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MCL coexpression mm9:1067

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Phase1 CAGE Peaks

 Short description
Mm9::chr11:3166345..3166356,-p2@Drg1
Mm9::chr11:57981969..57982046,-p1@Gemin5
Mm9::chr11:82594646..82594726,+p1@Lig3
Mm9::chr19:42007766..42007809,-p1@Exosc1
Mm9::chr2:30141926..30141962,+p1@Nup188
Mm9::chr3:137806393..137806441,+p1@Rg9mtd2
Mm9::chr7:52650585..52650599,-p2@Snrnp70


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0003723RNA binding0.00283615803609444
GO:0006396RNA processing0.00986854879041573
GO:0044428nuclear part0.00986854879041573
GO:0005634nucleus0.0170882624622196
GO:0003676nucleic acid binding0.0229985721377707
GO:0005681spliceosome0.0229985721377707
GO:0003909DNA ligase activity0.0229985721377707
GO:0003910DNA ligase (ATP) activity0.0229985721377707
GO:0016886ligase activity, forming phosphoric ester bonds0.0255497690801792
GO:0032991macromolecular complex0.0417743685416616
GO:0000178exosome (RNase complex)0.0417743685416616
GO:0008175tRNA methyltransferase activity0.042115565933889
GO:0045576mast cell activation0.0424031109006837



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
primordium5.71e-10134
anterior region of body1.61e-0843
body cavity1.62e-0837
body cavity or lining1.62e-0837
hemopoietic organ1.83e-0829
immune organ1.83e-0829
body cavity precursor4.11e-0838
gonad1.20e-0718
gonad primordium1.20e-0718
anatomical cavity1.58e-0739
external genitalia3.61e-0717
indifferent external genitalia3.61e-0717
indifferent gonad3.61e-0717
mixed endoderm/mesoderm-derived structure5.14e-0735


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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