Coexpression cluster:C55: Difference between revisions
From FANTOM5_SSTAR
No edit summary |
No edit summary |
||
(One intermediate revision by the same user not shown) | |||
Line 1: | Line 1: | ||
{ | |||
Latest revision as of 10:19, 17 September 2013
Full id: C55_hepatocellular_Intestinal_liver_Prostate_fibrosarcoma_Hepatocyte_hepatoblastoma
Phase1 CAGE Peaks
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
p.value | FDR | nGenes | nPathway | Name |
---|---|---|---|---|
8.17881719741253e-05 | 0.0258859564298107 | 3 | 32 | Glycine, serine and threonine metabolism (KEGG):00260 |
8.00199645816997e-05 | 0.0258859564298107 | 5 | 167 | Protein processing in endoplasmic reticulum (KEGG):04141 |
Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0048523 | negative regulation of cellular process | 6.81827261879106e-05 |
GO:0048519 | negative regulation of biological process | 6.81827261879106e-05 |
GO:0005737 | cytoplasm | 0.000185855571169113 |
GO:0032502 | developmental process | 0.000185855571169113 |
GO:0009308 | amine metabolic process | 0.00294254112687248 |
GO:0044424 | intracellular part | 0.00294254112687248 |
GO:0050794 | regulation of cellular process | 0.00334723432556309 |
GO:0006807 | nitrogen compound metabolic process | 0.00334723432556309 |
GO:0005622 | intracellular | 0.00477375089228617 |
GO:0043066 | negative regulation of apoptosis | 0.00477375089228617 |
GO:0043069 | negative regulation of programmed cell death | 0.00477375089228617 |
GO:0005507 | copper ion binding | 0.00477375089228617 |
GO:0065007 | biological regulation | 0.00483481303722764 |
GO:0030203 | glycosaminoglycan metabolic process | 0.00647906985230723 |
GO:0006022 | aminoglycan metabolic process | 0.00647906985230723 |
GO:0005515 | protein binding | 0.00648820666693384 |
GO:0050789 | regulation of biological process | 0.00745643247276909 |
GO:0016740 | transferase activity | 0.00928332280295425 |
GO:0043231 | intracellular membrane-bound organelle | 0.0104405941754571 |
GO:0043227 | membrane-bound organelle | 0.0104405941754571 |
GO:0006916 | anti-apoptosis | 0.0115121948588216 |
GO:0048869 | cellular developmental process | 0.0140875576165585 |
GO:0030154 | cell differentiation | 0.0140875576165585 |
GO:0048468 | cell development | 0.0141484093596958 |
GO:0008207 | C21-steroid hormone metabolic process | 0.0159869972467686 |
GO:0000074 | regulation of progression through cell cycle | 0.0159869972467686 |
GO:0051726 | regulation of cell cycle | 0.0162629714021646 |
GO:0000188 | inactivation of MAPK activity | 0.0162629714021646 |
GO:0009653 | anatomical structure morphogenesis | 0.0181033809190882 |
GO:0007040 | lysosome organization and biogenesis | 0.0188059199735649 |
GO:0007033 | vacuole organization and biogenesis | 0.0217307969928773 |
GO:0045786 | negative regulation of progression through cell cycle | 0.0217307969928773 |
GO:0043229 | intracellular organelle | 0.0224235476719124 |
GO:0043226 | organelle | 0.0224235476719124 |
GO:0006915 | apoptosis | 0.0224235476719124 |
GO:0043407 | negative regulation of MAP kinase activity | 0.0224235476719124 |
GO:0012501 | programmed cell death | 0.0224235476719124 |
GO:0022402 | cell cycle process | 0.0224235476719124 |
GO:0016043 | cellular component organization and biogenesis | 0.0232054936195745 |
GO:0008219 | cell death | 0.0276202546581823 |
GO:0016265 | death | 0.0276202546581823 |
GO:0000287 | magnesium ion binding | 0.0285112543427892 |
GO:0001525 | angiogenesis | 0.0306533952330491 |
GO:0016263 | glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity | 0.0306533952330491 |
GO:0004760 | serine-pyruvate transaminase activity | 0.0306533952330491 |
GO:0046724 | oxalic acid secretion | 0.0306533952330491 |
GO:0060155 | platelet dense granule organization and biogenesis | 0.0306533952330491 |
GO:0042866 | pyruvate biosynthetic process | 0.0306533952330491 |
GO:0016656 | monodehydroascorbate reductase (NADH) activity | 0.0306533952330491 |
GO:0019265 | glycine biosynthetic process, by transamination of glyoxylate | 0.0306533952330491 |
GO:0051657 | maintenance of organelle localization | 0.0306533952330491 |
GO:0008812 | choline dehydrogenase activity | 0.0306533952330491 |
GO:0043691 | reverse cholesterol transport | 0.0306533952330491 |
GO:0051659 | maintenance of mitochondrion localization | 0.0306533952330491 |
GO:0021904 | dorsoventral neural tube patterning | 0.0306533952330491 |
GO:0015677 | copper ion import | 0.0306533952330491 |
GO:0001822 | kidney development | 0.0322183147854345 |
GO:0044464 | cell part | 0.036485895133149 |
GO:0001655 | urogenital system development | 0.036485895133149 |
GO:0048514 | blood vessel morphogenesis | 0.036485895133149 |
GO:0016772 | transferase activity, transferring phosphorus-containing groups | 0.036485895133149 |
GO:0051235 | maintenance of localization | 0.036485895133149 |
GO:0000165 | MAPKKK cascade | 0.036485895133149 |
GO:0048646 | anatomical structure formation | 0.036485895133149 |
GO:0048856 | anatomical structure development | 0.036485895133149 |
GO:0016301 | kinase activity | 0.036485895133149 |
GO:0001568 | blood vessel development | 0.036485895133149 |
GO:0001944 | vasculature development | 0.036485895133149 |
GO:0016773 | phosphotransferase activity, alcohol group as acceptor | 0.036485895133149 |
GO:0032331 | negative regulation of chondrocyte differentiation | 0.036485895133149 |
GO:0006670 | sphingosine metabolic process | 0.036485895133149 |
GO:0033700 | phospholipid efflux | 0.036485895133149 |
GO:0021532 | neural tube patterning | 0.036485895133149 |
GO:0004105 | choline-phosphate cytidylyltransferase activity | 0.036485895133149 |
GO:0033363 | secretory granule organization and biogenesis | 0.036485895133149 |
GO:0055091 | phospholipid homeostasis | 0.036485895133149 |
GO:0008481 | sphinganine kinase activity | 0.036485895133149 |
GO:0030810 | positive regulation of nucleotide biosynthetic process | 0.036485895133149 |
GO:0043072 | negative regulation of non-apoptotic programmed cell death | 0.036485895133149 |
GO:0032387 | negative regulation of intracellular transport | 0.036485895133149 |
GO:0030816 | positive regulation of cAMP metabolic process | 0.036485895133149 |
GO:0045981 | positive regulation of nucleotide metabolic process | 0.036485895133149 |
GO:0004996 | thyroid-stimulating hormone receptor activity | 0.036485895133149 |
GO:0030801 | positive regulation of cyclic nucleotide metabolic process | 0.036485895133149 |
GO:0030349 | syntaxin-13 binding | 0.036485895133149 |
GO:0003943 | N-acetylgalactosamine-4-sulfatase activity | 0.036485895133149 |
GO:0030804 | positive regulation of cyclic nucleotide biosynthetic process | 0.036485895133149 |
GO:0030819 | positive regulation of cAMP biosynthetic process | 0.036485895133149 |
GO:0021978 | telencephalon regionalization | 0.036485895133149 |
GO:0004371 | glycerone kinase activity | 0.036485895133149 |
GO:0042981 | regulation of apoptosis | 0.036485895133149 |
GO:0043067 | regulation of programmed cell death | 0.036485895133149 |
GO:0008289 | lipid binding | 0.036485895133149 |
GO:0007049 | cell cycle | 0.036485895133149 |
GO:0017076 | purine nucleotide binding | 0.036485895133149 |
GO:0009887 | organ morphogenesis | 0.036485895133149 |
GO:0031325 | positive regulation of cellular metabolic process | 0.036485895133149 |
GO:0046983 | protein dimerization activity | 0.036485895133149 |
GO:0044237 | cellular metabolic process | 0.036485895133149 |
GO:0030554 | adenyl nucleotide binding | 0.036485895133149 |
GO:0033043 | regulation of organelle organization and biogenesis | 0.036485895133149 |
GO:0051493 | regulation of cytoskeleton organization and biogenesis | 0.036485895133149 |
GO:0006469 | negative regulation of protein kinase activity | 0.036485895133149 |
GO:0033673 | negative regulation of kinase activity | 0.036485895133149 |
GO:0051348 | negative regulation of transferase activity | 0.036485895133149 |
GO:0005768 | endosome | 0.036485895133149 |
GO:0051496 | positive regulation of stress fiber formation | 0.036485895133149 |
GO:0016151 | nickel ion binding | 0.036485895133149 |
GO:0052185 | modification of structure of other organism during symbiotic interaction | 0.036485895133149 |
GO:0051883 | killing of cells in other organism during symbiotic interaction | 0.036485895133149 |
GO:0004687 | myosin light chain kinase activity | 0.036485895133149 |
GO:0017050 | D-erythro-sphingosine kinase activity | 0.036485895133149 |
GO:0051495 | positive regulation of cytoskeleton organization and biogenesis | 0.036485895133149 |
GO:0052331 | hemolysis by organism of red blood cells in other organism during symbiotic interaction | 0.036485895133149 |
GO:0019836 | hemolysis by symbiont of host red blood cells | 0.036485895133149 |
GO:0045662 | negative regulation of myoblast differentiation | 0.036485895133149 |
GO:0051801 | cytolysis of cells in other organism during symbiotic interaction | 0.036485895133149 |
GO:0004873 | asialoglycoprotein receptor activity | 0.036485895133149 |
GO:0001907 | killing by symbiont of host cells | 0.036485895133149 |
GO:0031640 | killing of cells of another organism | 0.036485895133149 |
GO:0001897 | cytolysis by symbiont of host cells | 0.036485895133149 |
GO:0016244 | non-apoptotic programmed cell death | 0.036485895133149 |
GO:0046487 | glyoxylate metabolic process | 0.036485895133149 |
GO:0051818 | disruption of cells of other organism during symbiotic interaction | 0.036485895133149 |
GO:0008453 | alanine-glyoxylate transaminase activity | 0.036485895133149 |
GO:0044004 | disruption by symbiont of host cells | 0.036485895133149 |
GO:0051817 | modification of morphology or physiology of other organism during symbiotic interaction | 0.036485895133149 |
GO:0051715 | cytolysis of cells of another organism | 0.036485895133149 |
GO:0052332 | modification by organism of cell membrane in other organism during symbiotic interaction | 0.036485895133149 |
GO:0032233 | positive regulation of actin filament bundle formation | 0.036485895133149 |
GO:0043070 | regulation of non-apoptotic programmed cell death | 0.036485895133149 |
GO:0052111 | modification by symbiont of host structure | 0.036485895133149 |
GO:0047756 | chondroitin 4-sulfotransferase activity | 0.036485895133149 |
GO:0045335 | phagocytic vesicle | 0.036485895133149 |
GO:0052025 | modification by symbiont of host cell membrane | 0.036485895133149 |
GO:0052043 | modification by symbiont of host cellular component | 0.036485895133149 |
GO:0044003 | modification by symbiont of host morphology or physiology | 0.036485895133149 |
GO:0052188 | modification of cellular component in other organism during symbiotic interaction | 0.036485895133149 |
GO:0004700 | atypical protein kinase C activity | 0.036485895133149 |
GO:0030501 | positive regulation of bone mineralization | 0.036485895133149 |
GO:0009893 | positive regulation of metabolic process | 0.036485895133149 |
GO:0044421 | extracellular region part | 0.0388616519307626 |
GO:0006629 | lipid metabolic process | 0.0433429772800992 |
GO:0005578 | proteinaceous extracellular matrix | 0.0433429772800992 |
GO:0032366 | intracellular sterol transport | 0.0433429772800992 |
GO:0004682 | protein kinase CK2 activity | 0.0433429772800992 |
GO:0006545 | glycine biosynthetic process | 0.0433429772800992 |
GO:0015643 | toxin binding | 0.0433429772800992 |
GO:0004694 | eukaryotic translation initiation factor 2alpha kinase activity | 0.0433429772800992 |
GO:0046717 | acid secretion | 0.0433429772800992 |
GO:0042448 | progesterone metabolic process | 0.0433429772800992 |
GO:0001542 | ovulation from ovarian follicle | 0.0433429772800992 |
GO:0032365 | intracellular lipid transport | 0.0433429772800992 |
GO:0021871 | forebrain regionalization | 0.0433429772800992 |
GO:0032367 | intracellular cholesterol transport | 0.0433429772800992 |
GO:0032330 | regulation of chondrocyte differentiation | 0.0433429772800992 |
GO:0045987 | positive regulation of smooth muscle contraction | 0.0433429772800992 |
GO:0007500 | mesodermal cell fate determination | 0.0433429772800992 |
GO:0048522 | positive regulation of cellular process | 0.0433964226191836 |
GO:0048037 | cofactor binding | 0.0436614399545067 |
GO:0007275 | multicellular organismal development | 0.0443120627656638 |
GO:0008202 | steroid metabolic process | 0.0448004525197154 |
GO:0016567 | protein ubiquitination | 0.0450379268749544 |
GO:0005604 | basement membrane | 0.0459539309475378 |
GO:0004674 | protein serine/threonine kinase activity | 0.0468111641542894 |
GO:0006066 | alcohol metabolic process | 0.0468111641542894 |
GO:0017016 | Ras GTPase binding | 0.0468111641542894 |
GO:0032446 | protein modification by small protein conjugation | 0.0468111641542894 |
GO:0051646 | mitochondrion localization | 0.0468111641542894 |
GO:0045669 | positive regulation of osteoblast differentiation | 0.0468111641542894 |
GO:0001537 | N-acetylgalactosamine 4-O-sulfotransferase activity | 0.0468111641542894 |
GO:0046521 | sphingoid catabolic process | 0.0468111641542894 |
GO:0030728 | ovulation | 0.0468111641542894 |
GO:0008045 | motor axon guidance | 0.0468111641542894 |
GO:0006656 | phosphatidylcholine biosynthetic process | 0.0468111641542894 |
GO:0048038 | quinone binding | 0.0468111641542894 |
GO:0042787 | protein ubiquitination during ubiquitin-dependent protein catabolic process | 0.0468111641542894 |
GO:0017049 | GTP-Rho binding | 0.0468111641542894 |
GO:0030817 | regulation of cAMP biosynthetic process | 0.0468111641542894 |
GO:0045933 | positive regulation of muscle contraction | 0.0468111641542894 |
GO:0045931 | positive regulation of progression through mitotic cell cycle | 0.0468111641542894 |
GO:0017166 | vinculin binding | 0.0468111641542894 |
GO:0045859 | regulation of protein kinase activity | 0.0468111641542894 |
GO:0032555 | purine ribonucleotide binding | 0.0468815153537965 |
GO:0032553 | ribonucleotide binding | 0.0468815153537965 |
GO:0043549 | regulation of kinase activity | 0.0487375625284291 |
GO:0000151 | ubiquitin ligase complex | 0.0494411935086935 |
GO:0051338 | regulation of transferase activity | 0.0494411935086935 |
GO:0031267 | small GTPase binding | 0.0494411935086935 |
GO:0016323 | basolateral plasma membrane | 0.0494411935086935 |
GO:0005524 | ATP binding | 0.0494411935086935 |
GO:0046688 | response to copper ion | 0.0494411935086935 |
GO:0033344 | cholesterol efflux | 0.0494411935086935 |
GO:0015991 | ATP hydrolysis coupled proton transport | 0.0494411935086935 |
GO:0005956 | protein kinase CK2 complex | 0.0494411935086935 |
GO:0045661 | regulation of myoblast differentiation | 0.0494411935086935 |
GO:0005007 | fibroblast growth factor receptor activity | 0.0494411935086935 |
GO:0030802 | regulation of cyclic nucleotide biosynthetic process | 0.0494411935086935 |
GO:0043682 | copper-transporting ATPase activity | 0.0494411935086935 |
GO:0030808 | regulation of nucleotide biosynthetic process | 0.0494411935086935 |
GO:0051492 | regulation of stress fiber formation | 0.0494411935086935 |
GO:0004008 | copper-exporting ATPase activity | 0.0494411935086935 |
GO:0045778 | positive regulation of ossification | 0.0494411935086935 |
GO:0032231 | regulation of actin filament bundle formation | 0.0494411935086935 |
GO:0030814 | regulation of cAMP metabolic process | 0.0494411935086935 |
GO:0000902 | cell morphogenesis | 0.0494411935086935 |
GO:0032989 | cellular structure morphogenesis | 0.0494411935086935 |
GO:0043086 | negative regulation of catalytic activity | 0.0494411935086935 |
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>
Ontology term | p-value | n |
---|---|---|
metabolising cell | 8.61e-38 | 12 |
endopolyploid cell | 8.61e-38 | 12 |
parenchymal cell | 8.61e-38 | 12 |
polyploid cell | 8.61e-38 | 12 |
hepatocyte | 8.61e-38 | 12 |
endodermal cell | 1.72e-14 | 58 |
intestinal epithelial cell | 1.29e-13 | 4 |
Ontology term | p-value | n |
---|---|---|
liver | 2.73e-24 | 19 |
digestive gland | 2.73e-24 | 19 |
liver bud | 2.73e-24 | 19 |
hepatic diverticulum | 3.99e-21 | 22 |
liver primordium | 3.99e-21 | 22 |
digestive tract diverticulum | 2.97e-20 | 23 |
epithelial sac | 1.02e-18 | 25 |
epithelium of foregut-midgut junction | 1.02e-18 | 25 |
anatomical boundary | 1.02e-18 | 25 |
hepatobiliary system | 1.02e-18 | 25 |
foregut-midgut junction | 1.02e-18 | 25 |
septum transversum | 1.02e-18 | 25 |
sac | 4.90e-18 | 26 |
gut epithelium | 1.70e-15 | 54 |
exocrine gland | 2.73e-15 | 31 |
exocrine system | 2.73e-15 | 31 |
endocrine gland | 1.18e-13 | 35 |
intestinal mucosa | 1.29e-13 | 4 |
wall of intestine | 1.29e-13 | 4 |
gastrointestinal system mucosa | 1.29e-13 | 4 |
gastrointestinal system epithelium | 1.29e-13 | 4 |
intestinal epithelium | 1.29e-13 | 4 |
endocrine system | 7.94e-11 | 45 |
endo-epithelium | 1.66e-10 | 82 |
abdomen element | 3.61e-09 | 54 |
abdominal segment element | 3.61e-09 | 54 |
gland | 1.83e-08 | 59 |
abdominal segment of trunk | 2.45e-08 | 60 |
abdomen | 2.45e-08 | 60 |
subdivision of digestive tract | 1.75e-07 | 118 |
epithelium of mucosa | 1.80e-07 | 8 |
simple columnar epithelium | 8.85e-07 | 9 |
Ontology term | p-value | n |
---|---|---|
disease of anatomical entity | 2.38e-12 | 39 |
Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
---|---|
MA0003.1 | 5.79456e-09 |
MA0004.1 | 0.0773024 |
MA0006.1 | 0.00364569 |
MA0007.1 | 0.307905 |
MA0009.1 | 0.219969 |
MA0014.1 | 2.63594e-10 |
MA0017.1 | 31.8051 |
MA0019.1 | 0.0820964 |
MA0024.1 | 0.0916718 |
MA0025.1 | 1.04535 |
MA0027.1 | 0.945851 |
MA0028.1 | 0.000439089 |
MA0029.1 | 1.4721 |
MA0030.1 | 0.0989656 |
MA0031.1 | 0.276963 |
MA0038.1 | 0.172086 |
MA0040.1 | 0.504739 |
MA0041.1 | 1.90107 |
MA0042.1 | 1.4743 |
MA0043.1 | 0.114583 |
MA0046.1 | 12.7236 |
MA0048.1 | 0.0808186 |
MA0050.1 | 0.134812 |
MA0051.1 | 1.97022 |
MA0052.1 | 0.0571998 |
MA0055.1 | 0.00400339 |
MA0056.1 | 0 |
MA0057.1 | 0.00605178 |
MA0058.1 | 0.0515274 |
MA0059.1 | 0.403534 |
MA0060.1 | 1.59427 |
MA0061.1 | 0.464645 |
MA0063.1 | 0 |
MA0066.1 | 0.342925 |
MA0067.1 | 0.154982 |
MA0068.1 | 0.156424 |
MA0069.1 | 0.335363 |
MA0070.1 | 0.692398 |
MA0071.1 | 0.955425 |
MA0072.1 | 0.0882581 |
MA0073.1 | 0.000339525 |
MA0074.1 | 0.431075 |
MA0076.1 | 2.22509e-05 |
MA0077.1 | 0.647178 |
MA0078.1 | 1.46655 |
MA0081.1 | 0.0500798 |
MA0083.1 | 0.583448 |
MA0084.1 | 0.681902 |
MA0087.1 | 0.90957 |
MA0088.1 | 0.00222108 |
MA0089.1 | 0 |
MA0090.1 | 3.73388 |
MA0091.1 | 0.316121 |
MA0092.1 | 0.315569 |
MA0093.1 | 0.0311995 |
MA0095.1 | 0 |
MA0098.1 | 0 |
MA0100.1 | 0.519975 |
MA0101.1 | 0.289317 |
MA0103.1 | 0.0206402 |
MA0105.1 | 0.000186152 |
MA0106.1 | 1.98315 |
MA0107.1 | 0.525865 |
MA0108.2 | 0.561138 |
MA0109.1 | 0 |
MA0111.1 | 0.739895 |
MA0113.1 | 0.0976176 |
MA0114.1 | 28.5167 |
MA0115.1 | 3.62436 |
MA0116.1 | 0.480351 |
MA0117.1 | 0.0214542 |
MA0119.1 | 0.801893 |
MA0122.1 | 0.330892 |
MA0124.1 | 0.202851 |
MA0125.1 | 0.0083642 |
MA0130.1 | 0 |
MA0131.1 | 0.40361 |
MA0132.1 | 0 |
MA0133.1 | 0 |
MA0135.1 | 0.918826 |
MA0136.1 | 0.0783561 |
MA0139.1 | 0.326951 |
MA0140.1 | 0.933604 |
MA0141.1 | 7.67338 |
MA0142.1 | 0.45415 |
MA0143.1 | 1.15397 |
MA0144.1 | 2.45081 |
MA0145.1 | 0.333015 |
MA0146.1 | 0.302069 |
MA0147.1 | 0.0245253 |
MA0148.1 | 4.34773 |
MA0149.1 | 0.443504 |
MA0062.2 | 0.0010129 |
MA0035.2 | 2.25182 |
MA0039.2 | 2.48573e-05 |
MA0138.2 | 0.05266 |
MA0002.2 | 0.963896 |
MA0137.2 | 0.473174 |
MA0104.2 | 0.00329929 |
MA0047.2 | 5.28977 |
MA0112.2 | 1.54185 |
MA0065.2 | 5.6609 |
MA0150.1 | 0.061649 |
MA0151.1 | 0 |
MA0152.1 | 0.663903 |
MA0153.1 | 6.41566 |
MA0154.1 | 0.966122 |
MA0155.1 | 0.28604 |
MA0156.1 | 0.261369 |
MA0157.1 | 0.363183 |
MA0158.1 | 0 |
MA0159.1 | 1.16594 |
MA0160.1 | 5.45722 |
MA0161.1 | 0 |
MA0162.1 | 5.12936e-10 |
MA0163.1 | 0.0734363 |
MA0164.1 | 1.75384 |
MA0080.2 | 0.271601 |
MA0018.2 | 0.00374053 |
MA0099.2 | 0.157954 |
MA0079.2 | 3.6765e-13 |
MA0102.2 | 0.376414 |
MA0258.1 | 2.91321 |
MA0259.1 | 0.196479 |
MA0442.1 | 0 |
ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data
(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)
TF | #promoters | Enrichment | p-value | q-value |
---|---|---|---|---|
BHLHE40#8553 | 44 | 6.03779754148932 | 2.74165853888483e-21 | 7.36082457950111e-19 |
CEBPB#1051 | 99 | 2.41328322616715 | 2.35453162381174e-17 | 4.89850454699749e-15 |
ELF1#1997 | 100 | 1.30217062960475 | 0.00194303783516052 | 0.011413325560536 |
EP300#2033 | 226 | 4.68168449579952 | 2.71867204467815e-109 | 5.35727150328568e-106 |
ESRRA#2101 | 10 | 14.7963398818387 | 2.37215174195383e-09 | 2.01746869525991e-07 |
FOSL2#2355 | 97 | 5.02210843621555 | 5.09290682880948e-41 | 2.9714977446594e-38 |
FOXA1#3169 | 179 | 6.06597594844036 | 1.25871421917174e-97 | 2.0540445990012e-94 |
FOXA2#3170 | 159 | 11.9762805402868 | 1.37226715457362e-128 | 3.18484909681144e-125 |
HDAC2#3066 | 179 | 7.34371872280153 | 1.75896583135508e-111 | 3.60205161688025e-108 |
HEY1#23462 | 277 | 3.42235706097945 | 1.46709162432103e-115 | 3.06443164304929e-112 |
HNF4A#3172 | 197 | 13.93596697707 | 7.97234088125446e-179 | 2.60194784155417e-175 |
HNF4G#3174 | 201 | 17.6741221034122 | 8.58644119977634e-204 | 3.89895361940627e-200 |
JUND#3727 | 64 | 1.36898621492277 | 0.0053539376216859 | 0.0245957548724929 |
MAFF#23764 | 26 | 4.47767360470512 | 3.47578549461043e-10 | 3.48375778571611e-08 |
MAFK#7975 | 39 | 3.2321975301999 | 1.81442778230609e-10 | 1.88930232458889e-08 |
POLR2A#5430 | 252 | 1.65491804431998 | 1.64835325745213e-29 | 6.49631569264312e-27 |
PPARGC1A#10891 | 5 | 5.3524638587712 | 0.00265894226173134 | 0.0146727925009489 |
RXRA#6256 | 155 | 9.51549130448213 | 5.13663912805526e-110 | 1.03166433441339e-106 |
SIN3A#25942 | 94 | 1.55484759731077 | 4.11211014306236e-06 | 0.000130576063007385 |
SP1#6667 | 216 | 3.76406843326738 | 8.98779606515958e-84 | 1.15885979413482e-80 |
SREBF1#6720 | 25 | 3.59371937618412 | 5.58328289654898e-08 | 3.5000749245659e-06 |
SREBF2#6721 | 5 | 6.68108963931724 | 0.00101435548472493 | 0.00719640462395131 |
SRF#6722 | 46 | 1.94088746195633 | 1.35079318783528e-05 | 0.000327473281672074 |
TAF1#6872 | 123 | 1.2574761258308 | 0.00169880088848513 | 0.0106138469725113 |
TBP#6908 | 202 | 2.28980941527055 | 1.40749483729893e-39 | 8.03264225752254e-37 |
TCF12#6938 | 50 | 1.62606496975328 | 0.000450535368441019 | 0.00419035206559903 |
TCF7L2#6934 | 182 | 5.99441019722017 | 7.72946104802088e-99 | 1.281360606975e-95 |
USF1#7391 | 69 | 1.34233470986957 | 0.0059707514692238 | 0.0267757015197847 |
Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data