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Coexpression cluster:C208

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Full id: C208_skin_amniotic_papillotubular_salivary_umbilical_Alveolar_serous



Phase1 CAGE Peaks

Hg19::chr10:94301107..94301111,-p18@IDE
Hg19::chr11:105010477..105010516,-p1@CARD18
Hg19::chr11:65779425..65779509,+p1@CST6
Hg19::chr11:65779676..65779683,+p12@CST6
Hg19::chr12:52685312..52685319,-p11@KRT81
Hg19::chr12:52695617..52695623,+p4@KRT86
Hg19::chr12:52715179..52715182,-p1@KRT83
Hg19::chr12:52761262..52761267,-p1@KRT85
Hg19::chr12:52946923..52946931,-p1@KRT71
Hg19::chr12:52967622..52967628,-p1@KRT74
Hg19::chr12:52995291..52995294,-p5@KRT72
Hg19::chr12:53097305..53097310,-p1@KRT77
Hg19::chr12:53228091..53228096,-p1@KRT79
Hg19::chr16:56598984..56598990,+p1@MT4
Hg19::chr17:20687950..20687982,+p1@SCDP1
Hg19::chr17:38911580..38911584,-p1@KRT25
Hg19::chr17:38938796..38938803,-p1@KRT27
Hg19::chr17:38956205..38956214,-p1@KRT28
Hg19::chr17:39165376..39165381,-p1@KRTAP3-1
Hg19::chr17:39191123..39191127,-p1@KRTAP1-3
Hg19::chr17:39254391..39254395,-p1@KRTAP4-8
Hg19::chr17:39274621..39274626,-p1@KRTAP4-11
Hg19::chr17:39280430..39280436,-p1@KRTAP4-12
Hg19::chr17:39296794..39296798,-p1@KRTAP4-6
Hg19::chr17:39306068..39306077,-p1@KRTAP4-5
Hg19::chr17:39316998..39317001,-p1@KRTAP4-4
Hg19::chr17:39324471..39324474,-p1@KRTAP4-3
Hg19::chr17:39334471..39334474,-p1@KRTAP4-2
Hg19::chr17:39341160..39341165,-p1@KRTAP4-1
Hg19::chr17:39388700..39388702,+p1@KRTAP9-3
p1@KRTAP9-9
Hg19::chr17:39394250..39394253,+p1@KRTAP9-8
Hg19::chr17:39465536..39465562,-p1@KRTAP16-1
Hg19::chr17:39471958..39471963,-p1@KRTAP17-1
Hg19::chr17:39507076..39507080,-p1@KRT33A
Hg19::chr17:39553852..39553863,-p1@KRT31
Hg19::chr17:39637401..39637404,-p1@KRT35
Hg19::chr17:48261972..48261979,-p@chr17:48261972..48261979
-
Hg19::chr17:48262782..48262783,-p55@COL1A1
Hg19::chr18:61209598..61209607,+p@chr18:61209598..61209607
+
Hg19::chr18:61209634..61209647,+p@chr18:61209634..61209647
+
Hg19::chr18:61209658..61209665,+p@chr18:61209658..61209665
+
Hg19::chr19:24140738..24140740,-p1@uc002nrp.1
Hg19::chr19:46753446..46753471,-p@chr19:46753446..46753471
-
Hg19::chr1:152061537..152061542,-p1@TCHHL1
Hg19::chr1:152087919..152087921,-p1@TCHH
Hg19::chr1:152286909..152286919,-p2@FLG
Hg19::chr1:152287109..152287120,-p3@FLG
Hg19::chr1:152332480..152332484,-p1@FLG2
Hg19::chr1:152483278..152483280,+p1@LCE5A
Hg19::chr1:152627927..152627931,+p1@LINC00302
Hg19::chr1:152635854..152635860,+p1@LCE2D
Hg19::chr1:152691067..152691070,+p1@C1orf68
Hg19::chr1:152815327..152815336,+p1@LCE6A
Hg19::chr1:152943122..152943128,+p1@SPRR4
Hg19::chr1:153232160..153232165,+p1@LOR
Hg19::chr1:153522562..153522578,-p11@S100A4
Hg19::chr1:1567038..1567075,+p4@MMP23B
Hg19::chr1:179242347..179242350,+p@chr1:179242347..179242350
+
Hg19::chr21:31655265..31655269,-p1@KRTAP24-1
Hg19::chr21:31852683..31852688,-p1@KRTAP19-1
Hg19::chr21:31874456..31874461,-p1@KRTAP19-5
Hg19::chr21:32185588..32185592,-p1@KRTAP8-1
Hg19::chr21:32202074..32202079,-p1@KRTAP7-1
Hg19::chr21:32253891..32253899,-p1@KRTAP11-1
Hg19::chr21:45978676..45978679,-p1@KRTAP10-3
Hg19::chr21:46047009..46047014,+p1@KRTAP10-9
Hg19::chr21:46132193..46132201,-p@chr21:46132193..46132201
-
Hg19::chr2:189849488..189849548,+p@chr2:189849488..189849548
+
Hg19::chr3:100238112..100238123,+p9@TMEM45A
Hg19::chr4:7436623..7436650,-p1@PSAPL1
Hg19::chr5:132460176..132460179,-p@chr5:132460176..132460179
-
Hg19::chr6:169582924..169582941,-p1@uc011egv.1
Hg19::chr6:31106840..31106848,-p1@PSORS1C2
Hg19::chr8:82373809..82373815,-p1@FABP9


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0005882intermediate filament1.1208404948315e-59
GO:0045111intermediate filament cytoskeleton1.1208404948315e-59
GO:0044430cytoskeletal part3.9119482783705e-39
GO:0005856cytoskeleton5.76371606942739e-38
GO:0044446intracellular organelle part2.17698466243593e-29
GO:0044422organelle part2.25177511944484e-29
GO:0043232intracellular non-membrane-bound organelle7.68133773291025e-27
GO:0043228non-membrane-bound organelle7.68133773291025e-27
GO:0045095keratin filament1.45046114508371e-17
GO:0008544epidermis development2.26158647486084e-15
GO:0007398ectoderm development4.96550089454214e-15
GO:0009888tissue development1.54617141935801e-11
GO:0043229intracellular organelle6.11875480359721e-10
GO:0043226organelle6.11875480359721e-10
GO:0044424intracellular part1.04983647492565e-09
GO:0031424keratinization3.47712308664615e-08
GO:0009913epidermal cell differentiation1.22758567921542e-07
GO:0048730epidermis morphogenesis2.10050284994915e-07
GO:0005622intracellular3.24635649567415e-07
GO:0048729tissue morphogenesis7.45577359694037e-07
GO:0048513organ development7.940099712924e-06
GO:0032502developmental process9.57971456732683e-05
GO:0048731system development0.000170398828538472
GO:0048856anatomical structure development0.000251224646956548
GO:0007275multicellular organismal development0.000866833468931428
GO:0001533cornified envelope0.00280408857071443
GO:0009653anatomical structure morphogenesis0.00539239046622906
GO:0004231insulysin activity0.00774612961119495
GO:0044464cell part0.0149983939589835
GO:0005584collagen type I0.0201504240562489
GO:0008147structural constituent of bone0.0248826537274661
GO:0005200structural constituent of cytoskeleton0.0287101500655512
GO:0009898internal side of plasma membrane0.0332171421029089
GO:0032501multicellular organismal process0.0465018647410683



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Cell Type
Ontology termp-valuen
non-terminally differentiated cell9.12e-12180
fibroblast7.18e-0975
Uber Anatomy
Ontology termp-valuen
organism subdivision1.02e-14365
multi-cellular organism9.64e-13659
surface structure1.87e-1295
mesenchyme1.00e-11238
entire embryonic mesenchyme1.00e-11238
trunk3.26e-11216
trunk mesenchyme1.42e-10143
endoderm-derived structure3.94e-10169
endoderm3.94e-10169
presumptive endoderm3.94e-10169
organ6.65e-10511
multi-tissue structure7.27e-10347
anatomical system3.02e-09625
anatomical group4.83e-09626
organ component layer1.47e-0857
integument4.70e-0845
integumental system4.70e-0845
digestive system4.78e-08155
digestive tract4.78e-08155
primitive gut4.78e-08155
embryo1.51e-07612
skin of body2.57e-0740
endo-epithelium2.95e-0782
embryonic structure5.06e-07605
developing anatomical structure5.06e-07605
germ layer9.54e-07604
embryonic tissue9.54e-07604
presumptive structure9.54e-07604
epiblast (generic)9.54e-07604


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

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