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Coexpression cluster:C3785

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Full id: C3785_Osteoblast_Adipocyte_Mesenchymal_Melanocyte_embryonic_melanoma_Smooth



Phase1 CAGE Peaks

Hg19::chr19:3978083..3978133,-p@chr19:3978083..3978133
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Hg19::chr19:3983156..3983231,-p@chr19:3983156..3983231
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Hg19::chr22:24236927..24236999,+p3@MIF


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
trunk2.47e-13216
multilaminar epithelium1.16e-1282
dermomyotome9.01e-1270
splanchnic layer of lateral plate mesoderm2.15e-1184
unilaminar epithelium5.23e-11138
trunk mesenchyme1.04e-10143
skeletal muscle tissue1.12e-1061
striated muscle tissue1.12e-1061
myotome1.12e-1061
muscle tissue1.71e-1063
musculature1.71e-1063
musculature of body1.71e-1063
epithelial tube1.78e-10118
artery2.09e-1042
arterial blood vessel2.09e-1042
arterial system2.09e-1042
blood vessel4.62e-1060
epithelial tube open at both ends4.62e-1060
blood vasculature4.62e-1060
vascular cord4.62e-1060
mesenchyme4.75e-10238
entire embryonic mesenchyme4.75e-10238
vessel5.75e-1069
somite6.01e-0983
paraxial mesoderm6.01e-0983
presomitic mesoderm6.01e-0983
presumptive segmental plate6.01e-0983
trunk paraxial mesoderm6.01e-0983
presumptive paraxial mesoderm6.01e-0983
vasculature8.95e-0979
vascular system8.95e-0979
systemic artery7.04e-0833
systemic arterial system7.04e-0833
mesoderm3.05e-07448
mesoderm-derived structure3.05e-07448
presumptive mesoderm3.05e-07448


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.