CL:0000214

Name:	synovial cell
Namespace:	FANTOM
Definition:	"A meso-epithelial cell that lies between the cartilaginous fibers in the synovial membrane of a joint and produces hyaluronic acid." [GOC:tfm, ISBN:0721662544, PMID:17942474]
Xrefs:	Expandlinks: BTO:0003652 FMA:66786
Synonyms:	"hyaluronic acid secreting cell" EXACT [] "synoviocyte" EXACT []

Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data

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Parents

is_a:	CL:0000153(GAG secreting cell),CL:0000213(lining cell),CL:0002078(meso-epithelial cell)
develops_from:	CL:0000134(mesenchymal cell)
part_of:	UBERON:0002018(synovial membrane of synovial joint)

Children

is a:	FF:10441-106E9 (synovial sarcoma cell line:HS-SY-II)
derives from:	FF:0000187 (human synovial cell sample)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.

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Human (Homo sapiens)

• 10441-106E9 (synovial sarcoma cell line:HS-SY-II)
• 11291-117A4 (Synoviocyte, donor1)
• 11368-117I9 (Synoviocyte, donor2)
• 11440-118H9 (Synoviocyte, donor3)

Mouse (Mus musculus)

• 10441-106E9 (synovial sarcoma cell line:HS-SY-II)
• 11291-117A4 (Synoviocyte, donor1)
• 11368-117I9 (Synoviocyte, donor2)
• 11440-118H9 (Synoviocyte, donor3)

Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000214 (synovial cell), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

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P-value	FFCP	Short description

P-value	FFCP	Short description
6.24e-88	FFCP PHASE2:Hg19::chr7:80546293..80546302,-	p31@SEMA3C
6.24e-88	FFCP PHASE1:Hg19::chr7:80546293..80546302,-	p31@SEMA3C
1.71e-66	FFCP PHASE2:Hg19::chr18:22150956..22150983,+	p@chr18:22150956..22150983, +
1.71e-66	FFCP PHASE1:Hg19::chr18:22150956..22150983,+	p@chr18:22150956..22150983, +
2.39e-66	FFCP PHASE1:Hg19::chr8:37411632..37411639,-	p1@ENST00000517363
2.39e-66	FFCP PHASE2:Hg19::chr1:172134667..172134711,+	p@chr1:172134667..172134711, +
2.39e-66	FFCP PHASE1:Hg19::chr1:172134667..172134711,+	p@chr1:172134667..172134711, +
2.39e-66	FFCP PHASE1:Hg19::chr12:130786785..130786827,-	p@chr12:130786785..130786827, -
2.39e-66	FFCP PHASE2:Hg19::chr2:181751144..181751146,+	p@chr2:181751144..181751146, +
2.39e-66	FFCP PHASE1:Hg19::chr1:172134736..172134739,+	p@chr1:172134736..172134739, +
2.39e-66	FFCP PHASE1:Hg19::chr2:181751144..181751146,+	p@chr2:181751144..181751146, +
2.39e-66	FFCP PHASE2:Hg19::chr12:130786785..130786827,-	p@chr12:130786785..130786827, -
2.39e-66	FFCP PHASE2:Hg19::chr1:172134736..172134739,+	p@chr1:172134736..172134739, +
2.39e-66	FFCP PHASE2:Hg19::chr15:68117826..68117829,+	p9@SKOR1
2.39e-66	FFCP PHASE1:Hg19::chr15:68117826..68117829,+	p9@SKOR1
2.39e-66	FFCP PHASE1:Hg19::chr1:172134755..172134764,+	p@chr1:172134755..172134764, +
2.39e-66	FFCP PHASE2:Hg19::chr1:172134755..172134764,+	p@chr1:172134755..172134764, +
2.39e-66	FFCP PHASE2:Hg19::chr8:37411632..37411639,-	p1@ENST00000517363
1.68e-53	FFCP PHASE2:Hg19::chr8:25337208..25337219,+	p5@CDCA2
1.68e-53	FFCP PHASE1:Hg19::chr8:25337208..25337219,+	p5@CDCA2
2.19e-53	FFCP PHASE2:Hg19::chr2:242009429..242009432,+	p@chr2:242009429..242009432, +
2.19e-53	FFCP PHASE1:Hg19::chr2:242009429..242009432,+	p@chr2:242009429..242009432, +
2.87e-53	FFCP PHASE1:Hg19::chr12:131476821..131476831,-	p@chr12:131476821..131476831, -
2.87e-53	FFCP PHASE2:Hg19::chr12:131476821..131476831,-	p@chr12:131476821..131476831, -
1.22e-44	FFCP PHASE2:Hg19::chrY:58884631..58884640,+	p@chrY:58884631..58884640, +
1.22e-44	FFCP PHASE1:Hg19::chrY:58884631..58884640,+	p@chrY:58884631..58884640, +
1.8e-38	FFCP PHASE2:Hg19::chr1:142537706..142537723,-	p@chr1:142537706..142537723, -
1.8e-38	FFCP PHASE1:Hg19::chr1:142537706..142537723,-	p@chr1:142537706..142537723, -
1.85e-36	FFCP PHASE1:Hg19::chr10:131634104..131634108,-	p@chr10:131634104..131634108, -
1.85e-36	FFCP PHASE2:Hg19::chr10:131634104..131634108,-	p@chr10:131634104..131634108, -
3.33e-34	FFCP PHASE2:Hg19::chr17:9066265..9066271,+	p@chr17:9066265..9066271, +
3.33e-34	FFCP PHASE1:Hg19::chr17:9066265..9066271,+	p@chr17:9066265..9066271, +
4.27e-34	FFCP PHASE2:Hg19::chr4:139010162..139010169,+	p1@LOC641364
4.27e-34	FFCP PHASE1:Hg19::chr4:139010162..139010169,+	p1@LOC641364
4.27e-34	FFCP PHASE2:Hg19::chr8:37411648..37411657,-	p1@ENST00000519738
4.27e-34	FFCP PHASE1:Hg19::chr8:37411648..37411657,-	p1@ENST00000519738
4.27e-34	FFCP PHASE2:Hg19::chr15:68118244..68118272,+	p@chr15:68118244..68118272, +
4.27e-34	FFCP PHASE1:Hg19::chr15:68118244..68118272,+	p@chr15:68118244..68118272, +
4.27e-34	FFCP PHASE2:Hg19::chr12:91435143..91435151,-	p@chr12:91435143..91435151, -
4.27e-34	FFCP PHASE1:Hg19::chr12:54379011..54379016,+	p15@HOXC10
4.27e-34	FFCP PHASE1:Hg19::chr12:91435143..91435151,-	p@chr12:91435143..91435151, -
4.27e-34	FFCP PHASE1:Hg19::chr10:135140510..135140524,-	p@chr10:135140510..135140524, -
4.27e-34	FFCP PHASE2:Hg19::chr12:54379011..54379016,+	p15@HOXC10
4.27e-34	FFCP PHASE2:Hg19::chr5:1043105..1043109,+	p@chr5:1043105..1043109, +
4.27e-34	FFCP PHASE2:Hg19::chr15:68124311..68124318,+	p@chr15:68124311..68124318, +
4.27e-34	FFCP PHASE1:Hg19::chr12:130646534..130646542,+	p5@FZD10
4.27e-34	FFCP PHASE2:Hg19::chr10:135140510..135140524,-	p@chr10:135140510..135140524, -
4.27e-34	FFCP PHASE1:Hg19::chr5:1043105..1043109,+	p@chr5:1043105..1043109, +
4.27e-34	FFCP PHASE1:Hg19::chr8:78774585..78774589,-	p@chr8:78774585..78774589, -
4.27e-34	FFCP PHASE1:Hg19::chr15:68124311..68124318,+	p@chr15:68124311..68124318, +
4.27e-34	FFCP PHASE2:Hg19::chr8:78774585..78774589,-	p@chr8:78774585..78774589, -
4.27e-34	FFCP PHASE2:Hg19::chr12:130646534..130646542,+	p5@FZD10
5.51e-34	FFCP PHASE1:Hg19::chr15:89402148..89402159,+	p6@ACAN
5.51e-34	FFCP PHASE2:Hg19::chr15:89402148..89402159,+	p6@ACAN
5.96e-34	FFCP PHASE1:Hg19::chr15:68117844..68117858,+	p3@SKOR1
5.96e-34	FFCP PHASE2:Hg19::chr17:63705566..63705573,-	p@chr17:63705566..63705573, -
5.96e-34	FFCP PHASE1:Hg19::chr17:63705566..63705573,-	p@chr17:63705566..63705573, -
5.96e-34	FFCP PHASE1:Hg19::chr1:172145683..172145699,+	p@chr1:172145683..172145699, +
5.96e-34	FFCP PHASE2:Hg19::chr1:172145683..172145699,+	p@chr1:172145683..172145699, +
5.96e-34	FFCP PHASE1:Hg19::chr13:73102090..73102097,-	p@chr13:73102090..73102097, -
5.96e-34	FFCP PHASE2:Hg19::chr13:73102090..73102097,-	p@chr13:73102090..73102097, -
5.96e-34	FFCP PHASE2:Hg19::chr6:42072877..42072881,-	p11@C6orf132
5.96e-34	FFCP PHASE1:Hg19::chr6:42072877..42072881,-	p11@C6orf132
5.96e-34	FFCP PHASE1:Hg19::chr12:54366780..54366791,+	p12@HOXC11
5.96e-34	FFCP PHASE2:Hg19::chr12:54366780..54366791,+	p12@HOXC11
5.96e-34	FFCP PHASE2:Hg19::chr15:68117844..68117858,+	p3@SKOR1
7.7e-34	FFCP PHASE1:Hg19::chrY:13450855..13450866,+	p@chrY:13450855..13450866, +
7.7e-34	FFCP PHASE2:Hg19::chrY:13450855..13450866,+	p@chrY:13450855..13450866, +
1.46e-31	FFCP PHASE1:Hg19::chr19:18718172..18718197,+	p@chr19:18718172..18718197, +
1.46e-31	FFCP PHASE2:Hg19::chr19:18718172..18718197,+	p@chr19:18718172..18718197, +
1.71e-30	FFCP PHASE2:Hg19::chr21:39821025..39821046,-	p9@ERG
1.71e-30	FFCP PHASE1:Hg19::chr21:39821025..39821046,-	p9@ERG
2.3e-30	FFCP PHASE2:Hg19::chr15:89402048..89402061,+	p8@ACAN
2.3e-30	FFCP PHASE1:Hg19::chr1:186273262..186273282,+	p@chr1:186273262..186273282, +
2.3e-30	FFCP PHASE1:Hg19::chr15:89402048..89402061,+	p8@ACAN
2.3e-30	FFCP PHASE2:Hg19::chr1:186273262..186273282,+	p@chr1:186273262..186273282, +
7.54e-30	FFCP PHASE2:Hg19::chr1:186276427..186276448,+	p@chr1:186276427..186276448, +
7.54e-30	FFCP PHASE1:Hg19::chr1:186276427..186276448,+	p@chr1:186276427..186276448, +
8.12e-28	FFCP PHASE2:Hg19::chr7:80373118..80373135,-	p21@SEMA3C
8.12e-28	FFCP PHASE1:Hg19::chr7:80373118..80373135,-	p21@SEMA3C
1.39e-27	FFCP PHASE2:Hg19::chr20:48160907..48160918,-	p@chr20:48160907..48160918, -
1.39e-27	FFCP PHASE1:Hg19::chr20:48160907..48160918,-	p@chr20:48160907..48160918, -
1.82e-27	FFCP PHASE2:Hg19::chr20:43343646..43343655,+	p7@WISP2
1.82e-27	FFCP PHASE1:Hg19::chr20:43343646..43343655,+	p7@WISP2
1.82e-27	FFCP PHASE2:Hg19::chr3:156877038..156877058,-	p35@CCNL1
1.82e-27	FFCP PHASE1:Hg19::chr3:156877038..156877058,-	p35@CCNL1
1.82e-27	FFCP PHASE2:Hg19::chr1:142537912..142537938,-	p@chr1:142537912..142537938, -
1.82e-27	FFCP PHASE1:Hg19::chr1:142537912..142537938,-	p@chr1:142537912..142537938, -
2.08e-27	FFCP PHASE1:Hg19::chr1:142539672..142539687,-	p@chr1:142539672..142539687, -
2.08e-27	FFCP PHASE2:Hg19::chr6:1609602..1609636,-	p@chr6:1609602..1609636, -
2.08e-27	FFCP PHASE1:Hg19::chr6:1609602..1609636,-	p@chr6:1609602..1609636, -
2.08e-27	FFCP PHASE2:Hg19::chr1:142539672..142539687,-	p@chr1:142539672..142539687, -
2.38e-27	FFCP PHASE2:Hg19::chr21:39705323..39705334,-	p2@ENST00000436845
2.38e-27	FFCP PHASE1:Hg19::chr21:39705323..39705334,-	p2@ENST00000436845
3.11e-27	FFCP PHASE2:Hg19::chr6:31918397..31918412,+	p15@CFB
3.11e-27	FFCP PHASE2:Hg19::chr16:15680784..15680797,+	p@chr16:15680784..15680797, +
3.11e-27	FFCP PHASE1:Hg19::chr6:31918397..31918412,+	p15@CFB
3.11e-27	FFCP PHASE1:Hg19::chr16:15680784..15680797,+	p@chr16:15680784..15680797, +
4.07e-27	FFCP PHASE1:Hg19::chr8:70476088..70476102,+	p21@SULF1
4.07e-27	FFCP PHASE2:Hg19::chr8:70476088..70476102,+	p21@SULF1

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