MCL coexpression mm9:3349
From FANTOM5_SSTAR
Phase1 CAGE Peaks
| Short description | |
|---|---|
| Mm9::chr2:38142694..38142715,- | p2@Dennd1a |
| Mm9::chr2:38142729..38142745,- | p3@Dennd1a |
| Mm9::chr3:135148569..135148632,+ | p1@Manba |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0004567 | beta-mannosidase activity | 0.00690297485344875 |
| GO:0048488 | synaptic vesicle endocytosis | 0.0172508185679887 |
| GO:0006516 | glycoprotein catabolic process | 0.0172508185679887 |
| GO:0017124 | SH3 domain binding | 0.0172508185679887 |
| GO:0015923 | mannosidase activity | 0.0172508185679887 |
| GO:0030665 | clathrin coated vesicle membrane | 0.0172508185679887 |
| GO:0048489 | synaptic vesicle transport | 0.0224193037463458 |
| GO:0030662 | coated vesicle membrane | 0.0224193037463458 |
| GO:0030659 | cytoplasmic vesicle membrane | 0.0280618538186314 |
| GO:0030425 | dendrite | 0.0280618538186314 |
| GO:0044433 | cytoplasmic vesicle part | 0.0280618538186314 |
| GO:0019904 | protein domain specific binding | 0.0280618538186314 |
| GO:0012506 | vesicle membrane | 0.0280618538186314 |
| GO:0043025 | cell soma | 0.0280618538186314 |
| GO:0030136 | clathrin-coated vesicle | 0.0339865740550138 |
| GO:0030135 | coated vesicle | 0.0352437618835035 |
| GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds | 0.0352437618835035 |
| GO:0009100 | glycoprotein metabolic process | 0.0374829962895571 |
| GO:0016798 | hydrolase activity, acting on glycosyl bonds | 0.0391229485738048 |
| GO:0043005 | neuron projection | 0.0399111231992233 |
| GO:0010324 | membrane invagination | 0.0486697011754536 |
| GO:0006897 | endocytosis | 0.0486697011754536 |
| GO:0005764 | lysosome | 0.0486697011754536 |
| GO:0000323 | lytic vacuole | 0.0486697011754536 |
| GO:0016023 | cytoplasmic membrane-bound vesicle | 0.0493369173761718 |
| GO:0005773 | vacuole | 0.0493369173761718 |
| GO:0031988 | membrane-bound vesicle | 0.0493369173761718 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>
| Ontology term | p-value | n |
|---|---|---|
| endoderm-derived structure | 3.98e-09 | 118 |
| endoderm | 3.98e-09 | 118 |
| presumptive endoderm | 3.98e-09 | 118 |
| digestive tract diverticulum | 9.04e-09 | 23 |
| sac | 9.04e-09 | 23 |
| trunk region element | 1.14e-08 | 79 |
| subdivision of digestive tract | 1.23e-08 | 114 |
| liver | 1.39e-08 | 22 |
| epithelial sac | 1.39e-08 | 22 |
| digestive gland | 1.39e-08 | 22 |
| epithelium of foregut-midgut junction | 1.39e-08 | 22 |
| anatomical boundary | 1.39e-08 | 22 |
| hepatobiliary system | 1.39e-08 | 22 |
| foregut-midgut junction | 1.39e-08 | 22 |
| hepatic diverticulum | 1.39e-08 | 22 |
| liver primordium | 1.39e-08 | 22 |
| septum transversum | 1.39e-08 | 22 |
| liver bud | 1.39e-08 | 22 |
| endo-epithelium | 1.43e-08 | 69 |
| digestive system | 2.51e-08 | 116 |
| digestive tract | 2.51e-08 | 116 |
| primitive gut | 2.51e-08 | 116 |
| exocrine gland | 4.44e-08 | 25 |
| exocrine system | 4.44e-08 | 25 |
| subdivision of trunk | 1.48e-07 | 66 |
| foregut | 1.53e-07 | 80 |
| abdomen element | 2.57e-07 | 49 |
| abdominal segment element | 2.57e-07 | 49 |
| abdominal segment of trunk | 2.57e-07 | 49 |
| abdomen | 2.57e-07 | 49 |
| trunk | 4.02e-07 | 90 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
| MA0003.1 | 3.77865 |
| MA0004.1 | 0.801718 |
| MA0006.1 | 0.60285 |
| MA0007.1 | 0.784593 |
| MA0009.1 | 1.27673 |
| MA0014.1 | 0.416365 |
| MA0017.1 | 0.635031 |
| MA0019.1 | 1.08369 |
| MA0024.1 | 1.23079 |
| MA0025.1 | 1.51835 |
| MA0027.1 | 2.9431 |
| MA0028.1 | 0.61552 |
| MA0029.1 | 1.20789 |
| MA0030.1 | 1.21482 |
| MA0031.1 | 1.17722 |
| MA0038.1 | 0.963265 |
| MA0040.1 | 1.28983 |
| MA0041.1 | 0.714279 |
| MA0042.1 | 0.69885 |
| MA0043.1 | 1.3775 |
| MA0046.1 | 1.31428 |
| MA0048.1 | 0.932001 |
| MA0050.1 | 0.845669 |
| MA0051.1 | 0.973068 |
| MA0052.1 | 1.29825 |
| MA0055.1 | 3.14815 |
| MA0056.1 | 0 |
| MA0057.1 | 0.337566 |
| MA0058.1 | 0.690848 |
| MA0059.1 | 0.705317 |
| MA0060.1 | 0.502699 |
| MA0061.1 | 0.5406 |
| MA0063.1 | 0 |
| MA0066.1 | 0.951196 |
| MA0067.1 | 1.63197 |
| MA0068.1 | 0.343188 |
| MA0069.1 | 1.29861 |
| MA0070.1 | 1.28847 |
| MA0071.1 | 0.844726 |
| MA0072.1 | 1.2796 |
| MA0073.1 | 0.0430758 |
| MA0074.1 | 0.911576 |
| MA0076.1 | 0.657929 |
| MA0077.1 | 1.2569 |
| MA0078.1 | 1.0091 |
| MA0081.1 | 0.732313 |
| MA0083.1 | 1.37668 |
| MA0084.1 | 1.96428 |
| MA0087.1 | 1.33189 |
| MA0088.1 | 1.40099 |
| MA0089.1 | 0 |
| MA0090.1 | 0.762482 |
| MA0091.1 | 0.816659 |
| MA0092.1 | 0.762845 |
| MA0093.1 | 0.62555 |
| MA0095.1 | 0 |
| MA0098.1 | 0 |
| MA0100.1 | 0.89873 |
| MA0101.1 | 0.71579 |
| MA0103.1 | 0.647985 |
| MA0105.1 | 0.405648 |
| MA0106.1 | 1.01755 |
| MA0107.1 | 0.640607 |
| MA0108.2 | 1.10817 |
| MA0109.1 | 0 |
| MA0111.1 | 0.778753 |
| MA0113.1 | 0.986839 |
| MA0114.1 | 0.537669 |
| MA0115.1 | 1.38041 |
| MA0116.1 | 0.602598 |
| MA0117.1 | 1.34691 |
| MA0119.1 | 0.716476 |
| MA0122.1 | 1.36752 |
| MA0124.1 | 1.57762 |
| MA0125.1 | 1.5017 |
| MA0130.1 | 0 |
| MA0131.1 | 1.07881 |
| MA0132.1 | 0 |
| MA0133.1 | 0 |
| MA0135.1 | 1.4152 |
| MA0136.1 | 0.933582 |
| MA0139.1 | 1.16863 |
| MA0140.1 | 0.898603 |
| MA0141.1 | 0.671467 |
| MA0142.1 | 1.16183 |
| MA0143.1 | 1.00467 |
| MA0144.1 | 1.33779 |
| MA0145.1 | 1.44606 |
| MA0146.1 | 2.07553 |
| MA0147.1 | 1.37022 |
| MA0148.1 | 0.820161 |
| MA0149.1 | 2.8784 |
| MA0062.2 | 0.412742 |
| MA0035.2 | 0.903829 |
| MA0039.2 | 1.10518 |
| MA0138.2 | 1.07027 |
| MA0002.2 | 0.466067 |
| MA0137.2 | 1.60348 |
| MA0104.2 | 0.48458 |
| MA0047.2 | 0.962424 |
| MA0112.2 | 1.44603 |
| MA0065.2 | 0.292912 |
| MA0150.1 | 0.784464 |
| MA0151.1 | 0 |
| MA0152.1 | 0.962542 |
| MA0153.1 | 1.43238 |
| MA0154.1 | 0.925147 |
| MA0155.1 | 0.312898 |
| MA0156.1 | 0.656895 |
| MA0157.1 | 1.12772 |
| MA0158.1 | 0 |
| MA0159.1 | 0.569393 |
| MA0160.1 | 0.823568 |
| MA0161.1 | 0 |
| MA0162.1 | 2.19629 |
| MA0163.1 | 2.84458 |
| MA0164.1 | 0.933981 |
| MA0080.2 | 0.64167 |
| MA0018.2 | 0.944669 |
| MA0099.2 | 1.06348 |
| MA0079.2 | 4.46976 |
| MA0102.2 | 2.01714 |
| MA0258.1 | 0.520639 |
| MA0259.1 | 0.543506 |
| MA0442.1 | 0 |
