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MCL coexpression mm9:2571

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Phase1 CAGE Peaks

 Short description
Mm9::chr10:62801771..62801790,-p1@Sirt1
Mm9::chr11:51076447..51076456,+p3@Clk4
Mm9::chr5:24348806..24348819,+p@chr5:24348806..24348819
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0017136NAD-dependent histone deacetylase activity0.0164356544129732
GO:0016575histone deacetylation0.0205366887714151
GO:0006476protein amino acid deacetylation0.0205366887714151
GO:0005677chromatin silencing complex0.0205366887714151
GO:0001542ovulation from ovarian follicle0.0205366887714151
GO:0030728ovulation0.0205366887714151
GO:0004407histone deacetylase activity0.0205366887714151
GO:0033558protein deacetylase activity0.0205366887714151
GO:0006342chromatin silencing0.0205366887714151
GO:0031507heterochromatin formation0.0205366887714151
GO:0019213deacetylase activity0.0205366887714151
GO:0045814negative regulation of gene expression, epigenetic0.0205366887714151
GO:0016585chromatin remodeling complex0.0243007796075995
GO:0016458gene silencing0.0243007796075995
GO:0022601menstrual cycle phase0.0243007796075995
GO:0022602menstrual cycle process0.0243007796075995
GO:0046777protein amino acid autophosphorylation0.0243007796075995
GO:0016570histone modification0.0243007796075995
GO:0008585female gonad development0.0243007796075995
GO:0016540protein autoprocessing0.0243007796075995
GO:0007292female gamete generation0.0243007796075995
GO:0046545development of primary female sexual characteristics0.0243007796075995
GO:0046660female sex differentiation0.0243007796075995
GO:0006338chromatin remodeling0.0243007796075995
GO:0016569covalent chromatin modification0.0243007796075995
GO:0042698menstrual cycle0.0252114286319411
GO:0043687post-translational protein modification0.0252114286319411
GO:0040029regulation of gene expression, epigenetic0.0252114286319411
GO:0016811hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides0.0271688160209374
GO:0008406gonad development0.0271936986871097
GO:0048608reproductive structure development0.0271936986871097
GO:0018212peptidyl-tyrosine modification0.0271936986871097
GO:0018108peptidyl-tyrosine phosphorylation0.0271936986871097
GO:0006464protein modification process0.0271936986871097
GO:0045137development of primary sexual characteristics0.0271936986871097
GO:0043412biopolymer modification0.0277475735057699
GO:0016485protein processing0.029265450018203
GO:0048609reproductive process in a multicellular organism0.0298639425076289
GO:0032504multicellular organism reproduction0.0298639425076289
GO:0007548sex differentiation0.0299359074312822
GO:0003006reproductive developmental process0.0343945123512573
GO:0016810hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds0.0351333917681283
GO:0018193peptidyl-amino acid modification0.035394693253886
GO:0007519skeletal muscle development0.035394693253886
GO:0031497chromatin assembly0.0386037370684783
GO:0014706striated muscle development0.0434457251676283
GO:0006333chromatin assembly or disassembly0.0456468744106684



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Cell Type
Ontology termp-valuen
intestinal epithelial cell4.33e-079
epithelial cell of alimentary canal4.33e-079

Uber Anatomy
Ontology termp-valuen
simple columnar epithelium8.06e-0811
epithelium of mucosa4.33e-079
gastrointestinal system epithelium4.33e-079
intestinal epithelium4.33e-079


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.11.35193
MA0004.11.8803
MA0006.11.46714
MA0007.11.84502
MA0009.11.27673
MA0014.11.93445
MA0017.10.635031
MA0019.11.08369
MA0024.11.23079
MA0025.11.51835
MA0027.12.9431
MA0028.10.61552
MA0029.11.20789
MA0030.11.21482
MA0031.11.17722
MA0038.12.2112
MA0040.11.28983
MA0041.10.714279
MA0042.10.69885
MA0043.11.3775
MA0046.11.31428
MA0048.10.353763
MA0050.10.845669
MA0051.10.973068
MA0052.11.29825
MA0055.10.190475
MA0056.10
MA0057.10.337566
MA0058.12.77886
MA0059.11.68104
MA0060.11.25521
MA0061.10.5406
MA0063.10
MA0066.10.951196
MA0067.11.63197
MA0068.10.343188
MA0069.11.29861
MA0070.11.28847
MA0071.10.844726
MA0072.11.2796
MA0073.10.121346
MA0074.10.911576
MA0076.10.657929
MA0077.11.2569
MA0078.11.0091
MA0081.10.732313
MA0083.11.37668
MA0084.11.96428
MA0087.11.33189
MA0088.10.27999
MA0089.10
MA0090.10.762482
MA0091.10.816659
MA0092.10.762845
MA0093.12.57012
MA0095.10
MA0098.10
MA0100.12.07939
MA0101.10.71579
MA0103.10.647985
MA0105.10.405648
MA0106.11.01755
MA0107.10.640607
MA0108.21.10817
MA0109.10
MA0111.10.778753
MA0113.10.986839
MA0114.10.537669
MA0115.11.38041
MA0116.11.46662
MA0117.11.34691
MA0119.10.716476
MA0122.11.36752
MA0124.11.57762
MA0125.11.5017
MA0130.10
MA0131.11.07881
MA0132.10
MA0133.10
MA0135.11.4152
MA0136.10.933582
MA0139.10.462282
MA0140.10.898603
MA0141.10.671467
MA0142.11.16183
MA0143.11.00467
MA0144.10.541532
MA0145.10.794492
MA0146.10.46063
MA0147.12.34772
MA0148.10.820161
MA0149.10.722227
MA0062.21.06145
MA0035.20.903829
MA0039.21.55941
MA0138.21.07027
MA0002.20.466067
MA0137.20.668025
MA0104.22.10982
MA0047.20.962424
MA0112.20.29236
MA0065.20.79573
MA0150.10.784464
MA0151.10
MA0152.10.962542
MA0153.11.43238
MA0154.10.35067
MA0155.10.312898
MA0156.10.656895
MA0157.11.12772
MA0158.10
MA0159.11.39671
MA0160.10.823568
MA0161.10
MA0162.12.92952
MA0163.10.157796
MA0164.10.933981
MA0080.20.64167
MA0018.20.944669
MA0099.21.06348
MA0079.20.288542
MA0102.22.01714
MA0258.10.520639
MA0259.10.543506
MA0442.10
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