Coexpression cluster:C1162: Difference between revisions
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{{Coexpression_clusters | 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ribosome (sensu Eukaryota)!1.80412952534817e-08!6125;6191;6135;6128$GO:0044445!cytosolic part!3.89335864396034e-07!6125;6191;6135;6128$GO:0033279!ribosomal subunit!4.50106557389469e-07!6125;6191;6135;6128$GO:0019843!rRNA binding!4.50106557389469e-07!6125;6191;6135$GO:0005842!cytosolic large ribosomal subunit (sensu Eukaryota)!4.6083793122753e-07!6125;6135;6128$GO:0015934!large ribosomal subunit!7.85433413948777e-06!6125;6135;6128$GO:0005829!cytosol!8.99367102257202e-06!6125;6191;6135;6128$GO:0003735!structural constituent of ribosome!2.76395189313524e-05!6125;6191;6135;6128$GO:0005840!ribosome!3.48041401227949e-05!6125;6191;6135;6128$GO:0003723!RNA binding!5.48133301770672e-05!6125;6191;6135;6128$GO:0030529!ribonucleoprotein complex!9.14479151801551e-05!6125;6191;6135;6128$GO:0006412!translation!0.000105937742458961!6125;6191;6135;6128$GO:0009059!macromolecule biosynthetic process!0.000273606126740663!6125;6191;6135;6128$GO:0044249!cellular biosynthetic process!0.000593938698888462!6125;6191;6135;6128$GO:0010467!gene expression!0.00117137004948452!6233;6125;6191;6135;6128$GO:0044267!cellular protein metabolic process!0.00117327045102701!6233;6125;6191;6135;6128$GO:0044260!cellular macromolecule metabolic process!0.00117327045102701!6233;6125;6191;6135;6128$GO:0009058!biosynthetic process!0.00117327045102701!6125;6191;6135;6128$GO:0019538!protein metabolic process!0.00132208046366353!6233;6125;6191;6135;6128$GO:0043232!intracellular non-membrane-bound organelle!0.00199327017675962!6125;6191;6135;6128$GO:0043228!non-membrane-bound organelle!0.00199327017675962!6125;6191;6135;6128$GO:0008582!regulation of synaptic growth at neuromuscular junction!0.00202360627664!6233$GO:0051124!synaptic growth at neuromuscular junction!0.00202360627664!6233$GO:0042062!long-term strengthening of neuromuscular junction!0.00202360627664!6233$GO:0008097!5S rRNA binding!0.00291382148067808!6125$GO:0005737!cytoplasm!0.00328504115132846!6233;6125;6191;6135;6128$GO:0032991!macromolecular complex!0.0047323211441893!6125;6191;6135;6128$GO:0050806!positive regulation of synaptic transmission!0.00520233369326765!6233$GO:0044446!intracellular organelle part!0.00541624347566376!6125;6191;6135;6128$GO:0044422!organelle part!0.00541624347566376!6125;6191;6135;6128$GO:0051971!positive regulation of transmission of nerve impulse!0.0054817063055444!6233$GO:0031646!positive regulation of neurological process!0.00606867467450403!6233$GO:0007528!neuromuscular junction development!0.00721681283175408!6233$GO:0044444!cytoplasmic part!0.00721681283175408!6125;6191;6135;6128$GO:0030433!ER-associated protein catabolic process!0.00741595907656725!6233$GO:0006515!misfolded or incompletely synthesized protein catabolic process!0.00741595907656725!6233$GO:0048167!regulation of synaptic plasticity!0.0102161128062905!6233$GO:0050804!regulation of synaptic transmission!0.0102161128062905!6233$GO:0051969!regulation of transmission of nerve impulse!0.0109171849772188!6233$GO:0050803!regulation of synapse structure and activity!0.0109171849772188!6233$GO:0043229!intracellular organelle!0.0125611320158036!6233;6125;6191;6135;6128$GO:0043226!organelle!0.0125611320158036!6233;6125;6191;6135;6128$GO:0043161!proteasomal ubiquitin-dependent protein catabolic process!0.0129726795143152!6233$GO:0031644!regulation of neurological process!0.0134724526218766!6233$GO:0007416!synaptogenesis!0.0134724526218766!6233$GO:0043170!macromolecule metabolic process!0.0136164574474217!6233;6125;6191;6135;6128$GO:0005843!cytosolic small ribosomal subunit (sensu Eukaryota)!0.0175335600722431!6191$GO:0003676!nucleic acid binding!0.0181231096858235!6125;6191;6135;6128$GO:0048589!developmental growth!0.0182986050132503!6233$GO:0050808!synapse organization and biogenesis!0.0188997388298272!6233$GO:0048741!skeletal muscle fiber development!0.0195672790731445!6233$GO:0048747!muscle fiber development!0.0195672790731445!6233$GO:0044237!cellular metabolic process!0.0224350864349877!6233;6125;6191;6135;6128$GO:0044238!primary metabolic process!0.0228668393165134!6233;6125;6191;6135;6128$GO:0044424!intracellular part!0.0242061947206519!6233;6125;6191;6135;6128$GO:0007411!axon guidance!0.0242061947206519!6233$GO:0007519!skeletal muscle development!0.0284344745885562!6233$GO:0016567!protein ubiquitination!0.0304359394801792!6233$GO:0032446!protein modification by small protein conjugation!0.0315521008867531!6233$GO:0043062!extracellular structure organization and biogenesis!0.0338328528209046!6233$GO:0014706!striated muscle development!0.0348546835516022!6233$GO:0005622!intracellular!0.0432642044174568!6233;6125;6191;6135;6128$GO:0007409!axonogenesis!0.0436523682379881!6233$GO:0048667!neuron morphogenesis during differentiation!0.0442085182750772!6233$GO:0048812!neurite morphogenesis!0.0442085182750772!6233$GO:0015935!small ribosomal subunit!0.0442085182750772!6191$GO:0000904!cellular morphogenesis during differentiation!0.0453348748357801!6233$GO:0031175!neurite development!0.0478334177117967!6233|id=C1162|kegg_enrichment=hsa03010;Ribosome;2.37E-07|ontology_enrichment_celltype=CL:0000548!1.37e-38!679;CL:0000255!1.37e-38!679;CL:0002321!1.03e-24!250;CL:0000003!5.24e-23!722;CL:0000066!1.62e-21!253;CL:0002371!5.05e-12!588;CL:0000393!2.70e-11!61;CL:0000211!2.70e-11!61;CL:0000055!9.70e-11!106;CL:0000222!1.55e-10!121;CL:0000680!1.88e-10!58;CL:0000056!1.88e-10!58;CL:0000355!1.88e-10!58;CL:0000076!3.11e-10!63;CL:0000187!8.00e-10!55;CL:0000183!4.24e-08!59;CL:0000192!2.46e-07!43;CL:0000514!2.46e-07!43;CL:0002076!3.64e-07!42;CL:0000359!4.59e-07!32|ontology_enrichment_disease=DOID:14566!9.63e-30!239;DOID:162!2.20e-28!235;DOID:0050687!2.43e-14!143;DOID:305!1.14e-13!106;DOID:0050686!6.96e-13!137;DOID:2531!7.83e-08!51;DOID:0060083!7.83e-08!51|ontology_enrichment_uberon=UBERON:0000490!1.35e-12!148;UBERON:0002329!3.51e-11!71;UBERON:0003059!3.51e-11!71;UBERON:0007282!3.51e-11!71;UBERON:0004290!3.51e-11!71;UBERON:0009618!3.51e-11!71;UBERON:0003077!1.08e-10!72;UBERON:0007285!1.08e-10!72;UBERON:0007524!1.51e-10!73;UBERON:0000486!1.92e-10!83;UBERON:0007503!4.07e-10!78;UBERON:0001134!9.85e-09!62;UBERON:0002036!9.85e-09!62;UBERON:0003082!9.85e-09!62;UBERON:0002100!5.06e-08!199;UBERON:0002385!8.51e-08!64;UBERON:0001015!8.51e-08!64;UBERON:0000383!8.51e-08!64;UBERON:0001637!1.05e-07!42;UBERON:0003509!1.05e-07!42;UBERON:0004572!1.05e-07!42;UBERON:0000475!1.13e-07!264;UBERON:0005256!1.80e-07!122;UBERON:0001737!5.29e-07!9;UBERON:0003102!5.79e-07!99|pathway_enrichment=3.11437028550525e-13;1.04170377464436e-10;5;92;Ribosome (KEGG):03010!3.29132314263622e-13;1.04170377464436e-10;5;93;Cytoplasmic Ribosomal Proteins (Wikipathways):WP477!1.1591439383194e-10;1.22289685492696e-08;5;296;Metabolism of proteins (Reactome):REACT_17015!9.29699977867239e-13;1.96166695329987e-10;5;114;Regulation of beta-cell development (Reactome):REACT_13698!6.81527814787627e-10;5.3925888345071e-08;5;421;Gene Expression (Reactome):REACT_71!1.5108164748526e-10;1.36620975511671e-08;5;312;Diabetes pathways (Reactome):REACT_15380!2.94043896828612e-12;3.72259573385023e-10;5;143;Influenza Infection (Reactome):REACT_6167!2.45472569124687e-12;3.72259573385023e-10;5;138;{RPS27A,138} (Static Module):NA|tf_chipseq_enrich=BCLAF1#9774;4:12.3729414914982:0.00014216266196968:0.00185128756277449!ELF1#1997;6:3.64979825040646:0.000937747978262069:0.00678942537966809!ELK4#2005;4:9.27753237626744:0.000432817858966577:0.00404176183589148!ETS1#2113;4:5.55929195554419:0.00302256447530346:0.0160492964175209!GABPB1#2553;6:6.05801471672758:4.93271023131083e-05:0.000853632682432265!GTF2B#2959;6:27.3804256579922:6.39564885927993e-09:5.05261097741555e-07!GTF2F1#2962;6:10.9197093229351:1.52580683448537e-06:5.86722164899918e-05!HEY1#23462;6:3.46295232266204:0.00126789009587212:0.00850518168943341!KAT2A#2648;3:264.038571428571:1.47466334870275e-07:8.31151459660908e-06!MAX#4149;6:5.53076186486325:8.40673768319711e-05:0.00126166299309588!MXI1#4601;4:5.69232664500531:0.00276690540539156:0.0151612189734359!MYC#4609;6:4.47624160423663:0.000288361195091082:0.00306369835748906!NFKB1#4790;6:4.70405436359472:0.00021611506140197:0.00247677393808409!NRF1#4899;5:8.72162817693636:6.71450045004423e-05:0.00107340534593934!POU2F2#5452;6:7.80524919235073:1.11144903558223e-05:0.000284576184915844!RAD21#5885;4:5.91716222597504:0.00239318493722796:0.0135535947974162!RDBP#7936;3:65.8450302814393:9.4409612230599e-06:0.000250955599179219!REST#5978;5:6.89287765437716:0.000209438858484651:0.00243852674930641!RFX5#5993;5:8.60565059085364:7.16524263203101e-05:0.00112734374095614!SIN3A#25942;6:4.63618690869869:0.000235167814635783:0.00256535318495368!SIX5#147912;4:9.76383734597657:0.000355537135106872:0.00355874476264391!SMC3#9126;4:8.59710448281877:0.000579846628016137:0.00486649003402261!SP2#6668;4:14.9448745679112:6.81071539656055e-05:0.00108778759030645!SPI1#6688;4:4.68818486201299:0.00568568052914417:0.0256648134495954!SRF#6722;3:5.91307639807192:0.0106686813016745:0.0393914447594423!STAT2#6773;2:18.6467917675545:0.00468275705257902:0.0220935337827205!TAF1#6872;6:2.86546824492454:0.00372833020747146:0.0185854173327341!TAF7#6879;6:9.79977377564907:2.89681485118392e-06:9.9454453071268e-05!TBP#6908;6:3.17723201751119:0.00207411205185266:0.0120183193843453!TCF12#6938;6:9.1152556304455:4.4461156654571e-06:0.000139109608743162!YY1#7528;6:4.20957492844616:0.00041168337886575:0.00392190097649914!ZNF143#7702;6:11.5721799019096:1.08146108094101e-06:4.49628637867825e-05!ZNF263#10127;5:5.8727440264362:0.000451394263989067:0.00419796665509832!ZZZ3#26009;3:102.605662472243:2.50907428413451e-06:8.831992219775e-05|tfbs_overrepresentation=0.31043,0.131575,0.564335,0.107813,0.405466,0.547045,0.0974871,0.131367,0.0746874,0.0589549,0.295561,0.448908,0.386236,0.269614,0.313114,0.138515,0.298536,0.214302,0.119001,0.234193,0.385995,0.282418,0.180923,0.20757,0.0943256,0.432377,0.422025,0.199011,0.303793,0.204444,0.414424,0.246136,0.0415685,0.42006,0.148393,0.186108,0.934067,0.097401,0.258596,0.148774,0.210798,0.0564873,0.296737,0.377815,0.259708,0.0825288,0.0864669,0.373342,0.240639,0.260266,0.323223,0.12188,0.156121,0.203677,0.403772,0.0873518,0.232986,0.427667,0.173296,0.229205,0.0673274,0.314503,0.235283,0.168316,0.122724,0.113864,0.637,0.134457,0.189423,0.34721,0.670888,0.150845,0.195543,0.0361929,0.0173573,0.0394864,0.210826,0.0989984,0.0847661,0.0168408,0.209062,0.451469,0.0963703,0.247724,0.552245,0.491847,0.143736,0.421411,0.643105,0.140328,0.18877,0.111901,0.208559,0.107066,0.188008,0.248084,0.0574186,0.322402,0.203166,0.526481,0.129026,0.529658,0.300234,0.0843602,0.438429,0.0929061,0.149379,0.618184,0.0520139,0.519136,0.0813816,0.0775356,0.314757,0.0407805,0.220427,0.0769904,0.0468147,0.127234,0.294794,0.184794,0.346582,0.110185,0.296899,0.188824,0.222747,0.365096,0.198942,0.034178,0.185876,0.286955,0.133529,0.165976,0.128445,0.0523619,0.269253,0.234279,0.144853,0.124383,0.0754012,0.00920461,0.052339,0.272785,0.412653,0.326814,0.879733,0.154324,0.215565,0.1856,0.0885156,0.259543,0.406997,0.30366,0.371915,0.0609284,0.0968299,0.253074,0.165818,0.453904,0.116496,0.0769293,0.452804,0.208356,0.251281,0.311437,0.525489,0.246608,0.0909267,0.272323,0.0916381,0.582261,0.370083,0.292316,0.766596,0.121785,0.17666,0.197691,0.297301,0.373889,0.367859,0.0811784,0.332099,0.262763,0.0627829,0.249166,0.0141856,0.255634,0.376054,0.0912436,0.18278,0.35905,0.232364,0.38363,0.263667,0.45461,0.243403,0.0058736,0.173147,0.135052,0.150784,0.237426,0.196091,0.135293,0.0704675,0.135734,0.289872,0.503773,0.525644,0.319069,0.102289,0.367697,0.103767,0.226759,0.260173,0.243859,0.58295,0.350868,0.341984,0.219863,0.140859,0.224003,0.300341,0.662833,0.32693,0.336135,0.163924,0.270849,0.294471,0.189218,0.135411,0.134214,0.860233,0.678094,0.0949171,0.169481,0.209657,0.204086,0.106746,0.509502,0.340697,0.0197309,0.375058,0.0805866,0.214704,0.183242,0.25057,0.0470426,0.179951,0.241366,0.0249004,0.252043,0.332484,0.37985,0.380877,0.213951,0.214075,0.333636,0.232558,0.409093,0.154888,0.604062,0.138561,0.0751959,0.0659537,0.273737,0.0786852,0.179028,0.179229,0.201771,0.254117,0.16741,0.532883,0.141494,0.496492,0.748734,0.190495,0.0865316,0.27777,0.607792,0.0755362,0.69091,0.419083,0.575229,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Latest revision as of 11:39, 17 September 2013
Full id: C1162_embryonic_iPS_Keratinocyte_giant_teratocarcinoma_acute_chronic
Phase1 CAGE Peaks
Hg19::chr12:112847354..112847457,- | p1@RPL6 |
Hg19::chr1:24018269..24018274,+ | p2@RPL11 |
Hg19::chr1:93297622..93297635,+ | p2@RPL5 |
Hg19::chr2:55459786..55459807,+ | p2@RPS27A |
Hg19::chr3:185136568..185136602,- | p1@ENST00000422486 |
Hg19::chrX:71497077..71497133,- | p1@RPS4X |
Hg19::chrX:71497148..71497163,- | p3@RPS4X |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
p.value | FDR | nGenes | nPathway | Name |
---|---|---|---|---|
3.11437028550525e-13 | 1.04170377464436e-10 | 5 | 92 | Ribosome (KEGG):03010 |
3.29132314263622e-13 | 1.04170377464436e-10 | 5 | 93 | Cytoplasmic Ribosomal Proteins (Wikipathways):WP477 |
1.1591439383194e-10 | 1.22289685492696e-08 | 5 | 296 | Metabolism of proteins (Reactome):REACT_17015 |
9.29699977867239e-13 | 1.96166695329987e-10 | 5 | 114 | Regulation of beta-cell development (Reactome):REACT_13698 |
6.81527814787627e-10 | 5.3925888345071e-08 | 5 | 421 | Gene Expression (Reactome):REACT_71 |
1.5108164748526e-10 | 1.36620975511671e-08 | 5 | 312 | Diabetes pathways (Reactome):REACT_15380 |
2.94043896828612e-12 | 3.72259573385023e-10 | 5 | 143 | Influenza Infection (Reactome):REACT_6167 |
2.45472569124687e-12 | 3.72259573385023e-10 | 5 | 138 | {RPS27A,138} (Static Module):NA |
Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0005830 | cytosolic ribosome (sensu Eukaryota) | 1.80412952534817e-08 |
GO:0044445 | cytosolic part | 3.89335864396034e-07 |
GO:0033279 | ribosomal subunit | 4.50106557389469e-07 |
GO:0019843 | rRNA binding | 4.50106557389469e-07 |
GO:0005842 | cytosolic large ribosomal subunit (sensu Eukaryota) | 4.6083793122753e-07 |
GO:0015934 | large ribosomal subunit | 7.85433413948777e-06 |
GO:0005829 | cytosol | 8.99367102257202e-06 |
GO:0003735 | structural constituent of ribosome | 2.76395189313524e-05 |
GO:0005840 | ribosome | 3.48041401227949e-05 |
GO:0003723 | RNA binding | 5.48133301770672e-05 |
GO:0030529 | ribonucleoprotein complex | 9.14479151801551e-05 |
GO:0006412 | translation | 0.000105937742458961 |
GO:0009059 | macromolecule biosynthetic process | 0.000273606126740663 |
GO:0044249 | cellular biosynthetic process | 0.000593938698888462 |
GO:0010467 | gene expression | 0.00117137004948452 |
GO:0044267 | cellular protein metabolic process | 0.00117327045102701 |
GO:0044260 | cellular macromolecule metabolic process | 0.00117327045102701 |
GO:0009058 | biosynthetic process | 0.00117327045102701 |
GO:0019538 | protein metabolic process | 0.00132208046366353 |
GO:0043232 | intracellular non-membrane-bound organelle | 0.00199327017675962 |
GO:0043228 | non-membrane-bound organelle | 0.00199327017675962 |
GO:0008582 | regulation of synaptic growth at neuromuscular junction | 0.00202360627664 |
GO:0051124 | synaptic growth at neuromuscular junction | 0.00202360627664 |
GO:0042062 | long-term strengthening of neuromuscular junction | 0.00202360627664 |
GO:0008097 | 5S rRNA binding | 0.00291382148067808 |
GO:0005737 | cytoplasm | 0.00328504115132846 |
GO:0032991 | macromolecular complex | 0.0047323211441893 |
GO:0050806 | positive regulation of synaptic transmission | 0.00520233369326765 |
GO:0044446 | intracellular organelle part | 0.00541624347566376 |
GO:0044422 | organelle part | 0.00541624347566376 |
GO:0051971 | positive regulation of transmission of nerve impulse | 0.0054817063055444 |
GO:0031646 | positive regulation of neurological process | 0.00606867467450403 |
GO:0007528 | neuromuscular junction development | 0.00721681283175408 |
GO:0044444 | cytoplasmic part | 0.00721681283175408 |
GO:0030433 | ER-associated protein catabolic process | 0.00741595907656725 |
GO:0006515 | misfolded or incompletely synthesized protein catabolic process | 0.00741595907656725 |
GO:0048167 | regulation of synaptic plasticity | 0.0102161128062905 |
GO:0050804 | regulation of synaptic transmission | 0.0102161128062905 |
GO:0051969 | regulation of transmission of nerve impulse | 0.0109171849772188 |
GO:0050803 | regulation of synapse structure and activity | 0.0109171849772188 |
GO:0043229 | intracellular organelle | 0.0125611320158036 |
GO:0043226 | organelle | 0.0125611320158036 |
GO:0043161 | proteasomal ubiquitin-dependent protein catabolic process | 0.0129726795143152 |
GO:0031644 | regulation of neurological process | 0.0134724526218766 |
GO:0007416 | synaptogenesis | 0.0134724526218766 |
GO:0043170 | macromolecule metabolic process | 0.0136164574474217 |
GO:0005843 | cytosolic small ribosomal subunit (sensu Eukaryota) | 0.0175335600722431 |
GO:0003676 | nucleic acid binding | 0.0181231096858235 |
GO:0048589 | developmental growth | 0.0182986050132503 |
GO:0050808 | synapse organization and biogenesis | 0.0188997388298272 |
GO:0048741 | skeletal muscle fiber development | 0.0195672790731445 |
GO:0048747 | muscle fiber development | 0.0195672790731445 |
GO:0044237 | cellular metabolic process | 0.0224350864349877 |
GO:0044238 | primary metabolic process | 0.0228668393165134 |
GO:0044424 | intracellular part | 0.0242061947206519 |
GO:0007411 | axon guidance | 0.0242061947206519 |
GO:0007519 | skeletal muscle development | 0.0284344745885562 |
GO:0016567 | protein ubiquitination | 0.0304359394801792 |
GO:0032446 | protein modification by small protein conjugation | 0.0315521008867531 |
GO:0043062 | extracellular structure organization and biogenesis | 0.0338328528209046 |
GO:0014706 | striated muscle development | 0.0348546835516022 |
GO:0005622 | intracellular | 0.0432642044174568 |
GO:0007409 | axonogenesis | 0.0436523682379881 |
GO:0048667 | neuron morphogenesis during differentiation | 0.0442085182750772 |
GO:0048812 | neurite morphogenesis | 0.0442085182750772 |
GO:0015935 | small ribosomal subunit | 0.0442085182750772 |
GO:0000904 | cellular morphogenesis during differentiation | 0.0453348748357801 |
GO:0031175 | neurite development | 0.0478334177117967 |
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>
Ontology term | p-value | n |
---|---|---|
animal cell | 1.37e-38 | 679 |
eukaryotic cell | 1.37e-38 | 679 |
embryonic cell | 1.03e-24 | 250 |
native cell | 5.24e-23 | 722 |
epithelial cell | 1.62e-21 | 253 |
somatic cell | 5.05e-12 | 588 |
electrically responsive cell | 2.70e-11 | 61 |
electrically active cell | 2.70e-11 | 61 |
non-terminally differentiated cell | 9.70e-11 | 106 |
mesodermal cell | 1.55e-10 | 121 |
muscle precursor cell | 1.88e-10 | 58 |
myoblast | 1.88e-10 | 58 |
multi-potent skeletal muscle stem cell | 1.88e-10 | 58 |
squamous epithelial cell | 3.11e-10 | 63 |
muscle cell | 8.00e-10 | 55 |
contractile cell | 4.24e-08 | 59 |
smooth muscle cell | 2.46e-07 | 43 |
smooth muscle myoblast | 2.46e-07 | 43 |
endo-epithelial cell | 3.64e-07 | 42 |
vascular associated smooth muscle cell | 4.59e-07 | 32 |
Ontology term | p-value | n |
---|---|---|
unilaminar epithelium | 1.35e-12 | 148 |
somite | 3.51e-11 | 71 |
presomitic mesoderm | 3.51e-11 | 71 |
presumptive segmental plate | 3.51e-11 | 71 |
dermomyotome | 3.51e-11 | 71 |
trunk paraxial mesoderm | 3.51e-11 | 71 |
paraxial mesoderm | 1.08e-10 | 72 |
presumptive paraxial mesoderm | 1.08e-10 | 72 |
dense mesenchyme tissue | 1.51e-10 | 73 |
multilaminar epithelium | 1.92e-10 | 83 |
epithelial vesicle | 4.07e-10 | 78 |
skeletal muscle tissue | 9.85e-09 | 62 |
striated muscle tissue | 9.85e-09 | 62 |
myotome | 9.85e-09 | 62 |
trunk | 5.06e-08 | 199 |
muscle tissue | 8.51e-08 | 64 |
musculature | 8.51e-08 | 64 |
musculature of body | 8.51e-08 | 64 |
artery | 1.05e-07 | 42 |
arterial blood vessel | 1.05e-07 | 42 |
arterial system | 1.05e-07 | 42 |
organism subdivision | 1.13e-07 | 264 |
trunk mesenchyme | 1.80e-07 | 122 |
larynx | 5.29e-07 | 9 |
surface structure | 5.79e-07 | 99 |
Ontology term | p-value | n |
---|---|---|
disease of cellular proliferation | 9.63e-30 | 239 |
cancer | 2.20e-28 | 235 |
cell type cancer | 2.43e-14 | 143 |
carcinoma | 1.14e-13 | 106 |
organ system cancer | 6.96e-13 | 137 |
hematologic cancer | 7.83e-08 | 51 |
immune system cancer | 7.83e-08 | 51 |
Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
---|---|
MA0003.1 | 0.0137961 |
MA0004.1 | 0.502801 |
MA0006.1 | 0.341337 |
MA0007.1 | 0.483857 |
MA0009.1 | 0.973289 |
MA0014.1 | 0.187674 |
MA0017.1 | 0.380797 |
MA0019.1 | 0.652951 |
MA0024.1 | 0.867125 |
MA0025.1 | 1.10816 |
MA0027.1 | 2.59001 |
MA0028.1 | 2.53091 |
MA0029.1 | 0.886702 |
MA0030.1 | 0.875089 |
MA0031.1 | 0.809638 |
MA0038.1 | 0.60704 |
MA0040.1 | 0.892629 |
MA0041.1 | 0.521615 |
MA0042.1 | 0.48922 |
MA0043.1 | 0.973609 |
MA0046.1 | 0.962263 |
MA0048.1 | 0.382278 |
MA0050.1 | 1.22833 |
MA0051.1 | 1.46692 |
MA0052.1 | 0.896548 |
MA0055.1 | 0.158296 |
MA0056.1 | 0 |
MA0057.1 | 0.115382 |
MA0058.1 | 0.406232 |
MA0059.1 | 0.404929 |
MA0060.1 | 0.224688 |
MA0061.1 | 0.575931 |
MA0063.1 | 0 |
MA0066.1 | 0.607474 |
MA0067.1 | 1.29359 |
MA0068.1 | 0.162298 |
MA0069.1 | 0.958358 |
MA0070.1 | 0.947018 |
MA0071.1 | 0.567661 |
MA0072.1 | 0.942461 |
MA0073.1 | 0.000265001 |
MA0074.1 | 0.60198 |
MA0076.1 | 1.90063 |
MA0077.1 | 0.934645 |
MA0078.1 | 0.703614 |
MA0081.1 | 0.405093 |
MA0083.1 | 0.980893 |
MA0084.1 | 1.48179 |
MA0087.1 | 0.939982 |
MA0088.1 | 0.538456 |
MA0089.1 | 0 |
MA0090.1 | 0.436918 |
MA0091.1 | 0.505453 |
MA0092.1 | 0.467172 |
MA0093.1 | 0.344385 |
MA0095.1 | 0 |
MA0098.1 | 0 |
MA0100.1 | 0.621149 |
MA0101.1 | 0.918548 |
MA0103.1 | 0.332048 |
MA0105.1 | 0.104569 |
MA0106.1 | 0.648997 |
MA0107.1 | 1.3795 |
MA0108.2 | 0.806528 |
MA0109.1 | 0 |
MA0111.1 | 0.45062 |
MA0113.1 | 1.59862 |
MA0114.1 | 0.269076 |
MA0115.1 | 1.21667 |
MA0116.1 | 0.760835 |
MA0117.1 | 1.01134 |
MA0119.1 | 0.388712 |
MA0122.1 | 1.03753 |
MA0124.1 | 1.17486 |
MA0125.1 | 1.0901 |
MA0130.1 | 0 |
MA0131.1 | 1.71579 |
MA0132.1 | 0 |
MA0133.1 | 0 |
MA0135.1 | 1.00402 |
MA0136.1 | 0.614215 |
MA0139.1 | 1.04496 |
MA0140.1 | 0.564957 |
MA0141.1 | 0.403171 |
MA0142.1 | 0.777365 |
MA0143.1 | 0.66587 |
MA0144.1 | 0.254954 |
MA0145.1 | 0.0807715 |
MA0146.1 | 0.324987 |
MA0147.1 | 0.281049 |
MA0148.1 | 0.528066 |
MA0149.1 | 0.555119 |
MA0062.2 | 1.6882 |
MA0035.2 | 0.564239 |
MA0039.2 | 0.0553061 |
MA0138.2 | 0.704862 |
MA0002.2 | 0.611548 |
MA0137.2 | 0.95459 |
MA0104.2 | 0.223944 |
MA0047.2 | 0.636643 |
MA0112.2 | 0.0758925 |
MA0065.2 | 0.282161 |
MA0150.1 | 0.430951 |
MA0151.1 | 0 |
MA0152.1 | 0.571637 |
MA0153.1 | 1.07307 |
MA0154.1 | 0.102476 |
MA0155.1 | 0.071478 |
MA0156.1 | 0.36627 |
MA0157.1 | 0.749547 |
MA0158.1 | 0 |
MA0159.1 | 0.770207 |
MA0160.1 | 0.543522 |
MA0161.1 | 0 |
MA0162.1 | 0.0249953 |
MA0163.1 | 0.942271 |
MA0164.1 | 0.678332 |
MA0080.2 | 0.344472 |
MA0018.2 | 0.650405 |
MA0099.2 | 0.572 |
MA0079.2 | 0.000432051 |
MA0102.2 | 1.51913 |
MA0258.1 | 0.687127 |
MA0259.1 | 0.787775 |
MA0442.1 | 0 |
ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data
(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)
TF | #promoters | Enrichment | p-value | q-value |
---|---|---|---|---|
BCLAF1#9774 | 4 | 12.3729414914982 | 0.00014216266196968 | 0.00185128756277449 |
ELF1#1997 | 6 | 3.64979825040646 | 0.000937747978262069 | 0.00678942537966809 |
ELK4#2005 | 4 | 9.27753237626744 | 0.000432817858966577 | 0.00404176183589148 |
ETS1#2113 | 4 | 5.55929195554419 | 0.00302256447530346 | 0.0160492964175209 |
GABPB1#2553 | 6 | 6.05801471672758 | 4.93271023131083e-05 | 0.000853632682432265 |
GTF2B#2959 | 6 | 27.3804256579922 | 6.39564885927993e-09 | 5.05261097741555e-07 |
GTF2F1#2962 | 6 | 10.9197093229351 | 1.52580683448537e-06 | 5.86722164899918e-05 |
HEY1#23462 | 6 | 3.46295232266204 | 0.00126789009587212 | 0.00850518168943341 |
KAT2A#2648 | 3 | 264.038571428571 | 1.47466334870275e-07 | 8.31151459660908e-06 |
MAX#4149 | 6 | 5.53076186486325 | 8.40673768319711e-05 | 0.00126166299309588 |
MXI1#4601 | 4 | 5.69232664500531 | 0.00276690540539156 | 0.0151612189734359 |
MYC#4609 | 6 | 4.47624160423663 | 0.000288361195091082 | 0.00306369835748906 |
NFKB1#4790 | 6 | 4.70405436359472 | 0.00021611506140197 | 0.00247677393808409 |
NRF1#4899 | 5 | 8.72162817693636 | 6.71450045004423e-05 | 0.00107340534593934 |
POU2F2#5452 | 6 | 7.80524919235073 | 1.11144903558223e-05 | 0.000284576184915844 |
RAD21#5885 | 4 | 5.91716222597504 | 0.00239318493722796 | 0.0135535947974162 |
RDBP#7936 | 3 | 65.8450302814393 | 9.4409612230599e-06 | 0.000250955599179219 |
REST#5978 | 5 | 6.89287765437716 | 0.000209438858484651 | 0.00243852674930641 |
RFX5#5993 | 5 | 8.60565059085364 | 7.16524263203101e-05 | 0.00112734374095614 |
SIN3A#25942 | 6 | 4.63618690869869 | 0.000235167814635783 | 0.00256535318495368 |
SIX5#147912 | 4 | 9.76383734597657 | 0.000355537135106872 | 0.00355874476264391 |
SMC3#9126 | 4 | 8.59710448281877 | 0.000579846628016137 | 0.00486649003402261 |
SP2#6668 | 4 | 14.9448745679112 | 6.81071539656055e-05 | 0.00108778759030645 |
SPI1#6688 | 4 | 4.68818486201299 | 0.00568568052914417 | 0.0256648134495954 |
SRF#6722 | 3 | 5.91307639807192 | 0.0106686813016745 | 0.0393914447594423 |
STAT2#6773 | 2 | 18.6467917675545 | 0.00468275705257902 | 0.0220935337827205 |
TAF1#6872 | 6 | 2.86546824492454 | 0.00372833020747146 | 0.0185854173327341 |
TAF7#6879 | 6 | 9.79977377564907 | 2.89681485118392e-06 | 9.9454453071268e-05 |
TBP#6908 | 6 | 3.17723201751119 | 0.00207411205185266 | 0.0120183193843453 |
TCF12#6938 | 6 | 9.1152556304455 | 4.4461156654571e-06 | 0.000139109608743162 |
YY1#7528 | 6 | 4.20957492844616 | 0.00041168337886575 | 0.00392190097649914 |
ZNF143#7702 | 6 | 11.5721799019096 | 1.08146108094101e-06 | 4.49628637867825e-05 |
ZNF263#10127 | 5 | 5.8727440264362 | 0.000451394263989067 | 0.00419796665509832 |
ZZZ3#26009 | 3 | 102.605662472243 | 2.50907428413451e-06 | 8.831992219775e-05 |
Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data
This analysis result is provided for C0 - C305 clusters.