86e-09!80;UBERON:0005177!6.02e-08!79;UBERON:0003887!3.58e-07!10
|tfbs_overrepresentation_for_novel_motifs=0.2121,0.386572,0.183547,0.554666,0.403653,0.279466,0.798998,1.08451,0.367856,0.148944,0.340369,0.384124,0.188374,0.828885,0.23585,0,0.259755,0.633675,0.160901,0.438025,0.613331,0.38226,0.133942,0.399688,0.74741,0.896886,0.273327,0.0916359,0.0285758,0.453591,0.0850386,0.892346,0.193804,0.565328,0.448703,0.105131,0.180085,1.24473,0.51446,0.418456,0.203128,0.294713,0.634431,0.239128,0.523916,0.0707419,0.204367,0.326867,0.644951,0.534336,0.247239,0.166621,0.0757641,0.451112,0.465864,0.428923,0.305538,0.366398,0.132001,0.42597,0.85762,0.172475,0.909778,0.239273,0.144946,0.268299,0.584509,0.907487,0.316778,0.768874,0.164033,1.4714,0.284644,0.494514,0.386747,0.529441,0.564968,0.572368,0.307225,0.347468,0.360662,0.272401,0.171576,0.513774,0.397678,0.0937398,0.000603662,0.656538,0.207637,1.06309,0.64713,0.40175,0.34595,0.685263,0.0529479,0.254122,0.331969,0.348163,0.204536,0.359394,0.354785,0.335693,0.436484,0.247661,0.246912,0.0872264,0.290513,0.0973104,0.356705,0.0375205,0.449672,0.437975,0.151582,0.106977,1.57323,0.388768,0.363399,0.0771455,0.260696,1.60812,0.499163,1.19423,0.461462,1.08366,0.702969,0.310043,0.412705,0.340627,1.42573,1.41356,1.08232,0.917571,0.556974,0.880148,0.673182,0.0173461,0.48196,0.617124,0.628575,1.42304,1.03234,0.588705,0.93157,0.910596,0.242322,0.295293,0.595289,1.38398,0.839884,0.0836696,0.670986,0.32218,0.452434,0.129483,0.447481,0.522448,0.167242,0.255755,1.69914,0.0614775,0.637161,0.396979,0.310383,0.201723,0.239991,0.141571,0.178463,0.12017,0.189934
}}
}}

Revision as of 18:04, 26 November 2012


Phase1 CAGE Peaks

 Short description
Mm9::chr11:102214546..102214569,-p@chr11:102214546..102214569
-
Mm9::chr11:102214630..102214658,-p@chr11:102214630..102214658
-
Mm9::chr11:102218475..102218486,-p@chr11:102218475..102218486
-
Mm9::chr11:95238906..95238922,+p@chr11:95238906..95238922
+
Mm9::chr13:47201101..47201115,-p10@Dek
Mm9::chr14:69860634..69860655,-p@chr14:69860634..69860655
-
Mm9::chr14:69861633..69861672,-p@chr14:69861633..69861672
-
Mm9::chr14:69862027..69862070,-p@chr14:69862027..69862070
-
Mm9::chr14:69867395..69867407,-p@chr14:69867395..69867407
-
Mm9::chr15:103079752..103079774,-p@chr15:103079752..103079774
-
Mm9::chr16:32630179..32630192,+p@chr16:32630179..32630192
+
Mm9::chr16:32630197..32630206,+p@chr16:32630197..32630206
+
Mm9::chr17:47735613..47735657,+p@chr17:47735613..47735657
+
Mm9::chr18:64616946..64616963,-p@chr18:64616946..64616963
-
Mm9::chr1:134254052..134254079,-p@chr1:134254052..134254079
-
Mm9::chr1:134254118..134254132,-p@chr1:134254118..134254132
-
Mm9::chr1:134254201..134254237,-p@chr1:134254201..134254237
-
Mm9::chr1:134257248..134257260,-p@chr1:134257248..134257260
-
Mm9::chr2:131014815..131014832,+p@chr2:131014815..131014832
+
Mm9::chr2:131019004..131019012,+p@chr2:131019004..131019012
+
Mm9::chr2:163453686..163453707,-p@chr2:163453686..163453707
-
Mm9::chr3:100276521..100276540,-p@chr3:100276521..100276540
-
Mm9::chr3:121948828..121948839,+p7@Gclm
Mm9::chr3:36466826..36466850,-p@chr3:36466826..36466850
-
Mm9::chr3:84284193..84284220,+p@chr3:84284193..84284220
+
Mm9::chr4:118859919..118859942,-p@chr4:118859919..118859942
-
Mm9::chr4:135748823..135748835,+p@chr4:135748823..135748835
+
Mm9::chr4:46409733..46409745,-p@chr4:46409733..46409745
-
Mm9::chr7:134362245..134362250,-p9@Sept1
Mm9::chr8:108298224..108298257,-p@chr8:108298224..108298257
-
Mm9::chrX:146988548..146988561,+p3@Alas2
Mm9::chrX:147001144..147001172,+p2@Alas2


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0005381iron ion transmembrane transporter activity0.000456819144618196
GO:0051301cell division0.000733726995788518
GO:0016538cyclin-dependent protein kinase regulator activity0.0026114002127088
GO:0006873cellular ion homeostasis0.0026114002127088
GO:0055082cellular chemical homeostasis0.0026114002127088
GO:0006879cellular iron ion homeostasis0.0026114002127088
GO:0055072iron ion homeostasis0.0026114002127088
GO:0046915transition metal ion transmembrane transporter activity0.0026114002127088
GO:0050801ion homeostasis0.00265023647613552
GO:0015082di-, tri-valent inorganic cation transmembrane transporter activity0.00374559201860592
GO:0048878chemical homeostasis0.00404491782573569
GO:0019725cellular homeostasis0.00404491782573569
GO:0007049cell cycle0.00798705738009567
GO:0019887protein kinase regulator activity0.0081313237622078
GO:0048250mitochondrial iron ion transport0.0081313237622078
GO:0035229positive regulation of glutamate-cysteine ligase activity0.0081313237622078
GO:0035226glutamate-cysteine ligase catalytic subunit binding0.0081313237622078
GO:0035227regulation of glutamate-cysteine ligase activity0.0081313237622078
GO:0051351positive regulation of ligase activity0.0081313237622078
GO:0042592homeostatic process0.00854684043983682
GO:0019207kinase regulator activity0.00959426906029585
GO:0051882mitochondrial depolarization0.0106522111007838
GO:0016749N-succinyltransferase activity0.0106522111007838
GO:0004357glutamate-cysteine ligase activity0.0106522111007838
GO:0004998transferrin receptor activity0.0106522111007838
GO:0051340regulation of ligase activity0.0106522111007838
GO:0051900regulation of mitochondrial depolarization0.0106522111007838
GO:0017109glutamate-cysteine ligase complex0.0106522111007838
GO:00038705-aminolevulinate synthase activity0.0106522111007838
GO:0030005cellular di-, tri-valent inorganic cation homeostasis0.010902254789028
GO:0051188cofactor biosynthetic process0.010902254789028
GO:0055066di-, tri-valent inorganic cation homeostasis0.0110021371492729
GO:0030003cellular cation homeostasis0.0120011801332138
GO:0055080cation homeostasis0.0123224510919724
GO:0007144female meiosis I0.012520457965269
GO:0016748succinyltransferase activity0.012520457965269
GO:0051881regulation of mitochondrial membrane potential0.012520457965269
GO:0042541hemoglobin biosynthetic process0.0156168431581143
GO:0001940male pronucleus0.0156168431581143
GO:0022890inorganic cation transmembrane transporter activity0.0156168431581143
GO:0043085positive regulation of catalytic activity0.0159305284196433
GO:0001556oocyte maturation0.0171492062413345
GO:0020027hemoglobin metabolic process0.0171492062413345
GO:0001939female pronucleus0.0171492062413345
GO:0006534cysteine metabolic process0.0171492062413345
GO:0022402cell cycle process0.0172638545631914
GO:0006750glutathione biosynthetic process0.0196984864028533
GO:0007067mitosis0.0210190108072703
GO:0000087M phase of mitotic cell cycle0.0210190108072703
GO:0065008regulation of biological quality0.0210850417664668
GO:0048599oocyte development0.0232427130231152
GO:0009994oocyte differentiation0.0232427130231152
GO:0007143female meiosis0.0232427130231152
GO:0051186cofactor metabolic process0.0232427130231152
GO:0006783heme biosynthetic process0.0308229493562097
GO:0000278mitotic cell cycle0.0318412966535553
GO:0000279M phase0.0332048536694561
GO:0006779porphyrin biosynthetic process0.0339407523590761
GO:0033014tetrapyrrole biosynthetic process0.0339407523590761
GO:0045120pronucleus0.0359335298015824
GO:0065007biological regulation0.0388170245174001
GO:0000096sulfur amino acid metabolic process0.0390459646284324
GO:0042168heme metabolic process0.0390459646284324
GO:0050790regulation of catalytic activity0.0390459646284324
GO:0022403cell cycle phase0.0390459646284324
GO:0009069serine family amino acid metabolic process0.0390459646284324
GO:0051899membrane depolarization0.0390459646284324
GO:0033013tetrapyrrole metabolic process0.0400006848200994
GO:0006778porphyrin metabolic process0.0400006848200994
GO:0046873metal ion transmembrane transporter activity0.0400006848200994
GO:0006749glutathione metabolic process0.0411607496894537
GO:0048477oogenesis0.0448395069175333
GO:0065009regulation of a molecular function0.0456768811291409
GO:0006839mitochondrial transport0.0456938762583261



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}

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