UBERON:0007245

Name:	nuclear complex of neuraxis
Namespace:	FANTOM
Definition:	"Internal gray matter component which consists of an assemblage of nuclei of neuraxis. Example: cerebellar nuclear complex, Vestibular nuclear complex.[FMA]" [FMA:84059, FMA:FMA]
Xrefs:	Expandlinks: FMA:84059
Comments:	todo - move existing complex classes currently under nucleus to be under this class

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data

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Parents

is_a:	UBERON:0002020(gray matter)

Children

is a:	UBERON:0002420 (basal ganglion)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology

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Human (Homo sapiens)

• 10037-101F1 (nucleus accumbens, adult, pool1)
• 10151-102I7 (amygdala, adult, donor10252)
• 10152-102I8 (putamen, adult, donor10252)
• 10158-103A5 (substantia nigra, adult, donor10252)
• 10161-103A8 (globus pallidus, adult, donor10252)
• 10164-103B2 (caudate nucleus, adult, donor10252)
• 10167-103B5 (amygdala - adult, donor10196)
• 10175-103C4 (globus pallidus - adult, donor10196)
• 10176-103C5 (putamen, adult, donor10196)
• 10177-103C6 (caudate nucleus - adult, donor10196)

... further results Mouse (Mus musculus)

• 10037-101F1 (nucleus accumbens, adult, pool1)
• 10151-102I7 (amygdala, adult, donor10252)
• 10152-102I8 (putamen, adult, donor10252)
• 10158-103A5 (substantia nigra, adult, donor10252)
• 10161-103A8 (globus pallidus, adult, donor10252)
• 10164-103B2 (caudate nucleus, adult, donor10252)
• 10167-103B5 (amygdala - adult, donor10196)
• 10175-103C4 (globus pallidus - adult, donor10196)
• 10176-103C5 (putamen, adult, donor10196)
• 10177-103C6 (caudate nucleus - adult, donor10196)

... further results

Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0007245 (nuclear complex of neuraxis), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

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P-value	FFCP	Short description

P-value	FFCP	Short description
1.82e-133	FFCP PHASE2:Hg19::chr18:11751466..11751475,+	p22@GNAL
1.82e-133	FFCP PHASE1:Hg19::chr18:11751466..11751475,+	p22@GNAL
1.42e-130	FFCP PHASE2:Hg19::chr15:40582949..40582989,+	p@chr15:40582949..40582989, +
1.42e-130	FFCP PHASE1:Hg19::chr15:40582949..40582989,+	p@chr15:40582949..40582989, +
1.21e-118	FFCP PHASE1:Hg19::chr3:35722978..35722999,+	p28@ARPP21
1.21e-118	FFCP PHASE2:Hg19::chr3:35722978..35722999,+	p28@ARPP21
3.02e-112	FFCP PHASE2:Hg19::chr13:98995904..98995913,+	p@chr13:98995904..98995913, +
3.02e-112	FFCP PHASE1:Hg19::chr13:98995904..98995913,+	p@chr13:98995904..98995913, +
3.66e-112	FFCP PHASE2:Hg19::chr11:80886203..80886231,+	p@chr11:80886203..80886231, +
3.66e-112	FFCP PHASE1:Hg19::chr11:80886203..80886231,+	p@chr11:80886203..80886231, +
6.51e-112	FFCP PHASE1:Hg19::chr2:7112752..7112770,+	p@chr2:7112752..7112770, +
6.51e-112	FFCP PHASE2:Hg19::chr2:7112752..7112770,+	p@chr2:7112752..7112770, +
7.88e-112	FFCP PHASE1:Hg19::chr22:27727810..27727817,+	p3@ENST00000413244
7.88e-112	FFCP PHASE2:Hg19::chr22:27727810..27727817,+	p3@ENST00000413244
4.6e-109	FFCP PHASE1:Hg19::chr15:35546024..35546035,-	p@chr15:35546024..35546035, -
4.6e-109	FFCP PHASE1:Hg19::chr2:3853961..3853984,+	p@chr2:3853961..3853984, +
4.6e-109	FFCP PHASE2:Hg19::chr15:35546024..35546035,-	p@chr15:35546024..35546035, -
4.6e-109	FFCP PHASE2:Hg19::chr2:3853961..3853984,+	p@chr2:3853961..3853984, +
4.6e-109	FFCP PHASE1:Hg19::chr17:19390211..19390223,+	p@chr17:19390211..19390223, +
4.6e-109	FFCP PHASE2:Hg19::chr19:719510..719520,+	p@chr19:719510..719520, +
4.6e-109	FFCP PHASE1:Hg19::chr19:719510..719520,+	p@chr19:719510..719520, +
4.6e-109	FFCP PHASE2:Hg19::chr17:19390211..19390223,+	p@chr17:19390211..19390223, +
4.01e-107	FFCP PHASE1:Hg19::chr18:11751516..11751523,+	p17@GNAL
4.01e-107	FFCP PHASE2:Hg19::chr18:11751516..11751523,+	p17@GNAL
1.41e-106	FFCP PHASE1:Hg19::chr21:43917191..43917207,-	p@chr21:43917191..43917207, -
1.41e-106	FFCP PHASE2:Hg19::chr21:43917191..43917207,-	p@chr21:43917191..43917207, -
3.33e-98	FFCP PHASE2:Hg19::chr11:18765839..18765846,-	p10@PTPN5
3.33e-98	FFCP PHASE1:Hg19::chr11:18765839..18765846,-	p10@PTPN5
1.43e-97	FFCP PHASE2:Hg19::chr13:98995923..98995941,+	p@chr13:98995923..98995941, +
1.43e-97	FFCP PHASE1:Hg19::chr13:98995923..98995941,+	p@chr13:98995923..98995941, +
4.08e-91	FFCP PHASE1:Hg19::chr11:26497871..26497889,+	p@chr11:26497871..26497889, +
4.08e-91	FFCP PHASE2:Hg19::chr11:26497871..26497889,+	p@chr11:26497871..26497889, +
4.08e-91	FFCP PHASE2:Hg19::chr10:97261901..97261919,-	p@chr10:97261901..97261919, -
4.08e-91	FFCP PHASE1:Hg19::chr10:97261901..97261919,-	p@chr10:97261901..97261919, -
4.91e-91	FFCP PHASE2:Hg19::chr1:242372439..242372456,+	p1@ENST00000421878
4.91e-91	FFCP PHASE2:Hg19::chr22:24828830..24828842,+	p14@ADORA2A
4.91e-91	FFCP PHASE1:Hg19::chr1:242372439..242372456,+	p1@ENST00000421878
4.91e-91	FFCP PHASE2:Hg19::chr19:1236637..1236645,-	p@chr19:1236637..1236645, -
4.91e-91	FFCP PHASE1:Hg19::chr11:26495467..26495474,+	p8@ANO3
4.91e-91	FFCP PHASE1:Hg19::chr22:24828830..24828842,+	p14@ADORA2A
4.91e-91	FFCP PHASE1:Hg19::chr19:1236637..1236645,-	p@chr19:1236637..1236645, -
4.91e-91	FFCP PHASE2:Hg19::chr11:26495467..26495474,+	p8@ANO3
1.7e-89	FFCP PHASE1:Hg19::chr11:18765553..18765567,-	p7@PTPN5
1.7e-89	FFCP PHASE2:Hg19::chr1:174417095..174417131,+	p1@GPR52
1.7e-89	FFCP PHASE1:Hg19::chr1:174417095..174417131,+	p1@GPR52
1.7e-89	FFCP PHASE2:Hg19::chr11:18765553..18765567,-	p7@PTPN5
2.51e-89	FFCP PHASE1:Hg19::chr1:101003675..101003682,+	p5@GPR88
2.51e-89	FFCP PHASE2:Hg19::chr1:101003675..101003682,+	p5@GPR88
2.86e-89	FFCP PHASE1:Hg19::chr11:67174819..67174825,-	p14@PPP1CA
2.86e-89	FFCP PHASE2:Hg19::chr11:67174819..67174825,-	p14@PPP1CA
4.81e-88	FFCP PHASE2:Hg19::chr11:18765881..18765897,-	p3@PTPN5
4.81e-88	FFCP PHASE1:Hg19::chr11:18765881..18765897,-	p3@PTPN5
1.33e-87	FFCP PHASE1:Hg19::chr17:19390234..19390251,+	p@chr17:19390234..19390251, +
1.33e-87	FFCP PHASE2:Hg19::chr17:19390234..19390251,+	p@chr17:19390234..19390251, +
1.37e-87	FFCP PHASE2:Hg19::chr13:112726433..112726446,+	p@chr13:112726433..112726446, +
1.37e-87	FFCP PHASE1:Hg19::chr14:78638610..78638621,+	p@chr14:78638610..78638621, +
1.37e-87	FFCP PHASE1:Hg19::chr15:35546154..35546174,-	p@chr15:35546154..35546174, -
1.37e-87	FFCP PHASE2:Hg19::chr8:25281776..25281779,-	p1@GNRH1
1.37e-87	FFCP PHASE1:Hg19::chr7:22382758..22382765,-	p@chr7:22382758..22382765, -
1.37e-87	FFCP PHASE1:Hg19::chr2:152828264..152828299,-	p@chr2:152828264..152828299, -
1.37e-87	FFCP PHASE1:Hg19::chr7:29846088..29846091,+	p20@WIPF3
1.37e-87	FFCP PHASE1:Hg19::chr18:47967428..47967437,-	p@chr18:47967428..47967437, -
1.37e-87	FFCP PHASE2:Hg19::chr18:47967428..47967437,-	p@chr18:47967428..47967437, -
1.37e-87	FFCP PHASE1:Hg19::chr1:31352916..31352926,-	p@chr1:31352916..31352926, -
1.37e-87	FFCP PHASE1:Hg19::chr8:25281776..25281779,-	p1@GNRH1
1.37e-87	FFCP PHASE2:Hg19::chr7:22382758..22382765,-	p@chr7:22382758..22382765, -
1.37e-87	FFCP PHASE2:Hg19::chr12:6031299..6031315,-	p@chr12:6031299..6031315, -
1.37e-87	FFCP PHASE2:Hg19::chr8:19799565..19799589,-	p@chr8:19799565..19799589, -
1.37e-87	FFCP PHASE1:Hg19::chr8:19799565..19799589,-	p@chr8:19799565..19799589, -
1.37e-87	FFCP PHASE2:Hg19::chr15:35546154..35546174,-	p@chr15:35546154..35546174, -
1.37e-87	FFCP PHASE2:Hg19::chr1:31352916..31352926,-	p@chr1:31352916..31352926, -
1.37e-87	FFCP PHASE2:Hg19::chr14:78638610..78638621,+	p@chr14:78638610..78638621, +
1.37e-87	FFCP PHASE2:Hg19::chr2:152828264..152828299,-	p@chr2:152828264..152828299, -
1.37e-87	FFCP PHASE1:Hg19::chr13:112726433..112726446,+	p@chr13:112726433..112726446, +
1.37e-87	FFCP PHASE1:Hg19::chr12:6031299..6031315,-	p@chr12:6031299..6031315, -
1.37e-87	FFCP PHASE2:Hg19::chr7:29846088..29846091,+	p20@WIPF3
1.79e-87	FFCP PHASE2:Hg19::chr11:26495447..26495461,+	p5@ANO3
1.79e-87	FFCP PHASE1:Hg19::chr10:73313437..73313451,-	p@chr10:73313437..73313451, -
1.79e-87	FFCP PHASE2:Hg19::chr10:73313437..73313451,-	p@chr10:73313437..73313451, -
1.79e-87	FFCP PHASE1:Hg19::chr11:26495447..26495461,+	p5@ANO3
2.08e-87	FFCP PHASE1:Hg19::chr3:16851273..16851310,+	p@chr3:16851273..16851310, +
2.08e-87	FFCP PHASE2:Hg19::chr3:16851273..16851310,+	p@chr3:16851273..16851310, +
2.42e-87	FFCP PHASE1:Hg19::chr7:67899920..67899958,-	p@chr7:67899920..67899958, -
2.42e-87	FFCP PHASE2:Hg19::chr7:67899920..67899958,-	p@chr7:67899920..67899958, -
2.8e-87	FFCP PHASE2:Hg19::chr9:95569585..95569596,+	p@chr9:95569585..95569596, +
2.8e-87	FFCP PHASE1:Hg19::chr9:95569585..95569596,+	p@chr9:95569585..95569596, +
4.39e-83	FFCP PHASE2:Hg19::chr18:11751493..11751507,+	p12@GNAL
4.39e-83	FFCP PHASE1:Hg19::chr18:11751493..11751507,+	p12@GNAL
3.09e-79	FFCP PHASE1:Hg19::chr11:13461601..13461620,-	p5@BTBD10
3.09e-79	FFCP PHASE2:Hg19::chr11:13461601..13461620,-	p5@BTBD10
5.29e-79	FFCP PHASE2:Hg19::chr6:166076645..166076657,-	p@chr6:166076645..166076657, -
5.29e-79	FFCP PHASE1:Hg19::chr6:166076645..166076657,-	p@chr6:166076645..166076657, -
6.06e-79	FFCP PHASE2:Hg19::chr2:26781521..26781537,-	p2@OTOF
6.06e-79	FFCP PHASE1:Hg19::chr22:27727719..27727726,+	p2@ENST00000413244
6.06e-79	FFCP PHASE2:Hg19::chr11:18765589..18765610,-	p6@PTPN5
6.06e-79	FFCP PHASE2:Hg19::chr22:27727719..27727726,+	p2@ENST00000413244
6.06e-79	FFCP PHASE1:Hg19::chr2:26781521..26781537,-	p2@OTOF
6.06e-79	FFCP PHASE1:Hg19::chr11:18765589..18765610,-	p6@PTPN5
6.93e-79	FFCP PHASE2:Hg19::chr19:19640188..19640201,+	p@chr19:19640188..19640201, +
6.93e-79	FFCP PHASE1:Hg19::chr19:19640188..19640201,+	p@chr19:19640188..19640201, +

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