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Coexpression cluster:C289

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Full id: C289_chorionic_skeletal_heart_Mast_amniotic_granulosa_left



Phase1 CAGE Peaks

Hg19::chr10:100150986..100150988,+p@chr10:100150986..100150988
+
Hg19::chr10:134275596..134275597,+p@chr10:134275596..134275597
+
Hg19::chr11:2150786..2150798,+p3@BC127839
Hg19::chr11:57154835..57154847,+p2@CU675194
Hg19::chr11:57154881..57154893,+p1@CU675194
Hg19::chr11:57154962..57154970,+p3@CU675194
Hg19::chr11:57156054..57156064,+p@chr11:57156054..57156064
+
Hg19::chr11:57156676..57156686,+p@chr11:57156676..57156686
+
Hg19::chr11:57156718..57156726,+p@chr11:57156718..57156726
+
Hg19::chr11:63488452..63488456,+p@chr11:63488452..63488456
+
Hg19::chr11:71710984..71711008,+p9@IL18BP
Hg19::chr11:71711013..71711028,+p6@IL18BP
Hg19::chr12:52301235..52301246,+p13@ACVRL1
Hg19::chr12:95267095..95267097,+p@chr12:95267095..95267097
+
Hg19::chr14:105359977..105359978,+p4@KIAA0284
Hg19::chr14:34516082..34516087,-p@chr14:34516082..34516087
-
Hg19::chr14:65105965..65105968,-p@chr14:65105965..65105968
-
Hg19::chr16:66959429..66959444,-p1@RRAD
Hg19::chr17:15686350..15686359,+p4@IL6STP1
Hg19::chr17:18164614..18164617,-p@chr17:18164614..18164617
-
Hg19::chr18:47766907..47766915,+p@chr18:47766907..47766915
+
Hg19::chr19:4210133..4210148,-p@chr19:4210133..4210148
-
Hg19::chr19:9783972..9783976,+p@chr19:9783972..9783976
+
Hg19::chr1:103299100..103299144,+p@chr1:103299100..103299144
+
Hg19::chr1:43988983..43989012,+p@chr1:43988983..43989012
+
Hg19::chr1:799209..799212,+p@chr1:799209..799212
+
Hg19::chr3:15493229..15493233,-p@chr3:15493229..15493233
-
Hg19::chr3:194215056..194215071,-p@chr3:194215056..194215071
-
Hg19::chr3:45596863..45596884,+p13@LIMD1
Hg19::chr3:4723000..4723006,+p@chr3:4723000..4723006
+
Hg19::chr3:97910197..97910206,+p@chr3:97910197..97910206
+
Hg19::chr5:115265770..115265773,-p@chr5:115265770..115265773
-
Hg19::chr5:127607810..127607838,-p@chr5:127607810..127607838
-
Hg19::chr5:176152899..176152904,+p@chr5:176152899..176152904
+
Hg19::chr5:2749492..2749495,-p@chr5:2749492..2749495
-
Hg19::chr6:161459302..161459304,+p@chr6:161459302..161459304
+
Hg19::chr6:36293751..36293753,-p@chr6:36293751..36293753
-
Hg19::chr6:4488206..4488213,+p@chr6:4488206..4488213
+
Hg19::chr6:80023101..80023112,-p3@uc003piw.1
Hg19::chr7:138848445..138848454,+p@chr7:138848445..138848454
+
Hg19::chr7:45932645..45932656,+p2@AF042356
Hg19::chr8:102466479..102466487,+p@chr8:102466479..102466487
+
Hg19::chr8:62490697..62490708,+p1@uc003xuk.2
Hg19::chr9:4299962..4299963,+p@chr9:4299962..4299963
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0019838growth factor binding0.0135994348286824
GO:0019955cytokine binding0.0135994348286824
GO:0042007interleukin-18 binding0.0135994348286824
GO:0005057receptor signaling protein activity0.0174818995682708
GO:0035313wound healing, spreading of epidermal cells0.0174818995682708
GO:0050431transforming growth factor beta binding0.0174818995682708
GO:0051895negative regulation of focal adhesion formation0.0174818995682708
GO:0016361activin receptor activity, type I0.0176731998586883
GO:0051893regulation of focal adhesion formation0.0176731998586883
GO:0005025transforming growth factor beta receptor activity, type I0.0176731998586883
GO:0017002activin receptor activity0.0176731998586883
GO:0006349genetic imprinting0.0176731998586883
GO:0048185activin binding0.0176731998586883
GO:0007165signal transduction0.0176731998586883
GO:0001953negative regulation of cell-matrix adhesion0.0176731998586883
GO:0007167enzyme linked receptor protein signaling pathway0.0176731998586883
GO:0018445prothoracicotrophic hormone activity0.0176731998586883
GO:0007154cell communication0.0176731998586883
GO:0030547receptor inhibitor activity0.0176731998586883
GO:0048019receptor antagonist activity0.0176731998586883
GO:0005515protein binding0.0176731998586883
GO:0022408negative regulation of cell-cell adhesion0.018269524327721
GO:0005159insulin-like growth factor receptor binding0.018269524327721
GO:0030545receptor regulator activity0.018269524327721
GO:0042088T-helper 1 type immune response0.018269524327721
GO:0032502developmental process0.018269524327721
GO:0022407regulation of cell-cell adhesion0.018269524327721
GO:0048041focal adhesion formation0.018269524327721
GO:0001952regulation of cell-matrix adhesion0.018269524327721
GO:0046332SMAD binding0.021730292128721
GO:0004675transmembrane receptor protein serine/threonine kinase activity0.0229146203514971
GO:0005024transforming growth factor beta receptor activity0.0229146203514971
GO:0030336negative regulation of cell migration0.0234526246261097
GO:0051271negative regulation of cell motility0.0275452882691319
GO:0040013negative regulation of locomotion0.0279192182649181
GO:0007162negative regulation of cell adhesion0.0294004658922312
GO:0048856anatomical structure development0.0321170087531403
GO:0008286insulin receptor signaling pathway0.0342625499906871
GO:0005184neuropeptide hormone activity0.034424234422504
GO:0005520insulin-like growth factor binding0.0386319699557641
GO:0019965interleukin binding0.0396663923494634
GO:0007275multicellular organismal development0.041527046048951
GO:0008283cell proliferation0.0431655393324574
GO:0007179transforming growth factor beta receptor signaling pathway0.0461615641177144
GO:0008217regulation of blood pressure0.049627418817607



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Cell Type
Ontology termp-valuen
chorionic membrane mesenchymal stem cell9.61e-853
extraembryonic cell2.45e-2419
amnion mesenchymal stem cell5.08e-075
Uber Anatomy
Ontology termp-valuen
acellular anatomical structure9.61e-853
egg chorion9.61e-853
chorion1.32e-647
extraembryonic membrane1.37e-5014
membranous layer1.37e-5014
extraembryonic structure9.15e-3024
organ component layer4.31e-1166
placenta2.11e-084
allantois2.11e-084


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

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