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{{UBERON
{{UBERON
|id=UBERON:0000964
|alt_id=UBERON:FBbt_00004191-FMA_58238-MA_0000266-XAO_0000180-ZFA_0000640
|name=cornea
|namespace=
|def="transparent front part of the eye that covers the iris, pupil, and anterior chamber. Together with the lens, the cornea refracts light, accounting for approximately two-thirds of the eye's total optical power." [Wikipedia:Cornea]
|xref=AAO:0010344;;BTO:0000286;;EFO:0000377;;EHDAA2:0000316;;EHDAA:10199;;EMAPA:17161;;EV:0100341;;FMA:58238;;GAID:892;;http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg;;http://upload.wikimedia.org/wikipedia/commons/thumb/1/1e/Schematic_diagram_of_the_human_eye_en.svg/200px-Schematic_diagram_of_the_human_eye_en.svg.png;;MA:0000266;;MESH:A.09.371.060.217;;ncithesaurus:Cornea;;OpenCyc:Mx4rvViBa5wpEbGdrcN5Y29ycA;;SCTID:181162001;;TAO:0000640;;VHOG:0000164;;XAO:0000180;;ZFA:0000640
|is_a=UBERON:0003102;;UBERON:0010313
|synonym="tunica cornea" RELATED []
|comment=
|comment=
|alt_id=UBERON:FBbt_00004191-FMA_58238-MA_0000266-XAO_0000180-ZFA_0000640
|disjoint_from=
|union_of=
|created_by=
|created_by=
|obo_creation_date=
|def="transparent front part of the eye that covers the iris, pupil, and anterior chamber. Together with the lens, the cornea refracts light, accounting for approximately two-thirds of the eye's total optical power." [Wikipedia:Cornea]
|subset=uberon_slim;;vertebrate_core
|derives_from=
|derives_from=
|develops_from=UBERON:0004348;;UBERON:0005427
|develops_from=UBERON:0004348;;UBERON:0005427
|disjoint_from=
|has_quality=
|has_quality=
|id=UBERON:0000964
|is_a=UBERON:0003102 ;;UBERON:0010313
|is_obsolete=
|located_in=
|located_in=
|part_of=UBERON:0001801;;UBERON:0010409
|name=cornea
|namespace=
|obo_creation_date=
|part_of=UBERON:0001801;;UBERON:0010409;;UBERON:0012430
|preceded_by=
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl-to-uberon.owl;;IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl-to-uberon.owl;;IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl
|is_obsolete=
|subset=uberon_slim;;vertebrate_core
|preceded_by=
|synonym="tunica cornea" RELATED []
|union_of=
|xref=AAO:0010344;;BTO:0000286;;EFO:0000377;;EHDAA2:0000316;;EHDAA:10199;;EMAPA:17161;;EV:0100341;;FMA:58238;;GAID:892;;http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg;;http://upload.wikimedia.org/wikipedia/commons/thumb/1/1e/Schematic_diagram_of_the_human_eye_en.svg/200px-Schematic_diagram_of_the_human_eye_en.svg.png;;MA:0000266;;MESH:A.09.371.060.217;;ncithesaurus:Cornea;;OpenCyc:Mx4rvViBa5wpEbGdrcN5Y29ycA;;SCTID:181162001;;TAO:0000640;;VHOG:0000164;;XAO:0000180;;ZFA:0000640
}}
}}

Revision as of 10:57, 12 September 2014

Name:cornea
Definition:"transparent front part of the eye that covers the iris, pupil, and anterior chamber. Together with the lens, the cornea refracts light, accounting for approximately two-thirds of the eye's total optical power." [Wikipedia:Cornea]
Xrefs:
links:

AAO:0010344
BTO:0000286
EFO:0000377
EHDAA2:0000316
EHDAA:10199
EMAPA:17161
EV:0100341
FMA:58238
GAID:892
[1]
[ 200px-Schematic_diagram_of_the_human_eye_en.svg.png 200px-Schematic_diagram_of_the_human_eye_en.svg.png]
MA:0000266
MESH:A.09.371.060.217
ncithesaurus:Cornea
OpenCyc:Mx4rvViBa5wpEbGdrcN5Y29ycA
SCTID:181162001
TAO:0000640
VHOG:0000164
XAO:0000180

ZFA:0000640
Synonyms: "tunica cornea" RELATED []
Alt_id: UBERON:FBbt_00004191-FMA_58238-MA_0000266-XAO_0000180-ZFA_0000640
Subset: uberon_slim
vertebrate_core

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:UBERON:0003102(surface structure),UBERON:0010313(neural crest-derived structure)
develops_from:UBERON:0004348(optic eminence),UBERON:0005427(corneal primordium)
part_of:UBERON:0001801(anterior segment of eyeball),UBERON:0010409(eye surface),UBERON:0012430(tunica fibrosa of eyeball)



Children

part of:CL:0000575 (corneal epithelial cell),UBERON:0001777 (substantia propria of cornea)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology

Human (Homo sapiens)


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0000964 (cornea), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
4.67e-66FFCP PHASE1:Hg19::chr17:39023189..39023197,-#_2ff9d1d71947082ce8fe1888ca5fafe8p2@KRT12
4.67e-66FFCP PHASE2:Hg19::chr17:39023189..39023197,-#_2ff9d1d71947082ce8fe1888ca5fafe8p2@KRT12
3.1e-50FFCP PHASE1:Hg19::chr3:52362029..52362031,+#_77abf304917189d16d6d64d5687dd983p@chr3:52362029..52362031, +
3.1e-50FFCP PHASE2:Hg19::chr7:150910973..150910976,-#_77abf304917189d16d6d64d5687dd983p@chr7:150910973..150910976, -
3.1e-50FFCP PHASE2:Hg19::chr3:52362029..52362031,+#_77abf304917189d16d6d64d5687dd983p@chr3:52362029..52362031, +
3.1e-50FFCP PHASE1:Hg19::chr7:150910973..150910976,-#_77abf304917189d16d6d64d5687dd983p@chr7:150910973..150910976, -
3.31e-40FFCP PHASE1:Hg19::chr12:53189894..53189905,-#_90f2e9066280b50b926dc8cdec7f33eap1@KRT3
3.31e-40FFCP PHASE2:Hg19::chr12:53189894..53189905,-#_90f2e9066280b50b926dc8cdec7f33eap1@KRT3
5.98e-34FFCP PHASE1:Hg19::chr22:30144620..30144638,-#_44432c199e26cf85044c5f0732ead873p7@ZMAT5
5.98e-34FFCP PHASE2:Hg19::chr22:30144620..30144638,-#_44432c199e26cf85044c5f0732ead873p7@ZMAT5
1.17e-33FFCP PHASE2:Hg19::chr8:124206334..124206344,+#_454aec2fb3796f540b7085aa35773a06p@chr8:124206334..124206344, +
1.17e-33FFCP PHASE1:Hg19::chr8:124206334..124206344,+#_454aec2fb3796f540b7085aa35773a06p@chr8:124206334..124206344, +
3.16e-29FFCP PHASE2:Hg19::chr1:19403546..19403571,-#_7c2f21565d38af5774fe6d82719c956dp@chr1:19403546..19403571, -
3.16e-29FFCP PHASE1:Hg19::chr7:1600419..1600429,-#_7c2f21565d38af5774fe6d82719c956dp11@TMEM184A
3.16e-29FFCP PHASE2:Hg19::chr7:1600419..1600429,-#_7c2f21565d38af5774fe6d82719c956dp11@TMEM184A
3.16e-29FFCP PHASE1:Hg19::chr1:19403546..19403571,-#_7c2f21565d38af5774fe6d82719c956dp@chr1:19403546..19403571, -
5.61e-29FFCP PHASE1:Hg19::chr12:48164790..48164808,-#_aa717f83d141a7a36f50414d77bc8be5p16@RAPGEF3
5.61e-29FFCP PHASE2:Hg19::chr12:48164790..48164808,-#_aa717f83d141a7a36f50414d77bc8be5p16@RAPGEF3
5.61e-29FFCP PHASE1:Hg19::chr20:43743762..43743770,-#_aa717f83d141a7a36f50414d77bc8be5p3@WFDC5
5.61e-29FFCP PHASE2:Hg19::chr20:43743762..43743770,-#_aa717f83d141a7a36f50414d77bc8be5p3@WFDC5
5.56e-26FFCP PHASE2:Hg19::chr16:3014251..3014254,+#_3a2be84488e7359e2a978f2dfc284e8dp3@KREMEN2
5.56e-26FFCP PHASE1:Hg19::chr16:3014251..3014254,+#_3a2be84488e7359e2a978f2dfc284e8dp3@KREMEN2
6.73e-26FFCP PHASE1:Hg19::chr6:35048829..35048844,+#_c7c1c1821dba5de92fd694c6c4a2489ap@chr6:35048829..35048844, +
6.73e-26FFCP PHASE2:Hg19::chr6:35048829..35048844,+#_c7c1c1821dba5de92fd694c6c4a2489ap@chr6:35048829..35048844, +
7.14e-26FFCP PHASE2:Hg19::chr6:113369869..113369877,+#_cf028f33186ae6d9b8db5c57f6e98c0ep@chr6:113369869..113369877, +
7.14e-26FFCP PHASE1:Hg19::chr10:92617531..92617541,-#_cf028f33186ae6d9b8db5c57f6e98c0ep8@HTR7
7.14e-26FFCP PHASE1:Hg19::chr8:22932230..22932233,-#_cf028f33186ae6d9b8db5c57f6e98c0ep5@ENST00000520840, p5@ENST00000523806
7.14e-26FFCP PHASE2:Hg19::chr15:49255230..49255248,-#_cf028f33186ae6d9b8db5c57f6e98c0ep16@SHC4
7.14e-26FFCP PHASE2:Hg19::chr8:22932230..22932233,-#_cf028f33186ae6d9b8db5c57f6e98c0ep5@ENST00000520840, p5@ENST00000523806
7.14e-26FFCP PHASE2:Hg19::chr16:56368957..56368963,+#_cf028f33186ae6d9b8db5c57f6e98c0ep@chr16:56368957..56368963, +
7.14e-26FFCP PHASE2:Hg19::chr10:92617531..92617541,-#_cf028f33186ae6d9b8db5c57f6e98c0ep8@HTR7
7.14e-26FFCP PHASE1:Hg19::chr15:49255230..49255248,-#_cf028f33186ae6d9b8db5c57f6e98c0ep16@SHC4
7.14e-26FFCP PHASE1:Hg19::chr6:113369869..113369877,+#_cf028f33186ae6d9b8db5c57f6e98c0ep@chr6:113369869..113369877, +
7.14e-26FFCP PHASE1:Hg19::chr16:56368957..56368963,+#_cf028f33186ae6d9b8db5c57f6e98c0ep@chr16:56368957..56368963, +
8.66e-26FFCP PHASE1:Hg19::chr11:67463189..67463193,-#_23e0095269c37215df40651091552277p@chr11:67463189..67463193, -
8.66e-26FFCP PHASE2:Hg19::chr11:67463189..67463193,-#_23e0095269c37215df40651091552277p@chr11:67463189..67463193, -
1.0e-22FFCP PHASE1:Hg19::chr12:46897588..46897603,+#_9b81283dcf9e5cad4b012a567762323ap@chr12:46897588..46897603, +
1.0e-22FFCP PHASE2:Hg19::chr12:46897588..46897603,+#_9b81283dcf9e5cad4b012a567762323ap@chr12:46897588..46897603, +
1.12e-22FFCP PHASE2:Hg19::chr13:20934450..20934456,+#_582f88348edc7fa2eb05e2a0f981118dp@chr13:20934450..20934456, +
1.12e-22FFCP PHASE1:Hg19::chr13:20934450..20934456,+#_582f88348edc7fa2eb05e2a0f981118dp@chr13:20934450..20934456, +
1.25e-22FFCP PHASE1:Hg19::chr19:51538096..51538109,-#_187bf8317fc6de318046bfc96da90f02p5@KLK12
1.25e-22FFCP PHASE2:Hg19::chr19:51538096..51538109,-#_187bf8317fc6de318046bfc96da90f02p5@KLK12
5.17e-21FFCP PHASE1:Hg19::chr10:5529595..5529606,-#_8143d1daf838796b708f9f02e9ba770cp@chr10:5529595..5529606, -
5.17e-21FFCP PHASE2:Hg19::chr10:5529595..5529606,-#_8143d1daf838796b708f9f02e9ba770cp@chr10:5529595..5529606, -
7.74e-21FFCP PHASE1:Hg19::chr19:1249729..1249741,+#_5a005a1696a04d0374cbe1a399944a6ep19@MIDN
7.74e-21FFCP PHASE2:Hg19::chr19:1249729..1249741,+#_5a005a1696a04d0374cbe1a399944a6ep19@MIDN
1.15e-20FFCP PHASE1:Hg19::chr2:131669803..131669810,+#_43dd40ee521bc08db10ea8b2242090ccp@chr2:131669803..131669810, +
1.15e-20FFCP PHASE2:Hg19::chr2:131669803..131669810,+#_43dd40ee521bc08db10ea8b2242090ccp@chr2:131669803..131669810, +
1.28e-20FFCP PHASE1:Hg19::chr9:127212697..127212708,+#_d1ec072a97d7cf595d3a37dd7575d3c5p@chr9:127212697..127212708, +
1.28e-20FFCP PHASE2:Hg19::chr9:127212697..127212708,+#_d1ec072a97d7cf595d3a37dd7575d3c5p@chr9:127212697..127212708, +
1.56e-20FFCP PHASE1:Hg19::chr19:1905001..1905006,+#_43567b9bdefd8bbad845ada59bc40f32p11@SCAMP4
1.56e-20FFCP PHASE2:Hg19::chr19:1905001..1905006,+#_43567b9bdefd8bbad845ada59bc40f32p11@SCAMP4
1.9e-20FFCP PHASE2:Hg19::chr19:50709335..50709346,+#_e3f35f2630b59db25515a127f7617c6cp@chr19:50709335..50709346, +
1.9e-20FFCP PHASE2:Hg19::chr15:72490099..72490109,-#_e3f35f2630b59db25515a127f7617c6cp3@GRAMD2
1.9e-20FFCP PHASE1:Hg19::chr15:72490099..72490109,-#_e3f35f2630b59db25515a127f7617c6cp3@GRAMD2
1.9e-20FFCP PHASE1:Hg19::chr19:50709335..50709346,+#_e3f35f2630b59db25515a127f7617c6cp@chr19:50709335..50709346, +
2.76e-19FFCP PHASE1:Hg19::chr20:25176603..25176614,+#_785092416293ee0de4acf6a3e5ec9e85p@chr20:25176603..25176614, +
2.76e-19FFCP PHASE2:Hg19::chr20:25176603..25176614,+#_785092416293ee0de4acf6a3e5ec9e85p@chr20:25176603..25176614, +
6.77e-19FFCP PHASE1:Hg19::chr19:44306567..44306574,-#_f92c0443675481ca40d04d3c56a32e65p7@LYPD5
6.77e-19FFCP PHASE2:Hg19::chr19:44306567..44306574,-#_f92c0443675481ca40d04d3c56a32e65p7@LYPD5
8.88e-19FFCP PHASE1:Hg19::chr2:28853455..28853476,+#_8b5058e032517c667938c909de34d205p@chr2:28853455..28853476, +
8.88e-19FFCP PHASE2:Hg19::chr2:28853455..28853476,+#_8b5058e032517c667938c909de34d205p@chr2:28853455..28853476, +
9.72e-19FFCP PHASE1:Hg19::chr20:42816206..42816211,-#_74814023178a882a480104b00ddc842cp8@JPH2
9.72e-19FFCP PHASE1:Hg19::chr19:51538121..51538134,-#_74814023178a882a480104b00ddc842cp4@KLK12
9.72e-19FFCP PHASE2:Hg19::chr20:42816206..42816211,-#_74814023178a882a480104b00ddc842cp8@JPH2
9.72e-19FFCP PHASE2:Hg19::chr19:51538121..51538134,-#_74814023178a882a480104b00ddc842cp4@KLK12
8.69e-18FFCP PHASE1:Hg19::chr3:124535316..124535340,+#_c2238a2135fd215c2ed4656e3c2cda1bp@chr3:124535316..124535340, +
8.69e-18FFCP PHASE2:Hg19::chr6:151770193..151770196,-#_c2238a2135fd215c2ed4656e3c2cda1bp@chr6:151770193..151770196, -
8.69e-18FFCP PHASE2:Hg19::chr3:124535316..124535340,+#_c2238a2135fd215c2ed4656e3c2cda1bp@chr3:124535316..124535340, +
8.69e-18FFCP PHASE1:Hg19::chr5:59064162..59064173,-#_c2238a2135fd215c2ed4656e3c2cda1bp72@PDE4D
8.69e-18FFCP PHASE1:Hg19::chr1:44820685..44820695,-#_c2238a2135fd215c2ed4656e3c2cda1bp10@ERI3
8.69e-18FFCP PHASE2:Hg19::chr5:59064162..59064173,-#_c2238a2135fd215c2ed4656e3c2cda1bp72@PDE4D
8.69e-18FFCP PHASE1:Hg19::chr21:47410794..47410799,+#_c2238a2135fd215c2ed4656e3c2cda1bp@chr21:47410794..47410799, +
8.69e-18FFCP PHASE1:Hg19::chr6:151770193..151770196,-#_c2238a2135fd215c2ed4656e3c2cda1bp@chr6:151770193..151770196, -
8.69e-18FFCP PHASE2:Hg19::chr1:44820685..44820695,-#_c2238a2135fd215c2ed4656e3c2cda1bp10@ERI3
8.69e-18FFCP PHASE2:Hg19::chr21:47410794..47410799,+#_c2238a2135fd215c2ed4656e3c2cda1bp@chr21:47410794..47410799, +
1.03e-17FFCP PHASE1:Hg19::chr1:9970194..9970195,-#_9a2dec9f3250d4e9ffb8b5f4a4df71afp14@CTNNBIP1
1.03e-17FFCP PHASE2:Hg19::chr15:101459410..101459421,-#_9a2dec9f3250d4e9ffb8b5f4a4df71afp2@ENST00000560068
1.03e-17FFCP PHASE2:Hg19::chr1:9970194..9970195,-#_9a2dec9f3250d4e9ffb8b5f4a4df71afp14@CTNNBIP1
1.03e-17FFCP PHASE1:Hg19::chr5:79375654..79375674,+#_9a2dec9f3250d4e9ffb8b5f4a4df71afp@chr5:79375654..79375674, +
1.03e-17FFCP PHASE1:Hg19::chr15:101459410..101459421,-#_9a2dec9f3250d4e9ffb8b5f4a4df71afp2@ENST00000560068
1.03e-17FFCP PHASE1:Hg19::chr10:74020629..74020634,-#_9a2dec9f3250d4e9ffb8b5f4a4df71afp@chr10:74020629..74020634, -
1.03e-17FFCP PHASE1:Hg19::chr2:25383828..25383855,-#_9a2dec9f3250d4e9ffb8b5f4a4df71afp4@POMC
1.03e-17FFCP PHASE2:Hg19::chr5:79375654..79375674,+#_9a2dec9f3250d4e9ffb8b5f4a4df71afp@chr5:79375654..79375674, +
1.03e-17FFCP PHASE1:Hg19::chr10:43133595..43133606,-#_9a2dec9f3250d4e9ffb8b5f4a4df71afp@chr10:43133595..43133606, -
1.03e-17FFCP PHASE1:Hg19::chr11:65265332..65265342,+#_9a2dec9f3250d4e9ffb8b5f4a4df71afp19@MALAT1
1.03e-17FFCP PHASE2:Hg19::chr2:25383828..25383855,-#_9a2dec9f3250d4e9ffb8b5f4a4df71afp4@POMC
1.03e-17FFCP PHASE2:Hg19::chr10:74020629..74020634,-#_9a2dec9f3250d4e9ffb8b5f4a4df71afp@chr10:74020629..74020634, -
1.03e-17FFCP PHASE2:Hg19::chr10:43133595..43133606,-#_9a2dec9f3250d4e9ffb8b5f4a4df71afp@chr10:43133595..43133606, -
1.03e-17FFCP PHASE2:Hg19::chr11:65265332..65265342,+#_9a2dec9f3250d4e9ffb8b5f4a4df71afp19@MALAT1
2.59e-17FFCP PHASE2:Hg19::chr11:119039069..119039081,+#_2b76838760449956aa988ca81ac472dcp9@NLRX1
2.59e-17FFCP PHASE1:Hg19::chr11:119039069..119039081,+#_2b76838760449956aa988ca81ac472dcp9@NLRX1
2.09e-16FFCP PHASE1:Hg19::chr12:48164812..48164829,-#_a550ddda99cacfc54aa3c677c458e366p14@RAPGEF3
2.09e-16FFCP PHASE2:Hg19::chr12:48164812..48164829,-#_a550ddda99cacfc54aa3c677c458e366p14@RAPGEF3
2.64e-16FFCP PHASE1:Hg19::chr2:131669791..131669801,+#_6d42fb43dd4871154b951938ef7ac4f8p@chr2:131669791..131669801, +
2.64e-16FFCP PHASE2:Hg19::chr2:131669791..131669801,+#_6d42fb43dd4871154b951938ef7ac4f8p@chr2:131669791..131669801, +
3.32e-16FFCP PHASE2:Hg19::chr17:39742822..39742850,+#_61101da35bc3b1dfeffbf9f2af0610e9p@chr17:39742822..39742850, +
3.32e-16FFCP PHASE1:Hg19::chr17:39742822..39742850,+#_61101da35bc3b1dfeffbf9f2af0610e9p@chr17:39742822..39742850, +
3.59e-16FFCP PHASE2:Hg19::chr1:3591362..3591369,-#_735ed739ce41036349fd4dc68a56000dp@chr1:3591362..3591369, -
3.59e-16FFCP PHASE1:Hg19::chr1:3591362..3591369,-#_735ed739ce41036349fd4dc68a56000dp@chr1:3591362..3591369, -

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