Coexpression cluster:C24: Difference between revisions
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|tf_chipseq_enrich=SUZ12#23512;30:2.0019619538374:0.000343144087450145:0.00346659173430119 | |tf_chipseq_enrich=SUZ12#23512;30:2.0019619538374:0.000343144087450145:0.00346659173430119 | ||
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|tfbs_overrepresentation=0.987092,0.00194358,0.255936,0.343941,0.506369,0.999984,0.21913,0.377147,0.137035,0.77846,0.0213864,0.822896,0.0837584,0.434584,0.300006,0.257324,0.336818,0.899105,0.0123188,0.000185785,0.644815,0.885878,0.477967,0.523435,0.120378,0.823422,0.405117,0.282457,0.180862,0.723088,0.999413,0.546882,0.478312,0.0210054,0.988976,0.229023,1,0.420054,0.880635,0.653604,0.709738,0.28941,0.884089,0.000251354,0.471588,0.0139967,0.00531364,0.784702,0.000370432,0.92081,0.392236,0.529623,0.915836,0.995721,0.0568546,0.0027921,0.341118,0.949142,0.996089,0.595217,0.0779559,0.312156,0.582714,0.509477,0.00522717,0.9451,0.0563521,0.153977,0.997394,0.000810392,0.663112,0.676065,0.0143885,0.000212638,0.290488,0.000559834,0.115497,0.679156,0.0601134,0.0380308,0.539466,0.894218,0.000394715,0.141079,0.213969,0.999121,0.0808366,0.0170264,0.999467,0.276335,0.252813,0.000722174,0.997015,0.0131171,0.0699664,0.108348,0.121152,0.50547,0.00629997,0.43524,3.48209e-07,0.00771017,0.0724174,0.00408104,0.00103371,0.000542518,0.159388,0.0208614,0.97225,0.95888,0.836823,0.100816,0.828602,0.0387425,0.789637,0.159577,0.14883,0.298064,0.000694246,0.0100064,0.0122407,0.000795667,0.996123,0.000279765,0.95613,0.0840482,2.26041e-09,0.719766,0.12534,0.606747,2.07896e-06,0.00961319,0.612419,0.356826,0.635421,0.00101073,0.000302636,8.18889e-05,0.226859,0.629201,0.129709,0.00270485,0.16303,0.773396,0.867153,0.623455,0.306615,0.00220407,0.53496,0.00559423,0.105827,2.11711e-08,0.0166182,0.511547,0.960798,0.746652,0.127893,0.745168,0.00028787,0.753096,0.00648641,1.51277e-05,5.16308e-06,0.00294818,3.13763e-20,0.278734,0.0958466,0.0790841,0.15929,0.000219223,0.0203687,0.00226699,0.00115935,0.323979,0.208345,0.49699,0.0077989,0.918847,0.587314,0.685753,0.026246,0.862622,0.0954574,0.00144879,0.288052,2.95119e-07,0.107684,0.942296,0.200906,0.0140465,0.00624796,0.770895,0.993579,0.51859,0.0448675,0.160721,0.0633135,0.0281815,0.00228913,0.675205,0.0355774,0.303423,0.00688266,7.39046e-06,0.0147962,0.197576,0.0686055,0.0114548,0.189068,0.311349,0.206154,0.0974378,0.848077,0.992693,0.212221,0.000723744,0.0340046,3.54372e-09,0.561587,0.756528,0.296758,0.0124909,0.217204,0.947375,0.1162,0.901513,0.987009,0.106164,0.0736206,7.04169e-05,0.999992,0.105337,0.000316019,0.522928,0.195606,0.984204,0.10742,0.00217371,0.822089,0.737208,0.994066,0.999952,0.000234333,0.00307407,0.033558,0.511189,0.00224259,0.87242,0.183349,0.268242,0.999016,0.93779,0.750585,0.0223894,0.73865,0.00717839,0.819951,0.996129,0.353942,0.366388,0.95674,0.529956,0.499257,0.286448,0.000127113,0.00359787,0.000333417,0.768293,0.626308,0.993905,0.370514,0.0452674,0.999394,0.999999,0.00971387,0.380737,0.215332,0.00147387,0.326316,0.454205,0.178812,0.999935,0.235019,1,0.56383,0.304634,0.221963,0.239683,0.0393233,0.129807,0.00085606,0.00202737,0.905913,0.596151,0.553765,0.0419502,0.00256623,0.000531901,0.000110584,0.0128687,0.433461,0.0584905,0.0182902,0.0721839,0.0763268,0.9352,4.67409e-05,0.496834,1.85446e-08,0.00331813,3.3767e-10,0.980637,0.979814,0.51308,0.0517156,0.00181706,0.193012,0.065831,0.0781544,0.105297,2.88662e-05,0.0620859,0.0176973,0.338504,0.00124169,0.492839,0.0275251,0.619834,0.0910655,0.919241,0.211598,0.28259,0.737784,0.708897,0.114857,0.476262,0.0809436,0.00188644,0.874244,0.0104275,0.613546,0.999994,0.569083,0.410359,0.725978,0.130768,0.679007,0.182997,0.268723,0.927426,0.0344287,2.53602e-05,0.0268351,0.00122507,0.0225508,0.329712,0.380157,0.160391,6.73714e-09,0.0258869,0.51648,0.225394,0.462147,0.866859,0.00945166,0.456887,0.00110237,0.862298,0.161926,0.0242273,0.999984,0.0788971,0.000495797,0.666422,0.844687,0.988632,0.379461,0.94782,0.18344,0.844533,0.771789,0.00894382,0.830685,5.59751e-24,0.10941,0.991883,0.69865,0.000943328,0.15985,0.267014,0.155024,0.836942,0.0572683,0.247996,0.800027,1,0.00451246,0.0715681,0.00320409,0.988562,0.444067,0.988391,0.0130195,0.00381955,0.00599355,0.0979873,0.000801372,0.982182,0.0249287,0.302015,0.532143,0.00989281,0.0705244,0.942628,6.35926e-08,0.529045,0.0824607,0.000165111,0.0611766,2.88046e-06,0.913312,0.999492,0.862633,0.00828822,0.00696974,0.0049738,0.000791391,0.83359,3.34302e-05,0.190335,0.00305703,0.573676,0.0186815,0.999578,0.570658,0.0102791,0.0198773,0.482295,0.00957851,0.724153,0.00178924,0.100137,0.126594,0.496341,0.0348107,0.207809,0.205984,0.966146,0.391207,0.00785306,1.88888e-07,0.00287017,0.173098,0.0595126,0.991035,0.811243,0.721487,0.465822,0.93843,1.06983e-97,0.0296541,0.852461,0.151153,0.998049,0.8164,1,0.323968,0.0128648,0.884652,0.000553698,0.0042148,0.00552098,0.0353818,0.0914643,0.998647,0.362677,1,0.472481,0.858647,0.857547,1,0.0597773,0.99599,0.00324384,0.000497093,0.114593,0.0812443,0.0292203,2.99051e-06,4.59138e-05,0.255355,0.0387816,9.4321e-06,0.999956,0.260454,0.000580612,0.22191,0.00167871,0.816892,0.230403,0.00299449,0.202564,0.99476,0.890615,0.0055242,0.999832,0.261588,0.262463,0.806028,2.61257e-08,0.37289,0.521536,0.950136,0.999696,0.00356378,0.941203,0.0121762,1.16359e-05,0.0513815,0.340197,0.993518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| ||
|tfbs_overrepresentation_for_novel_motifs=0.0275189,0.000991208,0.000507363,0.592256,0.620944,0.0727275,0.0119217,0.033391,1.35345,0.118505,0.00212095,0.480902,0.016956,0.00807427,0.0659061,0.223273,0.0563153,0.176598,0.642323,0.131854,0.438365,0.549119,7.79243e-05,0.153506,0.0224778,0.134708,1.10532,0.0281927,0.0976177,0.119906,0.0641641,0.102117,0.0227776,0.0642808,3.34841e-08,0.212363,3.76135e-06,0.0750884,0.217898,0.117889,0.672875,6.75263e-05,0.136319,0.718958,0.00139548,0.000158813,0.00748658,0.0190202,0.121601,0.00139235,0.00308836,0.000486544,0.128641,0.0776293,0.0537322,0.00894176,0.166524,0.2645,0.135553,0.00134619,0.57698,0.00472763,0.00663243,0.00504028,0.0348744,0.0084283,0.70287,0.438697,0.259425,0.536325,0.0157935,0.881308,1.48097e-09,1.12215,0.000479661,0.0611114,0.0693794,0.0392365,1.56816,0.407897,0.137708,0.00218016,0.279548,0.100438,0.011099,3.85731e-16,26.9618,0.535958,0.110887,0.157538,0.0316555,0.186574,1.05632,0.135162,0.00267355,0.4336,0.382546,0.0988168,0.0141724,0.862175,0.385438,0.689469,0.645315,0.837711,0.0822773,2.96701e-07,0.0266967,0.0278541,0.011084,0.00394571,1.07347,0.014871,0.0204875,0.00539698,0.479809,0.75355,9.4772e-06,0.547135,0.514801,0.15315,1.31137,0.195426,0.00444099,0.494667,0.249279,0.421626,0.0719016,0.056507,0.345314,0.153558,0.67839,0.671627,2.06818,0.893311,0.925524,0.352473,0.575758,1.3354,0.12686,1.27016,0.0542794,0.816841,1.78056,0.212093,0.378381,0.108684,0.972998,0.152398,0.512572,0.00156016,0.00156681,9.92846e-11,0.389537,0.00413443,0.254811,0.396747,0.0139797,25.9988,110.856,0.00156558,0.421862,0.0130406,0.0511821,0.0975904,0.0181608,0.0705321,1.99723,0.708285,8.71666e-07 | |||
}} | }} | ||
Revision as of 13:07, 26 November 2012
Full id: C24_pineal_eye_retina_retinoblastoma_medulloblastoma_small_cerebral
Phase1 CAGE Peaks
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| p.value | FDR | nGenes | nPathway | Name |
|---|---|---|---|---|
| 0.000470698198345789 | 0.0372439949441106 | 6 | 177 | Calcium signaling pathway (KEGG):04020 |
| 0.000694917271096551 | 0.0486926421382142 | 5 | 126 | Glutamatergic synapse (KEGG):04724 |
| 5.19993609451351e-07 | 0.000329155954782705 | 5 | 29 | Phototransduction (KEGG):04744 |
| 0.000769236052736402 | 0.0486926421382142 | 4 | 74 | Arrhythmogenic right ventricular cardiomyopathy (ARVC) (KEGG):05412 |
| 2.02341748965745e-05 | 0.00320205817738292 | 7 | 149 | Calcium Regulation in the Cardiac Cell (Wikipathways):WP536 |
| 8.38705268464731e-05 | 0.00884834058230291 | 5 | 80 | Opioid Signalling (Reactome):REACT_15295 |
| 1.55850127790407e-05 | 0.00320205817738292 | 11 | 401 | Transmembrane transport of small molecules (Reactome):REACT_15518 |
| 1.48424133770203e-05 | 0.00320205817738292 | 8 | 197 | Synaptic Transmission (Reactome):REACT_13685 |
| 7.12702286791639e-05 | 0.00884834058230291 | 6 | 125 | Integration of energy metabolism (Reactome):REACT_1505 |
| 0.000106862696077304 | 0.00966344094527616 | 3 | 17 | {CNGB1,17} (Static Module):NA |
Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0032501 | multicellular organismal process | 3.21600558606932e-30 |
| GO:0003008 | system process | 7.95109097205851e-25 |
| GO:0050953 | sensory perception of light stimulus | 1.98325390366724e-20 |
| GO:0007601 | visual perception | 1.98325390366724e-20 |
| GO:0050877 | neurological system process | 6.47338829556001e-20 |
| GO:0048731 | system development | 7.35407996784593e-17 |
| GO:0048856 | anatomical structure development | 4.09448474032261e-14 |
| GO:0007275 | multicellular organismal development | 3.40457690032235e-12 |
| GO:0007600 | sensory perception | 4.15823565430743e-09 |
| GO:0032502 | developmental process | 2.11363271531131e-08 |
| GO:0007154 | cell communication | 2.51442961876774e-08 |
| GO:0005515 | protein binding | 2.51442961876774e-08 |
| GO:0007399 | nervous system development | 5.35745341702648e-08 |
| GO:0050906 | detection of stimulus during sensory perception | 5.35745341702648e-08 |
| GO:0007165 | signal transduction | 1.75731639974727e-07 |
| GO:0044459 | plasma membrane part | 1.86821063255191e-07 |
| GO:0050962 | detection of light stimulus during sensory perception | 1.92685678776827e-07 |
| GO:0050908 | detection of light stimulus during visual perception | 1.92685678776827e-07 |
| GO:0009584 | detection of visible light | 2.22378628281634e-07 |
| GO:0048699 | generation of neurons | 2.4058932567951e-07 |
| GO:0009583 | detection of light stimulus | 2.43513381744392e-07 |
| GO:0005886 | plasma membrane | 3.96114173207044e-07 |
| GO:0022008 | neurogenesis | 4.76766488549825e-07 |
| GO:0048666 | neuron development | 6.17649986502183e-07 |
| GO:0030182 | neuron differentiation | 6.42749053228574e-07 |
| GO:0009582 | detection of abiotic stimulus | 1.14893772163572e-06 |
| GO:0051606 | detection of stimulus | 1.4725491208106e-06 |
| GO:0009416 | response to light stimulus | 1.54912374185552e-06 |
| GO:0009653 | anatomical structure morphogenesis | 1.62655437755612e-06 |
| GO:0048869 | cellular developmental process | 1.79162047950077e-06 |
| GO:0030154 | cell differentiation | 1.79162047950077e-06 |
| GO:0009581 | detection of external stimulus | 1.79162047950077e-06 |
| GO:0000902 | cell morphogenesis | 2.4140732651384e-06 |
| GO:0032989 | cellular structure morphogenesis | 2.4140732651384e-06 |
| GO:0031175 | neurite development | 2.50524099957115e-06 |
| GO:0007602 | phototransduction | 3.94802607960166e-06 |
| GO:0048858 | cell projection morphogenesis | 4.28058031665663e-06 |
| GO:0032990 | cell part morphogenesis | 4.28058031665663e-06 |
| GO:0030030 | cell projection organization and biogenesis | 4.28058031665663e-06 |
| GO:0009314 | response to radiation | 5.01910029320344e-06 |
| GO:0005509 | calcium ion binding | 2.10724353222121e-05 |
| GO:0000904 | cellular morphogenesis during differentiation | 2.15967972377662e-05 |
| GO:0016020 | membrane | 3.41672814086081e-05 |
| GO:0005856 | cytoskeleton | 8.40890823476201e-05 |
| GO:0048513 | organ development | 8.47580469221347e-05 |
| GO:0007166 | cell surface receptor linked signal transduction | 0.00011168558792136 |
| GO:0009628 | response to abiotic stimulus | 0.000116634642217725 |
| GO:0007409 | axonogenesis | 0.000162554476856721 |
| GO:0046530 | photoreceptor cell differentiation | 0.000170430943024622 |
| GO:0005578 | proteinaceous extracellular matrix | 0.000184565216545833 |
| GO:0048667 | neuron morphogenesis during differentiation | 0.000201523633850102 |
| GO:0048812 | neurite morphogenesis | 0.000201523633850102 |
| GO:0008277 | regulation of G-protein coupled receptor protein signaling pathway | 0.00027986195406269 |
| GO:0016358 | dendrite development | 0.000281865007043966 |
| GO:0008081 | phosphoric diester hydrolase activity | 0.000422572076103286 |
| GO:0044425 | membrane part | 0.000495940174002962 |
| GO:0065007 | biological regulation | 0.000495940174002962 |
| GO:0016043 | cellular component organization and biogenesis | 0.000555380916604903 |
| GO:0004434 | inositol or phosphatidylinositol phosphodiesterase activity | 0.000608085847542492 |
| GO:0004435 | phosphoinositide phospholipase C activity | 0.000608085847542492 |
| GO:0030054 | cell junction | 0.00113610306622118 |
| GO:0003779 | actin binding | 0.00130965789126396 |
| GO:0051179 | localization | 0.00139693478392947 |
| GO:0004629 | phospholipase C activity | 0.00145622042874337 |
| GO:0004620 | phospholipase activity | 0.00210717243629538 |
| GO:0022610 | biological adhesion | 0.00225222727809449 |
| GO:0007155 | cell adhesion | 0.00225222727809449 |
| GO:0030551 | cyclic nucleotide binding | 0.00225253308185017 |
| GO:0048468 | cell development | 0.00232790458950567 |
| GO:0050789 | regulation of biological process | 0.00255672192156184 |
| GO:0045165 | cell fate commitment | 0.00309196646656464 |
| GO:0031252 | leading edge | 0.00321841352634218 |
| GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | 0.00324785037767783 |
| GO:0016298 | lipase activity | 0.00408403803082465 |
| GO:0007173 | epidermal growth factor receptor signaling pathway | 0.00473253104846133 |
| GO:0008589 | regulation of smoothened signaling pathway | 0.00484439401825361 |
| GO:0001754 | eye photoreceptor cell differentiation | 0.00484439401825361 |
| GO:0009986 | cell surface | 0.00484439401825361 |
| GO:0016323 | basolateral plasma membrane | 0.00552877167951393 |
| GO:0009966 | regulation of signal transduction | 0.00552877167951393 |
| GO:0007423 | sensory organ development | 0.00561505496314517 |
| GO:0001822 | kidney development | 0.00561505496314517 |
| GO:0006811 | ion transport | 0.00591451383144133 |
| GO:0005834 | heterotrimeric G-protein complex | 0.00594759789115444 |
| GO:0044456 | synapse part | 0.00647784965717816 |
| GO:0007186 | G-protein coupled receptor protein signaling pathway | 0.00647784965717816 |
| GO:0044464 | cell part | 0.00650386629032138 |
| GO:0051015 | actin filament binding | 0.00663860732936017 |
| GO:0042578 | phosphoric ester hydrolase activity | 0.00672743551776047 |
| GO:0001655 | urogenital system development | 0.00699691032016755 |
| GO:0001726 | ruffle | 0.008568304472239 |
| GO:0008092 | cytoskeletal protein binding | 0.00923244268977227 |
| GO:0030553 | cGMP binding | 0.0102906970867074 |
| GO:0019002 | GMP binding | 0.0102906970867074 |
| GO:0001654 | eye development | 0.0106587896149039 |
| GO:0004091 | carboxylesterase activity | 0.0113583833544675 |
| GO:0022836 | gated channel activity | 0.0117944374846442 |
| GO:0046928 | regulation of neurotransmitter secretion | 0.0118137396867808 |
| GO:0019897 | extrinsic to plasma membrane | 0.012255591742805 |
| GO:0044421 | extracellular region part | 0.0126993047356646 |
| GO:0005217 | intracellular ligand-gated ion channel activity | 0.0135114730344158 |
| GO:0004871 | signal transducer activity | 0.0147295675342285 |
| GO:0060089 | molecular transducer activity | 0.0147295675342285 |
| GO:0007167 | enzyme linked receptor protein signaling pathway | 0.0147872460395329 |
| GO:0007224 | smoothened signaling pathway | 0.0151231357458748 |
| GO:0019899 | enzyme binding | 0.0157767846895647 |
| GO:0005085 | guanyl-nucleotide exchange factor activity | 0.0166936490843736 |
| GO:0050794 | regulation of cellular process | 0.0176333742073719 |
| GO:0051046 | regulation of secretion | 0.0179845492051726 |
| GO:0007010 | cytoskeleton organization and biogenesis | 0.0188184685272245 |
| GO:0007405 | neuroblast proliferation | 0.0212123448091287 |
| GO:0048471 | perinuclear region of cytoplasm | 0.0221077817879168 |
| GO:0009881 | photoreceptor activity | 0.0233801580929045 |
| GO:0016477 | cell migration | 0.0250944581249322 |
| GO:0005737 | cytoplasm | 0.0251713650550023 |
| GO:0001657 | ureteric bud development | 0.0251713650550023 |
| GO:0019905 | syntaxin binding | 0.0251713650550023 |
| GO:0016042 | lipid catabolic process | 0.0274261961948432 |
| GO:0006940 | regulation of smooth muscle contraction | 0.0274261961948432 |
| GO:0045211 | postsynaptic membrane | 0.0292064707572489 |
| GO:0008283 | cell proliferation | 0.0294904349837123 |
| GO:0000149 | SNARE binding | 0.0294904349837123 |
| GO:0009887 | organ morphogenesis | 0.030747741707863 |
| GO:0031114 | regulation of microtubule depolymerization | 0.030747741707863 |
| GO:0007026 | negative regulation of microtubule depolymerization | 0.030747741707863 |
| GO:0048518 | positive regulation of biological process | 0.030747741707863 |
| GO:0007019 | microtubule depolymerization | 0.030747741707863 |
| GO:0031111 | negative regulation of microtubule polymerization or depolymerization | 0.030747741707863 |
| GO:0006836 | neurotransmitter transport | 0.030747741707863 |
| GO:0001505 | regulation of neurotransmitter levels | 0.030747741707863 |
| GO:0046534 | positive regulation of photoreceptor cell differentiation | 0.030747741707863 |
| GO:0032835 | glomerulus development | 0.030747741707863 |
| GO:0031593 | polyubiquitin binding | 0.030747741707863 |
| GO:0050254 | rhodopsin kinase activity | 0.030747741707863 |
| GO:0004059 | aralkylamine N-acetyltransferase activity | 0.030747741707863 |
| GO:0005307 | choline:sodium symporter activity | 0.030747741707863 |
| GO:0046532 | regulation of photoreceptor cell differentiation | 0.030747741707863 |
| GO:0042706 | eye photoreceptor cell fate commitment | 0.030747741707863 |
| GO:0008292 | acetylcholine biosynthetic process | 0.030747741707863 |
| GO:0043033 | isoamylase complex | 0.030747741707863 |
| GO:0046552 | photoreceptor cell fate commitment | 0.030747741707863 |
| GO:0005223 | intracellular cGMP activated cation channel activity | 0.030747741707863 |
| GO:0031129 | inductive cell-cell signaling | 0.030747741707863 |
| GO:0060001 | minus-end directed microfilament motor activity | 0.030747741707863 |
| GO:0005597 | collagen type XVI | 0.030747741707863 |
| GO:0009642 | response to light intensity | 0.030747741707863 |
| GO:0003834 | beta-carotene 15,15'-monooxygenase activity | 0.030747741707863 |
| GO:0051234 | establishment of localization | 0.030747741707863 |
| GO:0001656 | metanephros development | 0.0314872689636071 |
| GO:0022834 | ligand-gated channel activity | 0.0326590744196053 |
| GO:0015276 | ligand-gated ion channel activity | 0.0326590744196053 |
| GO:0006936 | muscle contraction | 0.0329321333079804 |
| GO:0003012 | muscle system process | 0.0329321333079804 |
| GO:0006928 | cell motility | 0.0332220363011305 |
| GO:0051674 | localization of cell | 0.0332220363011305 |
| GO:0046903 | secretion | 0.0334252211438388 |
| GO:0007214 | gamma-aminobutyric acid signaling pathway | 0.0345164556287797 |
| GO:0048592 | eye morphogenesis | 0.0345164556287797 |
| GO:0031267 | small GTPase binding | 0.0345164556287797 |
| GO:0005200 | structural constituent of cytoskeleton | 0.0345164556287797 |
| GO:0042472 | inner ear morphogenesis | 0.0367694471864249 |
| GO:0006810 | transport | 0.0415354532550935 |
| GO:0031110 | regulation of microtubule polymerization or depolymerization | 0.0415354532550935 |
| GO:0007623 | circadian rhythm | 0.0415354532550935 |
| GO:0048523 | negative regulation of cellular process | 0.0420619110771119 |
| GO:0005216 | ion channel activity | 0.042602722371742 |
| GO:0030001 | metal ion transport | 0.042602722371742 |
| GO:0007268 | synaptic transmission | 0.042602722371742 |
| GO:0005624 | membrane fraction | 0.042602722371742 |
| GO:0006816 | calcium ion transport | 0.042602722371742 |
| GO:0016788 | hydrolase activity, acting on ester bonds | 0.0440528346169432 |
| GO:0022838 | substrate specific channel activity | 0.04411784452899 |
| GO:0042471 | ear morphogenesis | 0.0448617240714105 |
| GO:0015629 | actin cytoskeleton | 0.0450089508477441 |
| GO:0051020 | GTPase binding | 0.0453292637728311 |
| GO:0005261 | cation channel activity | 0.0453292637728311 |
| GO:0031226 | intrinsic to plasma membrane | 0.0454276931797191 |
| GO:0022803 | passive transmembrane transporter activity | 0.0456805817529686 |
| GO:0015267 | channel activity | 0.0456805817529686 |
| GO:0031109 | microtubule polymerization or depolymerization | 0.0458717163607918 |
| GO:0030695 | GTPase regulator activity | 0.0459236351144342 |
| GO:0005915 | zonula adherens | 0.048114122482756 |
| GO:0004133 | glycogen debranching enzyme activity | 0.048114122482756 |
| GO:0001543 | ovarian follicle rupture | 0.048114122482756 |
| GO:0043297 | apical junction assembly | 0.048114122482756 |
| GO:0004135 | amylo-alpha-1,6-glucosidase activity | 0.048114122482756 |
| GO:0045880 | positive regulation of smoothened signaling pathway | 0.048114122482756 |
| GO:0004134 | 4-alpha-glucanotransferase activity | 0.048114122482756 |
| GO:0048519 | negative regulation of biological process | 0.0484792384655927 |
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>
| Ontology term | p-value | n |
|---|---|---|
| pineal body | 1.05e-79 | 2 |
| regional part of epithalamus | 1.05e-79 | 2 |
| secretory circumventricular organ | 1.05e-79 | 2 |
| circumventricular organ | 1.05e-79 | 2 |
| epithalamus | 1.05e-79 | 2 |
| gland of diencephalon | 1.48e-40 | 4 |
| neuroendocrine gland | 1.48e-40 | 4 |
| regional part of diencephalon | 1.48e-40 | 4 |
| retina | 3.55e-27 | 6 |
| photoreceptor array | 3.55e-27 | 6 |
| posterior segment of eyeball | 3.55e-27 | 6 |
| diencephalon | 1.02e-23 | 7 |
| future diencephalon | 1.02e-23 | 7 |
| eye | 1.10e-17 | 21 |
| visual system | 1.10e-17 | 21 |
| sense organ | 1.38e-15 | 24 |
| sensory system | 1.38e-15 | 24 |
| entire sense organ system | 1.38e-15 | 24 |
| pre-chordal neural plate | 6.50e-11 | 61 |
| camera-type eye | 6.42e-09 | 20 |
| simple eye | 6.42e-09 | 20 |
| immature eye | 6.42e-09 | 20 |
| ocular region | 6.42e-09 | 20 |
| eyeball of camera-type eye | 6.42e-09 | 20 |
| optic cup | 6.42e-09 | 20 |
| optic vesicle | 6.42e-09 | 20 |
| eye primordium | 6.42e-09 | 20 |
| neural plate | 2.59e-08 | 82 |
| presumptive neural plate | 2.59e-08 | 82 |
| face | 3.39e-08 | 22 |
| neurectoderm | 5.87e-08 | 86 |
Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
|
{{{tfbs_overrepresentation_jaspar}}} |
ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data
(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)
| TF | #promoters | Enrichment | p-value | q-value |
|---|---|---|---|---|
| SUZ12#23512 | 30 | 2.0019619538374 | 0.000343144087450145 | 0.00346659173430119 |
Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data
