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(Created page with "{{f5samples |id=FF:10041-101F5 |name=dura mater, adult, donor1 |sample_id=10041 |rna_tube_id=101F5 |rna_box=101 |rna_position=F5 |sample_cell_lot=NA |sample_cell_catal...")
 
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{{f5samples
{{f5samples
|id=FF:10041-101F5
|DRA_sample_Accession=CAGE@SAMD00005192
|name=dura mater, adult, donor1
|accession_numbers=CAGE;DRX008647;DRR009519;DRZ000944;DRZ002329;DRZ012294;DRZ013679
|sample_id=10041
|ancestors_in_anatomy_facet=UBERON:0000468,UBERON:0007023,UBERON:0002363,UBERON:0002360,UBERON:0000479,UBERON:0004121,UBERON:0010314,UBERON:0011216,UBERON:0000062,UBERON:0004120,UBERON:0000061,UBERON:0000465,UBERON:0000477,UBERON:0000467,UBERON:0001062,UBERON:0000480,UBERON:0000094,UBERON:0010317,UBERON:0001017,UBERON:0001016,UBERON:0010743
|rna_tube_id=101F5
|rna_box=101
|rna_position=F5
|sample_cell_lot=NA
|sample_cell_catalog=NA
|sample_company=Clontech
|rna_lot_number=3040808.00000
|rna_catalog_number=Cat:636588
|sample_species=Human (Homo sapiens)
|sample_strain=
|sample_dev_stage=59 years old adult
|sample_tissue=dura mater
|sample_donor(cell lot)=1.00000
|sample_sex=female
|sample_age=
|sample_ethnicity=C
|rna_rin=
|rna_od260/230=
|rna_od260/280=
|sample_cell_type=CELL MIXTURE - tissue sample
|sample_cell_line=
|sample_collaboration=FANTOM5 OSC CORE (contact: Al Forrest)
|sample_experimental_condition=
|sample_disease=normal
|rna_sample_type=total RNA
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-TRIzol-isopropanol-v1.0
|rna_weight_ug=50.00000
|rna_concentration=
|sample_note=
|profile_hcage=CNhs10648,LSID658,release008,COMPLETED
|profile_cagescan=,,,
|profile_srnaseq=,,,
|profile_rnaseq=,,,
|ancestors_in_cell_lineage_facet=
|ancestors_in_cell_lineage_facet=
|ancestors_in_anatomy_facet=UBERON:0000061,UBERON:0000062,UBERON:0000073,UBERON:0000094,UBERON:0000465,UBERON:0000467,UBERON:0000468,UBERON:0000479,UBERON:0000480,UBERON:0000922,UBERON:0000923,UBERON:0000924,UBERON:0000926,UBERON:0001016,UBERON:0001017,UBERON:0001062,UBERON:0002050,UBERON:0002342,UBERON:0002346,UBERON:0002360,UBERON:0002363,UBERON:0002532,UBERON:0003075,UBERON:0004120,UBERON:0004121,UBERON:0005423,UBERON:0005743,UBERON:0006598,UBERON:0007023,UBERON:0007284,UBERON:0007645,UBERON:0007647
|ancestors_in_disease_facet=
|ancestors_in_disease_facet=
|sample_description=
|ancestors_in_ff_facet=FF:0000102,FF:0000210,FF:0000101,FF:0000001,FF:0000998,FF:0000004,FF:0010041
 
|comment=
|created_by=
|creation_date=
|data_phase=2
|datafreeze_phase=2
|def=
|expression_enrichment_score=chr2:68592406..68592424,+!p1@PLEK!2.04!108.05!PLEK;;chr11:47400078..47400106,-!p1@SPI1!2.03!105.84!SPI1;;chr1:170632285..170632309,+!p1@PRRX1!1.96!102.49!PRRX1;;chr16:85932760..85932775,+!p1@IRF8!1.74!54.34!IRF8;;chr21:39870339..39870443,-!p1@ERG!1.71!50.42!ERG;;chr2:45236540..45236577,-!p1@SIX2!1.65!43.60!SIX2;;chr20:39317868..39317884,-!p1@MAFB!1.64!480.91!MAFB;;chr11:113930425..113930471,+!p1@ZBTB16!1.64!60.09!ZBTB16;;chr3:147127142..147127168,+!p1@ZIC1!1.63!41.20!ZIC1;;chr17:53344945..53344977,+!p2@HLF!1.62!40.94!HLF;;chr1:40105299..40105326,-!p1@HEYL!1.58!37.15!HEYL;;chr13:100634031..100634045,+!p1@ZIC2!1.58!37.03!ZIC2;;chr1:170633348..170633399,+!p2@PRRX1!1.57!48.53!PRRX1;;chr11:47399947..47399961,-!p3@SPI1!1.55!34.44!SPI1;;chr11:47400062..47400077,-!p2@SPI1!1.55!34.37!SPI1;;chr17:38256799..38256815,-!p3@NR1D1!1.52!57.50!NR1D1;;chr14:61116183..61116208,-!p1@SIX1!1.51!114.81!SIX1;;chr20:62680984..62680999,-!p1@SOX18!1.51!41.45!SOX18;;chr1:170632477..170632506,+!p6@PRRX1!1.51!31.53!PRRX1;;chr3:147127177..147127194,+!p2@ZIC1!1.51!31.40!ZIC1;;chr17:53342311..53342400,+!p1@HLF!1.50!34.88!HLF;;chr3:71630980..71631110,-!p3@FOXP1!1.48!98.89!FOXP1;;chr17:53344980..53345011,+!p3@HLF!1.48!29.26!HLF;;chr6:1610293..1610310,+!p1@FOXC1!1.45!44.67!FOXC1;;chrX:2418949..2419024,-!p1@DHRSX,p1@ZBED1!1.44!26.79!ZBED1;;chr12:26277817..26277863,-!p2@BHLHE41!1.43!34.75!BHLHE41;;chr5:88178983..88179012,-!p1@MEF2C!1.42!187.35!MEF2C;;chr12:54778471..54778528,-!p1@ZNF385A!1.41!24.71!ZNF385A;;chr1:47903709..47903764,+!p1@BC169308!1.38!25.91!FOXD2;;chr16:86600426..86600441,+!p1@FOXC2!1.34!50.36!FOXC2;;chr1:170633262..170633285,+!p3@PRRX1!1.33!23.38!PRRX1;;chr19:46801639..46801699,+!p1@HIF3A!1.32!19.97!HIF3A;;chr11:44331576..44331650,-!p1@ALX4!1.32!19.78!ALX4;;chr5:122424955..122424988,+!p2@PRDM6!1.31!19.65!PRDM6;;chr2:145277640..145277771,-!p1@ZEB2!1.30!248.20!ZEB2;;chr1:170632683..170632696,+!p12@PRRX1!1.29!18.70!PRRX1;;chr9:132427972..132428056,+!p1@PRRX2!1.28!23.51!PRRX2;;chr6:45296048..45296082,+!p1@RUNX2!1.28!20.60!RUNX2;;chr1:170632115..170632136,+!p9@PRRX1!1.28!18.20!PRRX1;;chr7:96654133..96654150,-!p1@DLX5!1.28!18.13!DLX5;;chr5:122424918..122424944,+!p1@PRDM6!1.28!18.07!PRDM6;;chr7:44143925..44143970,+!p1@AEBP1!1.26!370.91!AEBP1;;chr1:170632723..170632739,+!p8@PRRX1!1.26!17.19!PRRX1;;chr4:26165074..26165110,+!p9@RBPJ!1.26!17.19!RBPJ;;chr1:170632137..170632172,+!p10@PRRX1!1.25!16.87!PRRX1;;chr5:158526917..158526932,-!p1@EBF1!1.22!38.16!EBF1;;chr1:170632959..170632987,+!p4@PRRX1!1.22!16.93!PRRX1;;chr17:38256822..38256851,-!p1@NR1D1!1.21!116.71!NR1D1;;chr4:4861385..4861398,+!p1@MSX1!1.21!44.93!MSX1;;chr7:115670804..115670825,-!p1@TFEC!1.20!14.72!TFEC;;chr7:113726357..113726443,+!p1@FOXP2!1.19!25.15!FOXP2;;chr11:47399996..47400014,-!p4@SPI1!1.19!14.66!SPI1;;chr7:63505799..63505904,+!p1@ZNF727!1.19!14.60!ZNF727;;chr1:119530706..119530736,-!p3@TBX15!1.18!14.09!TBX15;;chr1:170632439..170632465,+!p11@PRRX1!1.18!14.03!PRRX1;;chr11:113930291..113930339,+!p2@ZBTB16!1.17!22.24!ZBTB16;;chr6:19837592..19837621,+!p1@ID4!1.16!81.07!ID4;;chrX:106960180..106960197,-!p2@TSC22D3!1.15!50.30!TSC22D3;;chr7:44143978..44143989,+!p2@AEBP1!1.15!24.07!AEBP1;;chr11:47400032..47400043,-!p5@SPI1!1.15!13.08!SPI1;;chr11:125034640..125034655,+!p1@PKNOX2!1.14!12.70!PKNOX2;;chr19:45971246..45971265,+!p1@FOSB!1.12!224.69!FOSB;;chr19:13134772..13134822,+!p2@NFIX!1.11!17.69!NFIX;;chr1:119530493..119530572,-!p1@TBX15!1.11!12.01!TBX15;;chr7:50344289..50344323,+!p1@IKZF1!1.11!11.75!IKZF1;;chr12:26277956..26277980,-!p1@BHLHE41!1.10!42.02!BHLHE41;;chr7:137620684..137620711,-!p4@CREB3L2!1.10!11.50!CREB3L2;;chr5:92918919..92918942,+!p1@NR2F1!1.09!51.05!NR2F1;;chr6:391743..391759,+!p1@IRF4!1.09!11.44!IRF4;;chr11:44331679..44331702,-!p2@ALX4!1.09!11.44!ALX4;;chr11:113930401..113930422,+!p3@ZBTB16!1.07!10.80!ZBTB16;;chr19:16435625..16435682,+!p1@KLF2!1.06!338.62!KLF2;;chr1:61548374..61548415,+!p4@NFIA!1.06!19.84!NFIA;;chr9:132427883..132427951,+!p2@PRRX2!1.06!10.55!PRRX2;;chr11:111249993..111250006,-!p1@POU2AF1!1.06!10.49!POU2AF1;;chr11:47400045..47400060,-!p6@SPI1!1.06!10.43!SPI1;;chr9:73028814..73028895,-!p1@KLF9!1.05!103.12!KLF9;;chrX:106960285..106960299,-!p1@TSC22D3!1.04!273.35!TSC22D3;;chr9:114287433..114287513,+!p1@ZNF483!1.04!26.10!ZNF483;;chr7:44143997..44144008,+!p3@AEBP1!1.04!12.83!AEBP1;;chr7:15726243..15726293,-!p2@MEOX2!1.04!9.98!MEOX2;;chr9:110252035..110252057,-!p1@KLF4!1.03!155.88!KLF4;;chr12:11802753..11802834,+!p2@ETV6!1.03!47.83!ETV6;;chr16:79633894..79633954,-!p3@MAF!1.03!19.02!MAF;;chr8:55370487..55370503,+!p1@SOX17!1.03!9.73!SOX17;;chr18:42260920..42260951,+!p4@SETBP1!1.03!9.67!SETBP1;;chr16:79634624..79634642,-!p1@MAF!1.02!38.04!MAF;;chr18:42260840..42260860,+!p2@SETBP1!1.02!9.41!SETBP1;;chr2:145277882..145277967,-!p3@ZEB2!1.01!16.24!ZEB2;;chr5:158526459..158526481,-!p2@EBF1!1.01!12.26!EBF1;;chr20:50179368..50179392,-!p2@NFATC2!1.01!12.13!NFATC2;;chr6:126240442..126240459,+!p4@NCOA7!1.01!11.75!NCOA7;;chr1:170632250..17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|fantom_cat=http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0001016;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0010743
|ffid_belonging_in_development=UBERON:0002532,UBERON:0006601,UBERON:0006603,UBERON:0010115,UBERON:0010316
|fonse_cell_line=
|fonse_cell_line=
|fonse_cell_line_closure=
|fonse_cell_line_closure=
Line 67: Line 41:
|fonse_treatment=
|fonse_treatment=
|fonse_treatment_closure=
|fonse_treatment_closure=
|has_quality=
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.tissue.hCAGE/dura%2520mater%252c%2520adult%252c%2520donor1.CNhs10648.10041-101F5.hg19.nobarcode.bam
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.tissue.hCAGE/dura%2520mater%252c%2520adult%252c%2520donor1.CNhs10648.10041-101F5.hg19.ctss.bed.gz
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.tissue.hCAGE/dura%2520mater%252c%2520adult%252c%2520donor1.CNhs10648.10041-101F5.hg19.nobarcode.rdna.fa.gz
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.tissue.hCAGE/dura%2520mater%252c%2520adult%252c%2520donor1.CNhs10648.10041-101F5.hg38.nobarcode.bam
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.tissue.hCAGE/dura%2520mater%252c%2520adult%252c%2520donor1.CNhs10648.10041-101F5.hg38.nobarcode.ctss.bed.gz
|id=FF:10041-101F5
|is_a=EFO:0002091;;FF:0010041
|is_obsolete=
|library_id=CNhs10648
|library_id_phase_based=2:CNhs10648
|microRNAs=
|microRNAs_nn=
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10041
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10041
|name=dura mater, adult, donor1
|namespace=FANTOM5
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|profile_hcage=CNhs10648,LSID658,release008,COMPLETED
|profile_rnaseq=
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|rna_box=101
|rna_catalog_number=Cat:636588
|rna_concentration=1
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-TRIzol-isopropanol-v1.0
|rna_lot_number=3040808
|rna_od260/230=
|rna_od260/280=
|rna_position=F5
|rna_rin=
|rna_sample_type=total RNA
|rna_tube_id=101F5
|rna_weight_ug=50
|sample_age=
|sample_category=tissues
|sample_cell_catalog=NA
|sample_cell_line=
|sample_cell_lot=NA
|sample_cell_type=CELL MIXTURE - tissue sample
|sample_collaboration=FANTOM5 OSC CORE (contact: Al Forrest)
|sample_company=Clontech
|sample_description=
|sample_dev_stage=59 years old adult
|sample_disease=normal
|sample_donor(cell lot)=1
|sample_ethnicity=C
|sample_experimental_condition=
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;1.48995056993039e-256!GO:0005737;cytoplasm;1.31102669814177e-150!GO:0043226;organelle;2.51902781083901e-112!GO:0043229;intracellular organelle;6.34638135132831e-112!GO:0005515;protein binding;2.33449575978051e-110!GO:0043227;membrane-bound organelle;1.16505354473329e-108!GO:0043231;intracellular membrane-bound organelle;1.76662176284009e-108!GO:0044444;cytoplasmic part;2.82671779703874e-88!GO:0044422;organelle part;1.60988807978377e-70!GO:0044446;intracellular organelle part;5.42654619293159e-69!GO:0032991;macromolecular complex;6.5993555763359e-61!GO:0016043;cellular component organization and biogenesis;4.27772823271828e-55!GO:0043170;macromolecule metabolic process;2.2260012861963e-45!GO:0044238;primary metabolic process;4.86458399320205e-44!GO:0003723;RNA binding;5.65351588653354e-44!GO:0030529;ribonucleoprotein complex;1.78533140824136e-41!GO:0044237;cellular metabolic process;5.57103639624795e-41!GO:0044428;nuclear part;1.25734199729307e-40!GO:0005634;nucleus;1.77788334213944e-40!GO:0033036;macromolecule localization;1.66047954874988e-39!GO:0015031;protein transport;2.04555388614682e-38!GO:0043233;organelle lumen;3.24900222770695e-38!GO:0031974;membrane-enclosed lumen;3.24900222770695e-38!GO:0019538;protein metabolic process;3.78494054964753e-38!GO:0045184;establishment of protein localization;2.16227564559298e-37!GO:0008104;protein localization;1.2761109454095e-36!GO:0043234;protein complex;4.69692015609352e-34!GO:0044260;cellular macromolecule metabolic process;1.68468551948898e-32!GO:0046907;intracellular transport;1.18969920249462e-31!GO:0044267;cellular protein metabolic process;1.6833948434626e-31!GO:0031090;organelle membrane;6.76468707847059e-30!GO:0005829;cytosol;2.37834854527828e-28!GO:0065003;macromolecular complex assembly;7.49149598590578e-27!GO:0006886;intracellular protein transport;1.08409834951268e-26!GO:0016071;mRNA metabolic process;1.19443475524477e-26!GO:0031981;nuclear lumen;1.17346692284221e-25!GO:0051649;establishment of cellular localization;1.5370437325081e-25!GO:0051641;cellular localization;2.76821716301238e-25!GO:0022607;cellular component assembly;1.15913861314216e-24!GO:0043283;biopolymer metabolic process;3.42150736565378e-24!GO:0008380;RNA splicing;3.95102665701894e-24!GO:0006396;RNA processing;6.16140004277777e-24!GO:0006996;organelle organization and biogenesis;3.17965650752806e-23!GO:0006412;translation;3.19998922381045e-23!GO:0016192;vesicle-mediated transport;7.44064069515078e-23!GO:0005739;mitochondrion;1.57117388401543e-22!GO:0006397;mRNA processing;6.49564448845033e-22!GO:0005840;ribosome;3.75503037313511e-21!GO:0031967;organelle envelope;3.20216454303111e-20!GO:0031975;envelope;4.1125718800737e-20!GO:0008134;transcription factor binding;7.36045222182225e-20!GO:0010467;gene expression;1.25196087310214e-18!GO:0003735;structural constituent of ribosome;1.42971399119131e-18!GO:0048770;pigment granule;5.50015571729454e-18!GO:0042470;melanosome;5.50015571729454e-18!GO:0005681;spliceosome;1.51525257397556e-17!GO:0033279;ribosomal subunit;1.97833504042189e-17!GO:0005654;nucleoplasm;2.7741657031661e-17!GO:0044429;mitochondrial part;4.38173997822118e-17!GO:0009059;macromolecule biosynthetic process;1.4663090957776e-16!GO:0005830;cytosolic ribosome (sensu Eukaryota);3.75685216311615e-16!GO:0005794;Golgi apparatus;4.22970183118831e-16!GO:0043228;non-membrane-bound organelle;5.22097318366717e-16!GO:0043232;intracellular non-membrane-bound organelle;5.22097318366717e-16!GO:0000166;nucleotide binding;1.35544256237028e-15!GO:0048523;negative regulation of cellular process;2.32556755885534e-15!GO:0044445;cytosolic part;5.10043789715165e-15!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;5.8680457392988e-15!GO:0005783;endoplasmic reticulum;9.37592015310428e-15!GO:0012501;programmed cell death;1.50818860264191e-14!GO:0044451;nucleoplasm part;1.91862352988578e-14!GO:0051603;proteolysis involved in cellular protein catabolic process;2.78424878670373e-14!GO:0006915;apoptosis;3.01053737206991e-14!GO:0008219;cell death;3.68417273250456e-14!GO:0016265;death;3.68417273250456e-14!GO:0006511;ubiquitin-dependent protein catabolic process;3.89084889983295e-14!GO:0019941;modification-dependent protein catabolic process;4.16618172041738e-14!GO:0043632;modification-dependent macromolecule catabolic process;4.16618172041738e-14!GO:0044265;cellular macromolecule catabolic process;4.32482297930528e-14!GO:0044257;cellular protein catabolic process;8.28202054458463e-14!GO:0030036;actin cytoskeleton organization and biogenesis;1.00510026158319e-13!GO:0044249;cellular biosynthetic process;1.1922579494766e-13!GO:0043285;biopolymer catabolic process;1.2530650510714e-13!GO:0048519;negative regulation of biological process;1.50992020442385e-13!GO:0009058;biosynthetic process;2.23305058346171e-13!GO:0006119;oxidative phosphorylation;5.60684546792431e-13!GO:0050794;regulation of cellular process;6.29258606214434e-13!GO:0006605;protein targeting;7.15776932946607e-13!GO:0022613;ribonucleoprotein complex biogenesis and assembly;7.32924040268546e-13!GO:0005740;mitochondrial envelope;7.63765399457229e-13!GO:0043412;biopolymer modification;8.65437894092593e-13!GO:0031966;mitochondrial membrane;9.77264514945324e-13!GO:0043687;post-translational protein modification;1.08880099796938e-12!GO:0006512;ubiquitin cycle;1.43146053104593e-12!GO:0012505;endomembrane system;1.67406179692931e-12!GO:0000502;proteasome complex (sensu Eukaryota);2.38596230622156e-12!GO:0050789;regulation of biological process;2.70754637083257e-12!GO:0019866;organelle inner membrane;2.70754637083257e-12!GO:0030029;actin filament-based process;2.9629882154655e-12!GO:0006464;protein modification process;4.90798865392989e-12!GO:0030163;protein catabolic process;5.42550254322291e-12!GO:0003712;transcription cofactor activity;9.01678490199797e-12!GO:0006366;transcription from RNA polymerase II promoter;9.69684085986282e-12!GO:0006461;protein complex assembly;1.01322868877073e-11!GO:0006913;nucleocytoplasmic transport;1.03592256030133e-11!GO:0016462;pyrophosphatase activity;1.16168999835068e-11!GO:0048193;Golgi vesicle transport;1.18828955902778e-11!GO:0017111;nucleoside-triphosphatase activity;1.4709996454177e-11!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;1.60031494954933e-11!GO:0016817;hydrolase activity, acting on acid anhydrides;2.24455951255188e-11!GO:0051169;nuclear transport;2.32662721570664e-11!GO:0009057;macromolecule catabolic process;3.57304401161596e-11!GO:0031982;vesicle;4.34535199551232e-11!GO:0032553;ribonucleotide binding;5.29231591531748e-11!GO:0032555;purine ribonucleotide binding;5.29231591531748e-11!GO:0005743;mitochondrial inner membrane;5.56956383989348e-11!GO:0022618;protein-RNA complex assembly;7.3991975584641e-11!GO:0016604;nuclear body;9.00219515586874e-11!GO:0017076;purine nucleotide binding;1.03154916823311e-10!GO:0031988;membrane-bound vesicle;1.25527133437313e-10!GO:0031410;cytoplasmic vesicle;1.80469637776866e-10!GO:0006259;DNA metabolic process;2.35747618794366e-10!GO:0016874;ligase activity;2.53886953051735e-10!GO:0031252;leading edge;2.53886953051735e-10!GO:0016023;cytoplasmic membrane-bound vesicle;3.6638251829385e-10!GO:0008092;cytoskeletal protein binding;4.98756662913509e-10!GO:0016044;membrane organization and biogenesis;6.2481637483556e-10!GO:0005768;endosome;6.59963462940854e-10!GO:0005773;vacuole;1.02029283784491e-09!GO:0016564;transcription repressor activity;1.06731942932487e-09!GO:0006457;protein folding;1.16947574844198e-09!GO:0005793;ER-Golgi intermediate compartment;1.31774859890559e-09!GO:0016607;nuclear speck;1.36111294513555e-09!GO:0006793;phosphorus metabolic process;1.86332564508835e-09!GO:0006796;phosphate metabolic process;1.86332564508835e-09!GO:0015935;small ribosomal subunit;1.99227983947358e-09!GO:0065007;biological regulation;2.58064413619658e-09!GO:0044432;endoplasmic reticulum part;2.73004408419216e-09!GO:0000323;lytic vacuole;3.10321027846118e-09!GO:0005764;lysosome;3.10321027846118e-09!GO:0044248;cellular catabolic process;3.61529748706487e-09!GO:0044455;mitochondrial membrane part;3.61529748706487e-09!GO:0008565;protein transporter activity;4.27980763653369e-09!GO:0007242;intracellular signaling cascade;5.35431264858933e-09!GO:0007264;small GTPase mediated signal transduction;5.92291408509504e-09!GO:0008639;small protein conjugating enzyme activity;7.71186024542239e-09!GO:0007243;protein kinase cascade;7.96246061188165e-09!GO:0015934;large ribosomal subunit;8.58891105400278e-09!GO:0007049;cell cycle;9.06761445421333e-09!GO:0004842;ubiquitin-protein ligase activity;9.4977224354788e-09!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;9.82909727185332e-09!GO:0003676;nucleic acid binding;1.1764823341951e-08!GO:0006950;response to stress;1.254256850639e-08!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);1.70940724715588e-08!GO:0017038;protein import;1.77422371670389e-08!GO:0005746;mitochondrial respiratory chain;1.86783965244301e-08!GO:0000398;nuclear mRNA splicing, via spliceosome;2.12047388124317e-08!GO:0000375;RNA splicing, via transesterification reactions;2.12047388124317e-08!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;2.12047388124317e-08!GO:0051246;regulation of protein metabolic process;2.21157066528937e-08!GO:0008135;translation factor activity, nucleic acid binding;2.25579321123811e-08!GO:0007010;cytoskeleton organization and biogenesis;2.61753656764302e-08!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);2.93849711926641e-08!GO:0019787;small conjugating protein ligase activity;3.44081308521144e-08!GO:0016481;negative regulation of transcription;3.76648348039726e-08!GO:0050136;NADH dehydrogenase (quinone) activity;3.77659071952601e-08!GO:0003954;NADH dehydrogenase activity;3.77659071952601e-08!GO:0008137;NADH dehydrogenase (ubiquinone) activity;3.77659071952601e-08!GO:0005730;nucleolus;3.7905884146729e-08!GO:0031324;negative regulation of cellular metabolic process;3.94340885983135e-08!GO:0048522;positive regulation of cellular process;4.33893005584247e-08!GO:0003924;GTPase activity;4.34442242995168e-08!GO:0005635;nuclear envelope;5.06786605052982e-08!GO:0006606;protein import into nucleus;5.26881138954308e-08!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;5.73799309222588e-08!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;6.18483373041552e-08!GO:0016310;phosphorylation;6.2691375486009e-08!GO:0030695;GTPase regulator activity;6.86301369525054e-08!GO:0051170;nuclear import;7.00317182963997e-08!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;7.44390132442819e-08!GO:0042981;regulation of apoptosis;8.18787182592274e-08!GO:0009966;regulation of signal transduction;8.22787916664383e-08!GO:0006897;endocytosis;9.94262684350057e-08!GO:0010324;membrane invagination;9.94262684350057e-08!GO:0006446;regulation of translational initiation;9.94262684350057e-08!GO:0016070;RNA metabolic process;1.04358293260724e-07!GO:0043067;regulation of programmed cell death;1.23056287795321e-07!GO:0019899;enzyme binding;1.23056287795321e-07!GO:0009892;negative regulation of metabolic process;1.77743937632982e-07!GO:0043069;negative regulation of programmed cell death;1.96229032404051e-07!GO:0003714;transcription corepressor activity;2.41538441330396e-07!GO:0003743;translation initiation factor activity;2.41890260146382e-07!GO:0031965;nuclear membrane;2.51076525788293e-07!GO:0043066;negative regulation of apoptosis;2.53600352712804e-07!GO:0005524;ATP binding;2.58235802461534e-07!GO:0007265;Ras protein signal transduction;2.99760894332472e-07!GO:0032559;adenyl ribonucleotide binding;3.01919189545303e-07!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;3.42563107953e-07!GO:0007249;I-kappaB kinase/NF-kappaB cascade;3.48867905641515e-07!GO:0048518;positive regulation of biological process;3.7892637717318e-07!GO:0030554;adenyl nucleotide binding;6.40213936592052e-07!GO:0048475;coated membrane;6.44286500775151e-07!GO:0030117;membrane coat;6.44286500775151e-07!GO:0006325;establishment and/or maintenance of chromatin architecture;7.39664011670446e-07!GO:0042775;organelle ATP synthesis coupled electron transport;9.59581424229394e-07!GO:0042773;ATP synthesis coupled electron transport;9.59581424229394e-07!GO:0005788;endoplasmic reticulum lumen;9.61857299196964e-07!GO:0044440;endosomal part;1.0033804208086e-06!GO:0010008;endosome membrane;1.0033804208086e-06!GO:0006916;anti-apoptosis;1.02313850244799e-06!GO:0030964;NADH dehydrogenase complex (quinone);1.18179563746972e-06!GO:0045271;respiratory chain complex I;1.18179563746972e-06!GO:0005747;mitochondrial respiratory chain complex I;1.18179563746972e-06!GO:0043566;structure-specific DNA binding;1.1845791657393e-06!GO:0005083;small GTPase regulator activity;1.19488407884142e-06!GO:0006413;translational initiation;1.19488407884142e-06!GO:0051082;unfolded protein binding;1.24435529201835e-06!GO:0003779;actin binding;1.41506038910345e-06!GO:0016881;acid-amino acid ligase activity;1.60830396408984e-06!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;1.66726433886298e-06!GO:0006357;regulation of transcription from RNA polymerase II promoter;1.66891593686161e-06!GO:0005525;GTP binding;1.68470513807594e-06!GO:0008361;regulation of cell size;1.71022195532352e-06!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;1.81891956929077e-06!GO:0016563;transcription activator activity;1.81891956929077e-06!GO:0030120;vesicle coat;1.86447712912843e-06!GO:0030662;coated vesicle membrane;1.86447712912843e-06!GO:0051186;cofactor metabolic process;1.98306382072714e-06!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;2.35309732447638e-06!GO:0006323;DNA packaging;2.38049495747066e-06!GO:0016049;cell growth;2.602614444762e-06!GO:0005770;late endosome;2.82102530086866e-06!GO:0006888;ER to Golgi vesicle-mediated transport;3.16501851127396e-06!GO:0009060;aerobic respiration;3.16501851127396e-06!GO:0001726;ruffle;3.19286274084952e-06!GO:0044453;nuclear membrane part;3.23494656236802e-06!GO:0051726;regulation of cell cycle;4.15480811005151e-06!GO:0005096;GTPase activator activity;4.1638170124382e-06!GO:0000074;regulation of progression through cell cycle;4.36103562223646e-06!GO:0003713;transcription coactivator activity;4.42558142066527e-06!GO:0009056;catabolic process;4.49130800953612e-06!GO:0045333;cellular respiration;4.61392409073269e-06!GO:0045786;negative regulation of progression through cell cycle;4.627810962152e-06!GO:0008047;enzyme activator activity;5.7648756573197e-06!GO:0031980;mitochondrial lumen;5.78337435032395e-06!GO:0005759;mitochondrial matrix;5.78337435032395e-06!GO:0016879;ligase activity, forming carbon-nitrogen bonds;7.05656340529071e-06!GO:0015986;ATP synthesis coupled proton transport;7.75773364366613e-06!GO:0015985;energy coupled proton transport, down electrochemical gradient;7.75773364366613e-06!GO:0051276;chromosome organization and biogenesis;8.04477121017265e-06!GO:0019829;cation-transporting ATPase activity;9.19311923316435e-06!GO:0016197;endosome transport;9.20059435241936e-06!GO:0050657;nucleic acid transport;1.00898763360318e-05!GO:0051236;establishment of RNA localization;1.00898763360318e-05!GO:0050658;RNA transport;1.00898763360318e-05!GO:0042175;nuclear envelope-endoplasmic reticulum network;1.06973294849494e-05!GO:0005839;proteasome core complex (sensu Eukaryota);1.21420830921107e-05!GO:0030027;lamellipodium;1.22616517994678e-05!GO:0006403;RNA localization;1.23229856563466e-05!GO:0005789;endoplasmic reticulum membrane;1.27573734983102e-05!GO:0022402;cell cycle process;1.35137530602572e-05!GO:0006333;chromatin assembly or disassembly;1.46888547357596e-05!GO:0032561;guanyl ribonucleotide binding;1.50294444776268e-05!GO:0019001;guanyl nucleotide binding;1.50294444776268e-05!GO:0006613;cotranslational protein targeting to membrane;1.51478051610048e-05!GO:0001558;regulation of cell growth;2.02465914682302e-05!GO:0032446;protein modification by small protein conjugation;2.18608260092511e-05!GO:0005643;nuclear pore;2.31821715622297e-05!GO:0065004;protein-DNA complex assembly;2.49963219799075e-05!GO:0045045;secretory pathway;2.57306308275981e-05!GO:0003697;single-stranded DNA binding;2.64723740491841e-05!GO:0006099;tricarboxylic acid cycle;3.02808218758319e-05!GO:0046356;acetyl-CoA catabolic process;3.02808218758319e-05!GO:0016567;protein ubiquitination;3.08030632390913e-05!GO:0044431;Golgi apparatus part;3.08030632390913e-05!GO:0045892;negative regulation of transcription, DNA-dependent;3.97944611965941e-05!GO:0009055;electron carrier activity;4.01212938655406e-05!GO:0009150;purine ribonucleotide metabolic process;4.06232376498115e-05!GO:0032940;secretion by cell;4.13594848257577e-05!GO:0006732;coenzyme metabolic process;4.21492106886545e-05!GO:0009259;ribonucleotide metabolic process;4.21804814746039e-05!GO:0004386;helicase activity;5.063762838741e-05!GO:0031202;RNA splicing factor activity, transesterification mechanism;5.32608005658683e-05!GO:0006163;purine nucleotide metabolic process;5.52393306289951e-05!GO:0005769;early endosome;5.77936487300756e-05!GO:0007266;Rho protein signal transduction;5.8759004449354e-05!GO:0005798;Golgi-associated vesicle;6.54702681138799e-05!GO:0004298;threonine endopeptidase activity;7.19268618528172e-05!GO:0051187;cofactor catabolic process;7.58976474464039e-05!GO:0000151;ubiquitin ligase complex;7.74662190615207e-05!GO:0009109;coenzyme catabolic process;8.27431887188594e-05!GO:0048471;perinuclear region of cytoplasm;8.61683786467205e-05!GO:0065009;regulation of a molecular function;8.66914227126477e-05!GO:0042623;ATPase activity, coupled;8.99277832330475e-05!GO:0016772;transferase activity, transferring phosphorus-containing groups;0.000110852424431851!GO:0009199;ribonucleoside triphosphate metabolic process;0.00012014695251461!GO:0009152;purine ribonucleotide biosynthetic process;0.00012036110388818!GO:0009205;purine ribonucleoside triphosphate metabolic process;0.000123557562713205!GO:0009144;purine nucleoside triphosphate metabolic process;0.000123557562713205!GO:0008026;ATP-dependent helicase activity;0.000126154144554716!GO:0046034;ATP metabolic process;0.000140464047919426!GO:0005761;mitochondrial ribosome;0.000145650914531895!GO:0000313;organellar ribosome;0.000145650914531895!GO:0051028;mRNA transport;0.000146398873321082!GO:0048468;cell development;0.000146844687011103!GO:0009141;nucleoside triphosphate metabolic process;0.000147505298468294!GO:0016469;proton-transporting two-sector ATPase complex;0.00015443014975328!GO:0006974;response to DNA damage stimulus;0.000161108623727162!GO:0006084;acetyl-CoA metabolic process;0.000161108623727162!GO:0006164;purine nucleotide biosynthetic process;0.000162149615315208!GO:0016887;ATPase activity;0.000162909180661786!GO:0046930;pore complex;0.000166425689738938!GO:0016568;chromatin modification;0.000178931448753117!GO:0009260;ribonucleotide biosynthetic process;0.00020497693467058!GO:0006754;ATP biosynthetic process;0.000214549845821666!GO:0006753;nucleoside phosphate metabolic process;0.000214549845821666!GO:0030133;transport vesicle;0.000219014140821247!GO:0009142;nucleoside triphosphate biosynthetic process;0.000219196941442268!GO:0009201;ribonucleoside triphosphate biosynthetic process;0.000219196941442268!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;0.000224226580065076!GO:0009145;purine nucleoside triphosphate biosynthetic process;0.000224226580065076!GO:0045259;proton-transporting ATP synthase complex;0.000244092196990815!GO:0009967;positive regulation of signal transduction;0.00028131848197069!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;0.000284134648360221!GO:0065002;intracellular protein transport across a membrane;0.000294870557281664!GO:0000245;spliceosome assembly;0.000301781667818928!GO:0015078;hydrogen ion transmembrane transporter activity;0.000346829237041883!GO:0000785;chromatin;0.00035401519752559!GO:0003690;double-stranded DNA binding;0.000388511590086396!GO:0030532;small nuclear ribonucleoprotein complex;0.000390218177913983!GO:0030867;rough endoplasmic reticulum membrane;0.000495899807944815!GO:0008154;actin polymerization and/or depolymerization;0.000496907082138257!GO:0040008;regulation of growth;0.000503957592567701!GO:0005774;vacuolar membrane;0.000529062743743422!GO:0006334;nucleosome assembly;0.000535609620085569!GO:0005885;Arp2/3 protein complex;0.00057796509225102!GO:0006612;protein targeting to membrane;0.000604270967949864!GO:0045893;positive regulation of transcription, DNA-dependent;0.000614010686262335!GO:0030041;actin filament polymerization;0.000633263201397419!GO:0008286;insulin receptor signaling pathway;0.000633462919293128!GO:0019838;growth factor binding;0.000642831887292414!GO:0005694;chromosome;0.000702935732422477!GO:0005667;transcription factor complex;0.000721330149734998!GO:0005791;rough endoplasmic reticulum;0.00075539874315817!GO:0045941;positive regulation of transcription;0.000785738935659523!GO:0003724;RNA helicase activity;0.000859700180687746!GO:0005765;lysosomal membrane;0.000897750281981176!GO:0043623;cellular protein complex assembly;0.000946036506551493!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00102589300077259!GO:0051427;hormone receptor binding;0.00107535464069824!GO:0000278;mitotic cell cycle;0.00111062222345491!GO:0031902;late endosome membrane;0.00111062222345491!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.00112040124370352!GO:0005905;coated pit;0.0011692185429263!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.00117286621520826!GO:0000139;Golgi membrane;0.00118790124719199!GO:0015980;energy derivation by oxidation of organic compounds;0.00119406609665064!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;0.00122478231745668!GO:0042254;ribosome biogenesis and assembly;0.00134159150062651!GO:0008283;cell proliferation;0.00139276009458662!GO:0033116;ER-Golgi intermediate compartment membrane;0.00139687134429562!GO:0006607;NLS-bearing substrate import into nucleus;0.00140940523846021!GO:0015077;monovalent inorganic cation transmembrane transporter activity;0.0014883147168105!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.00155540275018785!GO:0031497;chromatin assembly;0.00162695383991481!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.00172992616572385!GO:0005813;centrosome;0.00173564912090412!GO:0044427;chromosomal part;0.00176886363546316!GO:0035257;nuclear hormone receptor binding;0.00190988078602966!GO:0005100;Rho GTPase activator activity;0.00194909240218813!GO:0030118;clathrin coat;0.0020704874191809!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;0.00208429551071274!GO:0006402;mRNA catabolic process;0.00215587560301604!GO:0008250;oligosaccharyl transferase complex;0.00225383399899281!GO:0016791;phosphoric monoester hydrolase activity;0.00225383399899281!GO:0051789;response to protein stimulus;0.00225383399899281!GO:0006986;response to unfolded protein;0.00225383399899281!GO:0015630;microtubule cytoskeleton;0.00230926718115643!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.00263034401003649!GO:0051128;regulation of cellular component organization and biogenesis;0.00272521854288449!GO:0044437;vacuolar part;0.00274115709430068!GO:0051056;regulation of small GTPase mediated signal transduction;0.00283195145528686!GO:0006260;DNA replication;0.00289946939074842!GO:0006281;DNA repair;0.00293264749140427!GO:0009719;response to endogenous stimulus;0.00296763408901522!GO:0005048;signal sequence binding;0.00301125033661681!GO:0030518;steroid hormone receptor signaling pathway;0.00302848871825048!GO:0008654;phospholipid biosynthetic process;0.00306022359725305!GO:0051168;nuclear export;0.00306022359725305!GO:0019222;regulation of metabolic process;0.00306807067613757!GO:0009615;response to virus;0.00314173484632086!GO:0042802;identical protein binding;0.0031669167234143!GO:0004576;oligosaccharyl transferase activity;0.00322331804621133!GO:0004674;protein serine/threonine kinase activity;0.00328343771582425!GO:0046578;regulation of Ras protein signal transduction;0.00357323093048519!GO:0006401;RNA catabolic process;0.00365507353701224!GO:0015629;actin cytoskeleton;0.00377170524474717!GO:0004721;phosphoprotein phosphatase activity;0.00385371044971569!GO:0051920;peroxiredoxin activity;0.00394714125605944!GO:0030132;clathrin coat of coated pit;0.00396806770433564!GO:0051101;regulation of DNA binding;0.0039932538349744!GO:0051188;cofactor biosynthetic process;0.0041130554177877!GO:0031589;cell-substrate adhesion;0.00414106813989561!GO:0003729;mRNA binding;0.00431207949642813!GO:0006891;intra-Golgi vesicle-mediated transport;0.00431207949642813!GO:0043021;ribonucleoprotein binding;0.00439490966117088!GO:0016301;kinase activity;0.00439490966117088!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.00448433109187057!GO:0030663;COPI coated vesicle membrane;0.00455392426679492!GO:0030126;COPI vesicle coat;0.00455392426679492!GO:0050790;regulation of catalytic activity;0.00469438350545451!GO:0048500;signal recognition particle;0.00493813645190781!GO:0008186;RNA-dependent ATPase activity;0.00500850014753055!GO:0005741;mitochondrial outer membrane;0.00524599435747799!GO:0017166;vinculin binding;0.00524877277047451!GO:0033673;negative regulation of kinase activity;0.00524877277047451!GO:0006469;negative regulation of protein kinase activity;0.00524877277047451!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.00537384677814306!GO:0016363;nuclear matrix;0.00546674242886458!GO:0009893;positive regulation of metabolic process;0.00568558173901757!GO:0006979;response to oxidative stress;0.00624704658774557!GO:0005815;microtubule organizing center;0.00624704658774557!GO:0005099;Ras GTPase activator activity;0.00645732087625808!GO:0030127;COPII vesicle coat;0.00653098760801445!GO:0012507;ER to Golgi transport vesicle membrane;0.00653098760801445!GO:0008139;nuclear localization sequence binding;0.00662914953498845!GO:0015631;tubulin binding;0.00663708682643243!GO:0016787;hydrolase activity;0.0066640033654265!GO:0007040;lysosome organization and biogenesis;0.00674207756626895!GO:0005057;receptor signaling protein activity;0.00697289205068655!GO:0031901;early endosome membrane;0.00723545662071613!GO:0050900;leukocyte migration;0.00734924778550673!GO:0030134;ER to Golgi transport vesicle;0.00735463965666745!GO:0007160;cell-matrix adhesion;0.00761041950612153!GO:0045187;regulation of circadian sleep/wake cycle, sleep;0.00762004158413805!GO:0004667;prostaglandin-D synthase activity;0.00762004158413805!GO:0050802;circadian sleep/wake cycle, sleep;0.00762004158413805!GO:0022410;circadian sleep/wake cycle process;0.00762004158413805!GO:0042749;regulation of circadian sleep/wake cycle;0.00762004158413805!GO:0045454;cell redox homeostasis;0.0076267963234628!GO:0006468;protein amino acid phosphorylation;0.00788540617758134!GO:0009117;nucleotide metabolic process;0.00789104205698343!GO:0019867;outer membrane;0.00790099655093891!GO:0022415;viral reproductive process;0.00790636848217949!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00797675857560574!GO:0045047;protein targeting to ER;0.00797675857560574!GO:0030137;COPI-coated vesicle;0.00813030283811669!GO:0006509;membrane protein ectodomain proteolysis;0.00887924921022437!GO:0033619;membrane protein proteolysis;0.00887924921022437!GO:0016859;cis-trans isomerase activity;0.00896187639076769!GO:0006414;translational elongation;0.00925044729296352!GO:0051336;regulation of hydrolase activity;0.00946122296632156!GO:0019904;protein domain specific binding;0.00954164963564858!GO:0043488;regulation of mRNA stability;0.00954164963564858!GO:0043487;regulation of RNA stability;0.00954164963564858!GO:0031968;organelle outer membrane;0.0095659294956052!GO:0016773;phosphotransferase activity, alcohol group as acceptor;0.00961499564371368!GO:0030384;phosphoinositide metabolic process;0.00981245141393148!GO:0005581;collagen;0.00991132043468816!GO:0030521;androgen receptor signaling pathway;0.00997553210226973!GO:0000902;cell morphogenesis;0.00997569241041055!GO:0032989;cellular structure morphogenesis;0.00997569241041055!GO:0001666;response to hypoxia;0.0100881483645768!GO:0007005;mitochondrion organization and biogenesis;0.0100881483645768!GO:0051674;localization of cell;0.0100881483645768!GO:0006928;cell motility;0.0100881483645768!GO:0051348;negative regulation of transferase activity;0.0102203370225235!GO:0001516;prostaglandin biosynthetic process;0.0102203370225235!GO:0046457;prostanoid biosynthetic process;0.0102203370225235!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.0102471852334265!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;0.0107903577787703!GO:0004812;aminoacyl-tRNA ligase activity;0.0107903577787703!GO:0016875;ligase activity, forming carbon-oxygen bonds;0.0107903577787703!GO:0030658;transport vesicle membrane;0.0108927064177478!GO:0006417;regulation of translation;0.0113664345108252!GO:0004004;ATP-dependent RNA helicase activity;0.0118136737742315!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.0120040548107232!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.0120040548107232!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.0120040548107232!GO:0022890;inorganic cation transmembrane transporter activity;0.012048856007747!GO:0030100;regulation of endocytosis;0.0122590043835302!GO:0012506;vesicle membrane;0.0125492795416706!GO:0022406;membrane docking;0.0126316346061919!GO:0048278;vesicle docking;0.0126316346061919!GO:0007167;enzyme linked receptor protein signaling pathway;0.012923373718266!GO:0008312;7S RNA binding;0.0129233995169986!GO:0007033;vacuole organization and biogenesis;0.013230389128159!GO:0006650;glycerophospholipid metabolic process;0.0134361673582801!GO:0018196;peptidyl-asparagine modification;0.0134746801363979!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.0134746801363979!GO:0009108;coenzyme biosynthetic process;0.0135850683504912!GO:0043087;regulation of GTPase activity;0.0137545726033328!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.0140546088775021!GO:0007050;cell cycle arrest;0.0149401377377267!GO:0031325;positive regulation of cellular metabolic process;0.0151449248794586!GO:0043038;amino acid activation;0.0151943334735043!GO:0006418;tRNA aminoacylation for protein translation;0.0151943334735043!GO:0043039;tRNA aminoacylation;0.0151943334735043!GO:0043065;positive regulation of apoptosis;0.0154344257552201!GO:0002474;antigen processing and presentation of peptide antigen via MHC class I;0.0156162153190363!GO:0006904;vesicle docking during exocytosis;0.0156624121592733!GO:0016281;eukaryotic translation initiation factor 4F complex;0.0160108735306519!GO:0051252;regulation of RNA metabolic process;0.0161089567360026!GO:0006752;group transfer coenzyme metabolic process;0.0163422754680248!GO:0007179;transforming growth factor beta receptor signaling pathway;0.0165732345218359!GO:0001725;stress fiber;0.0166692813670902!GO:0032432;actin filament bundle;0.0166692813670902!GO:0030865;cortical cytoskeleton organization and biogenesis;0.0167482201660797!GO:0005852;eukaryotic translation initiation factor 3 complex;0.016761162574234!GO:0019843;rRNA binding;0.0168590509701602!GO:0030522;intracellular receptor-mediated signaling pathway;0.016922911081017!GO:0004185;serine carboxypeptidase activity;0.0170484789108995!GO:0016311;dephosphorylation;0.0171636705089025!GO:0005862;muscle thin filament tropomyosin;0.0177064281927593!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.0178834579256584!GO:0035023;regulation of Rho protein signal transduction;0.0178834579256584!GO:0051045;negative regulation of membrane protein ectodomain proteolysis;0.0178834579256584!GO:0051043;regulation of membrane protein ectodomain proteolysis;0.0178834579256584!GO:0035035;histone acetyltransferase binding;0.0178834579256584!GO:0060090;molecular adaptor activity;0.0180123204042118!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.0185343280331466!GO:0018193;peptidyl-amino acid modification;0.0189817586774637!GO:0043068;positive regulation of programmed cell death;0.0192496287656187!GO:0051098;regulation of binding;0.0192679265935102!GO:0045944;positive regulation of transcription from RNA polymerase II promoter;0.0192679265935102!GO:0008234;cysteine-type peptidase activity;0.019343149652377!GO:0006643;membrane lipid metabolic process;0.0197571765469016!GO:0004672;protein kinase activity;0.0199296444348326!GO:0046822;regulation of nucleocytoplasmic transport;0.0202677242293798!GO:0007034;vacuolar transport;0.0209236510130654!GO:0046467;membrane lipid biosynthetic process;0.021055036479371!GO:0019902;phosphatase binding;0.021055036479371!GO:0048487;beta-tubulin binding;0.0217019997517177!GO:0006376;mRNA splice site selection;0.0222056805036613!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0222056805036613!GO:0006693;prostaglandin metabolic process;0.0222435656041291!GO:0006692;prostanoid metabolic process;0.0222435656041291!GO:0035258;steroid hormone receptor binding;0.0222568250504642!GO:0007229;integrin-mediated signaling pathway;0.022442470549175!GO:0051235;maintenance of localization;0.0225947926005965!GO:0008383;manganese superoxide dismutase activity;0.0233170371443564!GO:0001315;age-dependent response to reactive oxygen species;0.0233170371443564!GO:0044433;cytoplasmic vesicle part;0.0233626081702121!GO:0030659;cytoplasmic vesicle membrane;0.0233828446802754!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0235579678350556!GO:0046983;protein dimerization activity;0.023904296208406!GO:0051329;interphase of mitotic cell cycle;0.0239123342635018!GO:0005085;guanyl-nucleotide exchange factor activity;0.0240444694730165!GO:0005062;hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity;0.0241374001460779!GO:0017015;regulation of transforming growth factor beta receptor signaling pathway;0.0244105990890932!GO:0004177;aminopeptidase activity;0.0245227181274345!GO:0051049;regulation of transport;0.0247046616731325!GO:0016584;nucleosome positioning;0.0248933212409947!GO:0051325;interphase;0.0253168080451098!GO:0030119;AP-type membrane coat adaptor complex;0.0253544395811405!GO:0005518;collagen binding;0.026605446542282!GO:0031326;regulation of cellular biosynthetic process;0.026605446542282!GO:0030660;Golgi-associated vesicle membrane;0.0267073811813581!GO:0015036;disulfide oxidoreductase activity;0.0269629901413315!GO:0008354;germ cell migration;0.0277125492175016!GO:0003702;RNA polymerase II transcription factor activity;0.0277145417206393!GO:0004722;protein serine/threonine phosphatase activity;0.0278494126950277!GO:0006364;rRNA processing;0.0291969928721856!GO:0046474;glycerophospholipid biosynthetic process;0.0300497037634457!GO:0030155;regulation of cell adhesion;0.0302179242826269!GO:0000059;protein import into nucleus, docking;0.0302179242826269!GO:0003725;double-stranded RNA binding;0.0304609272429646!GO:0031529;ruffle organization and biogenesis;0.0306705889744446!GO:0002504;antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;0.0306705889744446!GO:0051179;localization;0.0310293792251556!GO:0030569;chymotrypsin inhibitor activity;0.0310293792251556!GO:0008147;structural constituent of bone;0.0314830629443261!GO:0006892;post-Golgi vesicle-mediated transport;0.0317183954597776!GO:0030199;collagen fibril organization;0.032598286637212!GO:0047485;protein N-terminus binding;0.0332987154392064!GO:0005869;dynactin complex;0.0335971635534486!GO:0030131;clathrin adaptor complex;0.0337880364355279!GO:0003682;chromatin binding;0.0340949453346451!GO:0051540;metal cluster binding;0.0340949453346451!GO:0051536;iron-sulfur cluster binding;0.0340949453346451!GO:0000060;protein import into nucleus, translocation;0.034127276297432!GO:0030258;lipid modification;0.0349015328379793!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.0349015328379793!GO:0015399;primary active transmembrane transporter activity;0.0349015328379793!GO:0004437;inositol or phosphatidylinositol phosphatase activity;0.0353054661043896!GO:0007041;lysosomal transport;0.0353236296395851!GO:0044262;cellular carbohydrate metabolic process;0.0353605447011656!GO:0000209;protein polyubiquitination;0.0353927313459055!GO:0050811;GABA receptor binding;0.0357790574962743!GO:0008287;protein serine/threonine phosphatase complex;0.0357904992085969!GO:0016072;rRNA metabolic process;0.0365998915406573!GO:0006672;ceramide metabolic process;0.0367926818257811!GO:0046489;phosphoinositide biosynthetic process;0.0368856846047892!GO:0005088;Ras guanyl-nucleotide exchange factor activity;0.0368856846047892!GO:0046870;cadmium ion binding;0.0372970833943708!GO:0031349;positive regulation of defense response;0.0373584619516789!GO:0050729;positive regulation of inflammatory response;0.0373584619516789!GO:0005637;nuclear inner membrane;0.037470329313773!GO:0004563;beta-N-acetylhexosaminidase activity;0.0379932998267323!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.0380960432432639!GO:0002253;activation of immune response;0.038917482251631!GO:0007030;Golgi organization and biogenesis;0.0390526285390063!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.040184485535489!GO:0006470;protein amino acid dephosphorylation;0.0409850180378886!GO:0032906;transforming growth factor-beta2 production;0.041224547364932!GO:0032909;regulation of transforming growth factor-beta2 production;0.041224547364932!GO:0005583;fibrillar collagen;0.0413650147709078!GO:0045792;negative regulation of cell size;0.0426099920532924!GO:0016853;isomerase activity;0.0434008730057772!GO:0051493;regulation of cytoskeleton organization and biogenesis;0.0437960825796717!GO:0033043;regulation of organelle organization and biogenesis;0.0437960825796717!GO:0030984;kininogen binding;0.0437960825796717!GO:0004213;cathepsin B activity;0.0437960825796717!GO:0002757;immune response-activating signal transduction;0.0448417324077089!GO:0032763;regulation of mast cell cytokine production;0.0450782455255879!GO:0032762;mast cell cytokine production;0.0450782455255879!GO:0031625;ubiquitin protein ligase binding;0.0455162012350606!GO:0051087;chaperone binding;0.0455162012350606!GO:0030135;coated vesicle;0.0460275560551716!GO:0030866;cortical actin cytoskeleton organization and biogenesis;0.0464159283780505!GO:0016740;transferase activity;0.0464159283780505!GO:0004197;cysteine-type endopeptidase activity;0.0473260234766735!GO:0042578;phosphoric ester hydrolase activity;0.0479466286419348!GO:0045663;positive regulation of myoblast differentiation;0.0493835384758412
|sample_id=10041
|sample_note=
|sample_sex=female
|sample_species=Human (Homo sapiens)
|sample_strain=
|sample_tissue=dura mater
|top_motifs=NFATC1..3:2.38188447613;HBP1_HMGB_SSRP1_UBTF:2.31912989734;PRDM1:2.27523902456;GCM1,2:2.25893084772;MTF1:2.20272325754;TLX2:2.03642001632;ZNF238:1.99363551287;MYFfamily:1.96256646933;TFAP2{A,C}:1.92747983803;SOX5:1.88568203051;MYBL2:1.87330444204;EP300:1.87256459524;MTE{core}:1.85805643842;STAT2,4,6:1.79542984815;MED-1{core}:1.74834531963;MZF1:1.72684422624;MAZ:1.72066324439;GATA4:1.67514392496;RREB1:1.57309208179;HIC1:1.56562061346;GTF2I:1.45823722713;PATZ1:1.42507325884;TFCP2:1.41884793802;EGR1..3:1.38358043354;IRF7:1.38190099895;TFAP2B:1.36751669607;TLX1..3_NFIC{dimer}:1.36553608332;STAT1,3:1.35465313895;IRF1,2:1.32024008139;IKZF1:1.31426969449;NFIL3:1.26598609011;TBP:1.20091102755;SP1:1.19855095322;POU5F1:1.17519983958;FOXO1,3,4:1.16282960898;SRF:1.13526354229;HMX1:1.12960047049;EBF1:1.10872029336;TFDP1:1.09997292461;FOX{I1,J2}:1.09302089275;AR:1.08639280687;PAX5:1.06894608147;SMAD1..7,9:1.05378867361;BREu{core}:1.05193312962;FOX{D1,D2}:1.00565649013;TGIF1:1.00004222479;ZFP161:0.992270208725;ETS1,2:0.98500669187;FOXA2:0.97513813826;RBPJ:0.969226978262;XBP1:0.965520911749;ZIC1..3:0.936008766908;GFI1B:0.903356427712;TFAP4:0.903167582066;T:0.878216399882;RXRA_VDR{dimer}:0.877751005046;MEF2{A,B,C,D}:0.870988215727;TOPORS:0.86872284404;SPIB:0.818154082409;BPTF:0.748983170142;XCPE1{core}:0.67702438286;ATF2:0.659570704829;SOX{8,9,10}:0.653052968507;ZNF423:0.643789221675;DMAP1_NCOR{1,2}_SMARC:0.605501272876;HAND1,2:0.583865693478;ESR1:0.582753182426;GLI1..3:0.553806494121;SREBF1,2:0.552304170858;PAX1,9:0.548230864598;SPI1:0.545440107065;RXR{A,B,G}_{NR1H2,PPAR}dimers:0.543840357385;ELF1,2,4:0.537635595019;ATF6:0.533761509411;TEAD1:0.523305102042;REST:0.522272196645;SPZ1:0.514944691475;GTF2A1,2:0.487522774435;NKX3-2:0.46802998085;ZNF384:0.462822948898;NHLH1,2:0.441948550759;IKZF2:0.427424535958;NR3C1:0.423332556691;KLF4:0.414061365882;NANOG:0.412687273294;RFX2..5_RFXANK_RFXAP:0.403090532059;ALX4:0.396224658222;POU2F1..3:0.393824830432;RUNX1..3:0.375360646824;CEBPA,B_DDIT3:0.367351892722;FOXP1:0.358210457852;MAFB:0.35649696868;NR1H4:0.327876263825;AHR_ARNT_ARNT2:0.327236603579;RFX1:0.322424701049;NANOG{mouse}:0.315798717936;POU6F1:0.281537646624;FOXN1:0.276632110671;ZNF148:0.260554213902;FOXP3:0.259019085128;DBP:0.256233880696;GFI1:0.251599821201;JUN:0.241704986052;SOX2:0.238797084088;GZF1:0.225853671925;HMGA1,2:0.175078314467;RORA:0.147939864467;RXR{A,B,G}:0.132484898072;ALX1:0.111952269625;ATF4:0.0951691582753;PRRX1,2:0.0941553462472;EVI1:0.0412043936842;CDC5L:0.029248441597;GATA6:0.0221981455912;ZBTB6:0.0186109850494;TAL1_TCF{3,4,12}:0.00553906512875;FOX{F1,F2,J1}:-0.00242064133618;CREB1:-0.0209544626105;TBX4,5:-0.0393131875715;ARID5B:-0.0398419895747;VSX1,2:-0.0418044179285;NKX6-1,2:-0.0647426854638;HNF1A:-0.0679249550128;HNF4A_NR2F1,2:-0.0917051524743;HES1:-0.0961850405979;PAX3,7:-0.111682011324;MYOD1:-0.125387038008;ESRRA:-0.140584561866;FOXL1:-0.146264679552;FOSL2:-0.16242546128;NFE2L2:-0.186508648528;NFKB1_REL_RELA:-0.197669641156;CRX:-0.203857591172;PAX2:-0.220340244073;CUX2:-0.225715663763;NFY{A,B,C}:-0.226189186;ADNP_IRX_SIX_ZHX:-0.233899427053;AIRE:-0.234097606729;HLF:-0.237264923539;OCT4_SOX2{dimer}:-0.237313564485;PDX1:-0.242317465221;NKX2-1,4:-0.250483688922;NFE2:-0.2565795346;HIF1A:-0.259288800748;SOX17:-0.272317113169;EN1,2:-0.326223330007;E2F1..5:-0.396357935189;NKX2-3_NKX2-5:-0.42571723225;FOS_FOS{B,L1}_JUN{B,D}:-0.44374599818;PITX1..3:-0.462435485653;SNAI1..3:-0.519078604212;LEF1_TCF7_TCF7L1,2:-0.543728950206;ATF5_CREB3:-0.546533265496;BACH2:-0.556486863097;HOX{A4,D4}:-0.588425855558;bHLH_family:-0.594510358565;LMO2:-0.596927724261;NFIX:-0.604928456514;NFE2L1:-0.632925300177;UFEwm:-0.701028131946;NR6A1:-0.711590189275;ZNF143:-0.71298297248;POU3F1..4:-0.716082844182;TEF:-0.720915691184;HSF1,2:-0.728382677173;NRF1:-0.775760154633;NR5A1,2:-0.779048422289;TP53:-0.785056129828;ZEB1:-0.807590351951;PBX1:-0.82249338144;FOXM1:-0.832677760139;HOX{A5,B5}:-0.842967403548;NKX2-2,8:-0.862424218005;ZBTB16:-0.890344263268;FOXD3:-0.940554233496;HOX{A6,A7,B6,B7}:-0.95932371243;POU1F1:-0.961766062301;CDX1,2,4:-0.993442398379;MYB:-1.0029575786;PAX4:-1.00795709681;YY1:-1.11127265964;NKX3-1:-1.13519940617;PAX8:-1.16534565687;PPARG:-1.2800734735;LHX3,4:-1.33004554049;PAX6:-1.35388547496;ELK1,4_GABP{A,B1}:-1.36284984225;FOXQ1:-1.37364142953;ONECUT1,2:-1.48839982082;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-1.69802226449;STAT5{A,B}:-2.02372922527;HOXA9_MEIS1:-2.43930615992
|xref=
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10041-101F5;search_select_hide=table117:FF:10041-101F5
}}
}}

Latest revision as of 12:16, 3 June 2020

Name:dura mater, adult, donor1
Species:Human (Homo sapiens)
Library ID:CNhs10648
Sample type:tissues
Genomic View: UCSC
RefEX:Specific genes
FANTOM CAT:1, 2
CAGEd-oPOSSUM:link
ZENBU report :link
Additional information
Sample information
strainNA
tissuedura mater
dev stage59 years old adult
sexfemale
ageNA
cell typeCELL MIXTURE - tissue sample
cell lineNA
companyClontech
collaborationFANTOM5 OSC CORE (contact: Al Forrest)
External link for information[{{{sample_info_link}}} {{{sample_info_link}}}]
RNA information
lot number3040808
catalog numberCat:636588
sample typetotal RNA
extraction protocol (Details)OP-RNA-extraction-totalRNA-TRIzol-isopropanol-v1.0

CAGE Accession numbers
MethodSample accession id
CAGE  SAMD00005192
Library accession numbers

Library idMethodExp. accession idRun accession id
CNhs10648 CAGE DRX008647 DRR009519
Accession ID Hg19

Library idBAMCTSS
CNhs10648 DRZ000944 DRZ002329
Accession ID Hg38

Library idBAMCTSS
CNhs10648 DRZ012294 DRZ013679
Download raw sequence, BAM & CTSS
Hg19
FastaBAMCTSS
downloaddownloaddonwload
Hg38
BAMCTSS
downloaddonwload


Relative expression to median (log10)


Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.



Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data



Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data



TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample


JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data

library id: CNhs10648



FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data

library id: CNhs10648



de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br> library id: CNhs10648


FANTOM5 (FF) ontology


Direct parent terms


Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data

UBERON: Anatomy
0000468 (multi-cellular organism)
0007023 (adult organism)
0002363 (dura mater)
0002360 (meninx)
0000479 (tissue)
0004121 (ectoderm-derived structure)
0010314 (structure with developmental contribution from neural crest)
0011216 (organ system subdivision)
0000062 (organ)
0004120 (mesoderm-derived structure)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0000477 (anatomical cluster)
0000467 (anatomical system)
0001062 (anatomical entity)
0000480 (anatomical group)
0000094 (membrane organ)
0010317 (germ layer / neural crest derived structure)
0001017 (central nervous system)
0001016 (nervous system)
0010743 (meningeal cluster)

FF: FANTOM5
0000102 (sample by type)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0000998 (adult tissue sample)
0000004 (tissue sample)
0010041 (human dura mater - adult sample)

Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
UBERON:0002532 (epiblast (generic))
UBERON:0006601 (presumptive ectoderm)
UBERON:0006603 (presumptive mesoderm)
UBERON:0010115 (future dura mater)
UBERON:0010316 (germ layer / neural crest)