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Coexpression cluster:C197

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Full id: C197_tongue_esophagus_tonsil_salivary_cervix_nasal_Gingival



Phase1 CAGE Peaks

Hg19::chr11:93754560..93754567,+p@chr11:93754560..93754567
+
Hg19::chr12:101962128..101962133,+p19@MYBPC1
Hg19::chr12:52862701..52862727,-p@chr12:52862701..52862727
-
Hg19::chr12:52867581..52867598,-p1@KRT6C
Hg19::chr12:53189894..53189905,-p1@KRT3
Hg19::chr12:57328187..57328195,-p1@SDR9C7
Hg19::chr13:103532389..103532398,+p3@METTL21CP1
Hg19::chr13:103532465..103532483,+p1@METTL21CP1
Hg19::chr13:103532691..103532727,+p@chr13:103532691..103532727
+
Hg19::chr13:103555653..103555668,+p@chr13:103555653..103555668
+
Hg19::chr13:103555674..103555696,+p@chr13:103555674..103555696
+
Hg19::chr13:103555720..103555725,+p@chr13:103555720..103555725
+
Hg19::chr16:28890820..28890826,+p@chr16:28890820..28890826
+
Hg19::chr17:10453082..10453093,-p7@MYH2
Hg19::chr17:10515218..10515226,+p@chr17:10515218..10515226
+
Hg19::chr17:39646159..39646164,-p1@KRT36
Hg19::chr17:39766130..39766139,-p@chr17:39766130..39766139
-
Hg19::chr17:7991002..7991009,-p8@ALOX12B
Hg19::chr17:7991027..7991040,-p1@ALOX12B
Hg19::chr17:7991064..7991073,-p4@ALOX12B
Hg19::chr17:7991075..7991086,-p2@ALOX12B
Hg19::chr18:28682160..28682171,-p11@DSC2
Hg19::chr18:52258473..52258477,+p1@C18orf26
Hg19::chr19:36018336..36018343,-p@chr19:36018336..36018343
-
Hg19::chr19:36591495..36591511,+p@chr19:36591495..36591511
+
Hg19::chr19:42891296..42891305,-p@chr19:42891296..42891305
-
Hg19::chr19:51563807..51563817,-p@chr19:51563807..51563817
-
Hg19::chr1:109427881..109427897,+p5@GPSM2
Hg19::chr1:152130293..152130302,-p@chr1:152130293..152130302
-
Hg19::chr1:152131703..152131706,-p1@RPTN
Hg19::chr1:152957997..152958025,+p4@SPRR1A
Hg19::chr1:153004800..153004809,+p6@SPRR1B
Hg19::chr1:153004839..153004866,+p2@SPRR1B
Hg19::chr1:153004879..153004890,+p4@SPRR1B
Hg19::chr1:153005112..153005146,+p@chr1:153005112..153005146
+
Hg19::chr1:153005159..153005205,+p@chr1:153005159..153005205
+
Hg19::chr1:153013588..153013605,-p1@SPRR2D
Hg19::chr1:153029029..153029042,-p@chr1:153029029..153029042
-
Hg19::chr1:153029980..153029995,-p1@SPRR2A
Hg19::chr1:153044083..153044088,-p1@SPRR2B
Hg19::chr1:153066998..153067008,-p1@SPRR2E
Hg19::chr1:153085984..153085999,-p1@SPRR2F
p2@SPRR2A
Hg19::chr1:153113940..153113972,-p1@SPRR2C
p2@SPRR2D
p3@SPRR2A
Hg19::chr1:153113974..153113991,-p3@SPRR2C
p4@SPRR2D
p5@SPRR2A
Hg19::chr1:153114001..153114013,-p2@SPRR2C
p3@SPRR2D
p4@SPRR2A
Hg19::chr1:153114023..153114029,-p4@SPRR2C
p5@SPRR2D
p6@SPRR2A
Hg19::chr1:153123359..153123372,-p1@SPRR2G
Hg19::chr1:153388993..153389000,+p1@S100A7A
Hg19::chr1:153430341..153430348,-p6@S100A7
Hg19::chr1:153430422..153430443,-p3@S100A7
Hg19::chr1:153431372..153431378,-p4@S100A7
Hg19::chr1:153433120..153433129,-p1@S100A7
Hg19::chr1:159832438..159832449,-p1@VSIG8
Hg19::chr1:1846607..1846616,+p6@CALML6
Hg19::chr1:1846804..1846823,+p3@CALML6
Hg19::chr20:2290823..2290833,+p@chr20:2290823..2290833
+
Hg19::chr20:2312685..2312717,+p@chr20:2312685..2312717
+
Hg19::chr20:2321399..2321407,+p@chr20:2321399..2321407
+
Hg19::chr20:43803535..43803553,+p1@PI3
Hg19::chr20:43804494..43804505,+p@chr20:43804494..43804505
+
Hg19::chr20:43804621..43804628,+p@chr20:43804621..43804628
+
Hg19::chr20:43804675..43804691,+p@chr20:43804675..43804691
+
Hg19::chr21:31768348..31768356,+p1@KRTAP13-1
Hg19::chr21:45743612..45743625,+p@chr21:45743612..45743625
+
Hg19::chr2:106128079..106128106,+p@chr2:106128079..106128106
+
Hg19::chr2:113816771..113816777,+p1@IL36RN
Hg19::chr3:133348367..133348368,-p@chr3:133348367..133348368
-
Hg19::chr3:46027166..46027193,-p@chr3:46027166..46027193
-
Hg19::chr3:57286665..57286681,+p@chr3:57286665..57286681
+
Hg19::chr3:57326704..57326721,-p1@ASB14
Hg19::chr4:68749705..68749725,-p1@TMPRSS11D
Hg19::chr4:68749745..68749756,-p2@TMPRSS11D
Hg19::chr5:147715119..147715124,+p1@SPINK9
Hg19::chr5:150040771..150040781,+p7@MYOZ3
Hg19::chr6:2744269..2744281,-p@chr6:2744269..2744281
-
Hg19::chr6:2744361..2744382,-p@chr6:2744361..2744382
-
Hg19::chr6:2744431..2744440,-p@chr6:2744431..2744440
-
Hg19::chr6:2751146..2751162,-p1@MYLK4
Hg19::chr7:141066909..141066949,+p@chr7:141066909..141066949
+
Hg19::chr7:46064019..46064047,-p@chr7:46064019..46064047
-
Hg19::chr7:80412875..80412912,-p@chr7:80412875..80412912
-
Hg19::chr8:143866581..143866589,-p@chr8:143866581..143866589
-
Hg19::chr8:143866652..143866665,-p@chr8:143866652..143866665
-
Hg19::chr9:136184568..136184572,+p1@LCN1P2


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0030216keratinocyte differentiation1.41377271188228e-22
GO:0001533cornified envelope2.09843797592739e-21
GO:0008544epidermis development3.54818497190057e-18
GO:0007398ectoderm development6.47311958840782e-18
GO:0007566embryo implantation9.0240676857688e-17
GO:0031424keratinization1.15717915921942e-16
GO:0009913epidermal cell differentiation9.09423997553288e-16
GO:0048730epidermis morphogenesis2.14163868075365e-15
GO:0009888tissue development9.8258948593668e-15
GO:0042698menstrual cycle9.8258948593668e-15
GO:0048729tissue morphogenesis1.51753803813706e-14
GO:0005856cytoskeleton7.05958323542508e-13
GO:0048609reproductive process in a multicellular organism7.05958323542508e-13
GO:0032504multicellular organism reproduction7.05958323542508e-13
GO:0007565female pregnancy5.19500409919953e-12
GO:0022414reproductive process1.30575350682352e-09
GO:0051704multi-organism process2.46426429272213e-09
GO:0048513organ development8.42293050941528e-09
GO:0043232intracellular non-membrane-bound organelle1.28987918594192e-08
GO:0043228non-membrane-bound organelle1.28987918594192e-08
GO:0009653anatomical structure morphogenesis5.70036548952603e-08
GO:0048856anatomical structure development2.00814308172839e-07
GO:0048731system development2.28875902185992e-07
GO:0048869cellular developmental process7.19033913179365e-07
GO:0030154cell differentiation7.19033913179365e-07
GO:0032501multicellular organismal process3.43078017666563e-06
GO:0007275multicellular organismal development7.34854023939061e-06
GO:0005882intermediate filament9.40971067965266e-06
GO:0045111intermediate filament cytoskeleton9.40971067965266e-06
GO:0032502developmental process3.74286315267922e-05
GO:0044430cytoskeletal part4.87757962062124e-05
GO:0030017sarcomere5.39273216063763e-05
GO:0030016myofibril7.06316225131419e-05
GO:0044449contractile fiber part9.97559417589415e-05
GO:0043292contractile fiber0.000116884456891877
GO:0005737cytoplasm0.000116884456891877
GO:0032982myosin filament0.00041900365286357
GO:0005863striated muscle thick filament0.00041900365286357
GO:0005859muscle myosin complex0.00101597587724844
GO:0016460myosin II complex0.00104641705511306
GO:0018149peptide cross-linking0.00104641705511306
GO:0006941striated muscle contraction0.00208158898038636
GO:0044424intracellular part0.00283298113520072
GO:0050829defense response to Gram-negative bacterium0.00746985107196519
GO:0004052arachidonate 12-lipoxygenase activity0.00746985107196519
GO:0043229intracellular organelle0.00845113269078566
GO:0043226organelle0.00845113269078566
GO:0030674protein binding, bridging0.0108954268859156
GO:0016459myosin complex0.0146609841768646
GO:0007620copulation0.0167871400047718
GO:0005622intracellular0.0239417025024281
GO:0005509calcium ion binding0.0244490687094494
GO:0003012muscle system process0.0304615149269455
GO:0006936muscle contraction0.0304615149269455
GO:0030280structural constituent of epidermis0.0304615149269455
GO:0004867serine-type endopeptidase inhibitor activity0.0307654972726924
GO:0007618mating0.0346355881358288
GO:0016165lipoxygenase activity0.0346355881358288
GO:0051238sequestering of metal ion0.0368712827874512
GO:0045104intermediate filament cytoskeleton organization and biogenesis0.0383904072748272
GO:0030018Z disc0.0383904072748272
GO:0045103intermediate filament-based process0.0398109792250047
GO:0000146microfilament motor activity0.0398109792250047
GO:0031674I band0.0443788883667347



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Cell Type
Ontology termp-valuen
endo-epithelial cell1.64e-1243
epithelial cell6.87e-08254
endodermal cell3.59e-0759
Uber Anatomy
Ontology termp-valuen
adult organism6.11e-10115
endoderm-derived structure1.10e-09169
endoderm1.10e-09169
presumptive endoderm1.10e-09169
respiratory system4.58e-0972
embryo1.13e-07612
anatomical system2.23e-07625
embryonic structure2.63e-07605
developing anatomical structure2.63e-07605
anatomical group3.54e-07626
germ layer5.08e-07604
embryonic tissue5.08e-07604
presumptive structure5.08e-07604
epiblast (generic)5.08e-07604
multi-cellular organism6.93e-07659


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

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