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MCL coexpression mm9:1626: Difference between revisions

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{{MCL_coexpression_mm9
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symporter activity;0.0149564455158056;54403!GO:0015701;bicarbonate transport;0.0256241713817642;54403!GO:0005452;inorganic anion exchanger activity;0.0256241713817642;54403!GO:0015380;anion exchanger activity;0.0256241713817642;54403!GO:0015106;bicarbonate transmembrane transporter activity;0.0256241713817642;54403!GO:0015301;anion:anion antiporter activity;0.0256241713817642;54403!GO:0015108;chloride transmembrane transporter activity;0.0256241713817642;54403!GO:0015296;anion:cation symporter activity;0.0283892302834395;54403!GO:0006885;regulation of pH;0.0283892302834395;54403!GO:0015071;protein phosphatase type 2C activity;0.0283892302834395;19042!GO:0008287;protein serine/threonine phosphatase complex;0.0285219372589867;19042!GO:0015103;inorganic anion transmembrane transporter activity;0.0336041502350863;54403!GO:0004722;protein serine/threonine phosphatase activity;0.0336041502350863;19042!GO:0043169;cation binding;0.0336041502350863;54403,19042,223455!GO:0015297;antiporter activity;0.0376142207968676;54403!GO:0046872;metal ion binding;0.0376142207968676;54403,19042,223455!GO:0043167;ion binding;0.0376485239032373;54403,19042,223455!GO:0015294;solute:cation symporter 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|gostat_on_MCL_coexpression=GO:0008510;sodium:bicarbonate symporter activity;0.0149564455158056;54403!GO:0015701;bicarbonate transport;0.0256241713817642;54403!GO:0005452;inorganic anion exchanger activity;0.0256241713817642;54403!GO:0015380;anion exchanger activity;0.0256241713817642;54403!GO:0015106;bicarbonate transmembrane transporter activity;0.0256241713817642;54403!GO:0015301;anion:anion antiporter activity;0.0256241713817642;54403!GO:0015108;chloride transmembrane transporter activity;0.0256241713817642;54403!GO:0015296;anion:cation symporter activity;0.0283892302834395;54403!GO:0006885;regulation of pH;0.0283892302834395;54403!GO:0015071;protein phosphatase type 2C activity;0.0283892302834395;19042!GO:0008287;protein serine/threonine phosphatase complex;0.0285219372589867;19042!GO:0015103;inorganic anion transmembrane transporter activity;0.0336041502350863;54403!GO:0004722;protein serine/threonine phosphatase activity;0.0336041502350863;19042!GO:0043169;cation binding;0.0336041502350863;54403,19042,223455!GO:0015297;antiporter activity;0.0376142207968676;54403!GO:0046872;metal ion binding;0.0376142207968676;54403,19042,223455!GO:0043167;ion binding;0.0376485239032373;54403,19042,223455!GO:0015294;solute:cation symporter activity;0.0430868884768256;54403!
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|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0004111!1.56e-09!122;UBERON:0000073!1.71e-09!54;UBERON:0000025!3.34e-09!114;UBERON:0001049!2.42e-08!52;UBERON:0005068!2.42e-08!52;UBERON:0006241!2.42e-08!52;UBERON:0007135!2.42e-08!52;UBERON:0000481!2.75e-08!230;UBERON:0002020!1.35e-07!34;UBERON:0002021!5.40e-07!10;UBERON:0000411!5.40e-07!10;UBERON:0001950!5.40e-07!10
|tfbs_overrepresentation_for_novel_motifs=0.557864,1.52338,0.529553,0.603273,0.406364,0.618805,0.715644,0.300268,0.310789,1.22306,0.668936,0.702872,0.300533,0.728641,0.424775,0,2.14511,0.397593,0.283802,0.545768,0.489529,0.44579,0.727684,0.404661,1.32977,0.757752,0.274609,0.641282,0.456327,0.227599,0.626183,1.03545,0.395107,0.253145,0.425309,0.454919,4.70122,0.699032,0.360612,0.328675,0.401916,0.631725,0.134724,0.426986,1.28479,0.591277,0.847828,0.658142,0.115788,0.459555,0.912738,1.84811,0.220111,1.18062,1.19842,0.73621,0.469329,0.689304,0.26467,0.734051,1.01481,1.86856,0.323911,0.901018,0.747985,0.943088,1.33705,1.68977,1.00999,1.54147,0.509047,0.30684,7.13762,1.23259,2.03319,1.96909,0.253065,0.835925,0.997094,0.494135,0.308173,0.948899,0.794502,0.293164,1.1148,1.99513,0.297068,0.227755,1.9856,1.85284,1.40768,1.11989,1.04863,0.412897,1.67286,0.3366,0.297538,1.05152,0.848095,0.20438,0.384901,1.03517,1.16282,0.913356,0.91226,1.52669,0.97421,0.653843,2.15911,1.23125,0.550229,1.16464,1.23956,0.674448,1.41481,0.399936,2.24107,1.47653,0.932233,0.380707,1.23809,0.879184,0.759676,0.834976,1.46955,1.00091,0.724289,1.04166,1.33551,0.416189,1.14546,0.595426,1.3055,0.750642,1.43666,0.143464,0.566955,0.633235,1.3869,2.2222,1.82084,1.34183,0.772375,1.04623,0.905521,0.632211,0.851091,2.18247,0.569503,0.408309,0.651755,7.7345,1.18223,0.908552,0.749664,1.26545,0.787153,0.438007,0.555203,0.566652,1.39653,1.11392,1.00137,0.547782,0.90208,0.741834,0.383572,0.701187,1.60845
}}

Latest revision as of 17:14, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr12:73862204..73862252,+p2@Ppm1a
Mm9::chr12:73862254..73862303,+p1@Ppm1a
Mm9::chr15:31460754..31460824,-p1@March6
Mm9::chr16:13671951..13672011,+p2@3110001I22Rik
p2@Bfar
Mm9::chr5:89315834..89315850,+p1@Slc4a4


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0008510sodium:bicarbonate symporter activity0.0149564455158056
GO:0015701bicarbonate transport0.0256241713817642
GO:0005452inorganic anion exchanger activity0.0256241713817642
GO:0015380anion exchanger activity0.0256241713817642
GO:0015106bicarbonate transmembrane transporter activity0.0256241713817642
GO:0015301anion:anion antiporter activity0.0256241713817642
GO:0015108chloride transmembrane transporter activity0.0256241713817642
GO:0015296anion:cation symporter activity0.0283892302834395
GO:0006885regulation of pH0.0283892302834395
GO:0015071protein phosphatase type 2C activity0.0283892302834395
GO:0008287protein serine/threonine phosphatase complex0.0285219372589867
GO:0015103inorganic anion transmembrane transporter activity0.0336041502350863
GO:0004722protein serine/threonine phosphatase activity0.0336041502350863
GO:0043169cation binding0.0336041502350863
GO:0015297antiporter activity0.0376142207968676
GO:0046872metal ion binding0.0376142207968676
GO:0043167ion binding0.0376485239032373
GO:0015294solute:cation symporter activity0.0430868884768256



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
anatomical conduit1.56e-09122
regional part of nervous system1.71e-0954
tube3.34e-09114
neural tube2.42e-0852
neural rod2.42e-0852
future spinal cord2.42e-0852
neural keel2.42e-0852
multi-tissue structure2.75e-08230
gray matter1.35e-0734
occipital lobe5.40e-0710
visual cortex5.40e-0710
neocortex5.40e-0710


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.12.77888
MA0004.10.603793
MA0006.11.07705
MA0007.11.43525
MA0009.11.06266
MA0014.16.99888
MA0017.10.449113
MA0019.10.874061
MA0024.11.01759
MA0025.11.30092
MA0027.12.72141
MA0028.10.43138
MA0029.10.995171
MA0030.11.00195
MA0031.10.965177
MA0038.10.757669
MA0040.11.07552
MA0041.10.522007
MA0042.10.507715
MA0043.11.1618
MA0046.11.09955
MA0048.11.7574
MA0050.10.645342
MA0051.10.767098
MA0052.11.08379
MA0055.10.602741
MA0056.10
MA0057.12.39011
MA0058.10.50032
MA0059.10.513699
MA0060.10.330907
MA0061.10.364227
MA0063.10
MA0066.10.746072
MA0067.11.41352
MA0068.10.197245
MA0069.11.08414
MA0070.11.07418
MA0071.10.644448
MA0072.11.06547
MA0073.10.65603
MA0074.10.708108
MA0076.11.1853
MA0077.11.04318
MA0078.10.801834
MA0081.10.53877
MA0083.11.16099
MA0084.11.74401
MA0087.11.11687
MA0088.10.148348
MA0089.10
MA0090.10.566938
MA0091.10.617887
MA0092.10.567278
MA0093.10.440484
MA0095.10
MA0098.10
MA0100.10.695835
MA0101.10.523409
MA0103.10.460936
MA0105.10.248108
MA0106.10.809991
MA0107.10.454197
MA0108.20.897859
MA0109.10
MA0111.10.582193
MA0113.10.780358
MA0114.10.361633
MA0115.11.16466
MA0116.10.419688
MA0117.11.13165
MA0119.10.524046
MA0122.11.15196
MA0124.11.35963
MA0125.11.28445
MA0130.10
MA0131.10.869325
MA0132.10
MA0133.10
MA0135.11.19898
MA0136.10.729175
MA0139.10.295945
MA0140.10.695713
MA0141.10.482463
MA0142.10.950155
MA0143.10.797553
MA0144.10.365053
MA0145.10.927481
MA0146.10.822925
MA0147.10.986917
MA0148.10.621195
MA0149.10.529387
MA0062.20.706751
MA0035.20.700704
MA0039.26.31018
MA0138.20.861035
MA0002.20.299191
MA0137.20.479301
MA0104.21.52809
MA0047.20.75686
MA0112.20.157681
MA0065.20.929207
MA0150.10.587557
MA0151.10
MA0152.10.756973
MA0153.11.21594
MA0154.10.587595
MA0155.10.515751
MA0156.10.469089
MA0157.10.91689
MA0158.10
MA0159.10.389847
MA0160.10.624415
MA0161.10
MA0162.16.08017
MA0163.12.36557
MA0164.10.729558
MA0080.20.455167
MA0018.21.75252
MA0099.20.854449
MA0079.210.8444
MA0102.21.79669
MA0258.10.346619
MA0259.10.960816
MA0442.10
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